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003022.10 AZD8055
CAS: 1009298-​09-​2
mTOR kinase inhibitor Erklärungen der Abkürzungen ansehen.
A potent, selective, and orally bioavailable ATP-​competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. It inhibits the phosphorylation of mTORC1 substrates p70S6K and 4E-​BP1 as well as phosphorylation of the mTORC2 substrate AKT and downstream protein ... mehr
MW: 466 D
Formula: C25H31N5O4
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10 mg

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465 €

A1124-20B.1 Akt Inhibitor, Isozyme-​selective (1,3-​Dihydro-​1-​(1-​((4-​(6-​phenyl-​1H-​imidazo[4,5-​g]quinoxalin-​7-​yl)phenyl)methyl)-​4-​piperidinyl)-​2H-​benzimidazol-​2-​one, Akti-​1/2)
CAS: 612847-​09-​3
Purity: ~97% (HPLC)
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1 mg

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339 €

AG-CN2-0019-C100
CAS: 97161-​97-​2
Tyrosine kinase inhibitor Erklärungen der Abkürzungen ansehen.
Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
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100 µg

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108 €

AG-CN2-0019-M001
CAS: 97161-​97-​2
Tyrosine kinase inhibitor Erklärungen der Abkürzungen ansehen.
Isolated from Nonomuraea longicatena chiba. Antibiotic. PKC, PKA and PKG inhibitor. Shows neurotropic activity by inducing neurite outgrowth. Highly potent cell permeable CaM kinase and phosphorylase inhibitor. Tyrosine protein kinase inhibitor of the TRK ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
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1 mg

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495 €

AG-CN2-0022-C100
CAS: 62996-​74-​1
Protein kinase inhibitor, Apoptosis inducer Erklärungen der Abkürzungen ansehen.
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-​yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-​induced platelet aggregation. Potent, cell permeable, reversible, ATP-​competitive and ... mehr
MW: 466 D
Formula: C28H26N4O3
Purity: >99%
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100 µg

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50 €

AG-CN2-0022-C500
CAS: 62996-​74-​1
Protein kinase inhibitor, Apoptosis inducer Erklärungen der Abkürzungen ansehen.
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-​yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-​induced platelet aggregation. Potent, cell permeable, reversible, ATP-​competitive and ... mehr
MW: 466 D
Formula: C28H26N4O3
Purity: >99%
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500 µg

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105 €

AG-CN2-0022-M001
CAS: 62996-​74-​1
Protein kinase inhibitor, Apoptosis inducer Erklärungen der Abkürzungen ansehen.
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-​yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-​induced platelet aggregation. Potent, cell permeable, reversible, ATP-​competitive and ... mehr
MW: 466 D
Formula: C28H26N4O3
Purity: >99%
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1 mg

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143 €

AG-CN2-0022-M005
CAS: 62996-​74-​1
Protein kinase inhibitor, Apoptosis inducer Erklärungen der Abkürzungen ansehen.
Isolated from Streptomyces spiralis. Antibiotic. Antifungal and anti-​yeast activity. Inhibits platelet aggregation induced by collagen or ADP. Has no effect on thrombin-​induced platelet aggregation. Potent, cell permeable, reversible, ATP-​competitive and ... mehr
MW: 466 D
Formula: C28H26N4O3
Purity: >99%
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5 mg

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418 €

AG-CN2-0056-C025
CAS: 78111-​17-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >98%
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25 µg

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77 €

AG-CN2-0056-C100
CAS: 78111-​17-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >98%
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100 µg

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187 €

AG-CN2-0056-M001
CAS: 78111-​17-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >98%
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1 mg

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1320 €

AG-CN2-0057-C010
CAS: 87860-​39-​7
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Antibiotic. Anticancer compound. Anti-​fungal. Catalytic inhibitor of topoisomerase II (IC50 = 40 µM). Potent protein phosphatase 2A (PP2A) (IC50 = 1. 5 nM) and 4 (PP4) (IC50 = 3 nM) inhibitor. Weak protein phosphatase type 1 (PP1) inhibitor (IC50=131µM). ... mehr
MW: 452 D
Formula: C19H26O9PNa
Purity: >98%
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10 µg

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198 €

AG-CN2-0058-C025
CAS: 155716-​06-​6
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr
MW: 822 D
Formula: C44H67O13-NH4
Purity: >98%
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25 µg

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83 €

AG-CN2-0058-C100
CAS: 155716-​06-​6
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr
MW: 822 D
Formula: C44H67O13-NH4
Purity: >98%
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100 µg

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198 €

AG-CN2-0058-M001
CAS: 155716-​06-​6
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50= >1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful t ... mehr
MW: 822 D
Formula: C44H67O13-NH4
Purity: >98%
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1 mg

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1430 €

AG-CN2-0060-C025
CAS: 155751-​72-​7
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 843 D
Formula: C44H67O13-K
Purity: >98%
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25 µg

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83 €

AG-CN2-0060-C100
CAS: 155751-​72-​7
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 843 D
Formula: C44H67O13-K
Purity: >98%
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100 µg

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198 €

AG-CN2-0060-M001
CAS: 155751-​72-​7
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 843 D
Formula: C44H67O13-K
Purity: >98%
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1 mg

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1430 €

AG-CN2-0062-C025
CAS: 209266-​80-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 827 D
Formula: C44H67O13-Na
Purity: >98%
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25 µg

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83 €

AG-CN2-0062-C100
CAS: 209266-​80-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 827 D
Formula: C44H67O13-Na
Purity: >98%
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100 µg

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198 €

AG-CN2-0062-M001
CAS: 209266-​80-​8
Ser / Thr phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Non-​phorbol type tumor promoter. Reversible, potent and selective serine threonine protein phosphatase inhibitor. PP2A (IC50=0. 2-​1nM), PP1 (IC50=3-​15nM), PP2B (IC50=>1µM). Does not inhibit PP2C. Stimulates intracellular protein phosphorylation. Useful to ... mehr
MW: 827 D
Formula: C44H67O13-Na
Purity: >98%
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1 mg

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1430 €

AG-CN2-0068-C100
CAS: 75593-​17-​8
PKC Inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase C (PKC) inhibitor. Inhibits the ATP binding site. Cytotoxic and insecticidal. G2 DNA damage checkpoint inhibitor. Check point kinases 1 (Chk1) and 2 (Chk2) inhibitor. Does not inhibit ataxia-​telangiectasia mutated (ATM) or ATM-​Rad3-​related ... mehr
MW: 245 D
Formula: C11H11N5O2
Purity: >95%
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100 µg

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110 €

AG-CN2-0092-C250
CAS: 22467-​31-​8
PP2A inhibitor Erklärungen der Abkürzungen ansehen.
Isolated from Penicillium sp. Soluble in methanol, ethanol, acetone or DMSO. Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.
MW: 520 D
Formula: C26H32O11
Purity: >95%
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250 µg

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275 €

AG-CN2-0092-C500
CAS: 22467-​31-​8
PP2A inhibitor Erklärungen der Abkürzungen ansehen.
Isolated from Penicillium sp. Soluble in methanol, ethanol, acetone or DMSO. Mycotoxin. Potent and selective competitive protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. Antitumor agent. Antimetastatic.
MW: 520 D
Formula: C26H32O11
Purity: >95%
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500 µg

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462 €

AG-CN2-0093-C250
CAS: 156856-​30-​3
PP2A inhibitor Erklärungen der Abkürzungen ansehen.
Isolated from Streptomyces sp. MJ654-​NF4. Soluble in methanol, chloroform, ethyl acetate, DMSO or water. Potent and selective protein phosphatase 2A (PP2A) inhibitor. Cell adhesion inhibitor. Inhibits the adhesion of B16 melanoma cells to laminin and coll ... mehr
MW: 450 D
Formula: C21H32NaO7P
Purity: >75%
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250 µg

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275 €

AG-CN2-0097-M001
CAS: 85753-​43-​1
Indolocarbazole alkaloid antibiotic, PKC inhibitor Erklärungen der Abkürzungen ansehen.
Off-​white to yellow crystalline solid. Soluble in DMSO or methanol. Insoluble in water. Indolocarbazole alkaloid antibiotic., Potent cell permeable reversible and ATP-​competitive PKC (protein kinase C) inhibitor with 10-​fold selectivity over PKA (protein ... mehr
MW: 311 D
Formula: C20H13N3O
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1 mg

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88 €

AG-CN2-0097-M005
CAS: 85753-​43-​1
Indolocarbazole alkaloid antibiotic, PKC inhibitor Erklärungen der Abkürzungen ansehen.
Off-​white to yellow crystalline solid. Soluble in DMSO or methanol. Insoluble in water. Indolocarbazole alkaloid antibiotic., Potent cell permeable reversible and ATP-​competitive PKC (protein kinase C) inhibitor with 10-​fold selectivity over PKA (protein ... mehr
MW: 311 D
Formula: C20H13N3O
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5 mg

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352 €

AG-CN2-0111-M001
CAS: 35082-​49-​6
PKC Inhibitor Erklärungen der Abkürzungen ansehen.
Phytotoxin - Potent and specific PKC inhibitor. Competes for the phorbol binding site - Anticancer compound. Cytotoxic - Antiproliferative - Antiparasitic - Antimicrobial.
MW: 534 D
Formula: C29H26O10
Purity: >95%
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1 mg

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110 €

AG-CN2-0111-M005
CAS: 35082-​49-​6
PKC Inhibitor Erklärungen der Abkürzungen ansehen.
Phytotoxin - Potent and specific PKC inhibitor. Competes for the phorbol binding site - Anticancer compound. Cytotoxic - Antiproliferative - Antiparasitic - Antimicrobial.
MW: 534 D
Formula: C29H26O10
Purity: >95%
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5 mg

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440 €

AG-CN2-0424-M001
CAS: 524-​12-​9
IKKalpha  /  beta kinase activity inhibitor Erklärungen der Abkürzungen ansehen.
Yellow to amber crystalline powder. Soluble in DMSO or methanol. Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor, NF-​kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha, Antihepatotoxic. 5-​Lipoxy ... mehr
MW: 314 D
Formula: C16H10O7
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1 mg

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99 €

AG-CN2-0424-M005
CAS: 524-​12-​9
IKKalpha  /  beta kinase activity inhibitor Erklärungen der Abkürzungen ansehen.
Yellow to amber crystalline powder. Soluble in DMSO or methanol. Cell permeable, selective and irreversible IKKalpha and beta kinase activity inhibitor, NF-​kappaB inhibitor. Blocks phosphorylation and degradation of IkappaBalpha, Antihepatotoxic. 5-​Lipoxy ... mehr
MW: 314 D
Formula: C16H10O7
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5 mg

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297 €

AG-CN2-0430-C100
neu

CAS: 121263-​19-​2
Potent, specific cell permeable protein kinase C  ( PKC )  inhibitor Erklärungen der Abkürzungen ansehen.
Dark red to brown solid. Soluble in ethanol, methanol, DMSO or dimethylformamide. Poorly soluble in water. Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-​dependent, PKA, PKG, DAG kinase, phosphol ... mehr
MW: 790 D
Formula: C44H38O14
Purity: >95%
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100 µg

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88 €

AG-CN2-0430-M001
neu

CAS: 121263-​19-​2
Potent, specific cell permeable protein kinase C  ( PKC )  inhibitor Erklärungen der Abkürzungen ansehen.
Dark red to brown solid. Soluble in ethanol, methanol, DMSO or dimethylformamide. Poorly soluble in water. Potent and highly specific cell permeable protein kinase C (PKC) inhibitor. The inhibition of PKC is light-​dependent, PKA, PKG, DAG kinase, phosphol ... mehr
MW: 790 D
Formula: C44H38O14
Purity: >95%
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1 mg

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671 €

AG-CR1-0001-M010
CAS: 113276-​94-​1
PKA / PKG inhibitor, MLCK inhibitor Erklärungen der Abkürzungen ansehen.
Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Myosin light chain kinase (MLCK) inhibitor, Tool to study protein crystal structure-inhibitor interactions.
MW: 265 D
Formula: C12H15N3O2S . 2HCl
Purity: >98%
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10 mg

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44 €

AG-CR1-0001-M050
CAS: 113276-​94-​1
PKA / PKG inhibitor, MLCK inhibitor Erklärungen der Abkürzungen ansehen.
Potent cAMP- and cGMP-dependent protein kinase (PKA and PKG) inhibitor, Myosin light chain kinase (MLCK) inhibitor, Tool to study protein crystal structure-inhibitor interactions.
MW: 265 D
Formula: C12H15N3O2S . 2HCl
Purity: >98%
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50 mg

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176 €

AG-CR1-0002-M001
CAS: 127243-​85-​0
PKA / PKG inhibitor, PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent and selective cAMP-​ and cGMP-​dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-​dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) in ... mehr
MW: 446 D
Formula: C20H20BrN3O2S . 2HCl
Purity: >98%
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1 mg

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28 €

AG-CR1-0002-M005
CAS: 127243-​85-​0
PKA / PKG inhibitor, PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent and selective cAMP-​ and cGMP-​dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-​dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) in ... mehr
MW: 446 D
Formula: C20H20BrN3O2S . 2HCl
Purity: >98%
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5 mg

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55 €

AG-CR1-0002-M025
CAS: 127243-​85-​0
PKA / PKG inhibitor, PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent and selective cAMP-​ and cGMP-​dependent protein kinase (PKA and PKG) inhibitor, Protein kinase Cµ (PKCµ) inhibitor, Ca2+/calmodulin-​dependent protein kinase II inhibitor, Casein kinase I inhibitor, Myosin light chain kinase (MLCK) in ... mehr
MW: 446 D
Formula: C20H20BrN3O2S . 2HCl
Purity: >98%
Adipogen
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25 mg

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220 €

AG-CR1-0006-M001
CAS: 186692-​46-​6
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr
MW: 354 D
Formula: C19H26N6O
Purity: >98%
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1 mg

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33 €

AG-CR1-0006-M005
CAS: 186692-​46-​6
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr
MW: 354 D
Formula: C19H26N6O
Purity: >98%
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5 mg

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99 €

AG-CR1-0006-M050
CAS: 186692-​46-​6
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective inhibitor of CDKs, More potent than olomoucine, Inhibits CDK1/cyclin B kinase (IC50 = 450 nM) , CDK2 (IC50 = 700 nM) and CDK5/p35 (IC50 = 160 nM), Inhibits M phase promoting factor (MPF) kinase activity, Arrests human fibroblasts in ... mehr
MW: 354 D
Formula: C19H26N6O
Purity: >98%
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50 mg

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297 €

AG-CR1-0009-M001
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-​binding site of PKC, Anti-​inflammatory, Binds to P-​glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase k ... mehr
MW: 412 D
Formula: C25H24N4O2
Purity: >98%
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1 mg

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66 €

AG-CR1-0009-M005
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM), Competetive inhibitor for the ATP-​binding site of PKC, Anti-​inflammatory, Binds to P-​glycoprotein, Telomerase activity inhibitor, Potent glycogen synthase k ... mehr
MW: 412 D
Formula: C25H24N4O2
Purity: >98%
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5 mg

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193 €

AG-CR1-0010-M001 Bisindolylmaleimide II
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase C (PKC) inhibitor, Binds with reversed orientation to protein kinase A (PKA).
MW: 438 D
Formula: C27H26N4O2
Purity: >97% (mixture of 2 isomer
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1 mg

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66 €

AG-CR1-0010-M005 Bisindolylmaleimide II
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase C (PKC) inhibitor, Binds with reversed orientation to protein kinase A (PKA).
MW: 438 D
Formula: C27H26N4O2
Purity: >97% (mixture of 2 isomer
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5 mg

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193 €

AG-CR1-0025-M001
CAS: 284461-​73-​0
Raf kinase inhibitor Erklärungen der Abkürzungen ansehen.
Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review.
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
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1 mg

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33 €

AG-CR1-0025-M005
CAS: 284461-​73-​0
Raf kinase inhibitor Erklärungen der Abkürzungen ansehen.
Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review.
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
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5 mg

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99 €

AG-CR1-0025-M025
CAS: 284461-​73-​0
Raf kinase inhibitor Erklärungen der Abkürzungen ansehen.
Antitumor compound, Broad-spectrum kinase inhibitor, Raf kinase inhibitor, Apoptosis inducer, Cytostatic, Angiogenesis inhibitor, Review.
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
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25 mg

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248 €

AG-CR1-0028-M001
CAS: 152121-​30-​7
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.
MW: 331 D
Formula: C20H14FN3O
Purity: >97%
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1 mg

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36 €

AG-CR1-0028-M005
CAS: 152121-​30-​7
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.
MW: 331 D
Formula: C20H14FN3O
Purity: >97%
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5 mg

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88 €

AG-CR1-0028-M025
CAS: 152121-​30-​7
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.
MW: 331 D
Formula: C20H14FN3O
Purity: >97%
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25 mg

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341 €

AG-CR1-0029-M001
CAS: 212631-​79-​3
MEK inhibitor Erklärungen der Abkürzungen ansehen.
MEK (MAPKK) inhibitor, Potent and selective MAPK (ERK kinase 1, MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo), Suppresses activation of MAPK but does not block its activity, Antiproliferative, Causes cell-​cycle arrest in G1 phas ... mehr
MW: 478 D
Formula: C17H14ClF2IN2O2
Purity: >95%
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1 mg

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28 €

AG-CR1-0029-M005
CAS: 212631-​79-​3
MEK inhibitor Erklärungen der Abkürzungen ansehen.
MEK (MAPKK) inhibitor, Potent and selective MAPK (ERK kinase 1, MEK1) activation inhibitor (IC50 = 300 nM in vitro, IC50 = 2 nM in vivo), Suppresses activation of MAPK but does not block its activity, Antiproliferative, Causes cell-​cycle arrest in G1 phas ... mehr
MW: 478 D
Formula: C17H14ClF2IN2O2
Purity: >95%
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5 mg

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99 €

AG-CR1-0030-M001
CAS: 152121-​47-​6
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-​2 production inhibitor, SAPK/JNK inhibitor, COX-​1 and -​2 inhibitor, Raf-​1 activator, Apoptosis enhancer, Antiproliferati ... mehr
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
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1 mg

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42 €

AG-CR1-0030-M005
CAS: 152121-​47-​6
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-​2 production inhibitor, SAPK/JNK inhibitor, COX-​1 and -​2 inhibitor, Raf-​1 activator, Apoptosis enhancer, Antiproliferati ... mehr
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
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5 mg

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108 €

AG-CR1-0030-M025
CAS: 152121-​47-​6
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable, specific p38 MAP kinase inhibitor, Binds to the ATP binding site of p38 MAP kinase, T cell proliferation inhibitor, IL-​2 production inhibitor, SAPK/JNK inhibitor, COX-​1 and -​2 inhibitor, Raf-​1 activator, Apoptosis enhancer, Antiproliferati ... mehr
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
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25 mg

