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Cay700100-96
COX inhibitor screening Erklärungen der Abkürzungen ansehen.
This COX Fluorescent Inhibitor Screening Assay provides a convenient fluorescence-based method for screening ovine COX-1 and human recombinant COX-2 for isozyme-specific inhibitors. The assay utilizes the peroxidase component of COXs.
Cayman
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96 wells

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430 €

Cay10008672-100
CAS: 169590-​42-​5
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Celecoxib is an anti-​inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-​2 (COX-​2) (IC50s = 22.9 and 0.05 µM for COX-​1 and COX-​2, respectively). While it was initially hailed as a major therapeutic advance in t ... mehr
MW: 381 D
Formula: C17H14F3N3O2S
Purity: >98%
Cayman
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100 mg

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78 €

Cay10008672-250
CAS: 169590-​42-​5
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Celecoxib is an anti-​inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-​2 (COX-​2) (IC50s = 22.9 and 0.05 µM for COX-​1 and COX-​2, respectively). While it was initially hailed as a major therapeutic advance in t ... mehr
MW: 381 D
Formula: C17H14F3N3O2S
Purity: >98%
Cayman
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250 mg

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183 €

Cay10008672-50
CAS: 169590-​42-​5
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Celecoxib is an anti-​inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-​2 (COX-​2) (IC50s = 22.9 and 0.05 µM for COX-​1 and COX-​2, respectively). While it was initially hailed as a major therapeutic advance in t ... mehr
MW: 381 D
Formula: C17H14F3N3O2S
Purity: >98%
Cayman
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50 mg

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41 €

Cay10010260-100
CAS: 162011-​90-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Rofecoxib is a non-​steroidal anti-​inflammatory drug that inhibits cyclooxygenase (COX)-​2 activity with 1,000-​fold selectivity over that of COX-​1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells). In in vivo rodent models, rofecoxib can inhibit carra ... mehr
MW: 314 D
Formula: C17H14O4S
Purity: >98%
Cayman
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100 mg

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56 €

Cay10010260-250
CAS: 162011-​90-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Rofecoxib is a non-​steroidal anti-​inflammatory drug that inhibits cyclooxygenase (COX)-​2 activity with 1,000-​fold selectivity over that of COX-​1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells). In in vivo rodent models, rofecoxib can inhibit carra ... mehr
MW: 314 D
Formula: C17H14O4S
Purity: >98%
Cayman
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250 mg

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92 €

Cay10010260-50
CAS: 162011-​90-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Rofecoxib is a non-​steroidal anti-​inflammatory drug that inhibits cyclooxygenase (COX)-​2 activity with 1,000-​fold selectivity over that of COX-​1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells). In in vivo rodent models, rofecoxib can inhibit carra ... mehr
MW: 314 D
Formula: C17H14O4S
Purity: >98%
Cayman
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50 mg

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29 €

Cay10010260-500
CAS: 162011-​90-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Rofecoxib is a non-​steroidal anti-​inflammatory drug that inhibits cyclooxygenase (COX)-​2 activity with 1,000-​fold selectivity over that of COX-​1 (IC50s = 26 nM and > 50 µM in human osteosarcoma cells). In in vivo rodent models, rofecoxib can inhibit carra ... mehr
MW: 314 D
Formula: C17H14O4S
Purity: >98%
Cayman
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500 mg

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174 €

Cay10277-1
CAS: 912758-​00-​0
COX-​1 inhibitor, COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
ATB-​337 is a hybrid molecule of an H2S donor and the NSAID diclofenac. In rats, diclofenac at 10-​50 µmol/kg caused significant gastrointestinal damage, whereas no damage was observed with ATB-​337 treatment at the same dose. ATB-​337 at 50 µmol/kg does not ... mehr
MW: 504 D
Formula: C32H15NCl2O2S3
Purity: >98%
Cayman
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1 mg

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32 €

Cay10277-10
CAS: 912758-​00-​0
COX-​1 inhibitor, COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
ATB-​337 is a hybrid molecule of an H2S donor and the NSAID diclofenac. In rats, diclofenac at 10-​50 µmol/kg caused significant gastrointestinal damage, whereas no damage was observed with ATB-​337 treatment at the same dose. ATB-​337 at 50 µmol/kg does not ... mehr
MW: 504 D
Formula: C32H15NCl2O2S3
Purity: >98%
Cayman
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10 mg

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260 €

Cay10277-5
CAS: 912758-​00-​0
COX-​1 inhibitor, COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
ATB-​337 is a hybrid molecule of an H2S donor and the NSAID diclofenac. In rats, diclofenac at 10-​50 µmol/kg caused significant gastrointestinal damage, whereas no damage was observed with ATB-​337 treatment at the same dose. ATB-​337 at 50 µmol/kg does not ... mehr
MW: 504 D
Formula: C32H15NCl2O2S3
Purity: >98%
Cayman
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5 mg

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146 €

Cay10277-50
CAS: 912758-​00-​0
COX-​1 inhibitor, COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
ATB-​337 is a hybrid molecule of an H2S donor and the NSAID diclofenac. In rats, diclofenac at 10-​50 µmol/kg caused significant gastrointestinal damage, whereas no damage was observed with ATB-​337 treatment at the same dose. ATB-​337 at 50 µmol/kg does not ... mehr
MW: 504 D
Formula: C32H15NCl2O2S3
Purity: >98%
Cayman
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50 mg

