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Cay60401-1 5-​Lipoxygenase (potato) Screening Enzyme
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Contains purified potato 5-lipoxygenase (5-LO) supplied in 0.1 M Tris-HCl (pH 7.4) containing 0.1% BSA. 5-LO has been formulated to be used for screening 5-LO specific inhibitors using the Lipoxygenase Inhibitor Screening Assay (Catalog No. 760700).
Cayman
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1 each

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74 €

Cay10004161-100
CAS: 491-​70-​3
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.
MW: 286 D
Formula: C15H10O6
Purity: >98%
Cayman
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100 mg

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111 €

Cay10004161-50
CAS: 491-​70-​3
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.
MW: 286 D
Formula: C15H10O6
Purity: >98%
Cayman
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50 mg

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63 €

Cay10004161-500
CAS: 491-​70-​3
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Luteolin is one of the most potent flavanoid inhibitors of soybean and reticulocyte 15-lipoxygenases, with an IC50 of 0.6 µM.
MW: 286 D
Formula: C15H10O6
Purity: >98%
Cayman
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500 mg

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487 €

Cay10006967-10
CAS: 111406-​87-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
There is substantial evidence that the cysteinyl-​leukotrienes (cysLTs), such as LTC4, LTD4, and LTE4, play an important role in the pathophysiology of asthma. Arachidonic acid is the precursor fatty acid that is transformed into LTs by way of the 5-​lipoxy ... mehr
MW: 236 D
Formula: C11H12N2O2S
Purity: >98%
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10 mg

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35 €

Cay10006967-25
CAS: 111406-​87-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
There is substantial evidence that the cysteinyl-​leukotrienes (cysLTs), such as LTC4, LTD4, and LTE4, play an important role in the pathophysiology of asthma. Arachidonic acid is the precursor fatty acid that is transformed into LTs by way of the 5-​lipoxy ... mehr
MW: 236 D
Formula: C11H12N2O2S
Purity: >98%
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25 mg

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84 €

Cay10006967-5
CAS: 111406-​87-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
There is substantial evidence that the cysteinyl-​leukotrienes (cysLTs), such as LTC4, LTD4, and LTE4, play an important role in the pathophysiology of asthma. Arachidonic acid is the precursor fatty acid that is transformed into LTs by way of the 5-​lipoxy ... mehr
MW: 236 D
Formula: C11H12N2O2S
Purity: >98%
Cayman
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5 mg

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19 €

Cay10006967-50
CAS: 111406-​87-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
There is substantial evidence that the cysteinyl-​leukotrienes (cysLTs), such as LTC4, LTD4, and LTE4, play an important role in the pathophysiology of asthma. Arachidonic acid is the precursor fatty acid that is transformed into LTs by way of the 5-​lipoxy ... mehr
MW: 236 D
Formula: C11H12N2O2S
Purity: >98%
Cayman
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50 mg

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148 €

Cay10007692-1
CAS: 156897-​06-​2
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO) pathways, that decreases levels of prostaglandin E2, leukotriene B4, and lipoxins and prevents lipopolysaccharide-​stimulated IL-​1beta expression. The IC50 values for inhibition o ... mehr
MW: 379 D
Formula: C23H22ClNO2
Purity: >98%
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1 mg

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50 €

Cay10007692-10
CAS: 156897-​06-​2
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO) pathways, that decreases levels of prostaglandin E2, leukotriene B4, and lipoxins and prevents lipopolysaccharide-​stimulated IL-​1beta expression. The IC50 values for inhibition o ... mehr
MW: 379 D
Formula: C23H22ClNO2
Purity: >98%
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10 mg

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275 €

Cay10007692-5
CAS: 156897-​06-​2
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO) pathways, that decreases levels of prostaglandin E2, leukotriene B4, and lipoxins and prevents lipopolysaccharide-​stimulated IL-​1beta expression. The IC50 values for inhibition o ... mehr
MW: 379 D
Formula: C23H22ClNO2
Purity: >98%
Cayman
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5 mg

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150 €

Cay10007692-50
CAS: 156897-​06-​2
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Licofelone is a dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LO) pathways, that decreases levels of prostaglandin E2, leukotriene B4, and lipoxins and prevents lipopolysaccharide-​stimulated IL-​1beta expression. The IC50 values for inhibition o ... mehr
MW: 379 D
Formula: C23H22ClNO2
Purity: >98%
Cayman
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50 mg