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319 €

AG-CR1-0035-M001
CAS: 676596-​65-​9
GSK-​3beta inhibitor Erklärungen der Abkürzungen ansehen.
Potent and ATP-competitive GSK-3beta (glycogen synthase kinase-3beta) inhibitor (IC50 = 18 nM).
MW: 328 D
Formula: C15H10BrN3O
Purity: >98%
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1 mg

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99 €

AG-CR1-0035-M005
CAS: 676596-​65-​9
GSK-​3beta inhibitor Erklärungen der Abkürzungen ansehen.
Potent and ATP-competitive GSK-3beta (glycogen synthase kinase-3beta) inhibitor (IC50 = 18 nM).
MW: 328 D
Formula: C15H10BrN3O
Purity: >98%
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5 mg

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396 €

AG-CR1-0036-M001
CAS: 237430-​03-​4
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-​tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-​3beta (glycogen synthase kinase-​3beta) inhibitor, Apoptosis inhibito ... mehr
MW: 293 D
Formula: C16H11N3O3
Purity: >98%
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1 mg

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77 €

AG-CR1-0036-M005
CAS: 237430-​03-​4
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent CDK1/cyclin B (IC50 = 35 nM) inhibitor, Anti-​tumor compound Potent inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50 = 200 nM), CDK5/p25 (IC50 = 40 nM), CDK5/p35 (IC50 = 40 nM), GSK-​3beta (glycogen synthase kinase-​3beta) inhibitor, Apoptosis inhibito ... mehr
MW: 293 D
Formula: C16H11N3O3
Purity: >98%
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5 mg

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308 €

AG-CR1-0039-M001
CAS: 294646-​77-​8
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
MW: 431 D
Formula: C24H29N7O
Purity: >98%
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1 mg

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50 €

AG-CR1-0039-M005
CAS: 294646-​77-​8
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Potent glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
MW: 431 D
Formula: C24H29N7O
Purity: 98%
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5 mg

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143 €

AG-CR1-0040-M001
CAS: 294646-​77-​8
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
MW: 431 D
Formula: C24H29N7O
Purity: >98%
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1 mg

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50 €

AG-CR1-0040-M005
CAS: 294646-​77-​8
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective cyclin-dependent kinase (CDK) 1, 2, 5, 7 and 9 inhibitor, Apoptosis inducer, Glycogen synthase kinase (GSK-3alpha/beta) inhibitor.
MW: 431 D
Formula: C24H29N7O
Purity: >98%
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5 mg

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143 €

AG-CR1-0049-M005
CAS: 337349-​54-​9
Necroptosis inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis inhibitor, Indirect RIP1 kinase inhibitor.
MW: 383 D
Formula: C19H17N3O2S2
Purity: >98%
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5 mg

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44 €

AG-CR1-0049-M025
CAS: 337349-​54-​9
Necroptosis inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis inhibitor, Indirect RIP1 kinase inhibitor.
MW: 383 D
Formula: C19H17N3O2S2
Purity: >98%
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25 mg

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176 €

AG-CR1-0065-M001
Ca2 dependent protein kinase II inhibitor Erklärungen der Abkürzungen ansehen.
Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor.
MW: 501 D
Formula: C26H29ClN2O4S . H3PO4
Purity: >98%
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1 mg

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94 €

AG-CR1-0065-M005
Ca2 dependent protein kinase II inhibitor Erklärungen der Abkürzungen ansehen.
Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor.
MW: 501 D
Formula: C26H29ClN2O4S . H3PO4
Purity: >98%
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5 mg

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319 €

AG-CR1-0065-M025
Ca2 dependent protein kinase II inhibitor Erklärungen der Abkürzungen ansehen.
Selective Ca2 dependent protein kinase II inhibitor, Insulin release inhibitor, Acid secretion inhibitor, G1 cell cycle arrest inducer, Apoptosis inducer, Ion channel inhibitor, ROS inducer, Androgen receptor inhibitor.
MW: 501 D
Formula: C26H29ClN2O4S . H3PO4
Purity: >98%
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25 mg

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798 €

AG-CR1-0071-M001
CAS: 3895-​92-​9
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-​dependent protein kinase or calcium/calmodulin-​dependent protein kinase, antiplatelet, anti-​inflammatory, antibacterial and antitumor compound, apoptosis ... mehr
MW: 383 D
Formula: C21H18ClNO
Purity: >98%
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1 mg

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33 €

AG-CR1-0071-M005
CAS: 3895-​92-​9
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-​dependent protein kinase or calcium/calmodulin-​dependent protein kinase, antiplatelet, anti-​inflammatory, antibacterial and antitumor compound, apoptosis ... mehr
MW: 383 D
Formula: C21H18ClNO
Purity: >98%
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5 mg

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72 €

AG-CR1-0071-M025
CAS: 3895-​92-​9
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable potent inhibitor of protein kinase C. Does not inhibit tyrosine protein kinases, cAMP-​dependent protein kinase or calcium/calmodulin-​dependent protein kinase, antiplatelet, anti-​inflammatory, antibacterial and antitumor compound, apoptosis ... mehr
MW: 383 D
Formula: C21H18ClNO
Purity: >98%
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25 mg

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286 €

AG-CR1-0087-M001
CAS: 169939-​93-​9
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Isozyme selective inhibitor of protein kinase Cb eta (PKCbeta) -​ PKCbeta-​I and PKCbeta-​II isozyme inhibitor -​ Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy -​ Anti-​cancer and anti-​angiogenic compound -​ Suppresse ... mehr
MW: 505 D
Formula: C28H28N4O3-HCl
Purity: >98%
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1 mg

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105 €

AG-CR1-0087-M005
CAS: 169939-​93-​9
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Isozyme selective inhibitor of protein kinase Cbeta (PKCbeta) -​ PKCbeta-​I and PKCbeta-​II isozyme inhibitor -​ Amelioriates diabetic retinopathy, diabetic peripheral neuropathy and diabetic nephropathy -​ Anti-​cancer and anti-​angiogenic compound -​ Suppresses ... mehr
MW: 505 D
Formula: C28H28N4O3-HCl
Purity: >98%
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5 mg

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319 €

AG-CR1-0109-M001
CAS: 151342-​35-​7
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo.
Formula: C28H28N4O2 . HCl
Purity: >98%
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1 mg

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94 €

AG-CR1-0109-M005
CAS: 151342-​35-​7
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo.
Formula: C28H28N4O2 . HCl
Purity: >98%
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5 mg

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308 €

AG-CR1-0110-M001
CAS: 176504-​36-​2
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki= 10 nM). Competitive inhibitor for the ATP-​binding site of PKC. Anti-​inflammatory. Binds to P-​glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase ki ... mehr
Formula: C25H24N4O2 . HCl
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1 mg

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66 €

AG-CR1-0110-M005
CAS: 176504-​36-​2
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki= 10 nM). Competitive inhibitor for the ATP-​binding site of PKC. Anti-​inflammatory. Binds to P-​glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase ki ... mehr
Formula: C25H24N4O2 . HCl
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5 mg

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193 €

AG-CR1-0111-M001
CAS: 138489-​18-​6
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-​3 (GSK-​3) inhibitor. Transcription inhibitor. Induces T ... mehr
Formula: C25H23N5O2S . CH4O3S
Purity: >98%
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1 mg

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66 €

AG-CR1-0111-M005
CAS: 138489-​18-​6
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-​3 (GSK-​3) inhibitor. Transcription inhibitor. Induces T ... mehr
Formula: C25H23N5O2S . CH4O3S
Purity: >98%
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5 mg

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193 €

AG-CR1-0112-M001
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
MW: 384 D
Formula: C23H20N4O2
Purity: >98%
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1 mg

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66 €

AG-CR1-0112-M005
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
MW: 384 D
Formula: C23H20N4O2
Purity: >98%
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5 mg

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193 €

AG-CR1-0113-M001
CAS: 131848-​97-​0
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils.
Formula: C26H24N4O2 . HCl
Purity: >98%
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1 mg

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94 €

AG-CR1-0113-M005
CAS: 131848-​97-​0
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2). Inhibits superoxide generation in human neutrophils.
Formula: C26H24N4O2 . HCl
Purity: >98%
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5 mg

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308 €

AG-CR1-0114-M001
CAS: 138516-​31-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas-​ and TRAIL-​mediated apoptosis. Inhibits T cell-​mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. I ... mehr
Formula: C24H22N4O2 . CH3COOH
Purity: >98%
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1 mg

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66 €

AG-CR1-0114-M005
CAS: 138516-​31-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Selective protein kinase C (PKC) inhibitor. Inhibits proliferation of cultured mouse epidermal keratinocytes. Enhances Fas-​ and TRAIL-​mediated apoptosis. Inhibits T cell-​mediated autoimmune diseases. Inhibits stimulation of insulin secretion by glucose. I ... mehr
Formula: C24H22N4O2 . CH3COOH
Purity: >98%
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5 mg

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193 €

AG-CR1-0152-M001
CAS: 119139-​23-​0
PKC / PKA inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
MW: 327 D
Formula: C20H13N3O2
Purity: >98%
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1 mg

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66 €

AG-CR1-0152-M005
CAS: 119139-​23-​0
PKC / PKA inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
MW: 327 D
Formula: C20H13N3O2
Purity: >98%
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5 mg

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193 €

AG-CR1-3503-M005
CAS: 327033-​36-​3
Pim-​1 / Pim-​2 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Selective inhibitor of Pim-​1 and Pim-​2 protein kinases, Inducer of G1 phase cell cycle arrest, Inducer of p27Kip1, Inducer of apoptosis through the mitochondrial pathway, Inhibitor of the mammalian target of rapamycin C1 (mTORC1) pathway, Downregulates c-​ ... mehr
MW: 273 D
Formula: C11H6F3NO2S
Purity: >95%
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5 mg

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88 €

AG-CR1-3520-M001
CAS: 1148118-​92-​6
Aurora A kinase inhibitor Erklärungen der Abkürzungen ansehen.
Soluble in DMSO (at least 10 mg/ml). Specific non-​ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, ... mehr
MW: 253 D
Formula: C15H11NO3
Purity: >98%
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1 mg

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88 €

AG-CR1-3520-M005
CAS: 1148118-​92-​6
Aurora A kinase inhibitor Erklärungen der Abkürzungen ansehen.
Soluble in DMSO (at least 10 mg/ml). Specific non-​ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects centrosome integrity, ... mehr
MW: 253 D
Formula: C15H11NO3
Purity: >98%
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5 mg

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352 €

AG-CR1-3564-M001
CAS: 146986-​50-​7
ROCK kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent, cell permeable, selective and ATP-​competitive Rho-​associated protein kinases inhibitor, including p160ROCK, ROCK-​II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr
Formula: C14H21N3O - 2HCl
Purity: >98%
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1 mg

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72 €

AG-CR1-3564-M005
CAS: 146986-​50-​7
ROCK kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent, cell permeable, selective and ATP-​competitive Rho-​associated protein kinases inhibitor, including p160ROCK, ROCK-​II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr
Formula: C14H21N3O - 2HCl
Purity: >98%
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5 mg

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286 €

AG-CR1-3564-M025
CAS: 146986-​50-​7
ROCK kinase inhibitor Erklärungen der Abkürzungen ansehen.
Potent, cell permeable, selective and ATP-​competitive Rho-​associated protein kinases inhibitor, including p160ROCK, ROCK-​II and PRK2 inhibitor. Tumor cell invasion and metastasis suppressor. Smooth muscle relaxant. Decreases liver fibrosis by hepatic stel ... mehr
Formula: C14H21N3O - 2HCl
Purity: >98%
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25 mg

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858 €

AG-CR1-3575-G001
CAS: 129-​46-​4
ATPase Inhibitor Erklärungen der Abkürzungen ansehen.
Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-​HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-​specific growth factors ... mehr
MW: 1.429 D
Formula: C51H34N6O23S6-6Na
Purity: >98%
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1 g

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418 €

AG-CR1-3575-M050
CAS: 129-​46-​4
ATPase Inhibitor Erklärungen der Abkürzungen ansehen.
Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-​HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-​specific growth factors ... mehr
MW: 1.429 D
Formula: C51H34N6O23S6-6Na
Purity: >98%
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50 mg

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44 €

AG-CR1-3575-M250
CAS: 129-​46-​4
ATPase Inhibitor Erklärungen der Abkürzungen ansehen.
Potent ATPase inhibitor. Potent competitive inhibitor of reverse transcriptase. Shows anti-​HIV activity. Anticancer compound. Protein kinase C (PKC) inhibitor. Potent inhibitor of melanoma heparanase and tumor cell metastasis. Non-​specific growth factors ... mehr
MW: 1.429 D
Formula: C51H34N6O23S6-6Na
Purity: >98%
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250 mg

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176 €

AG-CR1-3577-M005
CAS: 918505-​84-​7
B-​Raf  ( V600E )   /  c-​Raf-​1  ( Y340D / Y341D )  inhibitor Erklärungen der Abkürzungen ansehen.
Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.
MW: 413 D
Formula: C17H14ClF2N3O3S
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5 mg

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121 €

AG-CR1-3577-M025
CAS: 918505-​84-​7
B-​Raf  ( V600E )   /  c-​Raf-​1  ( Y340D / Y341D )  inhibitor Erklärungen der Abkürzungen ansehen.
Synthetic. Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines.
MW: 413 D
Formula: C17H14ClF2N3O3S
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25 mg

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363 €

AG-CR1-3579-M010
CAS: 68302-​57-​8
TBK1  /  IKKE inhibitor Erklärungen der Abkürzungen ansehen.
Soluble in DMSO or dimethylformamide. Antiallergic. Anti-​inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-​1 through S100A13. Inhibits FGF-​1 release. Binds to HSP90. Inhibits C-​terminal chaperone activity. Induces an increase in n ... mehr
MW: 298 D
Formula: C16H14N2O4
Purity: >98%
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10 mg

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83 €

AG-CR1-3579-M050
CAS: 68302-​57-​8
TBK1  /  IKKE inhibitor Erklärungen der Abkürzungen ansehen.
Soluble in DMSO or dimethylformamide. Antiallergic. Anti-​inflammatory. Antagonizes the angiogenic and mitogenic activity of FGF-​1 through S100A13. Inhibits FGF-​1 release. Binds to HSP90. Inhibits C-​terminal chaperone activity. Induces an increase in n ... mehr
MW: 298 D
Formula: C16H14N2O4
Purity: >98%
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50 mg

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330 €

Cay10005583-10
CAS: 129830-​38-​2
ROCK inhibitor Erklärungen der Abkürzungen ansehen.
Y-27632 is a potent, ATP-competitive inhibitor of Rho-associated protein kinases including p160ROCK (Ki = 140 nM) and ROCK-II (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM.
MW: 320 D
Formula: C14H21N3O · 2HCl
Purity: >98%
Cayman
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10 mg

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503 €

Cay10005583-5
CAS: 129830-​38-​2
ROCK inhibitor Erklärungen der Abkürzungen ansehen.
Y-27632 is a potent, ATP-competitive inhibitor of Rho-associated protein kinases including p160ROCK (Ki = 140 nM) and ROCK-II (IC50 = 800 nM). It also inhibits PRK2 with an IC50 value of 600 nM.
MW: 320 D
Formula: C14H21N3O · 2HCl
Purity: >98%
Cayman
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5 mg

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288 €

Cay10006727-1
CAS: 152121-​53-​4
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-​fold higher for extracellular signal-​regulated kinase (ERK) and >1,000-​fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr
MW: 360 D
Formula: C20H13FN4O2
Purity: >98%
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1 mg

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57 €

Cay10006727-10
CAS: 152121-​53-​4
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-​fold higher for extracellular signal-​regulated kinase (ERK) and >1,000-​fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr
MW: 360 D
Formula: C20H13FN4O2
Purity: >98%
Cayman
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10 mg

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159 €

Cay10006727-25
CAS: 152121-​53-​4
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-​fold higher for extracellular signal-​regulated kinase (ERK) and >1,000-​fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr
MW: 360 D
Formula: C20H13FN4O2
Purity: >98%
Cayman
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25 mg

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341 €

Cay10006727-5
CAS: 152121-​53-​4
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
PD 169316 is a selective inhibitor of p38 MAPK. It inhibits p38 MAPK with an IC50 of 89 nM, whereas the IC50s are >100-​fold higher for extracellular signal-​regulated kinase (ERK) and >1,000-​fold higher for protein kinase A (PKA) and PKCalpha. PD 169316 in ... mehr
MW: 360 D
Formula: C20H13FN4O2
Purity: >98%
Cayman
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5 mg

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90 €

Cay10007784-1
Akt inhibitor, PKB inhibitor Erklärungen der Abkürzungen ansehen.
Inositol-​1,3,4,5,6-​pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-​kinase/1-​phosphata ... mehr
MW: 690 D
Formula: C6H12O21P5 . 5Na
Purity: >98%
Cayman
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1 mg

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455 €

Cay10007784-100
Akt inhibitor, PKB inhibitor Erklärungen der Abkürzungen ansehen.
Inositol-​1,3,4,5,6-​pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-​kinase/1-​phosphata ... mehr
MW: 690 D
Formula: C6H12O21P5 . 5Na
Purity: >98%
Cayman
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100 µg

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57 €

Cay10007784-500
Akt inhibitor, PKB inhibitor Erklärungen der Abkürzungen ansehen.
Inositol-​1,3,4,5,6-​pentaphosphate (Ins(1,3,4,5,6)P5) is one of the many inositol phosphate isomers that act as small, soluble second messengers in the transmission of cellular signals. It can be interconverted with Ins(3,4,5,6)P4 by a 1-​kinase/1-​phosphata ... mehr
MW: 690 D
Formula: C6H12O21P5 . 5Na
Purity: >98%
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500 µg

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256 €

Cay10009569-10
CAS: 186692-​46-​6
CDK inhibitor, cyclin inhibitor Erklärungen der Abkürzungen ansehen.
(R)-Roscovitine is a potent inhibitor of CDK2/cyclin E with an IC50 value of 0.1 µM. It also inhibits CDK7/cyclin H, CDK5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively.
MW: 354 D
Formula: C19H26N6O
Purity: >98%
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10 mg

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276 €

Cay10009569-5
CAS: 186692-​46-​6
CDK inhibitor, cyclin inhibitor Erklärungen der Abkürzungen ansehen.
(R)-Roscovitine is a potent inhibitor of CDK2/cyclin E with an IC50 value of 0.1 µM. It also inhibits CDK7/cyclin H, CDK5/p35, and cell division cycle (cdc)/cyclin B with IC50 values of 0.49, 0.16, and 0.65 µM, respectively.
MW: 354 D
Formula: C19H26N6O
Purity: >98%
Cayman
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5 mg

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158 €

Cay10009644-1
CAS: 284461-​73-​0
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-​9006 is an inhibitor of Raf-​1 and B-​Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
Cayman
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1 mg

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32 €

Cay10009644-10
CAS: 284461-​73-​0
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-​9006 is an inhibitor of Raf-​1 and B-​Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
Cayman
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10 mg

