| 476 Treffer |
| ART-NR | PRODUKT | HERSTELLER | MENGE | PREIS |
| A1124-20B.1 |
Akt Inhibitor, Isozyme-selective (1,3-Dihydro-1-(1-((4-(6-phenyl-1H-imidazo[4,5-g]quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one, Akti-1/2) CAS: 612847-09-3 Purity: ~97% (HPLC) |
USBio |
1 mg |
325 €
 |
| AG-CN2-0019-C100 |
CAS: 97161-97-2 Tyrosine kinase inhibitor  Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK ... mehr MW: 467 D Formula: C27H21N3O5 Purity: >98% |
Adipogen |
100 µg |
108 €
|
| AG-CN2-0019-M001 |
CAS: 97161-97-2 Tyrosine kinase inhibitor Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK ... mehr MW: 467 D Formula: C27H21N3O5 Purity: >98% |
Adipogen |
1 mg |
495 €
|
| AG-CN2-0022-C100 |
CAS: 62996-74-1 Protein kinase inhibitor, Apoptosis inducer Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
Adipogen |
100 µg |
50 €
|
| AG-CN2-0022-C500 |
CAS: 62996-74-1 Protein kinase inhibitor, Apoptosis inducer Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
Adipogen |
500 µg |
105 €
|
| AG-CN2-0022-M001 |
CAS: 62996-74-1 Protein kinase inhibitor, Apoptosis inducer Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
Adipogen |
1 mg |
143 €
|
| AG-CN2-0022-M005 |
CAS: 62996-74-1 Protein kinase inhibitor, Apoptosis inducer Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-induced platelet aggregation. Potent, cell permeable, reversible, ATP-competitive and ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
Adipogen |
5 mg |
418 €
|
| AG-CN2-0056-C025 |
CAS: 78111-17-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 805 D Formula: C44H68O13 Purity: >98% |
Adipogen |
25 µg |
77 €
|
| AG-CN2-0056-C100 |
CAS: 78111-17-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 805 D Formula: C44H68O13 Purity: >98% |
Adipogen |
100 µg |
187 €
|
| AG-CN2-0056-M001 |
CAS: 78111-17-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 805 D Formula: C44H68O13 Purity: >98% |
Adipogen |
1 mg |
1320 €
|
| AG-CN2-0057-C010 |
CAS: 87860-39-7 Ser / Thr phosphatase inhibitor Antibiotic. Anticancer compound. Anti-fungal. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM). Potent protein phosphatase 2A (PP2A) (IC50 = 1. 5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM) ... mehr MW: 452 D Formula: C19H26O9PNa Purity: >98% |
Adipogen |
10 µg |
198 €
|
| AG-CN2-0058-C025 |
CAS: 155716-06-6 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful ... mehr MW: 822 D Formula: C44H67O13-NH4 Purity: >98% |
Adipogen |
25 µg |
83 €
|
| AG-CN2-0058-C100 |
CAS: 155716-06-6 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful ... mehr MW: 822 D Formula: C44H67O13-NH4 Purity: >98% |
Adipogen |
100 µg |
198 €
|
| AG-CN2-0058-M001 |
CAS: 155716-06-6 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful ... mehr MW: 822 D Formula: C44H67O13-NH4 Purity: >98% |
Adipogen |
1 mg |
1430 €
|
| AG-CN2-0060-C025 |
CAS: 155751-72-7 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 843 D Formula: C44H67O13-K Purity: >98% |
Adipogen |
25 µg |
83 €
|
| AG-CN2-0060-C100 |
CAS: 155751-72-7 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 843 D Formula: C44H67O13-K Purity: >98% |
Adipogen |
100 µg |
198 €
|
| AG-CN2-0060-M001 |
CAS: 155751-72-7 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 843 D Formula: C44H67O13-K Purity: >98% |
Adipogen |
1 mg |
1430 €
|
| AG-CN2-0062-C025 |
CAS: 209266-80-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 827 D Formula: C44H67O13-Na Purity: >98% |
Adipogen |
25 µg |
83 €
|
| AG-CN2-0062-C100 |
CAS: 209266-80-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 827 D Formula: C44H67O13-Na Purity: >98% |
Adipogen |
100 µg |
198 €
|
| AG-CN2-0062-M001 |
CAS: 209266-80-8 Ser / Thr phosphatase inhibitor Non-phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-1nM), PP1 (IC50=3-15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr MW: 827 D Formula: C44H67O13-Na Purity: >98% |
Adipogen |
1 mg |
1430 €
|
| AG-CN2-0068-C100 |
CAS: 75593-17-8 PKC Inhibitor Protein kinase C (PKC) inhibitor. Inhibits the ATP binding site. Cytotoxic and insecticidal. G2 DNA damage checkpoint inhibitor. Check point kinases 1 (Chk1) and 2 (Chk2) inhibitor. Does not inhibit ataxia-telangiectasia mutated (ATM) or ATM-Rad3-related ... mehr MW: 245 D Formula: C11H11N5O2 Purity: >95% |
Adipogen |
100 µg |
110 €
|
| AG-CN2-0111-M001 |
CAS: 35082-49-6 PKC Inhibitor Phytotoxin - Potent and specific PKC inhibitor. Competes for the phorbol binding site - Anticancer compound. Cytotoxic - Antiproliferative - Antiparasitic - Antimicrobial. MW: 534 D Formula: C29H26O10 Purity: >95% |
Adipogen |
1 mg |
55 €
|
| AG-CN2-0111-M005 |
CAS: 35082-49-6 PKC Inhibitor Phytotoxin - Potent and specific PKC inhibitor. Competes for the phorbol binding site - Anticancer compound. Cytotoxic - Antiproliferative - Antiparasitic - Antimicrobial. MW: 534 D Formula: C29H26O10 Purity: >95% |
Adipogen |
5 mg |
220 €
|
| AG-CR1-0001-M010 |
CAS: 113276-94-1 PKA / PKG inhibitor, MLCK inhibitor Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Myosin light chain kinase (MLCK) inhibitor, Tool to study protein crystal structure-inhibitor interactions. MW: 265 D Formula: C12H15N3O2S . 2HCl Purity: >98% |
Adipogen |
10 mg |
44 €
|
| AG-CR1-0001-M050 |
CAS: 113276-94-1 PKA / PKG inhibitor, MLCK inhibitor Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Myosin light chain kinase (MLCK) inhibitor, Tool to study protein crystal structure-inhibitor interactions. MW: 265 D Formula: C12H15N3O2S . 2HCl Purity: >98% |
Adipogen |
50 mg |
176 €
|
| AG-CR1-0002-M001 |
CAS: 127243-85-0 PKA / PKG inhibitor, PKC inhibitor Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) ... mehr MW: 446 D Formula: C20H20BrN3O2S . 2HCl Purity: >98% |
Adipogen |
1 mg |
28 €
|
| AG-CR1-0002-M005 |
CAS: 127243-85-0 PKA / PKG inhibitor, PKC inhibitor Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) ... mehr MW: 446 D Formula: C20H20BrN3O2S . 2HCl Purity: >98% |
Adipogen |
5 mg |
55 €
|
| AG-CR1-0002-M025 |
CAS: 127243-85-0 PKA / PKG inhibitor, PKC inhibitor Cell permeable potent and selective cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) ... mehr MW: 446 D Formula: C20H20BrN3O2S . 2HCl Purity: >98% |
Adipogen |
25 mg |
220 €
|
| AG-CR1-0006-M001 |
CAS: 186692-46-6 CDK inhibitor Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr MW: 354 D Formula: C19H26N6O Purity: >98% |
Adipogen |
1 mg |
33 €
|
| AG-CR1-0006-M005 |
CAS: 186692-46-6 CDK inhibitor Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr MW: 354 D Formula: C19H26N6O Purity: >98% |
Adipogen |
5 mg |
99 €
|
| AG-CR1-0006-M050 |
CAS: 186692-46-6 CDK inhibitor Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr MW: 354 D Formula: C19H26N6O Purity: >98% |
Adipogen |
50 mg |
297 €
|
| AG-CR1-0009-M001 |
CAS: 133052-90-1 PKC inhibitor Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-binding site of PKC, Anti-inflammatory, Binds to P-glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase k ... mehr MW: 412 D Formula: C25H24N4O2 Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0009-M005 |
CAS: 133052-90-1 PKC inhibitor Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-binding site of PKC, Anti-inflammatory, Binds to P-glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase k ... mehr MW: 412 D Formula: C25H24N4O2 Purity: >98% |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0010-M001 |
Bisindolylmaleimide II PKC inhibitor Protein kinase C (PKC) inhibitor, Binds with reversed orientation to protein kinase A (PKA). MW: 438 D Formula: C27H26N4O2 Purity: >97% (mixture of 2 isomer |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0010-M005 |
Bisindolylmaleimide II PKC inhibitor Protein kinase C (PKC) inhibitor, Binds with reversed orientation to protein kinase A (PKA). MW: 438 D Formula: C27H26N4O2 Purity: >97% (mixture of 2 isomer |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0025-M001 |
CAS: 284461-73-0 Raf kinase inhibitor Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review. MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0025-M005 |
CAS: 284461-73-0 Raf kinase inhibitor Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review. MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Adipogen |
5 mg |
242 €
|
| AG-CR1-0025-M025 |
CAS: 284461-73-0 Raf kinase inhibitor Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review. MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Adipogen |
25 mg |
726 €
|
| AG-CR1-0028-M001 |
CAS: 152121-30-7 p38 MAP kinase inhibitor Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator. MW: 331 D Formula: C20H14FN3O Purity: >97% |
Adipogen |
1 mg |
36 €
|
| AG-CR1-0028-M005 |
CAS: 152121-30-7 p38 MAP kinase inhibitor Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator. MW: 331 D Formula: C20H14FN3O Purity: >97% |
Adipogen |
5 mg |
88 €
|
| AG-CR1-0028-M025 |
CAS: 152121-30-7 p38 MAP kinase inhibitor Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator. MW: 331 D Formula: C20H14FN3O Purity: >97% |
Adipogen |
25 mg |
341 €
|
| AG-CR1-0029-M001 |
CAS: 212631-79-3 MEK inhibitor MEK (MAPKK) inhibitor, Potent and selective MAPK (ERK kinase 1, MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo), Suppresses activation of MAPK but does not block its activity, Antiproliferative, Causes cell-cycle arrest in G1 phas ... mehr MW: 478 D Formula: C17H14ClF2IN2O2 Purity: >95% |
Adipogen |
1 mg |
28 €
|
| AG-CR1-0029-M005 |
CAS: 212631-79-3 MEK inhibitor MEK (MAPKK) inhibitor, Potent and selective MAPK (ERK kinase 1, MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo), Suppresses activation of MAPK but does not block its activity, Antiproliferative, Causes cell-cycle arrest in G1 phas ... mehr MW: 478 D Formula: C17H14ClF2IN2O2 Purity: >95% |
Adipogen |
5 mg |
99 €
|
| AG-CR1-0030-M001 |
CAS: 152121-47-6 p38 MAP kinase inhibitor Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferati ... mehr MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Adipogen |
1 mg |
39 €
|
| AG-CR1-0030-M005 |
CAS: 152121-47-6 p38 MAP kinase inhibitor Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferati ... mehr MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Adipogen |
5 mg |
105 €
|
| AG-CR1-0030-M025 |
CAS: 152121-47-6 p38 MAP kinase inhibitor Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-2 production inhibitor, SAPK/JNK inhibitor, COX-1 and -2 inhibitor, Raf-1 activator, Apoptosis enhancer, Antiproliferati ... mehr MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Adipogen |
25 mg |
418 €
|
| AG-CR1-0035-M001 |
CAS: 676596-65-9 GSK-3beta inhibitor Potent and ATP-competitive GSK-3beta (glycogen synthase kinase-3beta) inhibitor (IC50 = 18 nM). MW: 328 D Formula: C15H10BrN3O Purity: >98% |
Adipogen |
1 mg |
88 €
|
| AG-CR1-0035-M005 |
CAS: 676596-65-9 GSK-3beta inhibitor Potent and ATP-competitive GSK-3beta (glycogen synthase kinase-3beta) inhibitor (IC50 = 18 nM). MW: 328 D Formula: C15H10BrN3O Purity: >98% |
Adipogen |
5 mg |
352 €
|
| AG-CR1-0036-M001 |
CAS: 237430-03-4 CDK inhibitor Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-3beta (glycogen synthase kinase-3beta) inhibitor, Apoptosis inhibito ... mehr MW: 293 D Formula: C16H11N3O3 Purity: >98% |
Adipogen |
1 mg |
77 €
|
| AG-CR1-0036-M005 |
CAS: 237430-03-4 CDK inhibitor Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-3beta (glycogen synthase kinase-3beta) inhibitor, Apoptosis inhibito ... mehr MW: 293 D Formula: C16H11N3O3 Purity: >98% |
Adipogen |
5 mg |
308 €
|
| AG-CR1-0039-M001 |
CAS: 294646-77-8 CDK inhibitor Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor. MW: 431 D Formula: C24H29N7O Purity: >98% |
Adipogen |
1 mg |
50 €
|
| AG-CR1-0039-M005 |
CAS: 294646-77-8 CDK inhibitor Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor. MW: 431 D Formula: C24H29N7O Purity: 98% |
Adipogen |
5 mg |
143 €
|
| AG-CR1-0040-M001 |
CAS: 294646-77-8 CDK inhibitor Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Glycogen synthase kinase (GSK-3alpha/beta) inhibitor. MW: 431 D Formula: C24H29N7O Purity: >98% |
Adipogen |
1 mg |
50 €
|
| AG-CR1-0040-M005 |
CAS: 294646-77-8 CDK inhibitor Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Glycogen synthase kinase (GSK-3alpha/beta) inhibitor. MW: 431 D Formula: C24H29N7O Purity: >98% |
Adipogen |
5 mg |
143 €
|
| AG-CR1-0049-M005 |
CAS: 337349-54-9 Necroptosis inhibitor Necroptosis inhibitor, Indirect RIP1 kinase inhibitor. MW: 383 D Formula: C19H17N3O2S2 Purity: >98% |
Adipogen |
5 mg |
44 €
|
| AG-CR1-0049-M025 |
CAS: 337349-54-9 Necroptosis inhibitor Necroptosis inhibitor, Indirect RIP1 kinase inhibitor. MW: 383 D Formula: C19H17N3O2S2 Purity: >98% |
Adipogen |
25 mg |
176 €
|
| AG-CR1-0065-M001 |