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1247 €

Cay10007900-1
CAS: 34262-​64-​1
COX inhibitor, 12-​LO inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
8,11,14-Eicosatriynoic acid inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).
MW: 300 D
Formula: C20H28O2
Purity: >98%
Cayman
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1 mg

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77 €

Cay10007900-10
CAS: 34262-​64-​1
COX inhibitor, 12-​LO inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
8,11,14-Eicosatriynoic acid inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).
MW: 300 D
Formula: C20H28O2
Purity: >98%
Cayman
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10 mg

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612 €

Cay10007900-5
CAS: 34262-​64-​1
COX inhibitor, 12-​LO inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
8,11,14-Eicosatriynoic acid inhibits cyclooxygenase (IC50 = 14 µM), human 12-lipoxygenase (IC50 = 0.46 µM), 5-lipoxygenase (IC50 = 25 µM) and the actions of slow-reacting substance of anaphylaxis (SRS-A) (IC50 = 10 µM).
MW: 300 D
Formula: C20H28O2
Purity: >98%
Cayman
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5 mg

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345 €

Cay10010468-10
CAS: 928853-​86-​5
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-LO inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 µM. The inhibitor appears to act as an antioxidant, interfering with the redox cycle of 15-LO.
MW: 313 D
Formula: C16H19N5S
Purity: >98%
Cayman
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10 mg

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357 €

Cay10010468-5
CAS: 928853-​86-​5
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-LO inhibitor 1 is a heterocyclic pyrimidobenzothiazine compound that inhibits 15-LO with an IC50 value of 18 µM. The inhibitor appears to act as an antioxidant, interfering with the redox cycle of 15-LO.
MW: 313 D
Formula: C16H19N5S
Purity: >98%
Cayman
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5 mg

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204 €

Cay10010518-10
CAS: 4079-​26-​9
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1.
MW: 237 D
Formula: C15H11NS
Purity: >98%
Cayman
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10 mg

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84 €

Cay10010518-25
CAS: 4079-​26-​9
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1.
MW: 237 D
Formula: C15H11NS
Purity: >98%
Cayman
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25 mg

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198 €

Cay10010518-50
CAS: 4079-​26-​9
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
PD 146176 is a potent and selective inhibitor of reticulocyte 15-lipoxygenase-1.
MW: 237 D
Formula: C15H11NS
Purity: >98%
Cayman
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50 mg

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353 €

Cay13271-10
CAS: 1051931-​39-​5
COX inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
ZLJ-6 is a dual inhibitor of cyclooxygenase and 5-lipoxygenase . It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers.
MW: 375 D
Formula: C12H13N3O3S ? CH3SO3H
Purity: >98%
Cayman
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10 mg

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288 €

Cay13271-25
CAS: 1051931-​39-​5
COX inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
ZLJ-6 is a dual inhibitor of cyclooxygenase and 5-lipoxygenase . It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers.
MW: 375 D
Formula: C12H13N3O3S ? CH3SO3H
Purity: >98%
Cayman
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25 mg

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630 €

Cay13271-5
CAS: 1051931-​39-​5
COX inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
ZLJ-6 is a dual inhibitor of cyclooxygenase and 5-lipoxygenase . It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers.
MW: 375 D
Formula: C12H13N3O3S ? CH3SO3H
Purity: >98%
Cayman
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5 mg

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162 €

Cay13285-10
CAS: 1242-​67-​7
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CBDD is a cannabidiol derivative that potently and selectively inhibits 15-LO. It does not inhibit 5-LO effectively.
MW: 342 D
Formula: C23H34O2
Purity: >98%
Cayman
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10 mg

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232 €

Cay13285-5
CAS: 1242-​67-​7
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CBDD is a cannabidiol derivative that potently and selectively inhibits 15-LO. It does not inhibit 5-LO effectively.
MW: 342 D
Formula: C23H34O2
Purity: >98%
Cayman
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5 mg

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131 €

Cay13285-50
CAS: 1242-​67-​7
15-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CBDD is a cannabidiol derivative that potently and selectively inhibits 15-LO. It does not inhibit 5-LO effectively.
MW: 342 D
Formula: C23H34O2
Purity: >98%
Cayman
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50 mg