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77 €

Cay10009644-5
CAS: 284461-​73-​0
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-​9006 is an inhibitor of Raf-​1 and B-​Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
Cayman
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5 mg

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51 €

Cay10009644-50
CAS: 284461-​73-​0
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. BAY 43-​9006 is an inhibitor of Raf-​1 and B-​Raf (IC50 = 6 and 22 nM, respectively), as well as several receptor tyrosine kinases, incl ... mehr
MW: 464 D
Formula: C21H16ClF3N4O3
Purity: >98%
Cayman
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50 mg

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300 €

Cay10010043-10
CAS: 933786-​58-​4
ERK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10561 is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM).
MW: 459 D
Formula: C22H17Cl2FN4O2
Purity: >98%
Cayman
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10 mg

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325 €

Cay10010043-5
CAS: 933786-​58-​4
ERK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10561 is a potent, ATP-competitive inhibitor of ERK2 (Ki = 2 nM). This compound is highly selective for ERK2 compared to other kinases such as PKA (Ki = 0.39 µM) and JNK3 (Ki = 4 µM).
MW: 459 D
Formula: C22H17Cl2FN4O2
Purity: >98%
Cayman
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5 mg

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186 €

Cay10010233-1
CAS: 32387-​96-​5
Akt1 translocation inhibitor Erklärungen der Abkürzungen ansehen.
CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain.
MW: 326 D
Formula: C21H14N2O2
Purity: >98%
Cayman
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1 g

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186 €

Cay10010233-100
CAS: 32387-​96-​5
Akt1 translocation inhibitor Erklärungen der Abkürzungen ansehen.
CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain.
MW: 326 D
Formula: C21H14N2O2
Purity: >98%
Cayman
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100 mg

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24 €

Cay10010233-250
CAS: 32387-​96-​5
Akt1 translocation inhibitor Erklärungen der Abkürzungen ansehen.
CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain.
MW: 326 D
Formula: C21H14N2O2
Purity: >98%
Cayman
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250 mg

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58 €

Cay10010233-500
CAS: 32387-​96-​5
Akt1 translocation inhibitor Erklärungen der Abkürzungen ansehen.
CAY10567 is an Akt1 translocation inhibitor. At a concentration of 12.5 µM, it prevents the translocation of Akt1 by apparently compromising the function of the PH domain.
MW: 326 D
Formula: C21H14N2O2
Purity: >98%
Cayman
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500 mg

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110 €

Cay10010236-100
CAS: 105637-​50-​1
Ser / Thr kinase inhibitor Erklärungen der Abkürzungen ansehen.
ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase.
MW: 361 D
Formula: C15H17ClN2O2S · HCl
Purity: >98%
Cayman
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100 mg

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313 €

Cay10010236-250
CAS: 105637-​50-​1
Ser / Thr kinase inhibitor Erklärungen der Abkürzungen ansehen.
ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase.
MW: 361 D
Formula: C15H17ClN2O2S · HCl
Purity: >98%
Cayman
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250 mg

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587 €

Cay10010236-50
CAS: 105637-​50-​1
Ser / Thr kinase inhibitor Erklärungen der Abkürzungen ansehen.
ML-9 was originally identified as a selective Ca2+calmodulin-dependent myosin light chain kinase inhibitor. ML-9 also inhibits PKB/Akt and other serine/threonine kinases including PKA, p90 S6, and MAP kinase.
MW: 361 D
Formula: C15H17ClN2O2S · HCl
Purity: >98%
Cayman
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50 mg

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209 €

Cay10010237-1
CAS: 35943-​35-​2
Akt inhibitor Erklärungen der Abkürzungen ansehen.
Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt.
MW: 320 D
Formula: C13H16N6O4
Purity: >98%
Cayman
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1 mg

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136 €

Cay10010237-10
CAS: 35943-​35-​2
Akt inhibitor Erklärungen der Abkürzungen ansehen.
Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt.
MW: 320 D
Formula: C13H16N6O4
Purity: >98%
Cayman
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10 mg

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1086 €

Cay10010237-5
CAS: 35943-​35-​2
Akt inhibitor Erklärungen der Abkürzungen ansehen.
Triciribine is a cell-permeable tricyclic nucleoside that inhibits the phosphorylation, activation, and signalling of Akt-1, -2, and -3. It does not inhibit PI3-Kinase or PDK1, the direct upstream activators of Akt.
MW: 320 D
Formula: C13H16N6O4
Purity: >98%
Cayman
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5 mg

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611 €

Cay10010239-10
CAS: 142273-​20-​9
CDK inhibitor, GSK-​3 beta inhibitor Erklärungen der Abkürzungen ansehen.
Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta).
MW: 327 D
Formula: C16H11BrN2O
Purity: >98%
Cayman
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10 mg

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362 €

Cay10010239-5
CAS: 142273-​20-​9
CDK inhibitor, GSK-​3 beta inhibitor Erklärungen der Abkürzungen ansehen.
Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta).
MW: 327 D
Formula: C16H11BrN2O
Purity: >98%
Cayman
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5 mg

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204 €

Cay10010239-50
CAS: 142273-​20-​9
CDK inhibitor, GSK-​3 beta inhibitor Erklärungen der Abkürzungen ansehen.
Kenpaullone is an ATP-competitive inhibitor of several cyclin-dependent kinases (CDKs) as well as glycogen synthase kinase 3 beta (GSK-3 beta).
MW: 327 D
Formula: C16H11BrN2O
Purity: >98%
Cayman
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50 mg

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1583 €

Cay10010240-10
CAS: 101622-​51-​9
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM).
MW: 298 D
Purity: >98%
Cayman
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10 mg

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130 €

Cay10010240-25
CAS: 101622-​51-​9
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM).
MW: 298 D
Purity: >98%
Cayman
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25 mg

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284 €

Cay10010240-5
CAS: 101622-​51-​9
CDK inhibitor Erklärungen der Abkürzungen ansehen.
Cdk inhibitor. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), CDK2/cyclin A (IC50 = 7 µM), CDK2/cyclin E (IC50 = 7 µM), CDK/p35 kinase (IC50 = 3 µM), and ERK1/p44 MAP kinase (IC50 = 25 µM).
MW: 298 D
Purity: >98%
Cayman
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5 mg

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73 €

Cay10010246-10
CAS: 280744-​09-​4
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway.
MW: 371 D
Formula: C19H12Cl2N2O2
Purity: >98%
Cayman
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10 mg

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130 €

Cay10010246-100
CAS: 280744-​09-​4
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway.
MW: 371 D
Formula: C19H12Cl2N2O2
Purity: >98%
Cayman
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100 mg

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958 €

Cay10010246-5
CAS: 280744-​09-​4
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway.
MW: 371 D
Formula: C19H12Cl2N2O2
Purity: >98%
Cayman
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5 mg

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68 €

Cay10010246-50
CAS: 280744-​09-​4
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3 alpha with an IC50 value of 34 nM (similar potency for GSK3 beta). SB 216763 protects primary neurons from death induced by the PI3-kinase pathway.
MW: 371 D
Formula: C19H12Cl2N2O2
Purity: >98%
Cayman
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50 mg

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548 €

Cay10010247-10
CAS: 264218-​23-​7
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 78 nM (similar potency for GSK3 beta and a Ki value of 31 nM).
MW: 359 D
Formula: C16H10ClN3O5
Purity: >98%
Cayman
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10 mg

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341 €

Cay10010247-5
CAS: 264218-​23-​7
GSK inhibitor Erklärungen der Abkürzungen ansehen.
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3alpha with an IC50 value of 78 nM (similar potency for GSK3 beta and a Ki value of 31 nM).
MW: 359 D
Formula: C16H10ClN3O5
Purity: >98%
Cayman
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5 mg

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195 €

Cay10010249-10
CAS: 113276-​94-​1
PKA inhibitor, PKG inhibitor Erklärungen der Abkürzungen ansehen.
H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively.
MW: 338 D
Formula: C12H15N3O2S · 2HCl
Purity: >98%
Cayman
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10 mg

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87 €

Cay10010249-25
CAS: 113276-​94-​1
PKA inhibitor, PKG inhibitor Erklärungen der Abkürzungen ansehen.
H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively.
MW: 338 D
Formula: C12H15N3O2S · 2HCl
Purity: >98%
Cayman
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25 mg

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195 €

Cay10010249-5
CAS: 113276-​94-​1
PKA inhibitor, PKG inhibitor Erklärungen der Abkürzungen ansehen.
H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively.
MW: 338 D
Formula: C12H15N3O2S · 2HCl
Purity: >98%
Cayman
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5 mg

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44 €

Cay10010249-50
CAS: 113276-​94-​1
PKA inhibitor, PKG inhibitor Erklärungen der Abkürzungen ansehen.
H-8, an isoquinolinesulfonamide PK inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for PKC and MLCK with Ki values of 1.2, 0.48, 15, and 68 µM, respectively.
MW: 338 D
Formula: C12H15N3O2S · 2HCl
Purity: >98%
Cayman
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50 mg

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346 €

Cay10010267-10
CAS: 354812-​17-​2
IKK2 inhibitor Erklärungen der Abkürzungen ansehen.
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes.
MW: 224 D
Formula: C9H8N2OS2
Purity: >98%
Cayman
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10 mg

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78 €

Cay10010267-25
CAS: 354812-​17-​2
IKK2 inhibitor Erklärungen der Abkürzungen ansehen.
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes.
MW: 224 D
Formula: C9H8N2OS2
Purity: >98%
Cayman
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25 mg

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183 €

Cay10010267-50
CAS: 354812-​17-​2
IKK2 inhibitor Erklärungen der Abkürzungen ansehen.
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2). It also reduces NF-kappaB-mediated expression of some genes.
MW: 224 D
Formula: C9H8N2OS2
Purity: >98%
Cayman
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50 mg

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325 €

Cay10010275-100
CAS: 520-​36-​5
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2).
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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100 mg

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201 €

Cay10010275-25
CAS: 520-​36-​5
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2).
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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25 mg

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56 €

Cay10010275-50
CAS: 520-​36-​5
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2).
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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50 mg

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106 €

Cay10010275-500
CAS: 520-​36-​5
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase II (CK2).
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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500 mg

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891 €

Cay10010301-10
CAS: 267654-​00-​2
CDK5 inhibitor, CDK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
MW: 260 D
Formula: C14H16N2OS
Purity: >95%
Cayman
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10 mg

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113 €

Cay10010301-25
CAS: 267654-​00-​2
CDK5 inhibitor, CDK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
MW: 260 D
Formula: C14H16N2OS
Purity: >95%
Cayman
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25 mg

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267 €

Cay10010301-5
CAS: 267654-​00-​2
CDK5 inhibitor, CDK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
MW: 260 D
Formula: C14H16N2OS
Purity: >95%
Cayman
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5 mg

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59 €

Cay10010301-50
CAS: 267654-​00-​2
CDK5 inhibitor, CDK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10554 is a potent inhibitor of Cdk5 and Cdk2, with IC50 values of 64 and 98 nM, respectively.
MW: 260 D
Formula: C14H16N2OS
Purity: >95%
Cayman
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50 mg

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473 €

Cay10010302-100
CAS: 53-​85-​0
CTD kinase inhibitor Erklärungen der Abkürzungen ansehen.
DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM).
MW: 319 D
Formula: C12H12Cl1N2O4
Purity: >98%
Cayman
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100 mg

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223 €

Cay10010302-250
CAS: 53-​85-​0
CTD kinase inhibitor Erklärungen der Abkürzungen ansehen.
DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM).
MW: 319 D
Formula: C12H12Cl1N2O4
Purity: >98%
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250 mg

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487 €

Cay10010302-50
CAS: 53-​85-​0
CTD kinase inhibitor Erklärungen der Abkürzungen ansehen.
DRB is a nucleoside analog that inhibits several carboxyl-terminal domain (CTD) kinases including casein kinase II (IC50 = 4-10 µM), cyclin-dependent kinase 7 (CDK7) (IC50 = 20 µM), CDK8 (IC50 = 20 µM), and CDK9 (IC50 = 3 µM).
MW: 319 D
Formula: C12H12Cl1N2O4
Purity: >98%
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50 mg

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125 €

Cay10010367-1
CAS: 208260-​29-​1
Raf-​1 inhibitor Erklärungen der Abkürzungen ansehen.
ZM 336372 is a potent ATP-​competitive inhibitor of Raf-​1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-​fold activation of Raf-​1 in whole cells. Activation of the Raf-​1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr
MW: 389 D
Formula: C23H23N3O3
Purity: >98%
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1 mg

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30 €

Cay10010367-10
CAS: 208260-​29-​1
Raf-​1 inhibitor Erklärungen der Abkürzungen ansehen.
ZM 336372 is a potent ATP-​competitive inhibitor of Raf-​1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-​fold activation of Raf-​1 in whole cells. Activation of the Raf-​1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr
MW: 389 D
Formula: C23H23N3O3
Purity: >98%
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10 mg

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241 €

Cay10010367-25
CAS: 208260-​29-​1
Raf-​1 inhibitor Erklärungen der Abkürzungen ansehen.
ZM 336372 is a potent ATP-​competitive inhibitor of Raf-​1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-​fold activation of Raf-​1 in whole cells. Activation of the Raf-​1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr
MW: 389 D
Formula: C23H23N3O3
Purity: >98%
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25 mg

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528 €

Cay10010367-5
CAS: 208260-​29-​1
Raf-​1 inhibitor Erklärungen der Abkürzungen ansehen.
ZM 336372 is a potent ATP-​competitive inhibitor of Raf-​1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-​fold activation of Raf-​1 in whole cells. Activation of the Raf-​1 signalling pathway using ZM 336372 in human carcinoid tumor cell ... mehr
MW: 389 D
Formula: C23H23N3O3
Purity: >98%
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5 mg

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136 €

Cay10010375-1
CAS: 24386-​93-​4
MAPK Inhibitor Erklärungen der Abkürzungen ansehen.
5-Iodotubercidin can inhibit a broad range of PKs including PKA (IC50 = 5-10 µM), phosphorylase kinase (IC50 = 5-10 µM), casein kinase I (IC50 = 0.4 µM) and II (IC50 = 10.9 µM), and PKC (IC50 = 0.4 µM) andERK2 (Ki = 525 nM).
MW: 392 D
Formula: C11H13IN4O4
Purity: >95%
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1 mg

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90 €

Cay10010375-5
CAS: 24386-​93-​4
MAPK Inhibitor Erklärungen der Abkürzungen ansehen.
5-Iodotubercidin can inhibit a broad range of PKs including PKA (IC50 = 5-10 µM), phosphorylase kinase (IC50 = 5-10 µM), casein kinase I (IC50 = 0.4 µM) and II (IC50 = 10.9 µM), and PKC (IC50 = 0.4 µM) andERK2 (Ki = 525 nM).
MW: 392 D
Formula: C11H13IN4O4
Purity: >95%
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5 mg

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302 €

Cay10010399-10
CAS: 152121-​30-​7
MAP kinases Inhibitor Erklärungen der Abkürzungen ansehen.
SB 202190 is a selective, potent, cell-​permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a r ... mehr
MW: 331 D
Formula: C20H14FN3O
Purity: >98%
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10 mg

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29 €

Cay10010399-25
CAS: 152121-​30-​7
MAP kinases Inhibitor Erklärungen der Abkürzungen ansehen.
SB 202190 is a selective, potent, cell-​permeable inhibitor of p38 MAP kinases, inhibiting p38alpha (SAPK2A, MAPK14) and p38beta (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively. When tested at 10 µM, SB 202190 has negligible effects on a r ... mehr
MW: 331 D
Formula: C20H14FN3O
Purity: >98%
Cayman
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25 mg

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56 €

Cay10010466-10
CAS: 129-​56-​6
JNK inhibitor Erklärungen der Abkürzungen ansehen.
SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells.,
MW: 220 D
Formula: C14H8N2O
Purity: >98%
Cayman
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10 mg

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81 €

Cay10010466-25
CAS: 129-​56-​6
JNK inhibitor Erklärungen der Abkürzungen ansehen.
SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells.,
MW: 220 D
Formula: C14H8N2O
Purity: >98%
Cayman
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25 mg

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194 €

Cay10010466-50
CAS: 129-​56-​6
JNK inhibitor Erklärungen der Abkürzungen ansehen.
SP 600125 is a potent and reversible inhibitor of JNK1, 2, and 3, with an IC50 value of 0.11 M. It is cell-permeable and dose-dependently inhibits c-Jun phosphorylation in cells.,
MW: 220 D
Formula: C14H8N2O
Purity: >98%
Cayman
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50 mg

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343 €

Cay10010541-10
CAS: 25695-​95-​8
PKC inhibitor Erklärungen der Abkürzungen ansehen.
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %.
MW: 299 D
Formula: C18H37NO2
Purity: >98%
Cayman
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10 mg

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220 €

Cay10010541-100
CAS: 25695-​95-​8
PKC inhibitor Erklärungen der Abkürzungen ansehen.
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %.
MW: 299 D
Formula: C18H37NO2
Purity: >98%
Cayman
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100 mg

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1624 €

Cay10010541-5
CAS: 25695-​95-​8
PKC inhibitor Erklärungen der Abkürzungen ansehen.
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %.
MW: 299 D
Formula: C18H37NO2
Purity: >98%
Cayman
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5 mg

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116 €

Cay10010541-50
CAS: 25695-​95-​8
PKC inhibitor Erklärungen der Abkürzungen ansehen.
L-threo-Sphingosine C-18, an analog of D-erythro-sphingosine, inhibits protein kinase C in mixed micelle assays with 50% inhibition at 2.2 mol %.
MW: 299 D
Formula: C18H37NO2
Purity: >98%
Cayman
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50 mg

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928 €

Cay10010556-10
CAS: 127243-​85-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b.
MW: 446 D
Formula: C20H20BrN3O2S
Purity: >98%
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10 mg

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101 €

Cay10010556-25
CAS: 127243-​85-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b.
MW: 446 D
Formula: C20H20BrN3O2S
Purity: >98%
Cayman
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25 mg

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240 €

Cay10010556-50
CAS: 127243-​85-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
H-89 is a potent, cell permeable inhibitor of PKA that demonstrates an IC50 value of 0.14 µM and a Ki value of 48 nM. It also inhibits S6K1, MSK1, ROCK-II, PKB alpha, and MAPKAP-K1b.
MW: 446 D
Formula: C20H20BrN3O2S
Purity: >98%
Cayman
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50 mg

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427 €

Cay10010559-100
CAS: 203911-​27-​7
ROCK-​II inhibitor Erklärungen der Abkürzungen ansehen.
HA-1077 is a potent inhibitor of ROCK-II and additionally inhibits Protein Kinase C-related Kinase 2 (PRK2), Mitogen- and Stress-Activated Protein Kinase (MSK1), and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively.
MW: 364 D
Formula: C14H17N3O2S . 2HCl
Purity: >98%
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100 mg