Ca2 dependent protein kinase II inhibitor Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor. MW: 501 D Formula: C26H29ClN2O4S . H3PO4 Purity: >98% |
Adipogen |
1 mg |
94 €
|
| AG-CR1-0065-M005 |
Ca2 dependent protein kinase II inhibitor Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor. MW: 501 D Formula: C26H29ClN2O4S . H3PO4 Purity: >98% |
Adipogen |
5 mg |
319 €
|
| AG-CR1-0065-M025 |
Ca2 dependent protein kinase II inhibitor Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor. MW: 501 D Formula: C26H29ClN2O4S . H3PO4 Purity: >98% |
Adipogen |
25 mg |
798 €
|
| AG-CR1-0071-M001 |
CAS: 3895-92-9 PKC inhibitor Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase, antiplatelet, anti-inflammatory, antibacterial and antitumor compound, apoptosis ... mehr MW: 383 D Formula: C21H18ClNO Purity: >98% |
Adipogen |
1 mg |
33 €
|
| AG-CR1-0071-M005 |
CAS: 3895-92-9 PKC inhibitor Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase, antiplatelet, anti-inflammatory, antibacterial and antitumor compound, apoptosis ... mehr MW: 383 D Formula: C21H18ClNO Purity: >98% |
Adipogen |
5 mg |
72 €
|
| AG-CR1-0071-M025 |
CAS: 3895-92-9 PKC inhibitor Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase or calcium/calmodulin-dependent protein kinase, antiplatelet, anti-inflammatory, antibacterial and antitumor compound, apoptosis ... mehr MW: 383 D Formula: C21H18ClNO Purity: >98% |
Adipogen |
25 mg |
286 €
|
| AG-CR1-0087-M001 |
CAS: 169939-93-9 PKCbeta inhibitor Isozyme selective inhibitor of protein kinase Cb eta (PKCbeta) - PKCbeta-I and PKCbeta-II isozyme inhibitor - Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy - Anti-cancer and anti-angiogenic compound - Suppresse ... mehr MW: 505 D Formula: C28H28N4O3-HCl Purity: >98% |
Adipogen |
1 mg |
99 €
|
| AG-CR1-0087-M005 |
CAS: 169939-93-9 PKCbeta inhibitor Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta) - PKCbeta-I and PKCbeta-II isozyme inhibitor - Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy - Anti-cancer and anti-angiogenic compound - Suppresses ... mehr MW: 505 D Formula: C28H28N4O3-HCl Purity: >98% |
Adipogen |
5 mg |
308 €
|
| AG-CR1-0109-M001 |
CAS: 151342-35-7 PKC inhibitor Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo. Formula: C28H28N4O2 . HCl Purity: >98% |
Adipogen |
1 mg |
88 €
|
| AG-CR1-0109-M005 |
CAS: 151342-35-7 PKC inhibitor Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo. Formula: C28H28N4O2 . HCl Purity: >98% |
Adipogen |
5 mg |
286 €
|
| AG-CR1-0110-M001 |
CAS: 176504-36-2 PKC inhibitor Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki= 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase ki ... mehr Formula: C25H24N4O2 . HCl |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0110-M005 |
CAS: 176504-36-2 PKC inhibitor Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki= 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase ki ... mehr Formula: C25H24N4O2 . HCl |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0111-M001 |
CAS: 138489-18-6 PKC inhibitor Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces T ... mehr Formula: C25H23N5O2S . CH4O3S Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0111-M005 |
CAS: 138489-18-6 PKC inhibitor Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces T ... mehr Formula: C25H23N5O2S . CH4O3S Purity: >98% |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0112-M001 |
PKC inhibitor Potent and selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). MW: 384 D Formula: C23H20N4O2 Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0112-M005 |
PKC inhibitor Potent and selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). MW: 384 D Formula: C23H20N4O2 Purity: >98% |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0113-M001 |
CAS: 131848-97-0 PKC inhibitor Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils. Formula: C26H24N4O2 . HCl Purity: >98% |
Adipogen |
1 mg |
88 €
|
| AG-CR1-0113-M005 |
CAS: 131848-97-0 PKC inhibitor Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils. Formula: C26H24N4O2 . HCl Purity: >98% |
Adipogen |
5 mg |
286 €
|
| AG-CR1-0114-M001 |
CAS: 138516-31-1 PKC inhibitor Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. I ... mehr Formula: C24H22N4O2 . CH3COOH Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0114-M005 |
CAS: 138516-31-1 PKC inhibitor Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas- and TRAIL-mediated apoptosis. Inhibits T cell-mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. I ... mehr Formula: C24H22N4O2 . CH3COOH Purity: >98% |
Adipogen |
5 mg |
182 €
|
| AG-CR1-0152-M001 |
CAS: 119139-23-0 PKC / PKA inhibitor Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA). MW: 327 D Formula: C20H13N3O2 Purity: >98% |
Adipogen |
1 mg |
61 €
|
| AG-CR1-0152-M005 |
CAS: 119139-23-0 PKC / PKA inhibitor Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA). MW: 327 D Formula: C20H13N3O2 Purity: >98% |
Adipogen |
5 mg |
182 €
|
| AG-CR1-3503-M005 |
CAS: 327033-36-3 Pim-1 / Pim-2 kinase inhibitor Selective inhibitor of Pim-1 and Pim-2 protein kinases, Inducer of G1 phase cell cycle arrest, Inducer of p27Kip1, Inducer of apoptosis through the mitochondrial pathway, Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway, Downregulates c- ... mehr MW: 273 D Formula: C11H6F3NO2S Purity: >95% |
Adipogen |
5 mg |
88 €
|
| AG-CR1-3564-M001 |
CAS: 146986-50-7 ROCK kinase inhibitor Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr Formula: C14H21N3O - 2HCl Purity: >98% |
Adipogen |
1 mg |
72 €
|
| AG-CR1-3564-M005 |
CAS: 146986-50-7 ROCK kinase inhibitor Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr Formula: C14H21N3O - 2HCl Purity: >98% |
Adipogen |
5 mg |
286 €
|
| AG-CR1-3564-M025 |
CAS: 146986-50-7 ROCK kinase inhibitor Potent, cell permeable, selective and ATP-competitive Rho-associated protein kinases inhibitor, including p160ROCK, ROCK-II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr Formula: C14H21N3O - 2HCl Purity: >98% |
Adipogen |
25 mg |
858 €
|
| AG-CR1-3575-G001 |
CAS: 129-46-4 ATPase Inhibitor Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-specific growth factors ... mehr MW: 1.429 D Formula: C51H34N6O23S6-6Na Purity: >98% |
Adipogen |
1 g |
396 €
|
| AG-CR1-3575-M050 |
CAS: 129-46-4 ATPase Inhibitor Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-specific growth factors ... mehr MW: 1.429 D Formula: C51H34N6O23S6-6Na Purity: >98% |
Adipogen |
50 mg |
44 €
|
| AG-CR1-3575-M250 |
CAS: 129-46-4 ATPase Inhibitor Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-specific growth factors ... mehr MW: 1.429 D Formula: C51H34N6O23S6-6Na Purity: >98% |
Adipogen |
250 mg |
176 €
|
| AG-CR1-3577-M005 |
CAS: 918505-84-7 B-Raf ( V600E ) / c-Raf-1 ( Y340D / Y341D ) inhibitor Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. MW: 413 D Formula: C17H14ClF2N3O3S |
Adipogen |
5 mg |
121 €
|
| AG-CR1-3577-M025 |
CAS: 918505-84-7 B-Raf ( V600E ) / c-Raf-1 ( Y340D / Y341D ) inhibitor Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. MW: 413 D Formula: C17H14ClF2N3O3S |
Adipogen |
25 mg |
363 €
|
| Cay10005583-10 |
CAS: 129830-38-2 ROCK inhibitor Y-27632 is a potent, ATP-competitive inhibitor of Rho-associated protein kinases including p160ROCK (Ki = 140 nM) and ROCK-II (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM. MW: 320 D Formula: C14H21N3O · 2HCl Purity: >98% |
Cayman |
10 mg |
499 €
|
| Cay10005583-5 |
CAS: 129830-38-2 ROCK inhibitor Y-27632 is a potent, ATP-competitive inhibitor of Rho-associated protein kinases including p160ROCK (Ki = 140 nM) and ROCK-II (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM. MW: 320 D Formula: C14H21N3O · 2HCl Purity: >98% |
Cayman |
5 mg |
288 €
|
| Cay10006727-1 |
CAS: 152121-53-4 p38 MAPK inhibitor PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK) and >1,000-fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr MW: 360 D Formula: C20H13FN4O2 Purity: >98% |
Cayman |
1 mg |
81 €
|
| Cay10006727-10 |
CAS: 152121-53-4 p38 MAPK inhibitor PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK) and >1,000-fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr MW: 360 D Formula: C20H13FN4O2 Purity: >98% |
Cayman |
10 mg |
487 €
|
| Cay10006727-25 |
CAS: 152121-53-4 p38 MAPK inhibitor PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK) and >1,000-fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr MW: 360 D Formula: C20H13FN4O2 Purity: >98% |
Cayman |
25 mg |
914 €
|
| Cay10006727-5 |
CAS: 152121-53-4 p38 MAPK inhibitor PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-fold higher for extracellular signal-regulated kinase (ERK) and >1,000-fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr MW: 360 D Formula: C20H13FN4O2 Purity: >98% |
Cayman |
5 mg |
299 €
|
| Cay10007784-1 |
Akt inhibitor, PKB inhibitor Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphata ... mehr MW: 690 D Formula: C6H12O21P5 . 5Na Purity: >98% |
Cayman |
1 mg |
455 €
|
| Cay10007784-100 |
Akt inhibitor, PKB inhibitor Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphata ... mehr MW: 690 D Formula: C6H12O21P5 . 5Na Purity: >98% |
Cayman |
100 µg |
57 €
|
| Cay10007784-5 |
Akt inhibitor, PKB inhibitor Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphata ... mehr MW: 690 D Formula: C6H12O21P5 . 5Na Purity: >98% |
Cayman |
5 mg |
1989 €
|
| Cay10007784-500 |
Akt inhibitor, PKB inhibitor Inositol-1,3,4,5,6-pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-kinase/1-phosphata ... mehr MW: 690 D Formula: C6H12O21P5 . 5Na Purity: >98% |
Cayman |
500 µg |
256 €
|
| Cay10009569-10 |
CAS: 186692-46-6 CDK inhibitor, cyclin inhibitor (R)-Roscovitine is a potent inhibitor of CDK2/cyclin E with an IC50 value of 0.1 µM. It also inhibits CDK7/cyclin H, CDK5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively. MW: 354 D Formula: C19H26N6O Purity: >98% |
Cayman |
10 mg |
276 €
|
| Cay10009569-5 |
CAS: 186692-46-6 CDK inhibitor, cyclin inhibitor (R)-Roscovitine is a potent inhibitor of CDK2/cyclin E with an IC50 value of 0.1 µM. It also inhibits CDK7/cyclin H, CDK5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively. MW: 354 D Formula: C19H26N6O Purity: >98% |
Cayman |
5 mg |
158 €
|
| Cay10009644-1 |
CAS: 284461-73-0 Kinase inhibitor The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-9006 is an inhibitor of Raf-1 and B-Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Cayman |
1 mg |
32 €
|
| Cay10009644-10 |
CAS: 284461-73-0 Kinase inhibitor The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-9006 is an inhibitor of Raf-1 and B-Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Cayman |
10 mg |
77 €
|
| Cay10009644-5 |
CAS: 284461-73-0 Kinase inhibitor The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-9006 is an inhibitor of Raf-1 and B-Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Cayman |
5 mg |
51 €
|
| Cay10009644-50 |
CAS: 284461-73-0 Kinase inhibitor The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-9006 is an inhibitor of Raf-1 and B-Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr MW: 464 D Formula: C21H16ClF3N4O3 Purity: >98% |
Cayman |
50 mg |
299 €
|
| Cay10010043-10 |
CAS: 933786-58-4 ERK2 inhibitor CAY10561 is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM). MW: 459 D Formula: C22H17Cl2FN4O2 Purity: >98% |
Cayman |
10 mg |
325 €
|
| Cay10010043-5 |
CAS: 933786-58-4 ERK2 inhibitor CAY10561 is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM). MW: 459 D Formula: C22H17Cl2FN4O2 Purity: >98% |
Cayman |
5 mg |
186 €
|
| Cay10010233-1 |
CAS: 32387-96-5 Akt1 translocation inhibitor CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain. MW: 326 D Formula: C21H14N2O2 Purity: >98% |
Cayman |
1 g |
186 €
|
| Cay10010233-100 |
CAS: 32387-96-5 Akt1 translocation inhibitor CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain. MW: 326 D Formula: C21H14N2O2 Purity: >98% |
Cayman |
100 mg |
24 €
|
| Cay10010233-250 |
CAS: 32387-96-5 Akt1 translocation inhibitor CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain. MW: 326 D Formula: C21H14N2O2 Purity: >98% |
Cayman |
250 mg |
58 €
|
| Cay10010233-500 |
CAS: 32387-96-5 Akt1 translocation inhibitor CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain. MW: 326 D Formula: C21H14N2O2 Purity: >98% |
Cayman |
500 mg |
110 €
|
| Cay10010236-100 |
CAS: 105637-50-1 Ser / Thr kinase inhibitor ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase. MW: 361 D Formula: C15H17ClN2O2S · HCl Purity: >98% |
Cayman |
100 mg |
313 €
|
| Cay10010236-250 |
CAS: 105637-50-1 Ser / Thr kinase inhibitor ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase. MW: 361 D Formula: C15H17ClN2O2S · HCl Purity: >98% |
Cayman |
250 mg |
587 €
|