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1015 €

Cay13381-1
CAS: 1159576-​98-​3
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CAY10606 is a potent, reversible inhibitor of 5-​LO, both in cell-​free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-​LO is activated with the calcium ionophore A23187 (IC50 = 1 ... mehr
MW: 379 D
Formula: C22H18ClNO3
Purity: >98%
Cayman
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1 mg

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57 €

Cay13381-10
CAS: 1159576-​98-​3
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CAY10606 is a potent, reversible inhibitor of 5-​LO, both in cell-​free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-​LO is activated with the calcium ionophore A23187 (IC50 = 1 ... mehr
MW: 379 D
Formula: C22H18ClNO3
Purity: >98%
Cayman
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10 mg

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455 €

Cay13381-5
CAS: 1159576-​98-​3
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
CAY10606 is a potent, reversible inhibitor of 5-​LO, both in cell-​free assays (IC50 = 86 nM) and in intact neutrophils (IC50 = 230 nM). It prevents the production of LTs in whole blood, whether 5-​LO is activated with the calcium ionophore A23187 (IC50 = 1 ... mehr
MW: 379 D
Formula: C22H18ClNO3
Purity: >98%
Cayman
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5 mg

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256 €

Cay13665-1
CAS: 916482-​17-​2
mPGES-​1 / 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-​1 (mPGES-​1) (IC50 = 3.9 µM) and 5-​LO (IC50 = 4.1 µM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. Moreover, YS121 (1.5 kg/mg, intraperitoneal) re ... mehr
MW: 408 D
Formula: C20H26ClN3O2S
Purity: >98%
Cayman
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1 mg

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50 €

Cay13665-10
CAS: 916482-​17-​2
mPGES-​1 / 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-​1 (mPGES-​1) (IC50 = 3.9 µM) and 5-​LO (IC50 = 4.1 µM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. Moreover, YS121 (1.5 kg/mg, intraperitoneal) re ... mehr
MW: 408 D
Formula: C20H26ClN3O2S
Purity: >98%
Cayman
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10 mg

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399 €

Cay13665-25
CAS: 916482-​17-​2
mPGES-​1 / 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-​1 (mPGES-​1) (IC50 = 3.9 µM) and 5-​LO (IC50 = 4.1 µM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. Moreover, YS121 (1.5 kg/mg, intraperitoneal) re ... mehr
MW: 408 D
Formula: C20H26ClN3O2S
Purity: >98%
Cayman
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25 mg

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873 €

Cay13665-5
CAS: 916482-​17-​2
mPGES-​1 / 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-​1 (mPGES-​1) (IC50 = 3.9 µM) and 5-​LO (IC50 = 4.1 µM). It effectively inhibits PGE2 and LT synthesis in both cell free and intact cell assays. Moreover, YS121 (1.5 kg/mg, intraperitoneal) re ... mehr
MW: 408 D
Formula: C20H26ClN3O2S
Purity: >98%
Cayman
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5 mg

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225 €

Cay15483-1
neu

CAS: 1492060-​44-​2
mPGES-​1 & 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Microsomal prostaglandin E2 synthase-​1 (mPGES-​1) and 5-​lipoxygenase (5-​LO) are key enzymes in the synthesis of PGE2 (Item No. 14010) and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, i ... mehr
MW: 513 D
Formula: C25H25ClN4O2S
Purity: >98%
Cayman
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1 mg

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68 €

Cay15483-10
neu

CAS: 1492060-​44-​2
mPGES-​1 & 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Microsomal prostaglandin E2 synthase-​1 (mPGES-​1) and 5-​lipoxygenase (5-​LO) are key enzymes in the synthesis of PGE2 (Item No. 14010) and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, i ... mehr
MW: 513 D
Formula: C25H25ClN4O2S
Purity: >98%
Cayman
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10 mg

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493 €

Cay15483-25
neu

CAS: 1492060-​44-​2
mPGES-​1 & 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Microsomal prostaglandin E2 synthase-​1 (mPGES-​1) and 5-​lipoxygenase (5-​LO) are key enzymes in the synthesis of PGE2 (Item No. 14010) and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, i ... mehr
MW: 513 D
Formula: C25H25ClN4O2S
Purity: >98%
Cayman
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25 mg