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747 €

Cay10010559-50
CAS: 203911-​27-​7
ROCK-​II inhibitor Erklärungen der Abkürzungen ansehen.
HA-1077 is a potent inhibitor of ROCK-II and additionally inhibits Protein Kinase C-related Kinase 2 (PRK2), Mitogen- and Stress-Activated Protein Kinase (MSK1), and MAPKAP-K1b with IC50 values of 1.9, 4, 5, and 15 µM, respectively.
MW: 364 D
Formula: C14H17N3O2S . 2HCl
Purity: >98%
Cayman
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50 mg

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427 €

Cay10010965-100
CAS: 126643-​37-​6
PKG inhibitor Erklärungen der Abkürzungen ansehen.
KT 5823 is a potent, selective inhibitor of PKG (in vitro IC50 = 234 nM). It is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells.
MW: 495 D
Formula: C29H25N3O5
Purity: >95%
Cayman
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100 µg

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117 €

Cay10010965-250
CAS: 126643-​37-​6
PKG inhibitor Erklärungen der Abkürzungen ansehen.
KT 5823 is a potent, selective inhibitor of PKG (in vitro IC50 = 234 nM). It is cell-permeable and is often used in intact cells to assess the role of PKG in signaling, although there are cases where it poorly inhibits PKG in cells.
MW: 495 D
Formula: C29H25N3O5
Purity: >95%
Cayman
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250 µg

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260 €

Cay10011011-0.05
CAS: 108068-​98-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta.
MW: 537 D
Formula: C32H31N3O5
Purity: >98%
Cayman
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50 µg

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80 €

Cay10011011-0.1
CAS: 108068-​98-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta.
MW: 537 D
Formula: C32H31N3O5
Purity: >98%
Cayman
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100 µg

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152 €

Cay10011011-0.25
CAS: 108068-​98-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta.
MW: 537 D
Formula: C32H31N3O5
Purity: >98%
Cayman
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250 µg

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361 €

Cay10011011-0.5
CAS: 108068-​98-​0
PKA inhibitor Erklärungen der Abkürzungen ansehen.
Blocks Protein kinase A (PKA) signaling through competitive inhibition of ATP with a Ki value of 60 nM. Non-specific effects of KT 5720 include inhibition of phosphorylase kinase, PDK1, MEK, MSK1, PKBa, and GSK3beta.
MW: 537 D
Formula: C32H31N3O5
Purity: >98%
Cayman
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500 µg

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640 €

Cay10011247-10
CAS: 140651-​18-​9
CDK9 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E.
MW: 218 D
Formula: C9H10N6O
Purity: >95%
Cayman
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10 mg

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176 €

Cay10011247-5
CAS: 140651-​18-​9
CDK9 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E.
MW: 218 D
Formula: C9H10N6O
Purity: >95%
Cayman
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5 mg

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100 €

Cay10011247-50
CAS: 140651-​18-​9
CDK9 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10574 is a potent, selective inhibitor of Cyclin-dependent kinase 9 (CDK9) in vitro with an IC50 value of 0.35 µM. It is also a competitive inhibitor of CDK2-cyclin E.
MW: 218 D
Formula: C9H10N6O
Purity: >95%
Cayman
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50 mg

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771 €

Cay10011248-10
CAS: 916985-​21-​2
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM.
MW: 487 D
Formula: C22H21N3O6S2
Purity: >95%
Cayman
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10 mg

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232 €

Cay10011248-25
CAS: 916985-​21-​2
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM.
MW: 487 D
Formula: C22H21N3O6S2
Purity: >95%
Cayman
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25 mg

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508 €

Cay10011248-5
CAS: 916985-​21-​2
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10575 is a benzimidazole analog that inhibits IKK-epsilon with an IC50 value of 15.8 µM.
MW: 487 D
Formula: C22H21N3O6S2
Purity: >95%
Cayman
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5 mg

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131 €

Cay10011249-10
CAS: 862812-​98-​4
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta.
MW: 469 D
Formula: C22H19N3O5S2
Purity: >95%
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10 mg

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334 €

Cay10011249-5
CAS: 862812-​98-​4
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta.
MW: 469 D
Formula: C22H19N3O5S2
Purity: >95%
Cayman
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5 mg

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188 €

Cay10011249-50
CAS: 862812-​98-​4
IKKepsilon inhibitor Erklärungen der Abkürzungen ansehen.
CAY10576 is a benzimidazole analog that selectively inhibits IKK-epsilon with an IC50 value of 40 nM and is essentially inactive at IKK-alpha and IKK-beta.
MW: 469 D
Formula: C22H19N3O5S2
Purity: >95%
Cayman
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50 mg

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1462 €

Cay10011250-10
CAS: 278603-​08-​0
eEF-​2K inhibitor Erklärungen der Abkürzungen ansehen.
In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM).
MW: 524 D
Formula: C27H45IN2
Purity: >95%
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10 mg

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251 €

Cay10011250-5
CAS: 278603-​08-​0
eEF-​2K inhibitor Erklärungen der Abkürzungen ansehen.
In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM).
MW: 524 D
Formula: C27H45IN2
Purity: >95%
Cayman
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5 mg

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142 €

Cay10011250-50
CAS: 278603-​08-​0
eEF-​2K inhibitor Erklärungen der Abkürzungen ansehen.
In mammalian cells, NH125 strongly inhibits eEF-2K (IC50 = 60 nM), with weaker effects on protein kinase C (IC50=7.5 µM), protein kinase A (IC50=80 µM), and calmodulin-dependent kinase II (IC50=100 µM).
MW: 524 D
Formula: C27H45IN2
Purity: >95%
Cayman
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50 mg

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1096 €

Cay10011251-10
CAS: 601514-​19-​6
GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.
MW: 318 D
Formula: C18H14N4O2
Purity: >90%
Cayman
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10 mg

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334 €

Cay10011251-25
CAS: 601514-​19-​6
GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.
MW: 318 D
Formula: C18H14N4O2
Purity: >90%
Cayman
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25 mg

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731 €

Cay10011251-5
CAS: 601514-​19-​6
GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
TWS119 potently inhibits GSK3beta with an IC50 value of 30 nM. At 400 nM, TWS119 induces neurogenesis in murine embryonic stem cells making it a useful tool to regulate stem cell self-renewal and differentiation.
MW: 318 D
Formula: C18H14N4O2
Purity: >90%
Cayman
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5 mg

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188 €

Cay10011255-10
CAS: 51726-​83-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases.
MW: 239 D
Formula: C14H9NO3
Purity: >95%
Cayman
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10 mg

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121 €

Cay10011255-5
CAS: 51726-​83-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases.
MW: 239 D
Formula: C14H9NO3
Purity: >95%
Cayman
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5 mg

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68 €

Cay10011255-50
CAS: 51726-​83-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
NSC 210902 inhibits CK2 with an IC50 value of 1 µM and competitively inhibits binding of ATP with a Ki value of 0.28 µM. NSC 210902 is selective for CK2 as it only minimally inhibits the activities of other protein kinases.
MW: 239 D
Formula: C14H9NO3
Purity: >95%
Cayman
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50 mg

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528 €

Cay10011256-10
CAS: 300675-​28-​9
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM.
MW: 258 D
Formula: C10H5Cl2NO3
Purity: >95%
Cayman
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10 mg

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121 €

Cay10011256-5
CAS: 300675-​28-​9
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM.
MW: 258 D
Formula: C10H5Cl2NO3
Purity: >95%
Cayman
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5 mg

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68 €

Cay10011256-50
CAS: 300675-​28-​9
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Casein kinase 2 (CK2) is a serine/threonine-selective protein kinase involved in many signal transduction pathways. CAY10577 inhibits CK2 with an IC50 value of 0.8 µM.
MW: 258 D
Formula: C10H5Cl2NO3
Purity: >95%
Cayman
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50 mg

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528 €

Cay10011264-10
CAS: 19231-​60-​8
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1).
MW: 708 D
Formula: C10H3I4NO4
Purity: >95%
Cayman
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10 mg

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121 €

Cay10011264-25
CAS: 19231-​60-​8
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1).
MW: 708 D
Formula: C10H3I4NO4
Purity: >95%
Cayman
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25 mg

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264 €

Cay10011264-5
CAS: 19231-​60-​8
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10578 is a potent inhibitor of CK2 with an IC50 value of 0.3 µM. This compound is ATP competitive, displaying a Ki value of 0.2 µM and only minimally inhibits the activities of other protein kinases (e.g., GSK3, CDK5, and MSK1).
MW: 708 D
Formula: C10H3I4NO4
Purity: >95%
Cayman
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5 mg

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68 €

Cay10011490-100
CAS: 78111-​17-​8
PP1 PP2A PP3 inhibitor Erklärungen der Abkürzungen ansehen.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-​50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >95%
Cayman
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100 µg

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113 €

Cay10011490-25
CAS: 78111-​17-​8
PP1 PP2A PP3 inhibitor Erklärungen der Abkürzungen ansehen.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-​50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >95%
Cayman
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25 µg

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31 €

Cay10011490-50
CAS: 78111-​17-​8
PP1 PP2A PP3 inhibitor Erklärungen der Abkürzungen ansehen.
Okadaic acid is a marine sponge toxin which potently inhibits certain serine/threonine protein phosphatases. This cell permeable inhibitor targets the multiple isoforms of PP1 (IC50 values ranging from 10-​50 nM), both isoforms of PP2A (IC50 = 0.5 nM), and ... mehr
MW: 805 D
Formula: C44H68O13
Purity: >95%
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50 µg

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59 €

Cay10398-1
CAS: 300801-​52-​9
Cdc2 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Specific ATP-competitive inhibitor of Cdc2-like kinase.
MW: 249 D
Formula: C13H15NO2S
Purity: >95%
Cayman
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1 mg

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21 €

Cay10398-10
CAS: 300801-​52-​9
Cdc2 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Specific ATP-competitive inhibitor of Cdc2-like kinase.
MW: 249 D
Formula: C13H15NO2S
Purity: >95%
Cayman
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10 mg

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167 €

Cay10398-25
CAS: 300801-​52-​9
Cdc2 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Specific ATP-competitive inhibitor of Cdc2-like kinase.
MW: 249 D
Formula: C13H15NO2S
Purity: >95%
Cayman
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25 mg

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365 €

Cay10398-5
CAS: 300801-​52-​9
Cdc2 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Specific ATP-competitive inhibitor of Cdc2-like kinase.
MW: 249 D
Formula: C13H15NO2S
Purity: >95%
Cayman
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5 mg

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94 €

Cay10527-25
CAS: 337349-​54-​9
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 383 D
Formula: C19H17N3O2S2
Purity: >98%
Cayman
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25 mg

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183 €

Cay10527-5
CAS: 337349-​54-​9
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 383 D
Formula: C19H17N3O2S2
Purity: >98%
Cayman
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5 mg

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41 €

Cay10876-10
CAS: 871361-​88-​5
AKT inhibitor Erklärungen der Abkürzungen ansehen.
SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt.
MW: 276 D
Formula: C18H16N2O
Purity: >98%
Cayman
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10 mg

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66 €

Cay10876-100
CAS: 871361-​88-​5
AKT inhibitor Erklärungen der Abkürzungen ansehen.
SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt.
MW: 276 D
Formula: C18H16N2O
Purity: >98%
Cayman
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100 mg

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487 €

Cay10876-25
CAS: 871361-​88-​5
AKT inhibitor Erklärungen der Abkürzungen ansehen.
SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt.
MW: 276 D
Formula: C18H16N2O
Purity: >98%
Cayman
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25 mg

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157 €

Cay10876-5
CAS: 871361-​88-​5
AKT inhibitor Erklärungen der Abkürzungen ansehen.
SC-66 is an allosteric inhibitor of Akt that facilitates both ubiquitination and deactivation of Akt.
MW: 276 D
Formula: C18H16N2O
Purity: >98%
Cayman
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5 mg

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35 €

Cay10997-10
CAS: 1222998-​36-​8
mTor inhibitor Erklärungen der Abkürzungen ansehen.
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-​fold selectivity for mTOR over PI3Kalpha and other PI3K-​like kinases, including ATM, DNA-​PK, and hVps34, as well as 450 other p ... mehr
MW: 607 D
Formula: C35H28F3N5O2
Purity: >95%
Cayman
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10 mg

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139 €

Cay10997-25
CAS: 1222998-​36-​8
mTor inhibitor Erklärungen der Abkürzungen ansehen.
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-​fold selectivity for mTOR over PI3Kalpha and other PI3K-​like kinases, including ATM, DNA-​PK, and hVps34, as well as 450 other p ... mehr
MW: 607 D
Formula: C35H28F3N5O2
Purity: >95%
Cayman
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25 mg

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313 €

Cay10997-50
CAS: 1222998-​36-​8
mTor inhibitor Erklärungen der Abkürzungen ansehen.
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-​fold selectivity for mTOR over PI3Kalpha and other PI3K-​like kinases, including ATM, DNA-​PK, and hVps34, as well as 450 other p ... mehr
MW: 607 D
Formula: C35H28F3N5O2
Purity: >95%
Cayman
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50 mg

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512 €

Cay11020-1
CAS: 137592-​45-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A
MW: 438 D
Formula: C27H26N4O2
Purity: >97%
Cayman
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1 mg

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52 €

Cay11020-5
CAS: 137592-​45-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase C (PKC) inhibitor. Binds with reversed orientation to protein kinase A
MW: 438 D
Formula: C27H26N4O2
Purity: >97%
Cayman
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5 mg

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162 €

Cay11072-1
CAS: 137592-​43-​9
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other p ... mehr
MW: 384 D
Formula: C23H20N4O2
Purity: >98%
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1 mg

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52 €

Cay11072-5
CAS: 137592-​43-​9
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide III was developed as a protein kinase C (PKC) inhibitor with structural similarity to the nonspecific PKC inhibitor staurosporine. At 1 µM, bisindolylmaleimide III inhibits 93% of PKCalpha kinase activity and also inhibits many other p ... mehr
MW: 384 D
Formula: C23H20N4O2
Purity: >98%
Cayman
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5 mg

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162 €

Cay11073-1
CAS: 145333-​02-​4
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-0432
MW: 489 D
Formula: C28H28N4O2 HCl
Purity: >98%
Cayman
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1 mg

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75 €

Cay11073-5
CAS: 145333-​02-​4
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-0432
MW: 489 D
Formula: C28H28N4O2 HCl
Purity: >98%
Cayman
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5 mg

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340 €

Cay11314-1
CAS: 3895-​92-​9
Inhibitor of protein kinase C Erklärungen der Abkürzungen ansehen.
Chelerythrine chloride is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-​dependent protein kinase, or calcium/calmodulin-​dependent protein kinase. Chelerythrine also inhibits Bcl ... mehr
MW: 383 D
Formula: C21H18NO4 Cl
Purity: >98%
Cayman
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1 mg

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29 €

Cay11314-5
CAS: 3895-​92-​9
Inhibitor of protein kinase C Erklärungen der Abkürzungen ansehen.
Chelerythrine chloride is a potent, cell permeable inhibitor of protein kinase C (IC50 = 660 nM) that does not inhibit tyrosine protein kinases, cAMP-​dependent protein kinase, or calcium/calmodulin-​dependent protein kinase. Chelerythrine also inhibits Bcl ... mehr
MW: 383 D
Formula: C21H18NO4 Cl
Purity: >98%
Cayman
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5 mg

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75 €

Cay11338-1
CAS: 99533-​80-​9
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
Cayman
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1 mg

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447 €

Cay11338-100
CAS: 99533-​80-​9
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
Cayman
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100 µg

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73 €

Cay11338-50
CAS: 99533-​80-​9
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
Cayman
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50 µg

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41 €

Cay11338-500
CAS: 99533-​80-​9
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
K252a is a staurosporine analog isolated from Nocardiopsis sp. soil fungi that inhibits protein kinase C (PKC), PKA, CaM kinase II, and phosphorylase kinase with IC50 values of 470, 140, 270, and 1.7 nM, respectively. Because it inhibits neurotrophin rece ... mehr
MW: 467 D
Formula: C27H21N3O5
Purity: >98%
Cayman
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500 µg

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284 €

Cay11593-1
CAS: 1032350-​13-​2
Allosteric Akt inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB?, ?, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK 2206 is an orally active, allosteric Akt inhibitor that is equally potent ... mehr
MW: 480 D
Formula: C25H21N5O . 2HCl
Cayman
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1 mg

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41 €

Cay11593-10
CAS: 1032350-​13-​2
Allosteric Akt inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB?, ?, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK 2206 is an orally active, allosteric Akt inhibitor that is equally potent ... mehr
MW: 480 D
Formula: C25H21N5O . 2HCl
Cayman
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10 mg

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183 €

Cay11593-25
CAS: 1032350-​13-​2
Allosteric Akt inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB?, ?, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK 2206 is an orally active, allosteric Akt inhibitor that is equally potent ... mehr
MW: 480 D
Formula: C25H21N5O . 2HCl
Cayman
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25 mg

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406 €

Cay11593-5
CAS: 1032350-​13-​2
Allosteric Akt inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (1, 2, 3, also known as protein kinase B isoforms PKB?, ?, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. MK 2206 is an orally active, allosteric Akt inhibitor that is equally potent ... mehr
MW: 480 D
Formula: C25H21N5O . 2HCl
Cayman
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5 mg

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114 €

Cay11597-10
CAS: 159351-​69-​6
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that, as part of two distinct complexes (mTORC1 and mTORC2), plays pivotal roles in intracellular signaling. Everolimus is a hydroxyethyl ether rapamycin (Item No. 13346) derivative tha ... mehr
MW: 958 D
Formula: C53H83NO14
Cayman
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10 mg

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114 €

Cay11597-25
CAS: 159351-​69-​6
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that, as part of two distinct complexes (mTORC1 and mTORC2), plays pivotal roles in intracellular signaling. Everolimus is a hydroxyethyl ether rapamycin (Item No. 13346) derivative tha ... mehr
MW: 958 D
Formula: C53H83NO14
Cayman
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25 mg

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226 €

Cay11597-5
CAS: 159351-​69-​6
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine/threonine kinase that, as part of two distinct complexes (mTORC1 and mTORC2), plays pivotal roles in intracellular signaling. Everolimus is a hydroxyethyl ether rapamycin (Item No. 13346) derivative tha ... mehr
MW: 958 D
Formula: C53H83NO14
Cayman
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5 mg

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75 €

Cay11601-10
CAS: 170364-​57-​5
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCa, PKCgamma, and PKCe (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, ... mehr
MW: 515 D
Formula: C32H29N5O2
Purity: >98%
Cayman
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10 mg

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115 €

Cay11601-25
CAS: 170364-​57-​5
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCa, PKCgamma, and PKCe (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, ... mehr
MW: 515 D
Formula: C32H29N5O2
Purity: >98%
Cayman
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25 mg

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242 €

Cay11601-5
CAS: 170364-​57-​5
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCa, PKCgamma, and PKCe (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, ... mehr
MW: 515 D
Formula: C32H29N5O2
Purity: >98%
Cayman
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5 mg