| Cay10010236-50 |
CAS: 105637-50-1 Ser / Thr kinase inhibitor ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase. MW: 361 D Formula: C15H17ClN2O2S · HCl Purity: >98% |
Cayman |
50 mg |
209 €
|
| Cay10010237-1 |
CAS: 35943-35-2 Akt inhibitor Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt. MW: 320 D Formula: C13H16N6O4 Purity: >98% |
Cayman |
1 mg |
136 €
|
| Cay10010237-10 |
CAS: 35943-35-2 Akt inhibitor Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt. MW: 320 D Formula: C13H16N6O4 Purity: >98% |
Cayman |
10 mg |
1086 €
|
| Cay10010237-5 |
CAS: 35943-35-2 Akt inhibitor Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt. MW: 320 D Formula: C13H16N6O4 Purity: >98% |
Cayman |
5 mg |
611 €
|
| Cay10010239-10 |
CAS: 142273-20-9 CDK inhibitor, GSK-3 beta inhibitor Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta). MW: 327 D Formula: C16H11BrN2O Purity: >98% |
Cayman |
10 mg |
362 €
|
| Cay10010239-5 |
CAS: 142273-20-9 CDK inhibitor, GSK-3 beta inhibitor Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta). MW: 327 D Formula: C16H11BrN2O Purity: >98% |
Cayman |
5 mg |
199 €
|
| Cay10010239-50 |
CAS: 142273-20-9 CDK inhibitor, GSK-3 beta inhibitor Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta). MW: 327 D Formula: C16H11BrN2O Purity: >98% |
Cayman |
50 mg |
1583 €
|
| Cay10010240-10 |
CAS: 101622-51-9 CDK inhibitor Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM). MW: 298 D Purity: >98% |
Cayman |
10 mg |
158 €
|
| Cay10010240-25 |
CAS: 101622-51-9 CDK inhibitor Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM). MW: 298 D Purity: >98% |
Cayman |
25 mg |
346 €
|
| Cay10010240-5 |
CAS: 101622-51-9 CDK inhibitor Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM). MW: 298 D Purity: >98% |
Cayman |
5 mg |
89 €
|
| Cay10010246-10 |
CAS: 280744-09-4 GSK inhibitor SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway. MW: 371 D Formula: C19H12Cl2N2O2 Purity: >98% |
Cayman |
10 mg |
130 €
|
| Cay10010246-100 |
CAS: 280744-09-4 GSK inhibitor SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway. MW: 371 D Formula: C19H12Cl2N2O2 Purity: >98% |
Cayman |
100 mg |
958 €
|
| Cay10010246-5 |
CAS: 280744-09-4 GSK inhibitor SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway. MW: 371 D Formula: C19H12Cl2N2O2 Purity: >98% |
Cayman |
5 mg |
68 €
|
| Cay10010246-50 |
CAS: 280744-09-4 GSK inhibitor SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway. MW: 371 D Formula: C19H12Cl2N2O2 Purity: >98% |
Cayman |
50 mg |
548 €
|
| Cay10010247-10 |
CAS: 264218-23-7 GSK inhibitor SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 78 nM (similar potency for GSK3 beta and a Ki value of 31 nM). MW: 359 D Formula: C16H10ClN3O5 Purity: >98% |
Cayman |
10 mg |
341 €
|
| Cay10010247-5 |
CAS: 264218-23-7 GSK inhibitor SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 78 nM (similar potency for GSK3 beta and a Ki value of 31 nM). MW: 359 D Formula: C16H10ClN3O5 Purity: >98% |
Cayman |
5 mg |
195 €
|
| Cay10010249-10 |
CAS: 113276-94-1 PKA inhibitor, PKG inhibitor H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively. MW: 338 D Formula: C12H15N3O2S · 2HCl Purity: >98% |
Cayman |
10 mg |
87 €
|
| Cay10010249-25 |
CAS: 113276-94-1 PKA inhibitor, PKG inhibitor H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively. MW: 338 D Formula: C12H15N3O2S · 2HCl Purity: >98% |
Cayman |
25 mg |
195 €
|
| Cay10010249-5 |
CAS: 113276-94-1 PKA inhibitor, PKG inhibitor H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively. MW: 338 D Formula: C12H15N3O2S · 2HCl Purity: >98% |
Cayman |
5 mg |
44 €
|
| Cay10010249-50 |
CAS: 113276-94-1 PKA inhibitor, PKG inhibitor H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively. MW: 338 D Formula: C12H15N3O2S · 2HCl Purity: >98% |
Cayman |
50 mg |
346 €
|
| Cay10010267-10 |
CAS: 354812-17-2 IKK2 inhibitor SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes. MW: 224 D Formula: C9H8N2OS2 Purity: >98% |
Cayman |
10 mg |
78 €
|
| Cay10010267-25 |
CAS: 354812-17-2 IKK2 inhibitor SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes. MW: 224 D Formula: C9H8N2OS2 Purity: >98% |
Cayman |
25 mg |
183 €
|
| Cay10010267-50 |
CAS: 354812-17-2 IKK2 inhibitor SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes. MW: 224 D Formula: C9H8N2OS2 Purity: >98% |
Cayman |
50 mg |
325 €
|
| Cay10010275-100 |
CAS: 520-36-5 CK2 inhibitor Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2). MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
100 mg |
199 €
|
| Cay10010275-25 |
CAS: 520-36-5 CK2 inhibitor Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2). MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
25 mg |
56 €
|
| Cay10010275-50 |
CAS: 520-36-5 CK2 inhibitor Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2). MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
50 mg |
106 €
|
| Cay10010275-500 |
CAS: 520-36-5 CK2 inhibitor Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2). MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
500 mg |
891 €
|
| Cay10010301-10 |
CAS: 267654-00-2 CDK5 inhibitor, CDK2 inhibitor CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. MW: 260 D Formula: C14H16N2OS Purity: >95% |
Cayman |
10 mg |
113 €
|
| Cay10010301-25 |
CAS: 267654-00-2 CDK5 inhibitor, CDK2 inhibitor CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. MW: 260 D Formula: C14H16N2OS Purity: >95% |
Cayman |
25 mg |
267 €
|
| Cay10010301-5 |
CAS: 267654-00-2 CDK5 inhibitor, CDK2 inhibitor CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. MW: 260 D Formula: C14H16N2OS Purity: >95% |
Cayman |
5 mg |
59 €
|
| Cay10010301-50 |
CAS: 267654-00-2 CDK5 inhibitor, CDK2 inhibitor CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively. MW: 260 D Formula: C14H16N2OS Purity: >95% |
Cayman |
50 mg |
473 €
|
| Cay10010302-100 |
CAS: 53-85-0 CTD kinase inhibitor DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM). MW: 319 D Formula: C12H12Cl1N2O4 Purity: >98% |
Cayman |
100 mg |
223 €
|
| Cay10010302-250 |
CAS: 53-85-0 CTD kinase inhibitor DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM). MW: 319 D Formula: C12H12Cl1N2O4 Purity: >98% |
Cayman |
250 mg |
487 €
|
| Cay10010302-50 |
CAS: 53-85-0 CTD kinase inhibitor DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM). MW: 319 D Formula: C12H12Cl1N2O4 Purity: >98% |
Cayman |
50 mg |
125 €
|
| Cay10010367-1 |
CAS: 208260-29-1 Raf-1 inhibitor ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells. Activation of the Raf-1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr MW: 389 D Formula: C23H23N3O3 Purity: >98% |
Cayman |
1 mg |
30 €
|
| Cay10010367-10 |
CAS: 208260-29-1 Raf-1 inhibitor ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells. Activation of the Raf-1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr MW: 389 D Formula: C23H23N3O3 Purity: >98% |
Cayman |
10 mg |
241 €
|
| Cay10010367-25 |
CAS: 208260-29-1 Raf-1 inhibitor ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells. Activation of the Raf-1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr MW: 389 D Formula: C23H23N3O3 Purity: >98% |
Cayman |
25 mg |
528 €
|
| Cay10010367-5 |
CAS: 208260-29-1 Raf-1 inhibitor ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells. Activation of the Raf-1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr MW: 389 D Formula: C23H23N3O3 Purity: >98% |
Cayman |
5 mg |
136 €
|
| Cay10010375-1 |
CAS: 24386-93-4 MAPK Inhibitor 5-Iodotubercidin can inhibit a broad range of PKs including PKA (IC50 = 5-10 µM), phosphorylase kinase (IC50 = 5-10 µM), casein kinase I (IC50 = 0.4 µM) and II (IC50 = 10.9 µM), and PKC (IC50 = 0.4 µM) andERK2 (Ki = 525 nM). MW: 392 D Formula: C11H13IN4O4 Purity: >95% |
Cayman |
1 mg |
90 €
|
| Cay10010375-5 |
CAS: 24386-93-4 MAPK Inhibitor 5-Iodotubercidin can inhibit a broad range of PKs including PKA (IC50 = 5-10 µM), phosphorylase kinase (IC50 = 5-10 µM), casein kinase I (IC50 = 0.4 µM) and II (IC50 = 10.9 µM), and PKC (IC50 = 0.4 µM) andERK2 (Ki = 525 nM). MW: 392 D Formula: C11H13IN4O4 Purity: >95% |
Cayman |
5 mg |
299 €
|
| Cay10010399-10 |
CAS: 152121-30-7 MAP kinases Inhibitor SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a ... mehr MW: 331 D Formula: C20H14FN3O Purity: >98% |
Cayman |
10 mg |
29 €
|
| Cay10010399-25 |
CAS: 152121-30-7 MAP kinases Inhibitor SB 202190 is a selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a ... mehr MW: 331 D Formula: C20H14FN3O Purity: >98% |
Cayman |
25 mg |
56 €
|
| Cay10010466-10 |
CAS: 129-56-6 JNK inhibitor SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells., MW: 220 D Formula: C14H8N2O Purity: >98% |
Cayman |
10 mg |
81 €
|
| Cay10010466-25 |
CAS: 129-56-6 JNK inhibitor SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells., MW: 220 D Formula: C14H8N2O Purity: >98% |
Cayman |
25 mg |
194 €
|
| Cay10010466-50 |
CAS: 129-56-6 JNK inhibitor SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells., MW: 220 D Formula: C14H8N2O Purity: >98% |
Cayman |
50 mg |
343 €
|
| Cay10010541-10 |
CAS: 25695-95-8 PKC inhibitor L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %. MW: 299 D Formula: C18H37NO2 Purity: >98% |
Cayman |
10 mg |
220 €
|
| Cay10010541-100 |
CAS: 25695-95-8 PKC inhibitor L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %. MW: 299 D Formula: C18H37NO2 Purity: >98% |
Cayman |
100 mg |
1624 €
|
| Cay10010541-5 |
CAS: 25695-95-8 PKC inhibitor L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %. MW: 299 D Formula: C18H37NO2 Purity: >98% |
Cayman |
5 mg |
116 €
|
| Cay10010541-50 |
CAS: 25695-95-8 PKC inhibitor L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %. MW: 299 D Formula: C18H37NO2 Purity: >98% |
Cayman |
50 mg |
928 €
|
| Cay10010556-10 |
CAS: 127243-85-0 PKA inhibitor H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b. MW: 446 D Formula: C20H20BrN3O2S Purity: >98% |
Cayman |
10 mg |
99 €
|
| Cay10010556-25 |
CAS: 127243-85-0 PKA inhibitor H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b. MW: 446 D Formula: C20H20BrN3O2S Purity: >98% |
Cayman |
25 mg |
240 €
|
| Cay10010556-50 |
CAS: 127243-85-0 PKA inhibitor H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b. MW: 446 D Formula: C20H20BrN3O2S Purity: >98% |
Cayman |
50 mg |
427 €
|
| Cay10010559-100 |
CAS: 203911-27-7 ROCK-II inhibitor HA-1077 is a potent inhibitor of ROCK-II and additionally inhibits Protein Kinase C-related Kinase 2 (PRK2), Mitogen- and Stress-Activated Protein Kinase (MSK1), and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively. MW: 364 D Formula: C14H17N3O2S . 2HCl Purity: >98% |
Cayman |
100 mg |
747 €
|
| Cay10010559-50 |
CAS: 203911-27-7 ROCK-II inhibitor HA-1077 is a potent inhibitor of ROCK-II and additionally inhibits Protein Kinase C-related Kinase 2 (PRK2), Mitogen- and Stress-Activated Protein Kinase (MSK1), and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively. MW: 364 D Formula: C14H17N3O2S . 2HCl Purity: >98% |
Cayman |
50 mg |
427 €
|
| Cay10010965-100 |
CAS: 126643-37-6 PKG inhibitor KT 5823 is a potent, selective inhibitor of PKG (in vitro IC50 = 234 nM). It is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells. MW: 495 D Formula: C29H25N3O5 Purity: >95% |
Cayman |
100 µg |
117 €
|
| Cay10010965-250 |
CAS: 126643-37-6 PKG inhibitor KT 5823 is a potent, selective inhibitor of PKG (in vitro IC50 = 234 nM). It is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells. MW: 495 D Formula: C29H25N3O5 Purity: >95% |
Cayman |
250 µg |
260 €
|
| Cay10011011-0.05 |
CAS: 108068-98-0 PKA inhibitor Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta. MW: 537 D Formula: C32H31N3O5 Purity: >98% |
Cayman |
50 µg |
80 €
|
| Cay10011011-0.1 |
CAS: 108068-98-0 PKA inhibitor Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta. MW: 537 D Formula: C32H31N3O5 Purity: >98% |
Cayman |
100 µg |
152 €
|
| Cay10011011-0.25 |
CAS: 108068-98-0 PKA inhibitor Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta. MW: 537 D Formula: C32H31N3O5 Purity: >98% |
Cayman |
250 µg |
361 €
|
| Cay10011011-0.5 |
CAS: 108068-98-0 PKA inhibitor Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta. MW: 537 D Formula: C32H31N3O5 Purity: >98% |
Cayman |
500 µg |
640 €
|
| Cay10011247-10 |
CAS: 140651-18-9 CDK9 inhibitor CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E. MW: 218 D Formula: C9H10N6O Purity: >95% |
Cayman |
10 mg |
176 €
|
| Cay10011247-5 |
CAS: 140651-18-9 CDK9 inhibitor CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E. MW: 218 D Formula: C9H10N6O Purity: >95% |
Cayman |
5 mg |
99 €
|
| Cay10011247-50 |
CAS: 140651-18-9 CDK9 inhibitor CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E. MW: 218 D Formula: C9H10N6O Purity: >95% |