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1078 €

Cay15483-5
neu

CAS: 1492060-​44-​2
mPGES-​1 & 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Microsomal prostaglandin E2 synthase-​1 (mPGES-​1) and 5-​lipoxygenase (5-​LO) are key enzymes in the synthesis of PGE2 (Item No. 14010) and leukotrienes (LTs), respectively. PGE2 and LTs are bioactive lipids that contribute to a broad range of pathologies, i ... mehr
MW: 513 D
Formula: C25H25ClN4O2S
Purity: >98%
Cayman
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5 mg

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291 €

Cay34215-0.05
CAS: 73279-​37-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM.
MW: 302 D
Formula: C20H30O2
Purity: >98%
Cayman
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50 µg

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78 €

Cay34215-0.1
CAS: 73279-​37-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM.
MW: 302 D
Formula: C20H30O2
Purity: >98%
Cayman
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100 µg

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146 €

Cay34215-0.5
CAS: 73279-​37-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
(±)5-HETE lactone is a cyclic ester formed by acid-catalyzed nucleophilic addition of the C-5 hydroxyl to the C-1 carboxyl of (±)5-HETE. It is an inhibitor of 5-lipoxygenase from rat basophilic leukemia cells with an IC50 of 27 µM.
MW: 302 D
Formula: C20H30O2
Purity: >98%
Cayman
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500 µg

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650 €

Cay36720-0.025
CAS: 92693-​02-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
MW: 322 D
Formula: C20H34O3
Purity: >98%
Cayman
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25 µg

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35 €

Cay36720-0.05
CAS: 92693-​02-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
MW: 322 D
Formula: C20H34O3
Purity: >98%
Cayman
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50 µg

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66 €

Cay36720-0.1
CAS: 92693-​02-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
MW: 322 D
Formula: C20H34O3
Purity: >98%
Cayman
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100 µg

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125 €

Cay36720-0.5
CAS: 92693-​02-​2
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HETrE is the hydroxy-trienoic acid resulting from 15-lipoxygenation of DGLA. It is an inhibitor of 5-LO in human PMNL with an IC50 value of 4.6 µM. In RBL cells, 15(S)-HETrE inhibits 5-LO, but is about 1/20 as potent as 15(S)-HpETE.
MW: 322 D
Formula: C20H34O3
Purity: >98%
Cayman
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500 µg

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557 €

Cay37720-0.05
CAS: 92693-​04-​4
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.
MW: 324 D
Formula: C20H36O3
Purity: >98%
Cayman
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50 µg

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201 €

Cay37720-0.1
CAS: 92693-​04-​4
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.
MW: 324 D
Formula: C20H36O3
Purity: >98%
Cayman
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100 µg

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380 €

Cay37720-0.25
CAS: 92693-​04-​4
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15(S)-HEDE is produced from 11Z,14Z-eicosadienoic acid by 15-LO. 15(S)-HEDE is an inhibitor of RBL-1 cell 5-LO with an IC50 value of 26 µM.
MW: 324 D
Formula: C20H36O3
Purity: >98%
Cayman
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250 µg

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844 €

Cay37730-0.025
CAS: 105835-​44-​7
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-​OxoEDE is produced by the oxidation of 15-​HEDE. 15-​OxoEDE inhibits 5-​LO from RBL-​1 cells with an IC50 of 55 µM, which is about 2-​fold lower than 15(S)-​HEDE. A related oxo-​eicosanoid, 5-​oxoETE, is biosynthesized from 5(S)-​HETE by a specific dehydrogenas ... mehr
MW: 322 D
Formula: C20H34O3
Purity: >95%
Cayman
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25 µg

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60 €

Cay37730-0.05
CAS: 105835-​44-​7
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-​OxoEDE is produced by the oxidation of 15-​HEDE. 15-​OxoEDE inhibits 5-​LO from RBL-​1 cells with an IC50 of 55 µM, which is about 2-​fold lower than 15(S)-​HEDE. A related oxo-​eicosanoid, 5-​oxoETE, is biosynthesized from 5(S)-​HETE by a specific dehydrogenas ... mehr
MW: 322 D
Formula: C20H34O3
Purity: >95%
Cayman
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50 µg