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80 €

Cay11601-50
CAS: 170364-​57-​5
PKCbeta inhibitor Erklärungen der Abkürzungen ansehen.
Enzastaurin is a potent inhibitor of PKCbeta (IC50 = 6 nM), with modest selectivity over PKCa, PKCgamma, and PKCe (IC50 = 39, 83, and 110 nM, respectively). At 3 µM, enzastaurin also inhibits signaling through the Akt pathway. It suppresses angiogenesis, ... mehr
MW: 515 D
Formula: C32H29N5O2
Purity: >98%
Cayman
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50 mg

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404 €

Cay11658-10
CAS: 4311-​88-​0
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 259 D
Formula: C13H13N3OS
Purity: >98%
Cayman
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10 mg

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58 €

Cay11658-100
CAS: 4311-​88-​0
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 259 D
Formula: C13H13N3OS
Purity: >98%
Cayman
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100 mg

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325 €

Cay11658-5
CAS: 4311-​88-​0
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 259 D
Formula: C13H13N3OS
Purity: >98%
Cayman
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5 mg

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32 €

Cay11658-50
CAS: 4311-​88-​0
RIP1 kinase inhibitor Erklärungen der Abkürzungen ansehen.
Necroptosis is a regulated caspase-​independent cell death mechanism that results in morphological features resembling necrosis. Serine/threonine kinase activity of the death domain receptor-​associated molecule RIP1 is thought to be essential for Fas ligan ... mehr
MW: 259 D
Formula: C13H13N3OS
Purity: >98%
Cayman
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50 mg

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195 €

Cay11704-1
CAS: 77307-​50-​7
RSK2 inhibitor Erklärungen der Abkürzungen ansehen.
The p90 ribosomal S6 kinases (RSK) 1-​4 are downstream members of the extracellular signal-​regulated kinase (ERK)/MAPK cascade. SL 0101-​1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr
MW: 516 D
Formula: C25H24O12
Purity: >98%
Cayman
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1 mg

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161 €

Cay11704-5
CAS: 77307-​50-​7
RSK2 inhibitor Erklärungen der Abkürzungen ansehen.
The p90 ribosomal S6 kinases (RSK) 1-​4 are downstream members of the extracellular signal-​regulated kinase (ERK)/MAPK cascade. SL 0101-​1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr
MW: 516 D
Formula: C25H24O12
Purity: >98%
Cayman
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5 mg

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677 €

Cay11704-500
CAS: 77307-​50-​7
RSK2 inhibitor Erklärungen der Abkürzungen ansehen.
The p90 ribosomal S6 kinases (RSK) 1-​4 are downstream members of the extracellular signal-​regulated kinase (ERK)/MAPK cascade. SL 0101-​1 is a kaempferol glycoside, isolated from the tropical plant F. refracta, that selectively inhibits RSK2 with an IC50 v ... mehr
MW: 516 D
Formula: C25H24O12
Purity: >98%
Cayman
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500 µg

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85 €

Cay11793-1
CAS: 694433-​59-​5
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
SB 505124 inhibits the TGF-​beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-​dependently inhibits ALK4-​, ALK5-​, and ALK7 ... mehr
MW: 335 D
Formula: C20H21N3O2
Purity: >98%
Cayman
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1 mg

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21 €

Cay11793-10
CAS: 694433-​59-​5
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
SB 505124 inhibits the TGF-​beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-​dependently inhibits ALK4-​, ALK5-​, and ALK7 ... mehr
MW: 335 D
Formula: C20H21N3O2
Purity: >98%
Cayman
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10 mg

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167 €

Cay11793-25
CAS: 694433-​59-​5
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
SB 505124 inhibits the TGF-​beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-​dependently inhibits ALK4-​, ALK5-​, and ALK7 ... mehr
MW: 335 D
Formula: C20H21N3O2
Purity: >98%
Cayman
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25 mg

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340 €

Cay11793-5
CAS: 694433-​59-​5
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
SB 505124 inhibits the TGF-​beta1 receptor serine/threonine kinase ALK5 with an IC50 value of 47 nM. Though it is a less potent antagonist of ALK4 (IC50 = 129 nM) and ALK7, SB 505124 selectively and concentration-​dependently inhibits ALK4-​, ALK5-​, and ALK7 ... mehr
MW: 335 D
Formula: C20H21N3O2
Purity: >98%
Cayman
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5 mg

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94 €

Cay11801-1
CAS: 110448-​33-​4
MLCK inhibitor Erklärungen der Abkürzungen ansehen.
ML-​7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-​competitive inhibition of Ca2+calmodulin-​dependent and -​independent smooth muscle MLCKs. It exhibits a 10-​fold more potent inhibition of ML ... mehr
MW: 452 D
Formula: C15H17IN2O2S - HCl
Purity: >95%
Cayman
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1 mg

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29 €

Cay11801-10
CAS: 110448-​33-​4
MLCK inhibitor Erklärungen der Abkürzungen ansehen.
ML-​7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-​competitive inhibition of Ca2+calmodulin-​dependent and -​independent smooth muscle MLCKs. It exhibits a 10-​fold more potent inhibition of ML ... mehr
MW: 452 D
Formula: C15H17IN2O2S - HCl
Purity: >95%
Cayman
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10 mg

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122 €

Cay11801-5
CAS: 110448-​33-​4
MLCK inhibitor Erklärungen der Abkürzungen ansehen.
ML-​7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-​competitive inhibition of Ca2+calmodulin-​dependent and -​independent smooth muscle MLCKs. It exhibits a 10-​fold more potent inhibition of ML ... mehr
MW: 452 D
Formula: C15H17IN2O2S - HCl
Purity: >95%
Cayman
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5 mg

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82 €

Cay11801-50
CAS: 110448-​33-​4
MLCK inhibitor Erklärungen der Abkürzungen ansehen.
ML-​7 inhibits smooth muscle myosin light chain kinase (MLCK) with a Ki value of 0.3 µM and displays reversible, ATP-​competitive inhibition of Ca2+calmodulin-​dependent and -​independent smooth muscle MLCKs. It exhibits a 10-​fold more potent inhibition of ML ... mehr
MW: 452 D
Formula: C15H17IN2O2S - HCl
Purity: >95%
Cayman
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50 mg

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342 €

Cay11802-1
CAS: 1062368-​24-​4
BMP type I receptor inhibitor Erklärungen der Abkürzungen ansehen.
Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-​beta superfamily. LDN193189 inhibits SMAD1/5/8 phosphorylation by the ... mehr
MW: 406 D
Formula: C25H22N6
Purity: >95%
Cayman
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1 mg

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41 €

Cay11802-10
CAS: 1062368-​24-​4
BMP type I receptor inhibitor Erklärungen der Abkürzungen ansehen.
Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-​beta superfamily. LDN193189 inhibits SMAD1/5/8 phosphorylation by the ... mehr
MW: 406 D
Formula: C25H22N6
Purity: >95%
Cayman
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10 mg

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244 €

Cay11802-5
CAS: 1062368-​24-​4
BMP type I receptor inhibitor Erklärungen der Abkürzungen ansehen.
Normal development and tissue repair are controlled in part by SMADs, a family of intracellular proteins that are activated by signaling via serine/threonine kinase receptors of the TGF-​beta superfamily. LDN193189 inhibits SMAD1/5/8 phosphorylation by the ... mehr
MW: 406 D
Formula: C25H22N6
Purity: >95%
Cayman
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5 mg

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162 €

Cay11811-1
CAS: 1224844-​38-​5
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr
MW: 309
Formula: C15H15N7O
Purity: >98%
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1 mg

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34 €

Cay11811-10
CAS: 1224844-​38-​5
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr
MW: 309
Formula: C15H15N7O
Purity: >98%
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10 mg

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269 €

Cay11811-5
CAS: 1224844-​38-​5
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. INK128 is an inhibitor of TOR ... mehr
MW: 309
Formula: C15H15N7O
Purity: >98%
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5 mg

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152 €

Cay11967-10
CAS: 866405-​64-​3
AMPK inhibitor, autophagy inducer Erklärungen der Abkürzungen ansehen.
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCtheta, PKA, and JAK3. Dorsomorphin can also dose-​dependently inhibit the bone morphoge ... mehr
MW: 399 D
Formula: C24H25N5O
Purity: >98%
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10 mg

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144 €

Cay11967-5
CAS: 866405-​64-​3
AMPK inhibitor, autophagy inducer Erklärungen der Abkürzungen ansehen.
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCtheta, PKA, and JAK3. Dorsomorphin can also dose-​dependently inhibit the bone morphoge ... mehr
MW: 399 D
Formula: C24H25N5O
Purity: >98%
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5 mg

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75 €

Cay11967-50
CAS: 866405-​64-​3
AMPK inhibitor, autophagy inducer Erklärungen der Abkürzungen ansehen.
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCtheta, PKA, and JAK3. Dorsomorphin can also dose-​dependently inhibit the bone morphoge ... mehr
MW: 399 D
Formula: C24H25N5O
Purity: >98%
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50 mg

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452 €

Cay12006-10
CAS: 82-​08-​6
Broad specifity kinase inhibitor Erklärungen der Abkürzungen ansehen.
Rottlerin was originally identified as an inhibitor of PKCd (IC50 = 3 µM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-​K2 (IC50s = 1.9 and 5 µM, respectively). It can act as a direct mitochondrial unc ... mehr
MW: 516 D
Formula: C30H28O8
Purity: >90%
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10 mg

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57 €

Cay12006-50
CAS: 82-​08-​6
Broad specifity kinase inhibitor Erklärungen der Abkürzungen ansehen.
Rottlerin was originally identified as an inhibitor of PKCd (IC50 = 3 µM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-​K2 (IC50s = 1.9 and 5 µM, respectively). It can act as a direct mitochondrial unc ... mehr
MW: 516 D
Formula: C30H28O8
Purity: >90%
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50 mg

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256 €

Cay13031-10
CAS: 301836-​41-​9
ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor Erklärungen der Abkürzungen ansehen.
SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.
MW: 384 D
Formula: C22H16N4O3
Purity: >98%
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10 mg

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125 €

Cay13031-25
CAS: 301836-​41-​9
ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor Erklärungen der Abkürzungen ansehen.
SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.
MW: 384 D
Formula: C22H16N4O3
Purity: >98%
Cayman
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25 mg

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261 €

Cay13031-5
CAS: 301836-​41-​9
ALK4 inhibitor, ALK5 inhibitor, ALK7 inhibitor Erklärungen der Abkürzungen ansehen.
SB 431542 is a potent and selective inhibitor of the TGF-beta1 receptor ALK5. SB 431542 specifically blocks Smad signaling. It suppresses renewal in embryonic and induced pluripotent stem cells and promotes their differentiation.
MW: 384 D
Formula: C22H16N4O3
Purity: >98%
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5 mg

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94 €

Cay13067-10
CAS: 152121-​47-​6
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK.
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
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10 mg

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172 €

Cay13067-100
CAS: 152121-​47-​6
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK.
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
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100 mg

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1267 €

Cay13067-5
CAS: 152121-​47-​6
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK.
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
Cayman
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5 mg

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90 €

Cay13067-50
CAS: 152121-​47-​6
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
SB 203580 is a pyridinyl imidazole inhibitor of p38 MAPK that specifically blocks its kinase activity. SB 203580 does not however, disrupt JNK activity, which is activated by similar stressors to those which activate p38 MAPK.
MW: 377 D
Formula: C21H16FN3OS
Purity: >98%
Cayman
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50 mg

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724 €

Cay13108-10
CAS: 745833-​23-​2
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
VX-​702 is a third generation inhibitor of p38 mitogen-​activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-​competitive fashion. It inhibits IL-​6, IL-​1beta, and TNFalpha production in LPS-​primed ... mehr
MW: 404 D
Formula: C19H12F4N4O2
Purity: >95%
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10 mg

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42 €

Cay13108-25
CAS: 745833-​23-​2
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
VX-​702 is a third generation inhibitor of p38 mitogen-​activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-​competitive fashion. It inhibits IL-​6, IL-​1beta, and TNFalpha production in LPS-​primed ... mehr
MW: 404 D
Formula: C19H12F4N4O2
Purity: >98%
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25 mg

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100 €

Cay13108-5
CAS: 745833-​23-​2
p38 MAP kinase inhibitor Erklärungen der Abkürzungen ansehen.
VX-​702 is a third generation inhibitor of p38 mitogen-​activated protein (MAP) kinases, binding to both p38alpha and p38beta (Kd = 3.7 and 17 nM, respectively) in an ATP-​competitive fashion. It inhibits IL-​6, IL-​1beta, and TNFalpha production in LPS-​primed ... mehr
MW: 404 D
Formula: C19H12F4N4O2
Purity: >95%
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5 mg

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22 €

Cay13109-100
CAS: 518-​82-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Emodin is a naturally-​occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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100 mg

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104 €

Cay13109-25
CAS: 518-​82-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Emodin is a naturally-​occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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25 mg

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29 €

Cay13109-50
CAS: 518-​82-​1
CK2 inhibitor Erklärungen der Abkürzungen ansehen.
Emodin is a naturally-​occurring anthraquinone found in a variety of plants used in traditional Chinese medicine. Purified emodin has diverse effects, including the suppression of inflammation, dyslipidemia, and cancer. At a molecular level, emodin directl ... mehr
MW: 270 D
Formula: C15H10O5
Purity: >98%
Cayman
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50 mg

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56 €

Cay13122-1
CAS: 252917-​06-​9
GSK3alpha and GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr
MW: 465
Formula: C22H18Cl2N8
Purity: >98%
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1 mg

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49 €

Cay13122-10
CAS: 252917-​06-​9
GSK3alpha and GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr
MW: 465
Formula: C22H18Cl2N8
Purity: >98%
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10 mg

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390 €

Cay13122-5
CAS: 252917-​06-​9
GSK3alpha and GSK3beta inhibitor Erklärungen der Abkürzungen ansehen.
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that has been shown to play a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 valu ... mehr
MW: 465
Formula: C22H18Cl2N8
Purity: >98%
Cayman
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5 mg

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219 €

Cay13123-10
CAS: 667463-​62-​9
GSK-​3 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells.
MW: 356 D
Formula: C16H10BrN3O2
Purity: >98%
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10 mg

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223 €

Cay13123-25
CAS: 667463-​62-​9
GSK-​3 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells.
MW: 356 D
Formula: C16H10BrN3O2
Purity: >98%
Cayman
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25 mg

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487 €

Cay13123-5
CAS: 667463-​62-​9
GSK-​3 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeable selective, reversible inhibitor of GSK-3alpha/beta. Inhibition of GSK by BIO has been shown to result in the activation of the Wnt signaling pathway and sustained pluripotency in human and murine embryonic stem cells.
MW: 356 D
Formula: C16H10BrN3O2
Purity: >98%
Cayman
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5 mg

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125 €

Cay13297-10
CAS: 118409-​62-​4
ERK inhibitor Erklärungen der Abkürzungen ansehen.
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo.
MW: 215 D
Formula: C10H5N3O3
Purity: >95%
Cayman
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10 mg

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223 €

Cay13297-25
CAS: 118409-​62-​4
ERK inhibitor Erklärungen der Abkürzungen ansehen.
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo.
MW: 215 D
Formula: C10H5N3O3
Purity: >95%
Cayman
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25 mg

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487 €

Cay13297-5
CAS: 118409-​62-​4
ERK inhibitor Erklärungen der Abkürzungen ansehen.
The tyrphostin AG-126 selectively inhibits the phosphorylation of ERK1 (p44) and ERK2 (p42). It blocks the production of TNF-alpha in vitro and in vivo.
MW: 215 D
Formula: C10H5N3O3
Purity: >95%
Cayman
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5 mg

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125 €

Cay13298-10
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC.
MW: 412 D
Formula: C25H24N4O2
Purity: >95%
Cayman
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10 mg

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152 €

Cay13298-25
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC.
MW: 412 D
Formula: C25H24N4O2
Purity: >95%
Cayman
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25 mg

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361 €

Cay13298-5
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC.
MW: 412 D
Formula: C25H24N4O2
Purity: >95%
Cayman
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5 mg

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80 €

Cay13298-50
CAS: 133052-​90-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Bisindolylmaleimide I (BIM) is a highly selective, cell-permeable, and reversible protein kinase C (PKC) inhibitor. It acts as a competitive inhibitor for the ATP binding site of PKC.
MW: 412 D
Formula: C25H24N4O2
Purity: >95%
Cayman
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50 mg

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640 €

Cay13299-10
CAS: 119139-​23-​0
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM).
MW: 327 D
Formula: C20H13N3O2
Purity: >98%
Cayman
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10 mg

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380 €

Cay13299-25
CAS: 119139-​23-​0
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM).
MW: 327 D
Formula: C20H13N3O2
Purity: >98%
Cayman
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25 mg

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833 €

Cay13299-5
CAS: 119139-​23-​0
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Cell permeable inhibitor of protein kinase C (PKC) (IC50 values 0.10 to 0.55 µM). It was designed to be more discriminative than staurosporine (Catalog No. Cay81590). However, it also inhibits protein kinase A (IC50 values 2 to 11.8 µM).
MW: 327 D
Formula: C20H13N3O2
Purity: >98%
Cayman
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5 mg

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215 €

Cay13300-1
CAS: 113963-​68-​1
S6K inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.
MW: 341 D
Formula: C21H15N3O2
Purity: >98%
Cayman
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1 mg

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59 €

Cay13300-10
CAS: 113963-​68-​1
S6K inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.
MW: 341 D
Formula: C21H15N3O2
Purity: >98%
Cayman
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10 mg

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473 €

Cay13300-25
CAS: 113963-​68-​1
S6K inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-6045 blocks the activation of mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.
MW: 341 D
Formula: C21H15N3O2
Purity: >98%
Cayman
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25 mg

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1036 €

Cay13300-5
CAS: 113963-​68-​1
S6K inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-​6045 is a weak inhibitor of protein kinase C (PKC). While effectively inactive as a PKC inhibitor, Ro 31-​6045 blocks the activation of mitogen-​stimulated protein kinase p70s6k/p85s6k (S6K) in vivo.(±)-​7-​epi Jasmonic acid is a plant growth regulator ... mehr
MW: 341 D
Formula: C21H15N3O2
Purity: >98%
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5 mg

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267 €

Cay13305-10
CAS: 301836-​43-​1
CK1 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53.
MW: 398 D
Formula: C23H18N4O3
Purity: >98%
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10 mg

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176 €

Cay13305-5
CAS: 301836-​43-​1
CK1 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53.
MW: 398 D
Formula: C23H18N4O3
Purity: >98%
Cayman
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5 mg

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100 €

Cay13305-50
CAS: 301836-​43-​1
CK1 inhibitor Erklärungen der Abkürzungen ansehen.
Cell-permeant inhibitor of casein kinase 1, it is a less effective inhibitor of PKD1 and p38alpha MAPK, and only weakly affects the activities of a panel of kinases tested. Blocks CK1-mediated phosphorylation of FOXO1a, RhoB, and p53.
MW: 398 D
Formula: C23H18N4O3
Purity: >98%
Cayman
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50 mg