Cayman |
50 mg |
771 €
|
| Cay10011248-10 |
CAS: 916985-21-2 IKKepsilon inhibitor CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM. MW: 487 D Formula: C22H21N3O6S2 Purity: >95% |
Cayman |
10 mg |
232 €
|
| Cay10011248-25 |
CAS: 916985-21-2 IKKepsilon inhibitor CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM. MW: 487 D Formula: C22H21N3O6S2 Purity: >95% |
Cayman |
25 mg |
499 €
|
| Cay10011248-5 |
CAS: 916985-21-2 IKKepsilon inhibitor CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM. MW: 487 D Formula: C22H21N3O6S2 Purity: >95% |
Cayman |
5 mg |
131 €
|
| Cay10011249-10 |
CAS: 862812-98-4 IKKepsilon inhibitor CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta. MW: 469 D Formula: C22H19N3O5S2 Purity: >95% |
Cayman |
10 mg |
334 €
|
| Cay10011249-5 |
CAS: 862812-98-4 IKKepsilon inhibitor CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta. MW: 469 D Formula: C22H19N3O5S2 Purity: >95% |
Cayman |
5 mg |
188 €
|
| Cay10011249-50 |
CAS: 862812-98-4 IKKepsilon inhibitor CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta. MW: 469 D Formula: C22H19N3O5S2 Purity: >95% |
Cayman |
50 mg |
1462 €
|
| Cay10011250-10 |
CAS: 278603-08-0 eEF-2K inhibitor In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM). MW: 524 D Formula: C27H45IN2 Purity: >95% |
Cayman |
10 mg |
251 €
|
| Cay10011250-5 |
CAS: 278603-08-0 eEF-2K inhibitor In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM). MW: 524 D Formula: C27H45IN2 Purity: >95% |
Cayman |
5 mg |
142 €
|
| Cay10011250-50 |
CAS: 278603-08-0 eEF-2K inhibitor In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM). MW: 524 D Formula: C27H45IN2 Purity: >95% |
Cayman |
50 mg |
1096 €
|
| Cay10011251-10 |
CAS: 601514-19-6 GSK3beta inhibitor TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. MW: 318 D Formula: C18H14N4O2 Purity: >90% |
Cayman |
10 mg |
334 €
|
| Cay10011251-25 |
CAS: 601514-19-6 GSK3beta inhibitor TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. MW: 318 D Formula: C18H14N4O2 Purity: >90% |
Cayman |
25 mg |
731 €
|
| Cay10011251-5 |
CAS: 601514-19-6 GSK3beta inhibitor TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation. MW: 318 D Formula: C18H14N4O2 Purity: >90% |
Cayman |
5 mg |
188 €
|
| Cay10011255-10 |
CAS: 51726-83-1 CK2 inhibitor NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases. MW: 239 D Formula: C14H9NO3 Purity: >95% |
Cayman |
10 mg |
121 €
|
| Cay10011255-5 |
CAS: 51726-83-1 CK2 inhibitor NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases. MW: 239 D Formula: C14H9NO3 Purity: >95% |
Cayman |
5 mg |
68 €
|
| Cay10011255-50 |
CAS: 51726-83-1 CK2 inhibitor NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases. MW: 239 D Formula: C14H9NO3 Purity: >95% |
Cayman |
50 mg |
528 €
|
| Cay10011256-10 |
CAS: 300675-28-9 CK2 inhibitor Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM. MW: 258 D Formula: C10H5Cl2NO3 Purity: >95% |
Cayman |
10 mg |
121 €
|
| Cay10011256-5 |
CAS: 300675-28-9 CK2 inhibitor Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM. MW: 258 D Formula: C10H5Cl2NO3 Purity: >95% |
Cayman |
5 mg |
68 €
|
| Cay10011256-50 |
CAS: 300675-28-9 CK2 inhibitor Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM. MW: 258 D Formula: C10H5Cl2NO3 Purity: >95% |
Cayman |
50 mg |
528 €
|
| Cay10011264-10 |
CAS: 19231-60-8 CK2 inhibitor CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1). MW: 708 D Formula: C10H3I4NO4 Purity: >95% |
Cayman |
10 mg |
121 €
|
| Cay10011264-25 |
CAS: 19231-60-8 CK2 inhibitor CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1). MW: 708 D Formula: C10H3I4NO4 Purity: >95% |
Cayman |
25 mg |
264 €
|
| Cay10011264-5 |
CAS: 19231-60-8 CK2 inhibitor CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1). MW: 708 D Formula: C10H3I4NO4 Purity: >95% |
Cayman |
5 mg |
68 €
|
| Cay10011490-100 |
CAS: 78111-17-8 PP1 PP2A PP3 inhibitor Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr MW: 805 D Formula: C44H68O13 Purity: >95% |
Cayman |
100 µg |
113 €
|
| Cay10011490-25 |
CAS: 78111-17-8 PP1 PP2A PP3 inhibitor Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr MW: 805 D Formula: C44H68O13 Purity: >95% |
Cayman |
25 µg |
31 €
|
| Cay10011490-50 |
CAS: 78111-17-8 PP1 PP2A PP3 inhibitor Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr MW: 805 D Formula: C44H68O13 Purity: >95% |
Cayman |
50 µg |
59 €
|
| Cay10398-1 |
CAS: 300801-52-9 Cdc2 kinase inhibitor Specific ATP-competitive inhibitor of Cdc2-like kinase. MW: 249 D Formula: C13H15NO2S Purity: >95% |
Cayman |
1 mg |
21 €
|
| Cay10398-10 |
CAS: 300801-52-9 Cdc2 kinase inhibitor Specific ATP-competitive inhibitor of Cdc2-like kinase. MW: 249 D Formula: C13H15NO2S Purity: >95% |
Cayman |
10 mg |
167 €
|
| Cay10398-25 |
CAS: 300801-52-9 Cdc2 kinase inhibitor Specific ATP-competitive inhibitor of Cdc2-like kinase. MW: 249 D Formula: C13H15NO2S Purity: >95% |
Cayman |
25 mg |
365 €
|
| Cay10398-5 |
CAS: 300801-52-9 Cdc2 kinase inhibitor Specific ATP-competitive inhibitor of Cdc2-like kinase. MW: 249 D Formula: C13H15NO2S Purity: >95% |
Cayman |
5 mg |
94 €
|
| Cay10527-25 |
CAS: 337349-54-9 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 383 D Formula: C19H17N3O2S2 Purity: >98% |
Cayman |
25 mg |
183 €
|
| Cay10527-5 |
CAS: 337349-54-9 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 383 D Formula: C19H17N3O2S2 Purity: >98% |
Cayman |
5 mg |
41 €
|
| Cay10876-10 |
CAS: 871361-88-5 AKT inhibitor SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt. MW: 276 D Formula: C18H16N2O Purity: >98% |
Cayman |
10 mg |
84 €
|
| Cay10876-100 |
CAS: 871361-88-5 AKT inhibitor SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt. MW: 276 D Formula: C18H16N2O Purity: >98% |
Cayman |
100 mg |
607 €
|
| Cay10876-25 |
CAS: 871361-88-5 AKT inhibitor SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt. MW: 276 D Formula: C18H16N2O Purity: >98% |
Cayman |
25 mg |
198 €
|
| Cay10876-5 |
CAS: 871361-88-5 AKT inhibitor SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt. MW: 276 D Formula: C18H16N2O Purity: >98% |
Cayman |
5 mg |
44 €
|
| Cay10997-10 |
CAS: 1222998-36-8 mTor inhibitor Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kalpha and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other p ... mehr MW: 607 D Formula: C35H28F3N5O2 Purity: >95% |
Cayman |
10 mg |
114 €
|
| Cay10997-25 |
CAS: 1222998-36-8 mTor inhibitor Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kalpha and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other p ... mehr MW: 607 D Formula: C35H28F3N5O2 Purity: >95% |
Cayman |
25 mg |
313 €
|
| Cay10997-50 |
CAS: 1222998-36-8 mTor inhibitor Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kalpha and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other p ... mehr MW: 607 D Formula: C35H28F3N5O2 Purity: >95% |
Cayman |
50 mg |
512 €
|
| Cay11020-1 |
CAS: 137592-45-1 PKC inhibitor Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A MW: 438 D Formula: C27H26N4O2 Purity: >97% |
Cayman |
1 mg |
52 €
|
| Cay11020-5 |
CAS: 137592-45-1 PKC inhibitor Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A MW: 438 D Formula: C27H26N4O2 Purity: >97% |
Cayman |
5 mg |
162 €
|
| Cay11072-1 |
CAS: 137592-43-9 PKC inhibitor Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other ... mehr MW: 384 D Formula: C23H20N4O2 Purity: >98% |
Cayman |
1 mg |
52 €
|
| Cay11072-5 |
CAS: 137592-43-9 PKC inhibitor Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other ... mehr MW: 384 D Formula: C23H20N4O2 Purity: >98% |
Cayman |
5 mg |
162 €
|
| Cay11073-1 |
CAS: 145333-02-4 PKC inhibitor Ro 31-0432 MW: 489 D Formula: C28H28N4O2 HCl Purity: >98% |
Cayman |
1 mg |
75 €
|
| Cay11073-5 |
CAS: 145333-02-4 PKC inhibitor Ro 31-0432 MW: 489 D Formula: C28H28N4O2 HCl Purity: >98% |
Cayman |
5 mg |
340 €
|
| Cay11314-1 |
CAS: 3895-92-9 Inhibitor of protein kinase C Chelerythrine chloride is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. Chelerythrine also inhibits Bcl ... mehr MW: 383 D Formula: C21H18NO4 Cl Purity: >98% |
Cayman |
1 mg |
29 €
|
| Cay11314-5 |
CAS: 3895-92-9 Inhibitor of protein kinase C Chelerythrine chloride is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-dependent protein kinase, or calcium/calmodulin-dependent protein kinase. Chelerythrine also inhibits Bcl ... mehr MW: 383 D Formula: C21H18NO4 Cl Purity: >98% |
Cayman |
5 mg |
75 €
|
| Cay11338-1 |
CAS: 99533-80-9 Kinase inhibitor K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr MW: 467 D Formula: C27H21N3O5 Purity: >98% |
Cayman |
1 mg |
455 €
|
| Cay11338-100 |
CAS: 99533-80-9 Kinase inhibitor K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr MW: 467 D Formula: C27H21N3O5 Purity: >98% |
Cayman |
100 µg |
114 €
|
| Cay11658-10 |
CAS: 4311-88-0 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 259 D Formula: C13H13N3OS Purity: >98% |
Cayman |
10 mg |
58 €
|
| Cay11658-100 |
CAS: 4311-88-0 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 259 D Formula: C13H13N3OS Purity: >98% |
Cayman |
100 mg |
325 €
|
| Cay11658-5 |
CAS: 4311-88-0 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 259 D Formula: C13H13N3OS Purity: >98% |
Cayman |
5 mg |
32 €
|
| Cay11658-50 |
CAS: 4311-88-0 RIP1 kinase inhibitor Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-associated molecule RIP1 is thought to be essential for Fas ligan ... mehr MW: 259 D Formula: C13H13N3OS Purity: >98% |
Cayman |
50 mg |
195 €
|
Cay11704-1 |
CAS: 77307-50-7 RSK2 inhibitor The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. SL 0101-1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr MW: 516 D Formula: C25H24O12 Purity: >98% |
Cayman |
1 mg |
161 €
|
|
Cay11704-5 |
CAS: 77307-50-7 RSK2 inhibitor The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. SL 0101-1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr MW: 516 D Formula: C25H24O12 Purity: >98% |
Cayman |
5 mg |
677 €
|
|
Cay11704-500 |
CAS: 77307-50-7 RSK2 inhibitor The p90 ribosomal S6 kinases (RSK) 1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. SL 0101-1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr MW: 516 D Formula: C25H24O12 Purity: >98% |
Cayman |
500 µg |
85 €
|
| Cay11793-1 |
CAS: 694433-59-5 ALK5 inhibitor SB 505124 inhibits the TGF-beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7 ... mehr MW: 335 D Formula: C20H21N3O2 Purity: >98% |
Cayman |
1 mg |
30 €
|
| Cay11793-10 |
CAS: 694433-59-5 ALK5 inhibitor SB 505124 inhibits the TGF-beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7 ... mehr MW: 335 D Formula: C20H21N3O2 Purity: >98% |
Cayman |
10 mg |
181 €
|
| Cay11793-25 |
CAS: 694433-59-5 ALK5 inhibitor SB 505124 inhibits the TGF-beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7 ... mehr MW: 335 D Formula: C20H21N3O2 Purity: >98% |
Cayman |
25 mg |
340 €
|
| Cay11793-5 |
CAS: 694433-59-5 ALK5 inhibitor SB 505124 inhibits the TGF-beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-dependently inhibits ALK4-, ALK5-, and ALK7 ... mehr MW: 335 D Formula: C20H21N3O2 Purity: >98% |
Cayman |
5 mg |
121 €
|
| Cay11801-1 |
CAS: 110448-33-4 MLCK inhibitor ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of M ... mehr MW: 452 D Formula: C15H17IN2O2S - HCl Purity: >95% |
Cayman |
1 mg |
22 €
|
| Cay11801-10 |
CAS: 110448-33-4 MLCK inhibitor ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of M ... mehr MW: 452 D Formula: C15H17IN2O2S - HCl Purity: >95% |
Cayman |
10 mg |
122 €
|
| Cay11801-5 |
CAS: 110448-33-4 MLCK inhibitor ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of M ... mehr MW: 452 D Formula: C15H17IN2O2S - HCl Purity: >95% |
Cayman |
5 mg |
82 €
|
| Cay11801-50 |
CAS: 110448-33-4 MLCK inhibitor ML-7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-competitive inhibition of Ca2+calmodulin-dependent and -independent smooth muscle MLCKs. It exhibits a 10-fold more potent inhibition of M ... mehr MW: 452 D Formula: C15H17IN2O2S - HCl Purity: >95% |
Cayman |
50 mg |
276 €
|
| Cay11811-1 |
CAS: 1224844-38-5 TORC1 / 2 inhibitor The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr MW: 309 Formula: C15H15N7O Purity: >98% |
Cayman |
1 mg |
57 €
|
| Cay11811-10 |
CAS: 1224844-38-5 TORC1 / 2 inhibitor The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr MW: 309 Formula: C15H15N7O Purity: >98% |
Cayman |
10 mg |
455 €
|
| Cay11811-5 |
CAS: 1224844-38-5 TORC1 / 2 inhibitor The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr MW: 309 Formula: C15H15N7O Purity: >98% |
Cayman |
5 mg |
256 €
|
| Cay13031-10 |
CAS: 301836-41-9 ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation. MW: 384 D Formula: C22H16N4O3 Purity: >98% |
Cayman |
10 mg |
167 €
|
| Cay13031-25 |