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115 €

Cay37730-0.1
CAS: 105835-​44-​7
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-​OxoEDE is produced by the oxidation of 15-​HEDE. 15-​OxoEDE inhibits 5-​LO from RBL-​1 cells with an IC50 of 55 µM, which is about 2-​fold lower than 15(S)-​HEDE. A related oxo-​eicosanoid, 5-​oxoETE, is biosynthesized from 5(S)-​HETE by a specific dehydrogenas ... mehr
MW: 322 D
Formula: C20H34O3
Purity: >95%
Cayman
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100 µg

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Cay37730-0.25
CAS: 105835-​44-​7
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
15-​OxoEDE is produced by the oxidation of 15-​HEDE. 15-​OxoEDE inhibits 5-​LO from RBL-​1 cells with an IC50 of 55 µM, which is about 2-​fold lower than 15(S)-​HEDE. A related oxo-​eicosanoid, 5-​oxoETE, is biosynthesized from 5(S)-​HETE by a specific dehydrogenas ... mehr
MW: 322 D
Formula: C20H34O3
Purity: >95%
Cayman
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250 µg

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483 €

Cay70300-1000
CAS: 500-​38-​9
LO inhibitor Erklärungen der Abkürzungen ansehen.
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis.
MW: 302 D
Formula: C18H22O4
Purity: >95%
Cayman
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1 g

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57 €

Cay70300-25000
CAS: 500-​38-​9
LO inhibitor Erklärungen der Abkürzungen ansehen.
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis.
MW: 302 D
Formula: C18H22O4
Purity: >95%
Cayman
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25 g

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422 €

Cay70300-500
CAS: 500-​38-​9
LO inhibitor Erklärungen der Abkürzungen ansehen.
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis.
MW: 302 D
Formula: C18H22O4
Purity: >95%
Cayman
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500 mg

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30 €

Cay70300-5000
CAS: 500-​38-​9
LO inhibitor Erklärungen der Abkürzungen ansehen.
NDGA is a non-selective lipoxygenase (LO) inhibitor which blocks cysteinyl leukotriene (CysLT) synthesis.
MW: 302 D
Formula: C18H22O4
Purity: >95%
Cayman
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5 g

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241 €

Cay70302-1
CAS: 24150-​24-​1
LO inhibitor Erklärungen der Abkürzungen ansehen.
Tetramethyl Nordihydroguaiaretic acid (TMNDGA) is a synthetic derivative of NDGA, a non-selective lipoxygenase inhibitor. It induces growth arrest and apoptosis by suppressing Sp1-dependent Cdc2 and survivin gene expression.
MW: 358 D
Formula: C22H3O4
Purity: >95%
Cayman
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1 g

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179 €

Cay70302-500
CAS: 24150-​24-​1
LO inhibitor Erklärungen der Abkürzungen ansehen.
Tetramethyl Nordihydroguaiaretic acid (TMNDGA) is a synthetic derivative of NDGA, a non-selective lipoxygenase inhibitor. It induces growth arrest and apoptosis by suppressing Sp1-dependent Cdc2 and survivin gene expression.
MW: 358 D
Formula: C22H3O4
Purity: >95%
Cayman
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500 mg

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102 €

Cay70530-10
CAS: 60940-​34-​3
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase and lipoxygenases at micromolar concentrations.
MW: 274 D
Formula: C13H9NOSe
Purity: >99%
Cayman
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10 mg

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39 €

Cay70530-100
CAS: 60940-​34-​3
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase and lipoxygenases at micromolar concentrations.
MW: 274 D
Formula: C13H9NOSe
Purity: >99%
Cayman
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100 mg

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292 €

Cay70530-5
CAS: 60940-​34-​3
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase and lipoxygenases at micromolar concentrations.
MW: 274 D
Formula: C13H9NOSe
Purity: >99%
Cayman
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5 mg

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21 €

Cay70530-50
CAS: 60940-​34-​3
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
The glutathione peroxidase-like activity of ebselen inhibits cyclooxygenase and lipoxygenases at micromolar concentrations.
MW: 274 D
Formula: C13H9NOSe
Purity: >99%
Cayman
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50 mg

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167 €

Cay70600-10
CAS: 101910-​24-​1
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.
MW: 335 D
Formula: C22H25NO2
Purity: >98%
Cayman
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10 mg

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56 €

Cay70600-100
CAS: 101910-​24-​1
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.
MW: 335 D
Formula: C22H25NO2
Purity: >98%
Cayman
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100 mg