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771 €

Cay13308-10
CAS: 154447-​35-​5
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation.
MW: 281 D
Formula: C17H15NO3
Purity: >95%
Cayman
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10 mg

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144 €

Cay13308-25
CAS: 154447-​35-​5
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation.
MW: 281 D
Formula: C17H15NO3
Purity: >95%
Cayman
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25 mg

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340 €

Cay13308-5
CAS: 154447-​35-​5
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation.
MW: 281 D
Formula: C17H15NO3
Purity: >95%
Cayman
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5 mg

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75 €

Cay13308-50
CAS: 154447-​35-​5
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK. It impairs cellular DNA double strand break repair and decreases survival in cells exposed to ionizing radiation.
MW: 281 D
Formula: C17H15NO3
Purity: >95%
Cayman
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50 mg

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603 €

Cay13311-10
CAS: 133053-​19-​7
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Gö 6983 inhibits several isoforms of protein kinase C. It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.
MW: 442 D
Formula: C26H26N4O3
Purity: >98%
Cayman
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10 mg

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209 €

Cay13311-5
CAS: 133053-​19-​7
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Gö 6983 inhibits several isoforms of protein kinase C. It provides cardioprotective effects in myocardial ischemia/reperfusion by attenuating contractile dysfunction.
MW: 442 D
Formula: C26H26N4O3
Purity: >98%
Cayman
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5 mg

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139 €

Cay13312-25
CAS: 116700-​36-​8
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA.
MW: 324 D
Formula: C11H13N3O2S ? 2HCl
Purity: >98%
Cayman
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25 mg

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110 €

Cay13312-50
CAS: 116700-​36-​8
Kinase inhibitor Erklärungen der Abkürzungen ansehen.
H-9 (hydrochloride), an isoquinolinesulfonamide protein kinase inhibitor, is a competitive inhibitor of PKC, PKG, and PKA.
MW: 324 D
Formula: C11H13N3O2S ? 2HCl
Purity: >98%
Cayman
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50 mg

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195 €

Cay13314-10
CAS: 160807-​49-​8
GSK-​3beta inhibitor, CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types.
MW: 277 D
Formula: C16H11N3O2
Purity: >98%
Cayman
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10 mg

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135 €

Cay13314-25
CAS: 160807-​49-​8
GSK-​3beta inhibitor, CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types.
MW: 277 D
Formula: C16H11N3O2
Purity: >98%
Cayman
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25 mg

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319 €

Cay13314-5
CAS: 160807-​49-​8
GSK-​3beta inhibitor, CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types.
MW: 277 D
Formula: C16H11N3O2
Purity: >98%
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5 mg

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71 €

Cay13314-50
CAS: 160807-​49-​8
GSK-​3beta inhibitor, CDK inhibitor Erklärungen der Abkürzungen ansehen.
Potent inhibitor of glycogen synthase kinase-3beta. It prevents tau protein phosphorylation both in vitro and in vivo. It also inhibits cyclin-dependent kinases (CDK) and reversibly inhibits the proliferation of many cells types.
MW: 277 D
Formula: C16H11N3O2
Purity: >98%
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50 mg

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566 €

Cay13318-10
CAS: 127191-​97-​3
CAMKII inhibitor Erklärungen der Abkürzungen ansehen.
Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7.
MW: 721 D
Formula: C38H35N5O6S2
Purity: >98%
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10 mg

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390 €

Cay13318-25
CAS: 127191-​97-​3
CAMKII inhibitor Erklärungen der Abkürzungen ansehen.
Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7.
MW: 721 D
Formula: C38H35N5O6S2
Purity: >98%
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25 mg

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853 €

Cay13318-5
CAS: 127191-​97-​3
CAMKII inhibitor Erklärungen der Abkürzungen ansehen.
Selective, cell permeable inhibitor of calcium/calmodulin-dependent kinase II.1 It does not affect the activity of several other kinases when tested at 10 µM. KN-62 also acts as a non-competitive antagonist of the purinergic receptor P2RX7.
MW: 721 D
Formula: C38H35N5O6S2
Purity: >98%
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5 mg

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219 €

Cay13319-1
CAS: 139298-​40-​1
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-93 is a water-soluble, selective inhibitor of Ca2 dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells.
MW: 501 D
Formula: C26H29ClN2O4S
Purity: >98%
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1 mg

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100 €

Cay13319-10
CAS: 139298-​40-​1
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-93 is a water-soluble, selective inhibitor of Ca2-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells.
MW: 501 D
Formula: C26H29ClN2O4S
Purity: >98%
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10 mg

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798 €

Cay13319-5
CAS: 139298-​40-​1
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-93 is a water-soluble, selective inhibitor of Ca2-dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase. It inhibits histamine-induced aminopyrine uptake in parietal cells.
MW: 501 D
Formula: C26H29ClN2O4S
Purity: >98%
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5 mg

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449 €

Cay13322-10
CAS: 522629-​08-​9
MAPK-​interacting kinase 1 inhibitor Erklärungen der Abkürzungen ansehen.
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells.
MW: 244 D
Formula: C11H9FN6
Purity: >95%
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10 mg

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288 €

Cay13322-25
CAS: 522629-​08-​9
MAPK-​interacting kinase 1 inhibitor Erklärungen der Abkürzungen ansehen.
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells.
MW: 244 D
Formula: C11H9FN6
Purity: >95%
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25 mg

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630 €

Cay13322-5
CAS: 522629-​08-​9
MAPK-​interacting kinase 1 inhibitor Erklärungen der Abkürzungen ansehen.
CGP 57380 is a selective inhibitor of MAP kinase-interacting kinase 1 (MNK1). It blocks the phosphorylation of eIF4E and also dose-dependently inhibits TNF-alpha production in RAW 264.7 cells.
MW: 244 D
Formula: C11H9FN6
Purity: >95%
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5 mg

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162 €

Cay13332-1
CAS: 913844-​45-​8
ROCK inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 449 D
Formula: C18H24N4O3S . 2HCl
Purity: >98%
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1 mg

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166 €

Cay13332-5
CAS: 913844-​45-​8
ROCK inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 449 D
Formula: C18H24N4O3S . 2HCl
Purity: >98%
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5 mg

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696 €

Cay13332-500
CAS: 913844-​45-​8
ROCK inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 449 D
Formula: C18H24N4O3S . 2HCl
Purity: >98%
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500 µg

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87 €

Cay13333-10
CAS: 138516-​31-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-7549 is a selective protein kinase C inhibitor that acts at the ATP binding site of PKC (preference for PKCalpha). At 10 µM Ro 31-7549 does not inhibit the tyrosine phosphorylation or the activation of phospholipase C gamma1.
MW: 458 D
Formula: C24H22N4O2 ? C2H4O2
Purity: >98%
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10 mg

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325 €

Cay13333-5
CAS: 138516-​31-​1
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-7549 is a selective protein kinase C inhibitor that acts at the ATP binding site of PKC (preference for PKCalpha). At 10 µM Ro 31-7549 does not inhibit the tyrosine phosphorylation or the activation of phospholipase C gamma1.
MW: 458 D
Formula: C24H22N4O2 ? C2H4O2
Purity: >98%
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5 mg

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173 €

Cay13334-1
CAS: 138489-​18-​6
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-​8220 is a potent, cell-​permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-​alpha, PKC-​betaI, PKC-​betaII, PKC-​gamma, and PKC-​epsilon, respectively). It is a poor inhibitor of protein ki ... mehr
MW: 553 D
Formula: C25H23N5O2S . CH4SO3
Purity: 98%
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1 mg

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41 €

Cay13334-10
CAS: 138489-​18-​6
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-​8220 is a potent, cell-​permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-​alpha, PKC-​betaI, PKC-​betaII, PKC-​gamma, and PKC-​epsilon, respectively). It is a poor inhibitor of protein ki ... mehr
MW: 553 D
Formula: C25H23N5O2S . CH4SO3
Purity: 98%
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10 mg

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231 €

Cay13334-5
CAS: 138489-​18-​6
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Ro 31-​8220 is a potent, cell-​permeable bisindolylmaleimide inhibitor of protein kinase C (PKC) isoforms (IC50 = 5, 24, 14, 27, and 24 nM for PKC-​alpha, PKC-​betaI, PKC-​betaII, PKC-​gamma, and PKC-​epsilon, respectively). It is a poor inhibitor of protein ki ... mehr
MW: 553 D
Formula: C25H23N5O2S . CH4SO3
Purity: 98%
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5 mg

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157 €

Cay13341-10
CAS: 396129-​53-​6
TGFbetaRI inhibitor Erklärungen der Abkürzungen ansehen.
Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells.
MW: 272 D
Formula: C17H12N4
Purity: >98%
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10 mg

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164 €

Cay13341-25
CAS: 396129-​53-​6
TGFbetaRI inhibitor Erklärungen der Abkürzungen ansehen.
Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells.
MW: 272 D
Formula: C17H12N4
Purity: >98%
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25 mg

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386 €

Cay13341-5
CAS: 396129-​53-​6
TGFbetaRI inhibitor Erklärungen der Abkürzungen ansehen.
Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells.
MW: 272 D
Formula: C17H12N4
Purity: >98%
Cayman
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5 mg

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86 €

Cay13341-50
CAS: 396129-​53-​6
TGFbetaRI inhibitor Erklärungen der Abkürzungen ansehen.
Selective inhibitor of TGF-beta RI. It inhibits TGF-beta-induced cell growth in NIH 3T3 mouse fibroblasts1 and TGF-beta-directed Smad phosphorylation, synthesis of fibronectin, PAI-1 and uPA protein, and matrigel invasion in MDA-MB-231 cells.
MW: 272 D
Formula: C17H12N4
Purity: >98%
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50 mg

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687 €

Cay13344-10
CAS: 869185-​85-​3
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1.
MW: 413 D
Formula: C21H16FN3OS ? HCl
Purity: >98%
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10 mg

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198 €

Cay13344-25
CAS: 869185-​85-​3
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1.
MW: 413 D
Formula: C21H16FN3OS ? HCl
Purity: >98%
Cayman
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25 mg

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470 €

Cay13344-5
CAS: 869185-​85-​3
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1.
MW: 413 D
Formula: C21H16FN3OS ? HCl
Purity: >98%
Cayman
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5 mg

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104 €

Cay13344-50
CAS: 869185-​85-​3
p38 MAPK inhibitor Erklärungen der Abkürzungen ansehen.
p38 MAPK activity in heat-shocked HeLa cells and osmotically stressed PC12 cells is inhibited by SB 203580. It also prevents the activation of PKB/Akt by inhibiting phosphoinositide-dependent protein kinase 1.
MW: 413 D
Formula: C21H16FN3OS ? HCl
Purity: >98%
Cayman
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50 mg

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835 €

Cay13597-10
CAS: 938440-​64-​3
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-​0063794 i ... mehr
MW: 465 D
Formula: C25H31N5O4
Purity: >98%
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10 mg

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157 €

Cay13597-100
CAS: 938440-​64-​3
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-​0063794 i ... mehr
MW: 465 D
Formula: C25H31N5O4
Purity: >98%
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100 mg

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609 €

Cay13597-5
CAS: 938440-​64-​3
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-​0063794 i ... mehr
MW: 465 D
Formula: C25H31N5O4
Purity: >98%
Cayman
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5 mg

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87 €

Cay13597-50
CAS: 938440-​64-​3
TORC1 / 2 inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-​0063794 i ... mehr
MW: 465 D
Formula: C25H31N5O4
Purity: >98%
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50 mg

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435 €

Cay13601-10
CAS: 331771-​20-​1
Aurora B kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr
MW: 514 D
Formula: C29H31N5O4
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10 mg

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100 €

Cay13601-5
CAS: 331771-​20-​1
Aurora B kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr
MW: 514 D
Formula: C29H31N5O4
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5 mg

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56 €

Cay13601-50
CAS: 331771-​20-​1
Aurora B kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B ... mehr
MW: 514 D
Formula: C29H31N5O4
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50 mg

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334 €

Cay13604-10
CAS: 1062169-​56-​5
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
WYE-​354 is a potent cell-​permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-​kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr
MW: 495 D
Formula: C24H29N7O5
Purity: >98%
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10 mg

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166 €

Cay13604-25
CAS: 1062169-​56-​5
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
WYE-​354 is a potent cell-​permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-​kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr
MW: 495 D
Formula: C24H29N7O5
Purity: >98%
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25 mg

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392 €

Cay13604-5
CAS: 1062169-​56-​5
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
WYE-​354 is a potent cell-​permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-​kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr
MW: 495 D
Formula: C24H29N7O5
Purity: >98%
Cayman
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5 mg

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87 €

Cay13604-50
CAS: 1062169-​56-​5
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
WYE-​354 is a potent cell-​permeable inhibitor of mTOR (IC50 = 4.3 nM) which blocks signaling through both mTOR complex 1 (mTORC1) and mTORC2. It is a much weaker inhibitor of phosphatidylinositol 3-​kinase akpha (PI3Kalpha, IC50 = 1026 nM) and other kinases ... mehr
MW: 495 D
Formula: C24H29N7O5
Purity: >98%
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50 mg

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696 €

Cay13641-1
IGF-​1R kinase inhibitor Erklärungen der Abkürzungen ansehen.
Insulin-​like growth factor 1 receptor (IGF-​1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-​1R signaling has been implicated in the development and progre ... mehr
MW: 512 D
Formula: C27H29N5O . 2HCl
Purity: >98%
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1 mg

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110 €

Cay13641-10
IGF-​1R kinase inhibitor Erklärungen der Abkürzungen ansehen.
Insulin-​like growth factor 1 receptor (IGF-​1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-​1R signaling has been implicated in the development and progre ... mehr
MW: 512 D
Formula: C27H29N5O . 2HCl
Purity: >98%
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10 mg

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731 €

Cay13641-5
IGF-​1R kinase inhibitor Erklärungen der Abkürzungen ansehen.
Insulin-​like growth factor 1 receptor (IGF-​1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-​1R signaling has been implicated in the development and progre ... mehr
MW: 512 D
Formula: C27H29N5O . 2HCl
Purity: >98%
Cayman
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5 mg

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418 €

Cay13641-500
IGF-​1R kinase inhibitor Erklärungen der Abkürzungen ansehen.
Insulin-​like growth factor 1 receptor (IGF-​1R) is a receptor tyrosine kinase whose activation leads to angiogenesis as well as cell proliferation, survival, transformation, and metastasis. IGF-​1R signaling has been implicated in the development and progre ... mehr
MW: 512 D
Formula: C27H29N5O . 2HCl
Purity: >98%
Cayman
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500 µg

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75 €

Cay13643-1
CAS: 1092351-​67-​1
mTOR kinase inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr
MW: 308 D
Formula: C16H16N6O
Purity: >95%
Cayman
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1 mg

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20 €

Cay13643-10
CAS: 1092351-​67-​1
mTOR kinase inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr
MW: 308 D
Formula: C16H16N6O
Purity: >95%
Cayman
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10 mg

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137 €

Cay13643-5
CAS: 1092351-​67-​1
mTOR kinase inhibitor Erklärungen der Abkürzungen ansehen.
The mammalian target of rapamycin (mTOR) is a serine-​threonine kinase that is central to two protein complexes, mTORC1 and mTORC2. These complexes are differentially regulated (e.g., only mTORC1 is sensitive to rapamycin) and regulate different pathways. ... mehr
MW: 308 D
Formula: C16H16N6O
Purity: >95%
Cayman
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5 mg

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79 €

Cay13687-1
CAS: 1038549-​25-​5
Rock kinase inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 443 D
Formula: C25H25N5O3
Purity: >98%
Cayman
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1 mg

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53 €

Cay13687-10
CAS: 1038549-​25-​5
Rock kinase inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 443 D
Formula: C25H25N5O3
Purity: >98%
Cayman
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10 mg

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427 €

Cay13687-25
CAS: 1038549-​25-​5
Rock kinase inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 443 D
Formula: C25H25N5O3
Purity: >98%
Cayman
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25 mg

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934 €

Cay13687-5
CAS: 1038549-​25-​5
Rock kinase inhibitor Erklärungen der Abkürzungen ansehen.
Two Rho kinases (ROCK), ROCK-​I and ROCK-​II, act downstream of the G protein Rho to regulate cytoskeletal stability. The Rho kinases play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, an ... mehr
MW: 443 D
Formula: C25H25N5O3
Purity: >98%
Cayman
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5 mg

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240 €

Cay13864-1
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-​93 is a selective inhibitor of Ca2+/calmodulin-​dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-​phosphodiesterase. It inhibits histamine-​induced a ... mehr
MW: 537 D
Formula: C26H29ClN2O4S - HCl
Purity: >98%
Cayman
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1 mg

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100 €

Cay13864-10
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-​93 is a selective inhibitor of Ca2+/calmodulin-​dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-​phosphodiesterase. It inhibits histamine-​induced a ... mehr
MW: 537 D
Formula: C26H29ClN2O4S - HCl
Purity: >98%
Cayman
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10 mg

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798 €

Cay13864-5
CaMKII inhibitor Erklärungen der Abkürzungen ansehen.
KN-​93 is a selective inhibitor of Ca2+/calmodulin-​dependent kinase II (CaMKII), competitively blocking CaM binding to the kinase (Ki = 370 nM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-​phosphodiesterase. It inhibits histamine-​induced a ... mehr
MW: 537 D
Formula: C26H29ClN2O4S - HCl
Purity: >98%
Cayman
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5 mg

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449 €

Cay13964-1
CAS: 169939-​93-​9
PKCbeta1 / PKCbeta2 Inhibitor Erklärungen der Abkürzungen ansehen.
LY333531 is a selective and potent inhibitor of PKCbeta1 and PKCbeta2 (IC50 = 4.7 and 5.9 nM, respectively). For comparison, its IC50 values for PKC isoforms alpha, gamma, delta, epsilon, zeta, and eta are 360, 300, 250, 600, >100,000, and 52 nM, respecti ... mehr
MW: 505 D
Formula: C28H28N4O3-HCl
Purity: >98%
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1 mg

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114 €

Cay13964-5
CAS: 169939-​93-​9
PKCbeta1 / PKCbeta2 Inhibitor Erklärungen der Abkürzungen ansehen.
LY333531 is a selective and potent inhibitor of PKCbeta1 and PKCbeta2 (IC50 = 4.7 and 5.9 nM, respectively). For comparison, its IC50 values for PKC isoforms alpha, gamma, delta, epsilon, zeta, and eta are 360, 300, 250, 600, >100,000, and 52 nM, respecti ... mehr
MW: 505 D
Formula: C28H28N4O3-HCl
Purity: >98%
Cayman
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5 mg

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370 €

Cay14006-1
CAS: 294646-​77-​8
CDK Inhibitor Erklärungen der Abkürzungen ansehen.
Cyclin-​dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-​CR8 is a second-​generation analog of (R)-​roscovitine (Item No. Cay10009569) that inhibits CDK1/cyclin B, CDK2/cyclin A ... mehr
MW: 431 D
Formula: C24H29N7O
Purity: >98%
Cayman
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1 mg