CAS: 301836-41-9 ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation. MW: 384 D Formula: C22H16N4O3 Purity: >98% |
Cayman |
25 mg |
365 €
|
| Cay13031-5 |
CAS: 301836-41-9 ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation. MW: 384 D Formula: C22H16N4O3 Purity: >98% |
Cayman |
5 mg |
94 €
|
| Cay13067-10 |
CAS: 152121-47-6 p38 MAPK inhibitor SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK. MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Cayman |
10 mg |
172 €
|
| Cay13067-100 |
CAS: 152121-47-6 p38 MAPK inhibitor SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK. MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Cayman |
100 mg |
1267 €
|
| Cay13067-5 |
CAS: 152121-47-6 p38 MAPK inhibitor SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK. MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Cayman |
5 mg |
90 €
|
| Cay13067-50 |
CAS: 152121-47-6 p38 MAPK inhibitor SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK. MW: 377 D Formula: C21H16FN3OS Purity: >98% |
Cayman |
50 mg |
724 €
|
| Cay13108-10 |
CAS: 745833-23-2 p38 MAP kinase inhibitor VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNFalpha production in LPS-primed ... mehr MW: 404 D Formula: C19H12F4N4O2 Purity: >98% |
Cayman |
10 mg |
42 €
|
| Cay13108-25 |
CAS: 745833-23-2 p38 MAP kinase inhibitor VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNFalpha production in LPS-primed ... mehr MW: 404 D Formula: C19H12F4N4O2 Purity: >98% |
Cayman |
25 mg |
99 €
|
| Cay13108-5 |
CAS: 745833-23-2 p38 MAP kinase inhibitor VX-702 is a third generation inhibitor of p38 mitogen-activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-competitive fashion. It inhibits IL-6, IL-1beta, and TNFalpha production in LPS-primed ... mehr MW: 404 D Formula: C19H12F4N4O2 Purity: >98% |
Cayman |
5 mg |
22 €
|
| Cay13109-100 |
CAS: 518-82-1 CK2 inhibitor Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
100 mg |
104 €
|
| Cay13109-25 |
CAS: 518-82-1 CK2 inhibitor Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
25 mg |
29 €
|
| Cay13109-50 |
CAS: 518-82-1 CK2 inhibitor Emodin is a naturally-occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr MW: 270 D Formula: C15H10O5 Purity: >98% |
Cayman |
50 mg |
56 €
|
| Cay13122-1 |
CAS: 252917-06-9 GSK3alpha and GSK3beta inhibitor Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr MW: 465 Formula: C22H18Cl2N8 Purity: >98% |
Cayman |
1 mg |
49 €
|
| Cay13122-10 |
CAS: 252917-06-9 GSK3alpha and GSK3beta inhibitor Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr MW: 465 Formula: C22H18Cl2N8 Purity: >98% |
Cayman |
10 mg |
390 €
|
| Cay13122-5 |
CAS: 252917-06-9 GSK3alpha and GSK3beta inhibitor Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr MW: 465 Formula: C22H18Cl2N8 Purity: >98% |
Cayman |
5 mg |
219 €
|
| Cay13123-10 |
CAS: 667463-62-9 GSK-3 inhibitor Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells. MW: 356 D Formula: C16H10BrN3O2 Purity: >98% |
Cayman |
10 mg |
223 €
|
| Cay13123-25 |
CAS: 667463-62-9 GSK-3 inhibitor Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells. MW: 356 D Formula: C16H10BrN3O2 Purity: >98% |
Cayman |
25 mg |
487 €
|
| Cay13123-5 |
CAS: 667463-62-9 GSK-3 inhibitor Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells. MW: 356 D Formula: C16H10BrN3O2 Purity: >98% |
Cayman |
5 mg |
125 €
|
| Cay13297-10 |
CAS: 118409-62-4 ERK inhibitor The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo. MW: 215 D Formula: C10H5N3O3 Purity: >95% |
Cayman |
10 mg |
223 €
|
| Cay13297-25 |
CAS: 118409-62-4 ERK inhibitor The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo. MW: 215 D Formula: C10H5N3O3 Purity: >95% |
Cayman |
25 mg |
487 €
|
| Cay13297-5 |
CAS: 118409-62-4 ERK inhibitor The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo. MW: 215 D Formula: C10H5N3O3 Purity: >95% |
Cayman |
5 mg |
125 €
|
| Cay13298-10 |
CAS: 133052-90-1 PKC inhibitor Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC. MW: 412 D Formula: C25H24N4O2 Purity: >95% |
Cayman |
10 mg |
152 €
|
| Cay13298-25 |
CAS: 133052-90-1 PKC inhibitor Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC. MW: 412 D Formula: C25H24N4O2 Purity: >95% |
Cayman |
25 mg |
361 €
|
| Cay13298-5 |
CAS: 133052-90-1 PKC inhibitor Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC. MW: 412 D Formula: C25H24N4O2 Purity: >95% |
Cayman |
5 mg |
80 €
|
| Cay13298-50 |
CAS: 133052-90-1 PKC inhibitor Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC. MW: 412 D Formula: C25H24N4O2 Purity: >95% |
Cayman |
50 mg |
640 €
|
| Cay13299-10 |
CAS: 119139-23-0 PKC inhibitor Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM). MW: 327 D Formula: C20H13N3O2 Purity: >98% |
Cayman |
10 mg |
380 €
|
| Cay13299-25 |
CAS: 119139-23-0 PKC inhibitor Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM). MW: 327 D Formula: C20H13N3O2 Purity: >98% |
Cayman |
25 mg |
833 €
|
| Cay13299-5 |
CAS: 119139-23-0 PKC inhibitor Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM). MW: 327 D Formula: C20H13N3O2 Purity: >98% |
Cayman |
5 mg |
215 €
|
| Cay13300-1 |
CAS: 113963-68-1 S6K inhibitor Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo. MW: 341 D Formula: C21H15N3O2 Purity: >98% |
Cayman |
1 mg |
59 €
|
| Cay13300-10 |
CAS: 113963-68-1 S6K inhibitor Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo. MW: 341 D Formula: C21H15N3O2 Purity: >98% |
Cayman |
10 mg |
473 €
|
| Cay13300-25 |
CAS: 113963-68-1 S6K inhibitor Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo. MW: 341 D Formula: C21H15N3O2 Purity: >98% |
Cayman |
25 mg |
1036 €
|
| Cay13300-5 |
CAS: 113963-68-1 S6K inhibitor Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.(±)-7-epi Jasmonic acid is a plant growth regulator ... mehr MW: 341 D Formula: C21H15N3O2 Purity: >98% |
Cayman |
5 mg |
267 €
|
| Cay13305-10 |
CAS: 301836-43-1 CK1 inhibitor Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53. MW: 398 D Formula: C23H18N4O3 Purity: >98% |
Cayman |
10 mg |
176 €
|
| Cay13305-5 |
CAS: 301836-43-1 CK1 inhibitor Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53. MW: 398 D Formula: C23H18N4O3 Purity: >98% |
Cayman |
5 mg |
99 €
|
| Cay13305-50 |
CAS: 301836-43-1 CK1 inhibitor Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53. MW: 398 D Formula: C23H18N4O3 Purity: >98% |
Cayman |
50 mg |
771 €
|
| Cay13308-10 |
CAS: 154447-35-5 DNA-PK inhibitor NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation. MW: 281 D Formula: C17H15NO3 Purity: >95% |
Cayman |
10 mg |
144 €
|
| Cay13308-25 |
CAS: 154447-35-5 DNA-PK inhibitor NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation. MW: 281 D Formula: C17H15NO3 Purity: >95% |
Cayman |
25 mg |
340 €
|
| Cay13308-5 |
CAS: 154447-35-5 DNA-PK inhibitor NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation. MW: 281 D Formula: C17H15NO3 Purity: >95% |
Cayman |
5 mg |
75 €
|
| Cay13308-50 |
CAS: 154447-35-5 DNA-PK inhibitor NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation. MW: 281 D Formula: C17H15NO3 Purity: >95% |
Cayman |
50 mg |
599 €
|
| Cay13311-10 |
CAS: 133053-19-7 PKC inhibitor Gö 6983 inhibits several isoforms of protein kinase C. It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction. MW: 442 D Formula: C26H26N4O3 Purity: >98% |
Cayman |
10 mg |
209 €
|
| Cay13311-25 |
CAS: 133053-19-7 PKC inhibitor Gö 6983 inhibits several isoforms of protein kinase C. It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction. MW: 442 D Formula: C26H26N4O3 Purity: >98% |
Cayman |
25 mg |
467 €
|
| Cay13311-5 |
CAS: 133053-19-7 PKC inhibitor Gö 6983 inhibits several isoforms of protein kinase C. It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction. MW: 442 D Formula: C26H26N4O3 Purity: >98% |
Cayman |
5 mg |
139 €
|
| Cay13312-25 |
Kinase inhibitor H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA. MW: 324 D Formula: C11H13N3O2S ? 2HCl Purity: >98% |
Cayman |
25 mg |
110 €
|
| Cay13312-50 |
Kinase inhibitor H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA. MW: 324 D Formula: C11H13N3O2S ? 2HCl Purity: >98% |
Cayman |
50 mg |
195 €
|
| Cay13314-10 |
CAS: 160807-49-8 GSK-3beta inhibitor, CDK inhibitor Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types. MW: 277 D Formula: C16H11N3O2 Purity: >98% |
Cayman |
10 mg |
135 €
|
| Cay13314-25 |
CAS: 160807-49-8 GSK-3beta inhibitor, CDK inhibitor Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types. MW: 277 D Formula: C16H11N3O2 Purity: >98% |
Cayman |
25 mg |
319 €
|
| Cay13314-5 |
CAS: 160807-49-8 GSK-3beta inhibitor, CDK inhibitor Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types. MW: 277 D Formula: C16H11N3O2 Purity: >98% |
Cayman |
5 mg |
71 €
|
| Cay13314-50 |
CAS: 160807-49-8 GSK-3beta inhibitor, CDK inhibitor Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types. MW: 277 D Formula: C16H11N3O2 Purity: >98% |
Cayman |
50 mg |
566 €
|
| Cay13318-10 |
CAS: 127191-97-3 CAMKII inhibitor Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7. MW: 721 D Formula: C38H35N5O6S2 Purity: >98% |
Cayman |
10 mg |
390 €
|
| Cay13318-25 |
CAS: 127191-97-3 CAMKII inhibitor Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7. MW: 721 D Formula: C38H35N5O6S2 Purity: >98% |
Cayman |
25 mg |
853 €
|
| Cay13318-5 |
CAS: 127191-97-3 CAMKII inhibitor Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7. MW: 721 D Formula: C38H35N5O6S2 Purity: >98% |
Cayman |
5 mg |
219 €
|
| Cay13319-1 |
CAS: 139298-40-1 CaMKII inhibitor KN-93 is a water-soluble, selective inhibitor of Ca2 dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells. MW: 501 D Formula: C26H29ClN2O4S Purity: >98% |
Cayman |
1 mg |
99 €
|
| Cay13319-10 |
CAS: 139298-40-1 CaMKII inhibitor KN-93 is a water-soluble, selective inhibitor of Ca2-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells. MW: 501 D Formula: C26H29ClN2O4S Purity: >98% |
Cayman |
10 mg |
798 €
|
| Cay13319-5 |
CAS: 139298-40-1 CaMKII inhibitor KN-93 is a water-soluble, selective inhibitor of Ca2-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells. MW: 501 D Formula: C26H29ClN2O4S Purity: >98% |
Cayman |
5 mg |
449 €
|
| Cay13322-10 |
CAS: 522629-08-9 MAPK-interacting kinase 1 inhibitor CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells. MW: 244 D Formula: C11H9FN6 Purity: >95% |
Cayman |
10 mg |
288 €
|
| Cay13322-25 |
CAS: 522629-08-9 MAPK-interacting kinase 1 inhibitor CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells. MW: 244 D Formula: C11H9FN6 Purity: >95% |
Cayman |
25 mg |
630 €
|
| Cay13322-5 |
CAS: 522629-08-9 MAPK-interacting kinase 1 inhibitor CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells. MW: 244 D Formula: C11H9FN6 Purity: >95% |
Cayman |
5 mg |
162 €
|
| Cay13332-1 |
CAS: 913844-45-8 ROCK inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 449 D Formula: C18H24N4O3S . 2HCl Purity: >98% |
Cayman |
1 mg |
166 €
|
| Cay13332-5 |
CAS: 913844-45-8 ROCK inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 449 D Formula: C18H24N4O3S . 2HCl Purity: >98% |
Cayman |
5 mg |
696 €
|
| Cay13332-500 |
CAS: 913844-45-8 ROCK inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 449 D Formula: C18H24N4O3S . 2HCl Purity: >98% |
Cayman |
500 µg |
87 €
|
| Cay13333-10 |
CAS: 138516-31-1 PKC inhibitor Ro 31-7549 is a selective protein kinase C inhibitor that acts at the ATP binding site of PKC (preference for PKCalpha). At 10 µM Ro 31-7549 does not inhibit the tyrosine phosphorylation or the activation of phospholipase C gamma1. MW: 458 D Formula: C24H22N4O2 ? C2H4O2 Purity: >98% |
Cayman |
10 mg |
316 €
|
| Cay13333-25 |
CAS: 138516-31-1 PKC inhibitor Ro 31-7549 is a selective protein kinase C inhibitor that acts at the ATP binding site of PKC (preference for PKCalpha). At 10 µM Ro 31-7549 does not inhibit the tyrosine phosphorylation or the activation of phospholipase C gamma1. MW: 458 D Formula: C24H22N4O2 ? C2H4O2 Purity: >98% |
Cayman |
25 mg |
690 €
|
| Cay13333-5 |
CAS: 138516-31-1 PKC inhibitor Ro 31-7549 is a selective protein kinase C inhibitor that acts at the ATP binding site of PKC (preference for PKCalpha). At 10 µM Ro 31-7549 does not inhibit the tyrosine phosphorylation or the activation of phospholipase C gamma1. MW: 458 D Formula: C24H22N4O2 ? C2H4O2 Purity: >98% |
Cayman |
5 mg |
177 €
|
| Cay13334-1 |
CAS: 138489-18-6 PKC inhibitor Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein ki ... mehr MW: 553 D Formula: C25H23N5O2S . CH4SO3 Purity: 98% |
Cayman |
1 mg |
26 €
|
| Cay13334-10 |
CAS: 138489-18-6 PKC inhibitor Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein ki ... mehr MW: 553 D Formula: C25H23N5O2S . CH4SO3 Purity: 98% |
Cayman |
10 mg |
199 €
|
| Cay13334-5 |