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406 €

Cay70600-5
CAS: 101910-​24-​1
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.
MW: 335 D
Formula: C22H25NO2
Purity: >98%
Cayman
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5 mg

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29 €

Cay70600-50
CAS: 101910-​24-​1
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
REV 5901 is an antagonist of cysteinyl-leukotriene receptors with a Ki value of 0.7 µM for guinea pig lung membranes. It is also an inhibitor of rat neutrophil 5-LO with an IC50 value of 0.12 µM.
MW: 335 D
Formula: C22H25NO2
Purity: >98%
Cayman
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50 mg

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232 €

Cay70602-10
CAS: 331-​39-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Caffeic acid is an inhibitor of 5-LO with an IC50 value of 3.7-72 µM and 12-LO with an IC50 value of 5.1-30 µM.
MW: 180 D
Formula: C9H8O4
Purity: >97%
Cayman
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10 g

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60 €

Cay70602-25
CAS: 331-​39-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Caffeic acid is an inhibitor of 5-LO with an IC50 value of 3.7-72 µM and 12-LO with an IC50 value of 5.1-30 µM.
MW: 180 D
Formula: C9H8O4
Purity: >97%
Cayman
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25 g

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104 €

Cay70602-5
CAS: 331-​39-​5
5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
Caffeic acid is an inhibitor of 5-LO with an IC50 value of 3.7-72 µM and 12-LO with an IC50 value of 5.1-30 µM.
MW: 180 D
Formula: C9H8O4
Purity: >97%
Cayman
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5 g

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38 €

Cay70635-10
CAS: 443919-​96-​8
COX-​2 inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
COX-2/5-LO inhibitors such as CAY10416 are apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy.
MW: 536 D
Formula: C29H29FN2O5S
Purity: >95%
Cayman
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10 mg

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418 €

Cay70635-5
CAS: 443919-​96-​8
COX-​2 inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
COX-2/5-LO inhibitors such as CAY10416 are apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy.
MW: 536 D
Formula: C29H29FN2O5S
Purity: >95%
Cayman
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5 mg

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235 €

Cay760700-96 Lipoxygenase Inhibitor Screening Assay Kit
LO inhibitor screening Erklärungen der Abkürzungen ansehen.
Cayman's Lipoxygenase Inhibitor Screening Assay Kit detects and measures the hydroperoxides produced in the lipoxygenation reaction using a purified LO. The detection reaction is equally sensitive to hydroperoxides at various positions within the fatty ac ... mehr
Cayman
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96 wells

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205 €

Cay90200-1
CAS: 13488-​22-​7
LO inhibitor Erklärungen der Abkürzungen ansehen.
5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.
MW: 300 D
Formula: C20H28O2
Purity: >99%
Cayman
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1 mg

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77 €

Cay90200-10
CAS: 13488-​22-​7
LO inhibitor Erklärungen der Abkürzungen ansehen.
5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.
MW: 300 D
Formula: C20H28O2
Purity: >99%
Cayman
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10 mg

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612 €

Cay90200-5
CAS: 13488-​22-​7
LO inhibitor Erklärungen der Abkürzungen ansehen.
5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM.
MW: 300 D
Formula: C20H28O2
Purity: >99%
Cayman
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5 mg

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345 €

Cay90400-1
CAS: 2012-​14-​8
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Ro 3-1314 is an inhibitor of both COX and lipoxygenase. Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 µM.{1260} It is a more effective inhibitor of COX-1 than of 15-LO.
MW: 276 D
Formula: C18H28O2
Purity: >98%
Cayman
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1 mg

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71 €

Cay90400-10
CAS: 2012-​14-​8
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Ro 3-1314 is an inhibitor of both COX and lipoxygenase. Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 µM.{1260} It is a more effective inhibitor of COX-1 than of 15-LO.
MW: 276 D
Formula: C18H28O2
Purity: >98%
Cayman
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10 mg

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566 €

Cay90400-5
CAS: 2012-​14-​8
COX inhibitor, LO inhibitor Erklärungen der Abkürzungen ansehen.
Ro 3-1314 is an inhibitor of both COX and lipoxygenase. Ro 3-1314 inhibits ram seminal vesicle COX with a Ki of 0.6 µM.{1260} It is a more effective inhibitor of COX-1 than of 15-LO.
MW: 276 D
Formula: C18H28O2
Purity: >98%
Cayman
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5 mg

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319 €



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