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64 €

Cay14006-5
CAS: 294646-​77-​8
CDK Inhibitor Erklärungen der Abkürzungen ansehen.
Cyclin-​dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. (R)-​CR8 is a second-​generation analog of (R)-​roscovitine (Item No. Cay10009569) that inhibits CDK1/cyclin B, CDK2/cyclin A ... mehr
MW: 431 D
Formula: C24H29N7O
Purity: >98%
Cayman
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5 mg

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191 €

Cay14155-10
CAS: 479-​41-​4
GSK-​3 inhibitor, CDK1 / 5 inhibitor Erklärungen der Abkürzungen ansehen.
Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-​inflammatory, anti-​tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-​ ... mehr
MW: 262 D
Formula: C16H10N2O2
Purity: >98%
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10 mg

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100 €

Cay14155-25
CAS: 479-​41-​4
GSK-​3 inhibitor, CDK1 / 5 inhibitor Erklärungen der Abkürzungen ansehen.
Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-​inflammatory, anti-​tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-​ ... mehr
MW: 262 D
Formula: C16H10N2O2
Purity: >98%
Cayman
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25 mg

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235 €

Cay14155-5
CAS: 479-​41-​4
GSK-​3 inhibitor, CDK1 / 5 inhibitor Erklärungen der Abkürzungen ansehen.
Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-​inflammatory, anti-​tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-​ ... mehr
MW: 262 D
Formula: C16H10N2O2
Purity: >98%
Cayman
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5 mg

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52 €

Cay14155-50
CAS: 479-​41-​4
GSK-​3 inhibitor, CDK1 / 5 inhibitor Erklärungen der Abkürzungen ansehen.
Indirubin is a natural product originally extracted from roots and leaves of the Indigo plant (I. tinctoria), used in traditional Chinese medicine for anti-​inflammatory, anti-​tumor, and neuroprotective effects. Indirubin inhibits glycogen synthase kinase-​ ... mehr
MW: 262 D
Formula: C16H10N2O2
Purity: >98%
Cayman
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50 mg

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418 €

Cay14156-10
CAS: 1670-​87-​7
MAP kinase p38alpha  /  p38beta inhibitor Erklärungen der Abkürzungen ansehen.
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-​1, and MAPKAPK-​2, when tested i ... mehr
MW: 160 D
Formula: C9H8N2O
Purity: >97%
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10 mg

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57 €

Cay14156-25
CAS: 1670-​87-​7
MAP kinase p38alpha  /  p38beta inhibitor Erklärungen der Abkürzungen ansehen.
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-​1, and MAPKAPK-​2, when tested i ... mehr
MW: 160 D
Formula: C9H8N2O
Purity: >97%
Cayman
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25 mg

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135 €

Cay14156-5
CAS: 1670-​87-​7
MAP kinase p38alpha  /  p38beta inhibitor Erklärungen der Abkürzungen ansehen.
SD 169 is a selective ATP competitive inhibitor of the MAP kinases p38alpha (IC50 = 3.2 nM) and p38beta (IC50 = 122 nM). It has no inhibitory effect against a panel of other kinases, including p38gamma MAP kinase, ERK2, JNK-​1, and MAPKAPK-​2, when tested i ... mehr
MW: 160 D
Formula: C9H8N2O
Purity: >97%
Cayman
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5 mg

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34 €

Cay14185-10
CAS: 1223001-​51-​1
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-​fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-​fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr
MW: 432 D
Formula: C24H15F3N4O
Purity: >98%
Cayman
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10 mg

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176 €

Cay14185-25
CAS: 1223001-​51-​1
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-​fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-​fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr
MW: 432 D
Formula: C24H15F3N4O
Purity: >98%
Cayman
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25 mg

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413 €

Cay14185-5
CAS: 1223001-​51-​1
mTOR inhibitor Erklärungen der Abkürzungen ansehen.
Torin 2 is a potent and selective inhibitor of cellular mTOR activity (EC50 = 0.3 nM). It shows more than 800-​fold selectivity for mTOR over PI3K (EC50 = 200 nM) and greater than 100-​fold binding selectivity relative to 440 other protein kinases. Torin 2 ... mehr
MW: 432 D
Formula: C24H15F3N4O
Purity: >98%
Cayman
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5 mg

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110 €

Cay14399-10
CAS: 1314118-​94-​9
MK2 inhibitor Erklärungen der Abkürzungen ansehen.
Activation of the p38/mitogen-​activated protein kinase-​activated protein kinase 2 (MAPKAPK2 or MK2) pathway has been implicated in promoting pro-​inflammatory cytokine production and related inflammatory diseases. MK 25 is a highly selective, non-​ATP compe ... mehr
MW: 509 D
Formula: C27H25ClN4O2 - HCl
Purity: >95%
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10 mg

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144 €

Cay14399-25
CAS: 1314118-​94-​9
MK2 inhibitor Erklärungen der Abkürzungen ansehen.
Activation of the p38/mitogen-​activated protein kinase-​activated protein kinase 2 (MAPKAPK2 or MK2) pathway has been implicated in promoting pro-​inflammatory cytokine production and related inflammatory diseases. MK 25 is a highly selective, non-​ATP compe ... mehr
MW: 509 D
Formula: C27H25ClN4O2 - HCl
Purity: >95%
Cayman
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25 mg

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340 €

Cay14399-5
CAS: 1314118-​94-​9
MK2 inhibitor Erklärungen der Abkürzungen ansehen.
Activation of the p38/mitogen-​activated protein kinase-​activated protein kinase 2 (MAPKAPK2 or MK2) pathway has been implicated in promoting pro-​inflammatory cytokine production and related inflammatory diseases. MK 25 is a highly selective, non-​ATP compe ... mehr
MW: 509 D
Formula: C27H25ClN4O2 - HCl
Purity: >95%
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5 mg

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75 €

Cay14428-1
CAS: 237430-​03-​4
CDK inhibitor, GSK-​3beta inhibitor Erklärungen der Abkürzungen ansehen.
Alsterpaullone is a derivative of kenpaullone (Item No. Cay10010239), an ATP-​competitive inhibitor of several cyclin-​dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK-​3beta). With slightly improved potency over kenpaullone, alsterpau ... mehr
MW: 293 D
Formula: C16H11N3O3
Purity: >98%
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1 mg

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64 €

Cay14428-5
CAS: 237430-​03-​4
CDK inhibitor, GSK-​3beta inhibitor Erklärungen der Abkürzungen ansehen.
Alsterpaullone is a derivative of kenpaullone (Item No. Cay10010239), an ATP-​competitive inhibitor of several cyclin-​dependent kinases (CDKs) as well as glycogen synthase kinase 3beta (GSK-​3beta). With slightly improved potency over kenpaullone, alsterpau ... mehr
MW: 293 D
Formula: C16H11N3O3
Purity: >98%
Cayman
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5 mg

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288 €

Cay14453-10
CAS: 17374-​26-​4
Casein kinase 2 inhibitor Erklärungen der Abkürzungen ansehen.
TBB is an ATP/GTP-​competitive inhibitor of casein kinase 2 (CK2, IC50 = 900 µM for rat liver CK2). It less potently inhibits CCK2/cyclin A, GSK3beta, and phosphorylase kinase (IC50 = 15.6, 11.2, and 8.7 mM, respectively). It is much less effective against ... mehr
MW: 434 D
Formula: C6HBr4N3
Purity: >98%
Cayman
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10 mg

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66 €

Cay14453-25
CAS: 17374-​26-​4
Casein kinase 2 inhibitor Erklärungen der Abkürzungen ansehen.
TBB is an ATP/GTP-​competitive inhibitor of casein kinase 2 (CK2, IC50 = 900 µM for rat liver CK2). It less potently inhibits CCK2/cyclin A, GSK3beta, and phosphorylase kinase (IC50 = 15.6, 11.2, and 8.7 mM, respectively). It is much less effective against ... mehr
MW: 434 D
Formula: C6HBr4N3
Purity: >98%
Cayman
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25 mg

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122 €

Cay14453-5
CAS: 17374-​26-​4
Casein kinase 2 inhibitor Erklärungen der Abkürzungen ansehen.
TBB is an ATP/GTP-​competitive inhibitor of casein kinase 2 (CK2, IC50 = 900 µM for rat liver CK2). It less potently inhibits CCK2/cyclin A, GSK3beta, and phosphorylase kinase (IC50 = 15.6, 11.2, and 8.7 mM, respectively). It is much less effective against ... mehr
MW: 434 D
Formula: C6HBr4N3
Purity: >98%
Cayman
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5 mg

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35 €

Cay14453-50
CAS: 17374-​26-​4
Casein kinase 2 inhibitor Erklärungen der Abkürzungen ansehen.
TBB is an ATP/GTP-​competitive inhibitor of casein kinase 2 (CK2, IC50 = 900 µM for rat liver CK2). It less potently inhibits CCK2/cyclin A, GSK3beta, and phosphorylase kinase (IC50 = 15.6, 11.2, and 8.7 mM, respectively). It is much less effective against ... mehr
MW: 434 D
Formula: C6HBr4N3
Purity: >98%
Cayman
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50 mg

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226 €

Cay14588-10
CAS: 950912-​80-​8
CK1 epsilon and CK1 delta inhibitor Erklärungen der Abkürzungen ansehen.
The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-​670462 is a potent inhibitor of the CK1 isoforms CK1epsilon and CK1delta (IC50 = 7.7 and 14 nM, respectiv ... mehr
MW: 410 D
Formula: C19H20FN5 - 2HCl
Purity: >99%
Cayman
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10 mg

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145 €

Cay14588-50
CAS: 950912-​80-​8
CK1 epsilon and CK1 delta inhibitor Erklärungen der Abkürzungen ansehen.
The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-​670462 is a potent inhibitor of the CK1 isoforms CK1epsilon and CK1delta (IC50 = 7.7 and 14 nM, respectiv ... mehr
MW: 410 D
Formula: C19H20FN5 - 2HCl
Purity: >99%
Cayman
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50 mg

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616 €

Cay14589-100
CAS: 56-​25-​7
Protein phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Cantharidin is a natural toxin produced by blister beetles that moderately inhibits protein phosphatases (PP) 1 (IC50 = 1.7 µM) and PP2A (IC50 = 0.2 µM) and only weakly inhibits the activity of PP2B (IC50 > 1 mM). It has been shown to stimulate cell cycle ... mehr
MW: 196 D
Formula: C10H12O4
Purity: >98%
Cayman
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100 mg

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125 €

Cay14589-25
CAS: 56-​25-​7
Protein phosphatase inhibitor Erklärungen der Abkürzungen ansehen.
Cantharidin is a natural toxin produced by blister beetles that moderately inhibits protein phosphatases (PP) 1 (IC50 = 1.7 µM) and PP2A (IC50 = 0.2 µM) and only weakly inhibits the activity of PP2B (IC50 > 1 mM). It has been shown to stimulate cell cycle ... mehr
MW: 196 D
Formula: C10H12O4
Purity: >98%
Cayman
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25 mg

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42 €

Cay14704-10
neu

CAS: 487021-​52-​3
ATP-​competitive inhibitor glycogen synthase kinase 3beta inhibitor Erklärungen der Abkürzungen ansehen.
GSK-​3beta Inhibitor VIII is an ATP-​competitive inhibitor of the serine/threonine kinase, glycogen synthase kinase 3beta (Ki = 38 nM, IC50 = 104 nM). It does not significantly inhibit the closely related cyclin-​dependent kinase (Cdk)2 or Cdk5 (Kis = > 100 ... mehr
MW: 308 D
Formula: C12H12N4O4S
Purity: >98%
Cayman
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10 mg

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128 €

Cay14704-5
neu

CAS: 487021-​52-​3
ATP-​competitive inhibitor glycogen synthase kinase 3beta inhibitor Erklärungen der Abkürzungen ansehen.
GSK-​3beta Inhibitor VIII is an ATP-​competitive inhibitor of the serine/threonine kinase, glycogen synthase kinase 3beta (Ki = 38 nM, IC50 = 104 nM). It does not significantly inhibit the closely related cyclin-​dependent kinase (Cdk)2 or Cdk5 (Kis = > 100 ... mehr
MW: 308 D
Formula: C12H12N4O4S
Purity: >98%
Cayman
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5 mg

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67 €

Cay14704-50
neu

CAS: 487021-​52-​3
ATP-​competitive inhibitor glycogen synthase kinase 3beta inhibitor Erklärungen der Abkürzungen ansehen.
GSK-​3beta Inhibitor VIII is an ATP-​competitive inhibitor of the serine/threonine kinase, glycogen synthase kinase 3beta (Ki = 38 nM, IC50 = 104 nM). It does not significantly inhibit the closely related cyclin-​dependent kinase (Cdk)2 or Cdk5 (Kis = > 100 ... mehr
MW: 308 D
Formula: C12H12N4O4S
Purity: >98%
Cayman
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50 mg

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538 €

Cay14708-1
CAS: 702674-​56-​4
PDK1 inhibitor Erklärungen der Abkürzungen ansehen.
3-​Phosphoinositide-​dependent protein kinase 1 (PDK1) is a serine-​threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK) B, PKA, and certain isoforms of PKC. BX-​912 is a potent, ATP-​competitive inhibitor ... mehr
MW: 471 D
Formula: C20H23BrN8O
Purity: >98%
Cayman
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1 mg

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64 €

Cay14708-10
CAS: 702674-​56-​4
PDK1 inhibitor Erklärungen der Abkürzungen ansehen.
3-​Phosphoinositide-​dependent protein kinase 1 (PDK1) is a serine-​threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK) B, PKA, and certain isoforms of PKC. BX-​912 is a potent, ATP-​competitive inhibitor ... mehr
MW: 471 D
Formula: C20H23BrN8O
Purity: >98%
Cayman
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10 mg

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191 €

Cay14708-25
CAS: 702674-​56-​4
PDK1 inhibitor Erklärungen der Abkürzungen ansehen.
3-​Phosphoinositide-​dependent protein kinase 1 (PDK1) is a serine-​threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK) B, PKA, and certain isoforms of PKC. BX-​912 is a potent, ATP-​competitive inhibitor ... mehr
MW: 471 D
Formula: C20H23BrN8O
Purity: >98%
Cayman
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25 mg

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399 €

Cay14708-5
CAS: 702674-​56-​4
PDK1 inhibitor Erklärungen der Abkürzungen ansehen.
3-​Phosphoinositide-​dependent protein kinase 1 (PDK1) is a serine-​threonine kinase that phosphorylates and activates a range of other kinases, including protein kinase (PK) B, PKA, and certain isoforms of PKC. BX-​912 is a potent, ATP-​competitive inhibitor ... mehr
MW: 471 D
Formula: C20H23BrN8O
Purity: >98%
Cayman
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5 mg

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128 €

Cay14749-100
neu

CAS: 87810-​56-​8
PP2A / PP4 inhibitor Erklärungen der Abkürzungen ansehen.
Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 µM, respectively) and does not inhibit PP2B. Thro ... mehr
MW: 452 D
Formula: C19H26O9P - Na
Purity: >95%
Cayman
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100 µg

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347 €

Cay14749-500
neu

CAS: 87810-​56-​8
PP2A / PP4 inhibitor Erklärungen der Abkürzungen ansehen.
Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 µM, respectively) and does not inhibit PP2B. Thro ... mehr
MW: 452 D
Formula: C19H26O9P - Na
Purity: >95%
Cayman
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500 µg

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1128 €

Cay14759-10
CAS: 42521-​82-​4
PAK1 inhibitor Erklärungen der Abkürzungen ansehen.
p21-​activated kinase 1 (PAK1) is a member of a family non-​receptor serine/threonine kinases that are vital to normal cell function. Binding of various upstream partners to PAK1 results in release of an autoinhibitory domain that blocks activity of the kin ... mehr
MW: 350 D
Formula: C20H14O2S2
Purity: >95%
Cayman
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10 mg

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84 €

Cay14759-25
CAS: 42521-​82-​4
PAK1 inhibitor Erklärungen der Abkürzungen ansehen.
p21-​activated kinase 1 (PAK1) is a member of a family non-​receptor serine/threonine kinases that are vital to normal cell function. Binding of various upstream partners to PAK1 results in release of an autoinhibitory domain that blocks activity of the kin ... mehr
MW: 350 D
Formula: C20H14O2S2
Purity: >95%
Cayman
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25 mg

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196 €

Cay14759-5
CAS: 42521-​82-​4
PAK1 inhibitor Erklärungen der Abkürzungen ansehen.
p21-​activated kinase 1 (PAK1) is a member of a family non-​receptor serine/threonine kinases that are vital to normal cell function. Binding of various upstream partners to PAK1 results in release of an autoinhibitory domain that blocks activity of the kin ... mehr
MW: 350 D
Formula: C20H14O2S2
Purity: >95%
Cayman
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5 mg

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52 €

Cay14759-50
CAS: 42521-​82-​4
PAK1 inhibitor Erklärungen der Abkürzungen ansehen.
p21-​activated kinase 1 (PAK1) is a member of a family non-​receptor serine/threonine kinases that are vital to normal cell function. Binding of various upstream partners to PAK1 results in release of an autoinhibitory domain that blocks activity of the kin ... mehr
MW: 350 D
Formula: C20H14O2S2
Purity: >95%
Cayman
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50 mg

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313 €

Cay14794-1
CAS: 446859-​33-​2
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-​beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-​beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhib ... mehr
MW: 287 D
Formula: C17H13N5
Purity: >98%
Cayman
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1 mg

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41 €

Cay14794-10
CAS: 446859-​33-​2
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-​beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-​beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhib ... mehr
MW: 287 D
Formula: C17H13N5
Purity: >98%
Cayman
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10 mg

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143 €

Cay14794-25
CAS: 446859-​33-​2
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-​beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-​beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhib ... mehr
MW: 287 D
Formula: C17H13N5
Purity: >98%
Cayman
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25 mg

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305 €

Cay14794-5
CAS: 446859-​33-​2
ALK5 inhibitor Erklärungen der Abkürzungen ansehen.
ALK5 inhibitor II is a cell permeable, selective inhibitor of the TGF-​beta type 1 activin like kinase receptor ALK5 (IC50s = 4, 18, and 23 nM for ALK5 autophosphorylation, TGF-​beta cellular assay, and ALK5 binding in HepG2 cells, respectively). This inhib ... mehr
MW: 287 D
Formula: C17H13N5
Purity: >98%
Cayman
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5 mg

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81 €

Cay14862-1
CAS: 1049743-​58-​9
IKKbeta inhibitor Erklärungen der Abkürzungen ansehen.
Nuclear factor-​kappaB (NF-​kappaB) is a protein complex which modulates gene transcription relevant to cellular responses to inflammation, stress, infection, and other factors. The inhibitor of NF-​kappaB kinase beta (IKKbeta), in complex with IKKa and IKKg ... mehr
MW: 395 D
Formula: C17H11ClN4O - 2HCl
Purity: >98%
Cayman
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1 mg