CAS: 138489-18-6 PKC inhibitor Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein ki ... mehr MW: 553 D Formula: C25H23N5O2S . CH4SO3 Purity: 98% |
Cayman |
5 mg |
115 €
|
| Cay13334-50 |
CAS: 138489-18-6 PKC inhibitor Ro 31-8220 is a potent, cell-permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-alpha, PKC-betaI, PKC-betaII, PKC-gamma, and PKC-epsilon, respectively). It is a poor inhibitor of protein ki ... mehr MW: 553 D Formula: C25H23N5O2S . CH4SO3 Purity: 98% |
Cayman |
50 mg |
893 €
|
| Cay13341-10 |
CAS: 396129-53-6 TGFbetaRI inhibitor Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells. MW: 272 D Formula: C17H12N4 Purity: >98% |
Cayman |
10 mg |
164 €
|
| Cay13341-25 |
CAS: 396129-53-6 TGFbetaRI inhibitor Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells. MW: 272 D Formula: C17H12N4 Purity: >98% |
Cayman |
25 mg |
386 €
|
| Cay13341-5 |
CAS: 396129-53-6 TGFbetaRI inhibitor Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells. MW: 272 D Formula: C17H12N4 Purity: >98% |
Cayman |
5 mg |
86 €
|
| Cay13341-50 |
CAS: 396129-53-6 TGFbetaRI inhibitor Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells. MW: 272 D Formula: C17H12N4 Purity: >98% |
Cayman |
50 mg |
687 €
|
| Cay13344-10 |
CAS: 869185-85-3 p38 MAPK inhibitor p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1. MW: 413 D Formula: C21H16FN3OS ? HCl Purity: >98% |
Cayman |
10 mg |
198 €
|
| Cay13344-25 |
CAS: 869185-85-3 p38 MAPK inhibitor p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1. MW: 413 D Formula: C21H16FN3OS ? HCl Purity: >98% |
Cayman |
25 mg |
470 €
|
| Cay13344-5 |
CAS: 869185-85-3 p38 MAPK inhibitor p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1. MW: 413 D Formula: C21H16FN3OS ? HCl Purity: >98% |
Cayman |
5 mg |
104 €
|
| Cay13344-50 |
CAS: 869185-85-3 p38 MAPK inhibitor p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1. MW: 413 D Formula: C21H16FN3OS ? HCl Purity: >98% |
Cayman |
50 mg |
835 €
|
| Cay13600-100 |
CAS: 639089-54-6 Aurora kinase inhibitor MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits prolifera ... mehr MW: 465 D Formula: C23H28N8OS Purity: >98% |
Cayman |
100 mg |
225 €
|
| Cay13600-25 |
CAS: 639089-54-6 Aurora kinase inhibitor MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits prolifera ... mehr MW: 465 D Formula: C23H28N8OS Purity: >98% |
Cayman |
25 mg |
63 €
|
| Cay13600-250 |
CAS: 639089-54-6 Aurora kinase inhibitor MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits prolifera ... mehr MW: 465 D Formula: C23H28N8OS Purity: >98% |
Cayman |
250 mg |
499 €
|
| Cay13600-50 |
CAS: 639089-54-6 Aurora kinase inhibitor MK 0457 is a potent pan-Aurora kinase inhibitor but favors Aurora A (Ki = 0.6 nM) over Aurora B (Ki = 18 nM) or Aurora C (Ki = 4.6 nM). It shows selectivity against a panel of more than 190 different protein kinases. MK 0457 effectively inhibits prolifera ... mehr MW: 465 D Formula: C23H28N8OS Purity: >98% |
Cayman |
50 mg |
119 €
|
| Cay13601-10 |
CAS: 331771-20-1 Aurora B kinase inhibitor The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr MW: 514 D Formula: C29H31N5O4 |
Cayman |
10 mg |
99 €
|
| Cay13601-100 |
CAS: 331771-20-1 Aurora B kinase inhibitor The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr MW: 514 D Formula: C29H31N5O4 |
Cayman |
100 mg |
1150 €
|
| Cay13601-5 |
CAS: 331771-20-1 Aurora B kinase inhibitor The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr MW: 514 D Formula: C29H31N5O4 |
Cayman |
5 mg |
56 €
|
| Cay13601-50 |
CAS: 331771-20-1 Aurora B kinase inhibitor The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr MW: 514 D Formula: C29H31N5O4 |
Cayman |
50 mg |
334 €
|
| Cay13604-10 |
CAS: 1062169-56-5 mTOR inhibitor WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr MW: 495 D Formula: C24H29N7O5 Purity: >98% |
Cayman |
10 mg |
166 €
|
| Cay13604-25 |
CAS: 1062169-56-5 mTOR inhibitor WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr MW: 495 D Formula: C24H29N7O5 Purity: >98% |
Cayman |
25 mg |
392 €
|
| Cay13604-5 |
CAS: 1062169-56-5 mTOR inhibitor WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr MW: 495 D Formula: C24H29N7O5 Purity: >98% |
Cayman |
5 mg |
87 €
|
| Cay13604-50 |
CAS: 1062169-56-5 mTOR inhibitor WYE-354 is a potent cell-permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr MW: 495 D Formula: C24H29N7O5 Purity: >98% |
Cayman |
50 mg |
696 €
|
| Cay13641-1 |
IGF-1R kinase inhibitor Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-1R signaling has been implicated in the development and progre ... mehr MW: 512 D Formula: C27H29N5O . 2HCl Purity: >98% |
Cayman |
1 mg |
110 €
|
| Cay13641-10 |
IGF-1R kinase inhibitor Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-1R signaling has been implicated in the development and progre ... mehr MW: 512 D Formula: C27H29N5O . 2HCl Purity: >98% |
Cayman |
10 mg |
731 €
|
| Cay13641-5 |
IGF-1R kinase inhibitor Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-1R signaling has been implicated in the development and progre ... mehr MW: 512 D Formula: C27H29N5O . 2HCl Purity: >98% |
Cayman |
5 mg |
418 €
|
| Cay13641-500 |
IGF-1R kinase inhibitor Insulin-like growth factor 1 receptor (IGF-1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-1R signaling has been implicated in the development and progre ... mehr MW: 512 D Formula: C27H29N5O . 2HCl Purity: >98% |
Cayman |
500 µg |
75 €
|
| Cay13643-1 |
CAS: 1092351-67-1 mTOR kinase inhibitor The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr MW: 308 D Formula: C16H16N6O Purity: >95% |
Cayman |
1 mg |
20 €
|
| Cay13643-10 |
CAS: 1092351-67-1 mTOR kinase inhibitor The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr MW: 308 D Formula: C16H16N6O Purity: >95% |
Cayman |
10 mg |
137 €
|
| Cay13643-5 |
CAS: 1092351-67-1 mTOR kinase inhibitor The mammalian target of rapamycin (mTOR) is a serine-threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr MW: 308 D Formula: C16H16N6O Purity: >95% |
Cayman |
5 mg |
79 €
|
| Cay13687-1 |
CAS: 1038549-25-5 Rock kinase inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 443 D Formula: C25H25N5O3 Purity: >98% |
Cayman |
1 mg |
53 €
|
| Cay13687-10 |
CAS: 1038549-25-5 Rock kinase inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 443 D Formula: C25H25N5O3 Purity: >98% |
Cayman |
10 mg |
427 €
|
| Cay13687-25 |
CAS: 1038549-25-5 Rock kinase inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 443 D Formula: C25H25N5O3 Purity: >98% |
Cayman |
25 mg |
934 €
|
| Cay13687-5 |
CAS: 1038549-25-5 Rock kinase inhibitor Two Rho kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr MW: 443 D Formula: C25H25N5O3 Purity: >98% |
Cayman |
5 mg |
240 €
|
|
Cay13864-1 |
CaMKII inhibitor KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced a ... mehr MW: 537 D Formula: C26H29ClN2O4S - HCl Purity: >98% |
Cayman |
1 mg |
100 €
|
|
Cay13864-10 |
CaMKII inhibitor KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced a ... mehr MW: 537 D Formula: C26H29ClN2O4S - HCl Purity: >98% |
Cayman |
10 mg |
798 €
|
|
Cay13864-5 |
CaMKII inhibitor KN-93 is a selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. It inhibits histamine-induced a ... mehr MW: 537 D Formula: C26H29ClN2O4S - HCl Purity: >98% |
Cayman |
5 mg |
449 €
|
| Cay13964-1 |
CAS: 169939-93-9 PKCbeta1 / PKCbeta2 Inhibitor LY333531 is a selective and potent inhibitor of PKCbeta1 and PKCbeta2 (IC50 = 4.7 and 5.9 nM, respectively). For comparison, its IC50 values for PKC isoforms alpha, gamma, delta, epsilon, zeta, and eta are 360, 300, 250, 600, >100,000, and 52 nM, respecti ... mehr MW: 505 D Formula: C28H28N4O3-HCl Purity: >98% |
Cayman |
1 mg |
114 €
|
| Cay13964-5 |
CAS: 169939-93-9 PKCbeta1 / PKCbeta2 Inhibitor LY333531 is a selective and potent inhibitor of PKCbeta1 and PKCbeta2 (IC50 = 4.7 and 5.9 nM, respectively). For comparison, its IC50 values for PKC isoforms alpha, gamma, delta, epsilon, zeta, and eta are 360, 300, 250, 600, >100,000, and 52 nM, respecti ... mehr MW: 505 D Formula: C28H28N4O3-HCl Purity: >98% |
Cayman |
5 mg |
370 €
|
| Cay14006-1 |
CAS: 294646-77-8 CDK Inhibitor Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-CR8 is a second-generation analog of (R)-roscovitine (Item No. Cay10009569) that inhibits CDK1/cyclin B, CDK2/cyclin A ... mehr MW: 431 D Formula: C24H29N7O Purity: >98% |
Cayman |
1 mg |
64 €
|
| Cay14006-5 |
CAS: 294646-77-8 CDK Inhibitor Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-CR8 is a second-generation analog of (R)-roscovitine (Item No. Cay10009569) that inhibits CDK1/cyclin B, CDK2/cyclin A ... mehr MW: 431 D Formula: C24H29N7O Purity: >98% |
Cayman |
5 mg |
191 €
|
|
Cay14155-10 |
CAS: 479-41-4 GSK-3 inhibitor, CDK1 / 5 inhibitor Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase- ... mehr MW: 262 D Formula: C16H10N2O2 Purity: >98% |
Cayman |
10 mg |
100 €
|
|
Cay14155-25 |
CAS: 479-41-4 GSK-3 inhibitor, CDK1 / 5 inhibitor Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase- ... mehr MW: 262 D Formula: C16H10N2O2 Purity: >98% |
Cayman |
25 mg |
235 €
|
|
Cay14155-5 |
CAS: 479-41-4 GSK-3 inhibitor, CDK1 / 5 inhibitor Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase- ... mehr MW: 262 D Formula: C16H10N2O2 Purity: >98% |
Cayman |
5 mg |
52 €
|
|
Cay14155-50 |
CAS: 479-41-4 GSK-3 inhibitor, CDK1 / 5 inhibitor Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-inflammatory, anti-tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase- ... mehr MW: 262 D Formula: C16H10N2O2 Purity: >98% |
Cayman |
50 mg |
418 €
|
|
Cay14156-10 |
CAS: 1670-87-7 MAP kinase p38alpha / p38beta inhibitor SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested i ... mehr MW: 160 D Formula: C9H8N2O Purity: >97% |
Cayman |
10 mg |
65 €
|
|
Cay14156-25 |
CAS: 1670-87-7 MAP kinase p38alpha / p38beta inhibitor SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested i ... mehr MW: 160 D Formula: C9H8N2O Purity: >97% |
Cayman |
25 mg |
152 €
|
|
Cay14156-5 |
CAS: 1670-87-7 MAP kinase p38alpha / p38beta inhibitor SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-1, and MAPKAPK-2, when tested i ... mehr MW: 160 D Formula: C9H8N2O Purity: >97% |
Cayman |
5 mg |
41 €
|
|
Cay14185-10 |
CAS: 1223001-51-1 mTOR inhibitor Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr MW: 432 D Formula: C24H15F3N4O Purity: >98% |
Cayman |
10 mg |
176 €
|
|
Cay14185-25 |
CAS: 1223001-51-1 mTOR inhibitor Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr MW: 432 D Formula: C24H15F3N4O Purity: >98% |
Cayman |
25 mg |
413 €
|
|
Cay14185-5 |
CAS: 1223001-51-1 mTOR inhibitor Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr MW: 432 D Formula: C24H15F3N4O Purity: >98% |
Cayman |
5 mg |
110 €
|
|
Cay14428-1 |
CAS: 237430-03-4 CDK inhibitor, GSK-3beta inhibitor Alsterpaullone is a derivative of kenpaullone (Item No. Cay10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK-3beta). With slightly improved potency over kenpaullone, alsterpau ... mehr MW: 293 D Formula: C16H11N3O3 Purity: >98% |
Cayman |
1 mg |
64 €
|
|
Cay14428-5 |
CAS: 237430-03-4 CDK inhibitor, GSK-3beta inhibitor Alsterpaullone is a derivative of kenpaullone (Item No. Cay10010239), an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK-3beta). With slightly improved potency over kenpaullone, alsterpau ... mehr MW: 293 D Formula: C16H11N3O3 Purity: >98% |
Cayman |
5 mg |
288 €
|
|
Cay15015-1 |
CAS: 942487-16-3 Aurora kinase inhibitor, kinase inhibitor The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr MW: 474 D Formula: C23H25F3N6O2 Purity: >95% |
Cayman |
1 mg |
41 €
|
|
Cay15015-10 |
CAS: 942487-16-3 Aurora kinase inhibitor, kinase inhibitor The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr MW: 474 D Formula: C23H25F3N6O2 Purity: >95% |
Cayman |
10 mg |
305 €
|
|
Cay15015-5 |
CAS: 942487-16-3 Aurora kinase inhibitor, kinase inhibitor The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr MW: 474 D Formula: C23H25F3N6O2 Purity: >95% |
Cayman |
5 mg |
173 €
|
|
Cay15015-50 |
CAS: 942487-16-3 Aurora kinase inhibitor, kinase inhibitor The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr MW: 474 D Formula: C23H25F3N6O2 Purity: >95% |
Cayman |
50 mg |
711 €
|
|
Cay15018-10 |
CAS: 1255517-76-0 S6K1 inhibitor P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr MW: 390 D Formula: C19H21F3N6 Purity: >98% |
Cayman |
10 mg |
87 €
|
|
Cay15018-100 |
CAS: 1255517-76-0 S6K1 inhibitor P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr MW: 390 D Formula: C19H21F3N6 Purity: >98% |
Cayman |
100 mg |
696 €
|
|
Cay15018-25 |
CAS: 1255517-76-0 S6K1 inhibitor P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr MW: 390 D Formula: C19H21F3N6 Purity: >98% |
Cayman |
25 mg |
206 €
|
|
Cay15018-50 |
