- Search results for 1173-1
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5 products were found matching "1173-1"!
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Item number: Cay23782-5
Mexiletine is a voltage-gated sodium channel blocker and class Ib antiarrhythmic agent that preferentially binds to open/inactive channels. It inhibits aconitine-induced dysrhythmias in mice with ED50 values of 57 and 107 mg/kg for intraperitoneal and oral administration, respectively. Mexiletine decreases or...
Keywords: | Ko 1173, 1-(2,6-dimethylphenoxy)-2-propanamine, monohydrochloride |
Application: | Sodium channel blocker |
CAS | 5370-01-4 |
MW: | 215.7 D |
From 43.00€
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Item number: Cay11731-10
Bosentan is an antagonist of the endothelin receptors type A (Ki = 6.5 nM) and type B (Ki = 340 nM).Formal Name: 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide. CAS Number: 147536-97-8. Synonyms: Ro 47-0203. Molecular Formula: C27H29N5O6S. Formula Weight:...
Keywords: | Ro 47-0203, 4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide |
Application: | Endothelin receptor antagonist |
CAS | 147536-97-8 |
MW: | 551.6 D |
From 44.00€
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Item number: Cay11173-1
Glucose transporter 1 (Glut1) is an inducible carrier of pentoses and hexoses, including glucose. STF-31 is an inhibitor of Glut1 (IC50 = ~1 µM) that blocks glucose uptake. It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress Glut1. Although STF-31 binds Glut1,...
Keywords: | 4-[[[[4-(1,1-dimethylethyl)phenyl]sulfonyl]amino]methyl]-N-3-pyridinyl-benzamide |
Application: | GLUT1 inhibitor |
CAS | 724741-75-7 |
MW: | 423.5 D |
From 60.00€
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Item number: ABE-42-1173-200
HSP70 genes encode abundant heat-inducible 70-kDa HSPs (HSP70s). In most eukaryotes HSP70 genes exist as part of a multigene family. They are found in most cellular compartments of eukaryotes including nuclei, mitochondria, chloroplasts, the endoplasmic reticulum and the cytosol, as well as in bacteria. The genes...
Keywords: | Anti-HSPA1A, Anti-HSP70.1, Anti-HSP70-1, Anti-Heat shock 70 kDa protein 1, Anti-Heat shock 70 kDa protein 1A, Anti-HSP70... |
Application: | WB, ICC/IF, ELISA |
Host: | Mouse |
Species reactivity: | human, mouse, rat, bovine, pig |
751.00€
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Item number: ABE-35-1173-100
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein,...
Keywords: | Anti-phospho-AMPK1, Anti-phospho-PRKAA1, Anti-phospho-HMGCR kinase, Anti-phospho-ACACA kinase, EC=2.7.11.26,... |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
682.00€
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