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56 €

Cay14862-5
CAS: 1049743-​58-​9
IKKbeta inhibitor Erklärungen der Abkürzungen ansehen.
Nuclear factor-​kappaB (NF-​kappaB) is a protein complex which modulates gene transcription relevant to cellular responses to inflammation, stress, infection, and other factors. The inhibitor of NF-​kappaB kinase beta (IKKbeta), in complex with IKKa and IKKg ... mehr
MW: 395 D
Formula: C17H11ClN4O - 2HCl
Purity: >98%
Cayman
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5 mg

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145 €

Cay14862-500
CAS: 1049743-​58-​9
IKKbeta inhibitor Erklärungen der Abkürzungen ansehen.
Nuclear factor-​kappaB (NF-​kappaB) is a protein complex which modulates gene transcription relevant to cellular responses to inflammation, stress, infection, and other factors. The inhibitor of NF-​kappaB kinase beta (IKKbeta), in complex with IKKa and IKKg ... mehr
MW: 395 D
Formula: C17H11ClN4O - 2HCl
Purity: >98%
Cayman
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500 µg

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29 €

Cay14863-1
CAS: 925681-​41-​0
Akt phosphorylation inhibitor Erklärungen der Abkürzungen ansehen.
Akt functions as a key component in multiple signaling pathways to promote cell survival by mediating resistance to apoptosis. Akt inhibitor X is a cell permeable phenoxazine derivative that suppresses insulin-​like growth factor 1 (IGF-​1)-​stimulated phosp ... mehr
MW: 381 D
Formula: C20H25ClN2O - HCl
Purity: >95%
Cayman
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1 mg

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75 €

Cay14863-10
CAS: 925681-​41-​0
Akt phosphorylation inhibitor Erklärungen der Abkürzungen ansehen.
Akt functions as a key component in multiple signaling pathways to promote cell survival by mediating resistance to apoptosis. Akt inhibitor X is a cell permeable phenoxazine derivative that suppresses insulin-​like growth factor 1 (IGF-​1)-​stimulated phosp ... mehr
MW: 381 D
Formula: C20H25ClN2O - HCl
Purity: >95%
Cayman
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10 mg

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415 €

Cay14863-5
CAS: 925681-​41-​0
Akt phosphorylation inhibitor Erklärungen der Abkürzungen ansehen.
Akt functions as a key component in multiple signaling pathways to promote cell survival by mediating resistance to apoptosis. Akt inhibitor X is a cell permeable phenoxazine derivative that suppresses insulin-​like growth factor 1 (IGF-​1)-​stimulated phosp ... mehr
MW: 381 D
Formula: C20H25ClN2O - HCl
Purity: >95%
Cayman
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5 mg

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264 €

Cay14870-1
CAS: 612847-​09-​3
AKT1  /  AKT2 inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (Akt1, 2, 3, also known as protein kinase B isoforms PKB alpha, beta, gamma) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent, allosteric inhibitor of Akt1 ... mehr
MW: 551 D
Formula: C34H29N7O
Purity: >98%
Cayman
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1 mg

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128 €

Cay14870-10
CAS: 612847-​09-​3
AKT1  /  AKT2 inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (Akt1, 2, 3, also known as protein kinase B isoforms PKBa, ß, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent, allosteric inhibitor of Akt1 and Akt2 (IC ... mehr
MW: 551 D
Formula: C34H29N7O
Purity: >98%
Cayman
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10 mg

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320 €

Cay14870-5
CAS: 612847-​09-​3
AKT1  /  AKT2 inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (Akt1, 2, 3, also known as protein kinase B isoforms PKBa, ß, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent, allosteric inhibitor of Akt1 and Akt2 (IC ... mehr
MW: 551 D
Formula: C34H29N7O
Purity: >98%
Cayman
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5 mg

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201 €

Cay14870-500
CAS: 612847-​09-​3
AKT1  /  AKT2 inhibitor Erklärungen der Abkürzungen ansehen.
Three related forms of the kinase Akt (Akt1, 2, 3, also known as protein kinase B isoforms PKBa, ß, ?) modulate cell proliferation, metabolism, and survival as well as angiogenesis. Akt inhibitor VIII is a potent, allosteric inhibitor of Akt1 and Akt2 (IC ... mehr
MW: 551 D
Formula: C34H29N7O
Purity: >98%
Cayman
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500 µg

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80 €

Cay14881-1
CAS: 503468-​95-​9
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
DNA-​dependent protein kinase (DNA-​PK) catalyzes nonhomologous end-​joining, which is required to repair lethal DNA double-​strand breaks. Because cells that are defective in DNA double-​strand break repair are highly sensitive to ionizing radiation and topoi ... mehr
MW: 413 D
Formula: C25H19NO3S
Purity: >98%
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1 mg

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29 €

Cay14881-10
CAS: 503468-​95-​9
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
DNA-​dependent protein kinase (DNA-​PK) catalyzes nonhomologous end-​joining, which is required to repair lethal DNA double-​strand breaks. Because cells that are defective in DNA double-​strand break repair are highly sensitive to ionizing radiation and topoi ... mehr
MW: 413 D
Formula: C25H19NO3S
Purity: >98%
Cayman
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10 mg

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131 €

Cay14881-25
CAS: 503468-​95-​9
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
DNA-​dependent protein kinase (DNA-​PK) catalyzes nonhomologous end-​joining, which is required to repair lethal DNA double-​strand breaks. Because cells that are defective in DNA double-​strand break repair are highly sensitive to ionizing radiation and topoi ... mehr
MW: 413 D
Formula: C25H19NO3S
Purity: >98%
Cayman
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25 mg

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290 €

Cay14881-5
CAS: 503468-​95-​9
DNA-​PK inhibitor Erklärungen der Abkürzungen ansehen.
DNA-​dependent protein kinase (DNA-​PK) catalyzes nonhomologous end-​joining, which is required to repair lethal DNA double-​strand breaks. Because cells that are defective in DNA double-​strand break repair are highly sensitive to ionizing radiation and topoi ... mehr
MW: 413 D
Formula: C25H19NO3S
Purity: >98%
Cayman
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5 mg

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73 €

Cay15015-1
CAS: 942487-​16-​3
Aurora kinase inhibitor, kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-​03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr
MW: 474 D
Formula: C23H25F3N6O2
Purity: >95%
Cayman
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1 mg

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41 €

Cay15015-10
CAS: 942487-​16-​3
Aurora kinase inhibitor, kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-​03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr
MW: 474 D
Formula: C23H25F3N6O2
Purity: >95%
Cayman
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10 mg

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305 €

Cay15015-5
CAS: 942487-​16-​3
Aurora kinase inhibitor, kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-​03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr
MW: 474 D
Formula: C23H25F3N6O2
Purity: >95%
Cayman
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5 mg

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173 €

Cay15015-50
CAS: 942487-​16-​3
Aurora kinase inhibitor, kinase inhibitor Erklärungen der Abkürzungen ansehen.
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. PF-​03814735 is a reversible inhibitor of both Aurora A and Aurora B kinases with IC50 values of 0.8 and 5 nM, respectively, in in vitro activit ... mehr
MW: 474 D
Formula: C23H25F3N6O2
Purity: >95%
Cayman
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50 mg

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711 €

Cay15018-10
CAS: 1255517-​76-​0
S6K1 inhibitor Erklärungen der Abkürzungen ansehen.
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-​04708671 is a specific, cell-​permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr
MW: 390 D
Formula: C19H21F3N6
Purity: >98%
Cayman
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10 mg

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87 €

Cay15018-100
CAS: 1255517-​76-​0
S6K1 inhibitor Erklärungen der Abkürzungen ansehen.
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-​04708671 is a specific, cell-​permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr
MW: 390 D
Formula: C19H21F3N6
Purity: >98%
Cayman
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100 mg

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696 €

Cay15018-25
CAS: 1255517-​76-​0
S6K1 inhibitor Erklärungen der Abkürzungen ansehen.
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-​04708671 is a specific, cell-​permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr
MW: 390 D
Formula: C19H21F3N6
Purity: >98%
Cayman
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25 mg

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206 €

Cay15018-50
CAS: 1255517-​76-​0
S6K1 inhibitor Erklärungen der Abkürzungen ansehen.
P70 ribosomal S6 kinase (S6K1) is a serine/threonine kinase which is activated by insulin and growth factors through PI3K and mTORC1 signaling pathways. PF-​04708671 is a specific, cell-​permeable inhibitor of S6K1 (IC50 = 160 nM). It does not inhibit S6K2, ... mehr
MW: 390 D
Formula: C19H21F3N6
Purity: >98%
Cayman
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50 mg

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392 €

Cay15115-1
CAS: 507475-​17-​4
IkappaB kinase-​2 inhibitor Erklärungen der Abkürzungen ansehen.
TPCA-​1 is a selective inhibitor of IkappaB kinase-​2 (IC50s = 17.9 nM and 0.40 µM for IKK-​2 and -​1, respectively). Furthermore, it displays greater than 550-​fold selectivity over other kinases and enzymes including, p38, MAPK, COX, and JNK. TPCA-​1 inhibits ... mehr
MW: 279 D
Formula: C12H10FN3O2S
Purity: >98%
Cayman
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1 mg

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89 €

Cay15115-10
CAS: 507475-​17-​4
IkappaB kinase-​2 inhibitor Erklärungen der Abkürzungen ansehen.
TPCA-​1 is a selective inhibitor of IkappaB kinase-​2 (IC50s = 17.9 nM and 0.40 µM for IKK-​2 and -​1, respectively). Furthermore, it displays greater than 550-​fold selectivity over other kinases and enzymes including, p38, MAPK, COX, and JNK. TPCA-​1 inhibits ... mehr
MW: 279 D
Formula: C12H10FN3O2S
Purity: >98%
Cayman
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10 mg

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191 €

Cay15115-5
CAS: 507475-​17-​4
IkappaB kinase-​2 inhibitor Erklärungen der Abkürzungen ansehen.
TPCA-​1 is a selective inhibitor of IkappaB kinase-​2 (IC50s = 17.9 nM and 0.40 µM for IKK-​2 and -​1, respectively). Furthermore, it displays greater than 550-​fold selectivity over other kinases and enzymes including, p38, MAPK, COX, and JNK. TPCA-​1 inhibits ... mehr
MW: 279 D
Formula: C12H10FN3O2S
Purity: >98%
Cayman
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5 mg

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128 €

Cay15115-500
CAS: 507475-​17-​4
IkappaB kinase-​2 inhibitor Erklärungen der Abkürzungen ansehen.
TPCA-​1 is a selective inhibitor of IkappaB kinase-​2 (IC50s = 17.9 nM and 0.40 µM for IKK-​2 and -​1, respectively). Furthermore, it displays greater than 550-​fold selectivity over other kinases and enzymes including, p38, MAPK, COX, and JNK. TPCA-​1 inhibits ... mehr
MW: 279 D
Formula: C12H10FN3O2S
Purity: >98%
Cayman
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500 µg

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64 €

Cay15264-1
CAS: 501437-​28-​1
RSK1 / 2 / 3 / 4 inhibitor Erklärungen der Abkürzungen ansehen.
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-​D1870 is a cell permeable, ATP-​competitive inhibitor of the four vertebrate isoforms of RSK ... mehr
MW: 391 D
Formula: C19H23F2N5O2
Purity: >98%
Cayman
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1 mg

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51 €

Cay15264-10
CAS: 501437-​28-​1
RSK1 / 2 / 3 / 4 inhibitor Erklärungen der Abkürzungen ansehen.
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-​D1870 is a cell permeable, ATP-​competitive inhibitor of the four vertebrate isoforms of RSK ... mehr
MW: 391 D
Formula: C19H23F2N5O2
Purity: >98%
Cayman
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10 mg

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306 €

Cay15264-5
CAS: 501437-​28-​1
RSK1 / 2 / 3 / 4 inhibitor Erklärungen der Abkürzungen ansehen.
The 90 kDa ribosomal S6 kinases (RSKs) are a group of serine/threonine kinases involved in diverse cellular processes, including growth, survival, and motility. BI-​D1870 is a cell permeable, ATP-​competitive inhibitor of the four vertebrate isoforms of RSK ... mehr
MW: 391 D
Formula: C19H23F2N5O2
Purity: >98%
Cayman
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5 mg

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191 €

Cay15312-1
CAS: 700874-​72-​2
TGFBR1 inhibitor Erklärungen der Abkürzungen ansehen.
LY2157299 is a small molecule inhibitor of the TGF-​beta receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-​beta signaling in chemotherapy-​induced expansion of cancer stem-​like cells in triple negative breast cancer cell lines ... mehr
MW: 369 D
Formula: C22H19N5O
Cayman
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1 mg

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45 €

Cay15312-10
CAS: 700874-​72-​2
TGFBR1 inhibitor Erklärungen der Abkürzungen ansehen.
LY2157299 is a small molecule inhibitor of the TGF-​beta receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-​beta signaling in chemotherapy-​induced expansion of cancer stem-​like cells in triple negative breast cancer cell lines ... mehr
MW: 369 D
Formula: C22H19N5O
Cayman
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10 mg

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295 €

Cay15312-5
CAS: 700874-​72-​2
TGFBR1 inhibitor Erklärungen der Abkürzungen ansehen.
LY2157299 is a small molecule inhibitor of the TGF-​beta receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-​beta signaling in chemotherapy-​induced expansion of cancer stem-​like cells in triple negative breast cancer cell lines ... mehr
MW: 369 D
Formula: C22H19N5O
Cayman
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5 mg

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181 €

Cay15312-50
CAS: 700874-​72-​2
TGFBR1 inhibitor Erklärungen der Abkürzungen ansehen.
LY2157299 is a small molecule inhibitor of the TGF-​beta receptor type 1 kinase (IC50 = 56 nM). It has been used to study the role of TGF-​beta signaling in chemotherapy-​induced expansion of cancer stem-​like cells in triple negative breast cancer cell lines ... mehr
MW: 369 D
Formula: C22H19N5O
Cayman
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50 mg

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792 €

Cay15317-10
neu

CAS: 638156-​11-​3
Protein kinase D  ( PKD )  inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein t ... mehr
MW: 396 D
Formula: C22H21ClN2O3
Cayman
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10 mg

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136 €

Cay15317-25
neu

CAS: 638156-​11-​3
Protein kinase D  ( PKD )  inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein t ... mehr
MW: 396 D
Formula: C22H21ClN2O3
Cayman
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25 mg

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320 €

Cay15317-5
neu

CAS: 638156-​11-​3
Protein kinase D  ( PKD )  inhibitor Erklärungen der Abkürzungen ansehen.
Protein kinase D (PKD) is a serine/threonine protein kinase that is activated by diacylglycerol, commonly downstream of PKC signaling. The three human PKD isoforms target a variety of proteins to alter cell proliferation, survival, invasion, and protein t ... mehr
MW: 396 D
Formula: C22H21ClN2O3
Cayman
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5 mg

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80 €

Cay15323-1
neu

CAS: 608512-​97-​6
EIF2AK2 inhibitor Erklärungen der Abkürzungen ansehen.
The activity of double-​stranded RNA-​activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit a (eIF2a), blocking translation and ... mehr
MW: 268 D
Formula: C13H8N4OS
Purity: >95%
Cayman
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1 mg

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29 €

Cay15323-10
neu

CAS: 608512-​97-​6
EIF2AK2 inhibitor Erklärungen der Abkürzungen ansehen.
The activity of double-​stranded RNA-​activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit a (eIF2a), blocking translation and ... mehr
MW: 268 D
Formula: C13H8N4OS
Purity: >95%
Cayman
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10 mg

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131 €

Cay15323-25
neu

CAS: 608512-​97-​6
EIF2AK2 inhibitor Erklärungen der Abkürzungen ansehen.
The activity of double-​stranded RNA-​activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit a (eIF2a), blocking translation and ... mehr
MW: 268 D
Formula: C13H8N4OS
Purity: >95%
Cayman
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25 mg

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290 €

Cay15323-5
neu

CAS: 608512-​97-​6
EIF2AK2 inhibitor Erklärungen der Abkürzungen ansehen.
The activity of double-​stranded RNA-​activated protein kinase (PKR) is altered by viral infection as well as by various neuropathologies. A primary phosphorylation target of PKR is eukaryotic initiation factor 2 subunit a (eIF2a), blocking translation and ... mehr
MW: 268 D
Formula: C13H8N4OS
Purity: >95%
Cayman
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5 mg

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73 €

Cay15383-100
CAS: 121263-​19-​2
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Calphostin C is a metabolite of the fungus C. cladosporioides that specifically inhibits protein kinase C (PKC) (IC50 = 50 nM versus an IC50 > 50 µM for PKA) by competing at the binding site for diacylglycerol and phorbol esters. As a polycyclic hydrocarb ... mehr
MW: 790 D
Formula: C44H38O14
Cayman
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100 µg

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114 €

Cay15383-500
CAS: 121263-​19-​2
PKC inhibitor Erklärungen der Abkürzungen ansehen.
Calphostin C is a metabolite of the fungus C. cladosporioides that specifically inhibits protein kinase C (PKC) (IC50 = 50 nM versus an IC50 > 50 µM for PKA) by competing at the binding site for diacylglycerol and phorbol esters. As a polycyclic hydrocarb ... mehr
MW: 790 D
Formula: C44H38O14
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500 µg

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512 €

Cay15399-1
neu

CAS: 6754-​58-​1
PDPK1 inhibitor Erklärungen der Abkürzungen ansehen.
Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-​2-​related factor 2 pathway. It inhibits phosp ... mehr
MW: 354 D
Formula: C21H22O5
Purity: >98%
Cayman
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1 mg

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29 €

Cay15399-10
neu

CAS: 6754-​58-​1
PDPK1 inhibitor Erklärungen der Abkürzungen ansehen.
Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-​2-​related factor 2 pathway. It inhibits phosp ... mehr
MW: 354 D
Formula: C21H22O5
Purity: >98%
Cayman
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10 mg

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116 €

Cay15399-25
neu

CAS: 6754-​58-​1
PDPK1 inhibitor Erklärungen der Abkürzungen ansehen.
Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-​2-​related factor 2 pathway. It inhibits phosp ... mehr
MW: 354 D
Formula: C21H22O5
Purity: >98%
Cayman
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25 mg

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254 €

Cay15399-5
neu

CAS: 6754-​58-​1
PDPK1 inhibitor Erklärungen der Abkürzungen ansehen.
Xanthohumol is a natural prenylated chalcone isolated from the hop plant, H. lupulus. Xanthohumol and its metabolites induce protective detoxification enzymes, at least in part via the nuclear factor erythroid-​2-​related factor 2 pathway. It inhibits phosp ... mehr
MW: 354 D
Formula: C21H22O5
Purity: >98%
Cayman
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5 mg

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80 €

Cay15406-1
neu

CAS: 1143532-​39-​1
AKT inhibitor