CAS: 1255517-76-0 S6K1 inhibitor P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-04708671 is a specific, cell-permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr MW: 390 D Formula: C19H21F3N6 Purity: >98% |
Cayman |
50 mg |
392 €
|
| Cay18218-10 |
CAS: 845714-00-3 Cdc7 kinase inhibitor CAY10572 is a potent inhibitor of Cdc7 kinase with an IC50 value of 10 nM in the presence of 1.5 µM ATP. At 10 µM, CAY10572 induces apoptotic cell death in multiple cancer cell types. CAY10572 also inhibits Cdk9. MW: 213 D Formula: C12H11N3O Purity: >98% |
Cayman |
10 mg |
371 €
|
| Cay18218-5 |
CAS: 845714-00-3 Cdc7 kinase inhibitor CAY10572 is a potent inhibitor of Cdc7 kinase with an IC50 value of 10 nM in the presence of 1.5 µM ATP. At 10 µM, CAY10572 induces apoptotic cell death in multiple cancer cell types. CAY10572 also inhibits Cdk9. MW: 213 D Formula: C12H11N3O Purity: >98% |
Cayman |
5 mg |
209 €
|
| Cay18218-50 |
CAS: 845714-00-3 Cdc7 kinase inhibitor CAY10572 is a potent inhibitor of Cdc7 kinase with an IC50 value of 10 nM in the presence of 1.5 µM ATP. At 10 µM, CAY10572 induces apoptotic cell death in multiple cancer cell types. CAY10572 also inhibits Cdk9. MW: 213 D Formula: C12H11N3O Purity: >98% |
Cayman |
50 mg |
1624 €
|
| Cay81590-0.1 |
CAS: 62996-74-1 PKC inhibitor Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. MW: 466 D Formula: C28H26N4O3 Purity: >98% |
Cayman |
100 µg |
53 €
|
| Cay81590-0.25 |
CAS: 62996-74-1 PKC inhibitor Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. MW: 466 D Formula: C28H26N4O3 Purity: >98% |
Cayman |
250 µg |
121 €
|
| Cay81590-0.5 |
CAS: 62996-74-1 PKC inhibitor Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. MW: 466 D Formula: C28H26N4O3 Purity: >98% |
Cayman |
500 µg |
213 €
|
| Cay81590-1 |
CAS: 62996-74-1 PKC inhibitor Staurosporine (Stsp) is potent inhibitor of protein kinase C (PKC) from rat brain, exhibiting an IC50 value of 2.7 nM. MW: 466 D Formula: C28H26N4O3 Purity: >98% |
Cayman |
1 mg |
320 €
|
| Cay9000890-1 |
CaMKII inhibitor KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca dependent kinase II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMK-II or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as ... mehr MW: 493 D Formula: C24H25ClN2O3S - HCl Purity: >98% |
Cayman |
1 mg |
99 €
|
| Cay9000890-10 |
CaMKII inhibitor KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca dependent kinase II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMK-II or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as ... mehr MW: 493 D Formula: C24H25ClN2O3S - HCl Purity: >98% |
Cayman |
10 mg |
798 €
|
| Cay9000890-5 |
CaMKII inhibitor KN-92 is an inactive derivative of KN-93, the selective inhibitor of Ca dependent kinase II (CaMKII). At concentrations up to 25 µM, KN-92 is ineffective at inhibiting CaMK-II or arresting cell growth of NIH 3T3 fibroblasts. It is intended to be used as ... mehr MW: 493 D Formula: C24H25ClN2O3S - HCl Purity: >98% |
Cayman |
5 mg |
449 €
|
| H1000.5 |
HA1077 , Highly Purified (1-(5-Isoquinolinesulfonyl) homopiperazine.2HCl)) CAS: 103745-39-7 Kinase inhibitor Molecular Formula: C14H17N3O2S.2HCl. Inhibits ROKa/ROCK II, PRK2, MSK1, Rsk2, PKA, p70 S6 Kinase, CaM Kinase and MLCK. MW: 364 D Formula: C14H19Cl2N3O2S.2HCl |
USBio |
5 mg |
231 €
|
| LKT-C0344.100 |
CAS: 121263-19-2 PKC inhibitor A highly specific inhibitor of PKC. which acts at the regulatory domain. IIt induces apoptosis in HL-60 human promyelocytic leukemia cells and human glioblastoma cells. MW: 790 D Purity: >98% |
LKT |
100 µg |
380 €
|
| LKT-C0346.10 |
CAS: 101932-71-2 Phosphatase inhibitor Calyculin A is a protein phosphatase inhibitor. It induces apoptosis in epithelial cell line, HeLa and KB, and human breast tumor cells. MW: 1.009 D Purity: >98% |
LKT |
10 µg |
232 €
|
| LKT-C0346.50 |
CAS: 101932-71-2 Phosphatase inhibitor Calyculin A is a protein phosphatase inhibitor. It induces apoptosis in epithelial cell line, HeLa and KB, and human breast tumor cells. MW: 1.009 D Purity: >98% |
LKT |
50 µg |
819 €
|
| LKT-C2818.1 |
CAS: 3895-92-9 PKC inhibitor A natural benzophenanthridine alkaloid. It inhibits protein kinase C and induces apoptosis in HL-60 human promyelocytic leukemia cells. MW: 383 D Purity: >98% |
LKT |
1 mg |
66 €
|
| LKT-C2818.5 |
CAS: 3895-92-9 PKC inhibitor A natural benzophenanthridine alkaloid. It inhibits protein kinase C and induces apoptosis in HL-60 human promyelocytic leukemia cells. MW: 383 D Purity: >98% |
LKT |
5 mg |
240 €
|
| LKT-C8500.1 |
CV-65 Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 270 D Purity: >98% |
LKT |
1 mg |
827 €
|
| LKT-C8500.100 |
CV-65 Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 270 D Purity: >98% |
LKT |
100 µg |
254 €
|
| LKT-C8501.1 |
Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 270 D Purity: >98% |
LKT |
1 mg |
827 €
|
| LKT-C8501.100 |
Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 270 D Purity: >98% |
LKT |
100 µg |
254 €
|
| LKT-C8502.1 |
CV-70 Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 298 D |
LKT |
1 mg |
636 €
|
| LKT-C8502.100 |
CV-70 Kinase inhibitor Diaza-anthracene compound known to inhibit ERK and JNK kinases. MW: 298 D |
LKT |
100 µg |
127 €
|
| LKT-D5868.10 |
CAS: 2859873-48-4 p38 MAP kinase inhibitor A pyrazole phenyl urea derivative is a reversible, competitive inhibitor of p38 MAP kinase. It interferes with ATP binding of p38. It also blocks tumor necrosis factor-alpha and IL-1beta synthesis. MW: 527 D |
LKT |
10 mg |
71 €
|
| LKT-D5868.100 |
CAS: 2859873-48-4 p38 MAP kinase inhibitor A pyrazole phenyl urea derivative is a reversible, competitive inhibitor of p38 MAP kinase. It interferes with ATP binding of p38. It also blocks tumor necrosis factor-alpha and IL-1beta synthesis. MW: 527 D |
LKT |
100 mg |
392 €
|
| LKT-D5868.25 |
CAS: 2859873-48-4 p38 MAP kinase inhibitor A pyrazole phenyl urea derivative is a reversible, competitive inhibitor of p38 MAP kinase. It interferes with ATP binding of p38. It also blocks tumor necrosis factor-alpha and IL-1beta synthesis. MW: 527 D |
LKT |
25 mg |
147 €
|
| LKT-H0001.25 |
CAS: 108930-17-2 PKC inhibitor The compound, H7, has been found to inhibit protein kinase C in rabbits. MW: 364 D Purity: >98% |
LKT |
25 mg |
220 €
|
| LKT-H0002.25 |
CAS: 113276-94-1 PKA inhibitor A potent inhibitor of PKA and cAMP. MW: 338 D Purity: >98% |
LKT |
25 mg |
226 €
|
| LKT-H0002.5 |
CAS: 113276-94-1 PKA inhibitor A potent inhibitor of PKA and cAMP. MW: 338 D Purity: >98% |
LKT |
5 mg |
79 €
|
| LKT-H0003.1 |
CAS: 127243-85-0 PKA inhibitor Selective potent inhibitor of cAMP-dependent protein kinase (PKA). MW: 446 D Purity: >98% |
LKT |
1 mg |
73 €
|
| LKT-H0003.5 |
CAS: 127243-85-0 PKA inhibitor Selective potent inhibitor of cAMP-dependent protein kinase (PKA). MW: 446 D Purity: >98% |
LKT |
5 mg |
184 €
|
| LKT-H9861.1 |
CAS: 548-04-9 PKC inhibitor Natural product from Hypericum perforatum (St. John's wort). It is an inhibitor of PKC and induces photsensitized apoptosis. It has antiviral and anticancer activities. A MAP kinase inhibitor. MW: 504 D Purity: >98% |
LKT |
1 mg |
220 €
|
| LKT-H9861.5 |
CAS: 548-04-9 PKC inhibitor Natural product from Hypericum perforatum (St. John's wort). It is an inhibitor of PKC and induces photsensitized apoptosis. It has antiviral and anticancer activities. A MAP kinase inhibitor. MW: 504 D Purity: >98% |
LKT |
5 mg |
746 €
|
| LKT-K0021.1 |
K252a CAS: 99533-80-9 Protein kinase inhibitor A potent protein kinase inhibitor that has shown promise fighting Met-driven proliferation of gastric carcinoma cells. MW: 467 D |
LKT |
1 mg |
638 €
|
| LKT-K0021.100 |
K252a CAS: 97161-97-2 Protein kinase inhibitor A potent protein kinase inhibitor that has shown promise fighting Met-driven proliferation of gastric carcinoma cells. MW: 467 D |
LKT |
100 µg |
121 €
|
| LKT-K0023.1 |
K252C CAS: 85753-43-1 PKC inhibitor K252c inhibits protein kinase C. MW: 311 D |
LKT |
1 mg |
140 €
|
| LKT-K0023.5 |
K252C CAS: 85753-43-1 PKC inhibitor K252c inhibits protein kinase C. MW: 311 D |
LKT |
5 mg |
588 €
|
| LKT-K1655.1 |
Kenpaullone CAS: 142273-20-9 CDK inhibitor A potent inhibitor of CDK1/cyclin B, that also inhibits CDK2/cyclin A, CDK2/cycline E, and CDK5/p25. It acts by competitive inhibition of ATP binding. MW: 327 D Purity: >95% |
LKT |
1 mg |
158 €
|
| LKT-K1655.5 |
Kenpaullone CAS: 142273-20-9 CDK inhibitor A potent inhibitor of CDK1/cyclin B, that also inhibits CDK2/cyclin A, CDK2/cycline E, and CDK5/p25. It acts by competitive inhibition of ATP binding. MW: 327 D Purity: >95% |
LKT |
5 mg |
636 €
|
| LKT-K7600.1 |
KT5720 CAS: 108068-98-0 Protein kinase inhibitor A protein kinase inhibitor that has been shown to reduce enzyme activity in INF- alpha thereby creating a potential pathway to treat tumors. MW: 537 D |
LKT |
1 mg |
1197 €
|
| LKT-K7600.100 |
KT5720 CAS: 108068-98-0 Protein kinase inhibitor A protein kinase inhibitor that has been shown to reduce enzyme activity in INF- alpha thereby creating a potential pathway to treat tumors. MW: 537 D |
LKT |
100 µg |
160 €
|
| LKT-K7602.1 |
KT5823 CAS: 126643-37-6 PKG inhibitor A K252 derivitive. MW: 481 D |
LKT |
1 mg |
1197 €
|
| LKT-K7602.100 |
KT5823 CAS: 126643-37-6 PKG inhibitor A K252 derivitive. MW: 481 D |
LKT |
100 µg |
160 €
|
| LKT-M0255.1 |
Manzamine A CAS: 104196-68-1 GSK-3beta inhibitor A carboline alkaloid isolated from the marine sponge Xestospongia ashmorica that acts as a GSK-3beta inhibitor. MW: 548 D |
LKT |
1 mg |
226 €
|
| LKT-M0255.5 |
Manzamine A CAS: 104196-68-1 GSK-3beta inhibitor A carboline alkaloid isolated from the marine sponge Xestospongia ashmorica that acts as a GSK-3beta inhibitor. MW: 548 D |
LKT |
5 mg |
881 €
|
| LKT-O4101.1 |
CAS: 78111-17-8 Phosphatase inhibitor Okadaic acid is a non-phorbol type tumor promoter. Potent inhibitor of protein phosphatases in numerous cell types. MW: 805 D Purity: >98% |
LKT |
1 mg |
2500 €
|
| LKT-O4101.100 |
CAS: 78111-17-8 Phosphatase inhibitor Okadaic acid is a non-phorbol type tumor promoter. Potent inhibitor of protein phosphatases in numerous cell types. MW: 805 D Purity: >98% |
LKT |
100 µg |
419 €
|
| LKT-O4101.25 |
CAS: 78111-17-8 Phosphatase inhibitor Okadaic acid is a non-phorbol type tumor promoter. Potent inhibitor of protein phosphatases in numerous cell types. MW: 805 D Purity: >98% |
LKT |
25 µg |
135 €
|
| LKT-O4101.50 |
CAS: 78111-17-8 Phosphatase inhibitor Okadaic acid is a non-phorbol type tumor promoter. Potent inhibitor of protein phosphatases in numerous cell types. MW: 805 D Purity: >98% |
LKT |
50 µg |
227 €
|
| LKT-O4102.1 |
Okadaic acid, ammonium salt CAS: 155716-06-6 Phosphatase inhibitor Ammonium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 822 D Purity: >98% |
LKT |
1 mg |
3583 €
|
| LKT-O4102.100 |
Okadaic acid, ammonium salt CAS: 155716-06-6 Phosphatase inhibitor Ammonium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 822 D Purity: >98% |
LKT |
100 µg |
464 €
|
| LKT-O4102.25 |
Okadaic acid, ammonium salt CAS: 155716-06-6 Phosphatase inhibitor Ammonium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 822 D Purity: >98% |
LKT |
25 µg |
147 €
|
| LKT-O4104.1 |
Okadaic acid, sodium salt CAS: 209266-80-8 Phosphatase inhibitor Sodium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 827 D Purity: >98% |
LKT |
1 mg |
3583 €
|
| LKT-O4104.100 |
Okadaic acid, sodium salt CAS: 209266-80-8 Phosphatase inhibitor Sodium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 827 D Purity: >98% |
LKT |
100 µg |
464 €
|
| LKT-O4104.25 |
Okadaic acid, sodium salt CAS: 209266-80-8 Phosphatase inhibitor Sodium salt form of okadaic acid, with somewhat greater stability after it is put into organic solvents. MW: 827 D Purity: >98% |
LKT |
25 µg |
158 €
|
| LKT-O4556.100 |
Olomoucine CAS: 101622-51-9 Protein kinase inhibitor Potent selective and competitive inhibitor of cyclin-dependent kinases. A MAP kinase inhibitor. MW: 298 D Purity: >98% |
LKT |
100 mg |
1767 €
|
| LKT-O4556.25 |
Olomoucine CAS: 101622-51-9 Protein kinase inhibitor Potent selective and competitive inhibitor of cyclin-dependent kinases. A MAP kinase inhibitor. MW: 298 D Purity: >98% |
LKT |
25 mg |
648 €
|
| LKT-O4556.5 |
Olomoucine CAS: 101622-51-9 Protein kinase inhibitor Potent selective and competitive inhibitor of cyclin-dependent kinases. A MAP kinase inhibitor. MW: 298 D Purity: >98% |
LKT |
5 mg |
149 €
|
| LKT-P0145.100 |
CAS: 6865-14-1 Protein kinase C PKC inhibitor A specific protein kinase C inhibitor. It inhibites 12-Otetra decanoyl phorbol-13-acetate (TPA) enhanced transformation in BALB/3T3 cells. MW: 436 D Purity: >98% |
LKT |
100 mg |
149 €
|
| LKT-P0145.500 |
CAS: 6865-14-1 Protein kinase C PKC inhibitor A specific protein kinase C inhibitor. It inhibites 12-Otetra decanoyl phorbol-13-acetate (TPA) enhanced transformation in BALB/3T3 cells. MW: 436 D Purity: >98% |
LKT |
500 mg |
446 €
|
| LKT-P1200.100 |
CAS: 212631-79-3 MEK inhibitor A potent and selective inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to induce apoptosis, has antiproliferative and antitumor activities. MW: 478 D |
LKT |
100 mg |
710 €
|
| LKT-P1200.25 |
CAS: 212631-79-3 MEK inhibitor A potent and selective inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to induce apoptosis, has antiproliferative and antitumor activities. MW: 478 D |
LKT |
25 mg |
343 €
|
| LKT-P1200.5 |
CAS: 212631-79-3 MEK inhibitor A potent and selective inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to induce apoptosis, has antiproliferative and antitumor activities. MW: 478 D |
LKT |
5 mg |
120 €
|
| LKT-P1202.100 |
PD325901 CAS: 391210-10-9 MEK inhibitor A potent inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to inhibit tumor cell growth, has antiangiogenic and antiproliferative activities. MW: 482 D |
LKT |
100 mg |
637 €
|
| LKT-P1202.25 |
PD325901 CAS: 391210-10-9 MEK inhibitor A potent inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to inhibit tumor cell growth, has antiangiogenic and antiproliferative activities. MW: 482 D |
LKT |
25 mg |
306 €
|
| LKT-P1202.5 |
PD325901 CAS: 391210-10-9 MEK inhibitor A potent inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to inhibit tumor cell growth, has antiangiogenic and antiproliferative activities. MW: 482 D |
LKT |
5 mg |
83 €
|
| LKT-S7600.1 |
CAS: 62996-74-1 PKC inhibitor A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentat ... mehr MW: 466 D Purity: >98% |
LKT |
1 mg |
56 €
|
| LKT-S7600.100 |
CAS: 62996-74-1 PKC inhibitor A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentat ... mehr MW: 466 D Purity: >98% |
LKT |
100 mg |
946 €
|
| LKT-S7600.25 |
CAS: 62996-74-1 PKC inhibitor A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentat ... mehr MW: 466 D Purity: >98% |
LKT |
25 mg |
334 €
|
| LKT-S7600.5 |
CAS: 62996-74-1 PKC inhibitor A protein kinase C inhibitor which induces apoptosis in many cell types. Experimental results obtained in a cell -free assay suggest that cytoplasmic proteins directly modulated by staurosporine may be involved in signaling the induction of DNA fragmentat ... mehr MW: 466 D Purity: >98% |
LKT |
5 mg |
195 €
|
|
LKT-T1298.100 |
CAS: 327036-89-5 GSK3 beta inhibitor An inhibitor of glycogen synthase kinase-3 (GSK3) beta, which was found to be a key intermediate in apoptotic signaling associated with neurodegenerative diseases such as Parkinson. Protect from light. Packaged under inert gas. MW: 222 D Purity: >98% |
LKT |
100 mg |
499 €
|
| LKT-T1298.25 |
CAS: 327036-89-5 GSK3 beta inhibitor An inhibitor of glycogen synthase kinase-3 (GSK3) beta, which was found to be a key intermediate in apoptotic signaling associated with neurodegenerative diseases such as Parkinson. MW: 222 D Purity: >98% |
LKT |
25 mg |
184 €
|
|
LKT-T1298.250 |
CAS: 327036-89-5 GSK3 beta inhibitor An inhibitor of glycogen synthase kinase-3 (GSK3) beta, which was found to be a key intermediate in apoptotic signaling associated with neurodegenerative diseases such as Parkinson. Protect from light. Packaged under inert gas. MW: 222 D Purity: >98% |
LKT |
250 mg |
723 €
|
| LKT-T1298.5 |
CAS: 327036-89-5 GSK3 beta inhibitor An inhibitor of glycogen synthase kinase-3 (GSK3) beta, which was found to be a key intermediate in apoptotic signaling associated with neurodegenerative diseases such as Parkinson. MW: 222 D Purity: >98% |
LKT |
5 mg |
50 €
|
| LKT-T5996.100 |
CAS: 639089-54-6 Aurora kinase inhibitor Tozasertib (VX680) is an Aurora kinase inhibitor found to suppress tumor growth. MW: 464 D |
LKT |
100 mg |
245 €
|
| LKT-T5996.25 |
CAS: 639089-54-6 Aurora kinase inhibitor Tozasertib (VX680) is an Aurora kinase inhibitor found to suppress tumor growth. MW: 464 D |
LKT |
25 mg |
83 €
|
| LKT-T5996.250 |
CAS: 639089-54-6 Aurora kinase inhibitor Tozasertib (VX680) is an Aurora kinase inhibitor found to suppress tumor growth. MW: 464 D |
LKT |
250 mg |
465 €
|
| M2865-17A.5 |
MEK1 Inhibitor (PD98059), CAS: 167869-21-8 Mw: 267,28. MW: 267 D Formula: C16H13NO3 |
USBio |
5 mg |
372 €
|
| M2865-17A.500 |
MEK1 Inhibitor (PD98059), CAS: 167869-21-8 Mw: 267,28. MW: 267 D Formula: C16H13NO3 |
USBio |
500 µg |
154 €
|
| M2865-17B.5 |
MEK1 Inhibitor (PD98059, 2+-amino-3+-methoxyflavone) CAS: 167869-21-8 MW: 267 kD Formula: C16H13NO3 |
USBio |
5 mg |
327 €
|
| M9848-02B.1 | Myosin Light Chain Kinase Inhibitor |
USBio |
1 mg |
277 €
|
| P9103-41M.1 |
Protein Kinase C, eta Inhibitor, Pseudosubstrate,, Highly Purified Mw: 2163. MW: 2.163 D |
USBio |
1 mg |
277 €
|
| P9103-41N.1 |
Protein Kinase C, eta Inhibitor, Pseudosubstrate, Myristoylated, Highly Purified Mw: 2374. MW: 2.374 D |
USBio |
1 mg |
277 €
|
| P9103-70.1 |
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Highly Purified Mw: 1718. MW: 1.718 D Formula: C76H128N30O16 |
USBio |
1 mg |
277 €
|
| P9103-71.1 |
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Myristoylated, Highly Purified Mw: 1928. MW: 1.928 D |
USBio |
1 mg |
277 €
|
| P9104-15.5 |
Protein Kinase Inhibitor H-7 (PKI), Molecular Biology Grade (1-(5-isoquinolinesulfonyl)-2- methylpiperazine dihydrochloride) CAS: 108930-17-2 Molecular Formula: C14H17N3O2S?2HCl. Mw: 364,3. MW: 364 D Formula: C14H17N3O2S.2HCl |
USBio |
5 mg |
231 €
|
| P9104-20.5 |
Protein Kinase Inhibitor H-8 (PKI), Molecular Biology Grade (N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide dihydrochloride) CAS: 84478-11-5 Molecular Formula: C12H15N3O2S.2HCl. Mw: 338,3. MW: 338 D Formula: C12H15N3O2S.2HCl |
USBio |
5 mg |
231 €
|
| P9104-22.25 |
Protein Kinase Inhibitor H-9 (PKI), Molecular Biology Grade (N-(2-aminoethyl)-5-isoquinolinesulfonamide dihydrochloride) CAS: 84468-17-7 Molecular Formula: C11H13N3O2S.2HCl. Mw: 324,23. MW: 324 D Formula: C11H13N3O2S.2HCl |
USBio |
25 mg |
394 €
|
| P9104-35.10 |
Protein Kinase Inhibitor H-89 (PKI), Molecular Biology Grade (N-(2-p-bromocinnamylaminoethyl]-5-isoquinolinesulfonamide) CAS: 127243-85-0 MW: 446 D Formula: C20H20N3O2SBr |
USBio |
10 mg |
394 €
|
| P9104-35.5 |
Protein Kinase Inhibitor H-89 (PKI), Molecular Biology Grade (N-(2-p-bromocinnamylaminoethyl]-5-isoquinolinesulfonamide) CAS: 127243-85-0 Molecular Formula: C20H20N3O2SBr . Mw: 446,4. MW: 446 D Formula: C20H20N3O2SBr |
USBio |
5 mg |
253 €
|
| P9104-40.5 |
Protein Kinase Inhibitor HA1004 (PKI), Molecular Biology Grade (N-(2-guanidinoethyl]-5-isoquinolinesulfonamide dihydrochloride) CAS: 92564-34-6 Molecular Formula: C12H15N5O2S.2HCl. Mw: 329,8. MW: 330 D Formula: C12H15N5O2S.2HCl |
USBio |
5 mg |
231 €
|
| P9104-65.5 |
Protein Kinase Inhibitor ML-7 (PKI), Molecular Biology Grade (1-(5-Iodonaphthalene-1-sulfonyl)-1H-hexahydro-1,4-diazepine hydrochloride) Molecular Formula: C15H17IN2O2S.HCl. Mw: 452,7. MW: 453 D Formula: C15H17IN2O2S.HCl |
USBio |
5 mg |
231 €
|
| P9104.25 |
Protein Kinase Inhibitor CKI-7 (PKI), Molecular Biology Grade (N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide) CAS: 120615-25-0 Molecular Formula: C11H12ClN3O2S. Mw: 285,74. MW: 286 D Formula: C11H12ClN3O2S |
USBio |
25 mg |
523 €
|
| P9104.5 |
Protein Kinase Inhibitor CKI-7 (PKI), Molecular Biology Grade (N-(2-aminoethyl)-5-chloro-isoquinoline-8-sulfonamide) CAS: 120615-25-0 Molecular Formula: C11H12ClN3O2S. Mw: 285,74. MW: 286 D Formula: C11H12ClN3O2S |
USBio |
5 mg |
240 €
|
| P9107-57.1 | Protein Phosphatase Inhibitor Set |
USBio |
1 kit |
614 €
|
| S0096-25.1 |
SAPK2, p38 MAPK Inhibitor (SB 202190) (Stress-activated Protein Kinase 2), Highly Purified CAS: 152121-30-7 Molecular Formula: C20H14FN3O. Mw: 331,3. MW: 331 D Formula: C20H14FN3O |
USBio |
1 mg |
362 €
|
| S0096-26.1 |
SAPK2, p38 Inhibitor (SB 203580) (Stress-activated Protein Kinase 2), Highly Purified CAS: 152121-47-6 Molecular Formula: C21H16FN3OS. Mw: 377,4. MW: 377 D Formula: C21H16FN3OS |
USBio |
1 mg |
362 €
|
| SIH-120A |
MAPKII Kinase Inhibitor (Hsp25 kinase inhibitor) MAPKAPK2 Inhibitor The MAPK (mitogen activated protein kinase) comprises a family of ubiquitous praline-directed, protein serine/threonine kinases which signal transduction pathways that control intracellular events including acute responses to hormones and major developmen ... mehr MW: 1.396 D Formula: C61H113N21O6 Purity: 95% |
StressMarq |
1 mg |
119 €
|
| SIH-253-1MG |
Staurosporine CAS: 62996-74-1 Protein kinase inhibitor Staurosporine is a broad spectrum protein kinase inhibitor with activities ranging from anti-fungal to anti-hypertensive. Staurosporine is a typical ATP-competitive kinase inhibitor that binds to many kinases with high affinity, but with little selectivit ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
StressMarq |
1 mg |
306 €
|
| SIH-253-250UG |
Staurosporine CAS: 62996-74-1 Protein kinase inhibitor Staurosporine is a broad spectrum protein kinase inhibitor with activities ranging from anti-fungal to anti-hypertensive. Staurosporine is a typical ATP-competitive kinase inhibitor that binds to many kinases with high affinity, but with little selectivit ... mehr MW: 466 D Formula: C28H26N4O3 Purity: >99% |
StressMarq |
250 µg |
126 €
|
|
SIH-371-10MG |
CAS: 103745-39-7 ROCK inhibitor Fasudil is a ROCK2 inhibitor with some action on PRK2 and MSK1 (IC50 values are 1.9 ?M, 4 ?M and 5 ?M respectively). It is also shown to inhibit RSK1, RSK2, PKA, AMPK and PKd1. It is also a calcium channel antagonist and vasodilator. MW: 327 D Formula: C14H17 N3O2S - HCl Purity: >98% |
StressMarq |
10 mg |
148 €
|
|
SIH-371-50MG |
CAS: 103745-39-7 ROCK inhibitor Fasudil is a ROCK2 inhibitor with some action on PRK2 and MSK1 (IC50 values are 1.9 ?M, 4 ?M and 5 ?M respectively). It is also shown to inhibit RSK1, RSK2, PKA, AMPK and PKd1. It is also a calcium channel antagonist and vasodilator. MW: 327 D Formula: C14H17 N3O2S - HCl Purity: >98% |
StressMarq |
50 mg |
578 €
|
|
VB2126 |
CAS: 82-08-6 Broad specifcity kinase inhibitor Broad specifcity kinase inhibitor. Autophagy activator. Solubility: Ethanol (2 mM), DMSO (100 mM). Appearance: Appearance: Orange to brown solid. MW: 517 D Formula: C30H28O8 |
Vivabioscience |
10 mg |
75 €
|
|
VB2148 |
CAS: 62996-74-1 Potent pan-specific protein kinase inhibitor Potent pan-specific protein kinase inhibitor. Apoptosis inducer. Autophagy activator. Solubility: DMSO (50 mg/mL) or ethanol (2 mg/mL, with warming). Appearance: Appearance: White to yellow powder. MW: 467 D Formula: C28H26N4O3 |
Vivabioscience |
1 mg |
105 €
|
|
VB2162 |
CAS: 129-56-6 JNK inhibitor JNK inhibitor. Autophagy inhibitor. Solubility: Ethanol (5 mM), DMSO (100 mM). Appearance: Appearance: White solid. MW: 220 D Formula: C14H8N2O |
Vivabioscience |
10 mg |
84 €
|
|
VB2176-0010 |
CAS: 22862-76-6 Protein synthesis inhibitor Protein synthesis inhibitor. JNK/SAPK activator. MAPK activator. Autophagy inhibitor. Solubility: Ethanol (100 mM), DMSO (100 mM). Appearance: Appearance: White waxy solid. MW: 265 D Formula: C14H19NO4 |
Vivabioscience |
10 mg |
56 €
|
|
VB2176-0050 |
CAS: 22862-76-6 Protein synthesis inhibitor Protein synthesis inhibitor. JNK/SAPK activator. MAPK activator. Autophagy inhibitor. Solubility: Ethanol (100 mM), DMSO (100 mM). Appearance: Appearance: White waxy solid. MW: 265 D Formula: C14H19NO4 |
Vivabioscience |
50 mg |
222 €
|
|
VB2748 |
CAS: 925681-41-0 Autophagy activator Autophagy activator. Akt Inhibitor. Solubility: Water. Appearance: Appearance: White solid. MW: 381 D Formula: C20H25ClN2O.HCl |
Vivabioscience |
5 mg |
278 €
|
|
VB2758 |
CAS: 7272-84-6 Autophagy activator Autophagy activator. Cell permeable, ATP competitive Rho kinase inhibitor. Solubility: DMSO, DMF, methanol. Appearance: Appearance: Off-white to beige solid. MW: 194 D Formula: C13H10N2 |
Vivabioscience |
5 mg |
84 €
|
|
VB2778 |
CAS: 93882-12-3 Autophagy inhibitor Autophagy inhibitor. cAMP analogue. cAMP / gAMP protein kinase activator. cAMP phosphodiesterase inhibitor. Solubility: Water (25 mg/mL). Appearance: Appearance: White solid. MW: 494 D Formula: C16H14ClN5NaO6PS |
Vivabioscience |
10 mg |
75 €
|
|
VB2782-0001 |
CAS: 280744-09-4 Autophagy inhibitor Autophagy inhibitor. GSK3 inhibitor. Solubility: DMSO (75mM). Appearance: Appearance: Orange solid. MW: 371 D Formula: C19H12Cl2N2O2 |
Vivabioscience |
1 mg |
75 €
|
|
VB2782-0005 |
CAS: 280744-09-4 Autophagy inhibitor Autophagy inhibitor. GSK3 inhibitor. Solubility: DMSO (75mM). Appearance: Appearance: Orange solid. MW: 371 D Formula: C19H12Cl2N2O2 |
Vivabioscience |
5 mg |
168 €
|
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