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1137 €

Cay14906-100
CAS: 71125-​38-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Meloxicam is a non-​steroidal anti-​inflammatory drug (NSAID) with selectivity for COX-​2 (IC50 = 11.8 µM) over COX-​1 (IC50 = 143 µM) in in vitro assays. It shows potent anti-​inflammatory, antipyretic, and analgesic effects with low gastrointestinal toxicity ... mehr
MW: 351 D
Formula: C14H13N3O4S2
Purity: >95%
Cayman
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100 mg

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75 €

Cay14906-25
CAS: 71125-​38-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Meloxicam is a non-​steroidal anti-​inflammatory drug (NSAID) with selectivity for COX-​2 (IC50 = 11.8 µM) over COX-​1 (IC50 = 143 µM) in in vitro assays. It shows potent anti-​inflammatory, antipyretic, and analgesic effects with low gastrointestinal toxicity ... mehr
MW: 351 D
Formula: C14H13N3O4S2
Purity: >95%
Cayman
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25 mg

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29 €

Cay14906-50
CAS: 71125-​38-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Meloxicam is a non-​steroidal anti-​inflammatory drug (NSAID) with selectivity for COX-​2 (IC50 = 11.8 µM) over COX-​1 (IC50 = 143 µM) in in vitro assays. It shows potent anti-​inflammatory, antipyretic, and analgesic effects with low gastrointestinal toxicity ... mehr
MW: 351 D
Formula: C14H13N3O4S2
Purity: >95%
Cayman
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50 mg

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52 €

Cay14906-500
CAS: 71125-​38-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Meloxicam is a non-​steroidal anti-​inflammatory drug (NSAID) with selectivity for COX-​2 (IC50 = 11.8 µM) over COX-​1 (IC50 = 143 µM) in in vitro assays. It shows potent anti-​inflammatory, antipyretic, and analgesic effects with low gastrointestinal toxicity ... mehr
MW: 351 D
Formula: C14H13N3O4S2
Purity: >95%
Cayman
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500 mg

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261 €

Cay460101-1 COX inhibitor screening assay COX-​2 (ovine)
COX inhibitor screening Erklärungen der Abkürzungen ansehen.
Cayman
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1 each

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63 €

Cay70210-10
CAS: 340267-​36-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI, SI = IC50 COX-1/IC50 COX-2) of >500,000.
MW: 367 D
Formula: C17H12F3NO3S
Purity: >98%
Cayman
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10 mg

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167 €

Cay70210-5
CAS: 340267-​36-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI, SI = IC50 COX-1/IC50 COX-2) of >500,000.
MW: 367 D
Formula: C17H12F3NO3S
Purity: >98%
Cayman
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5 mg

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94 €

Cay70210-50
CAS: 340267-​36-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
CAY10404 is one of the most selective inhibitors of COX-2 which has been reported to date, with a selectivity index (SI, SI = IC50 COX-1/IC50 COX-2) of >500,000.
MW: 367 D
Formula: C17H12F3NO3S
Purity: >98%
Cayman
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50 mg

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731 €

Cay70271-10
CAS: 282728-​47-​6
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Indomethacin derivative which shows enhanced selectivity for the COX-2 isoform. IC50 for indomethacin heptyl ester for the inhibition of human recombinant COX-2 is 0.04 µM.
MW: 456 D
Formula: C26H30ClNO4
Purity: >98%
Cayman
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10 mg

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176 €

Cay70271-5
CAS: 282728-​47-​6
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Indomethacin derivative which shows enhanced selectivity for the COX-2 isoform. IC50 for indomethacin heptyl ester for the inhibition of human recombinant COX-2 is 0.04 µM.
MW: 456 D
Formula: C26H30ClNO4
Purity: >98%
Cayman
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5 mg

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100 €

Cay70271-50
CAS: 282728-​47-​6
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Indomethacin derivative which shows enhanced selectivity for the COX-2 isoform. IC50 for indomethacin heptyl ester for the inhibition of human recombinant COX-2 is 0.04 µM.
MW: 456 D
Formula: C26H30ClNO4
Purity: >98%
Cayman
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50 mg

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771 €

Cay70272-10
CAS: 261766-​32-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.
MW: 461 D
Formula: C27H25ClN2O3
Purity: >98%
Cayman
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10 mg

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121 €

Cay70272-5
CAS: 261766-​32-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.
MW: 461 D
Formula: C27H25ClN2O3
Purity: >98%
Cayman
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5 mg

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68 €

Cay70272-50
CAS: 261766-​32-​9
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. N-2PIA inhibits human recombinant and ovine COX-2 with IC50 values of 0.06 and 0.125 µM, respectively.
MW: 461 D
Formula: C27H25ClN2O3
Purity: >98%
Cayman
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50 mg

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528 €

Cay70273-10
CAS: 282728-​65-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
The IC50 values of indomethacin N-octyl amide for the inhibition of ovine COX-1 and human recombinant COX-2 are 66 µM and 40 nM, respectively, making it 1,650 times more potent as an inhibitor of COX-2 than COX-1.
MW: 469 D
Formula: C27H33ClN2O3
Purity: >98%
Cayman
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10 mg

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176 €

Cay70273-5
CAS: 282728-​65-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
The IC50 values of indomethacin N-octyl amide for the inhibition of ovine COX-1 and human recombinant COX-2 are 66 µM and 40 nM, respectively, making it 1,650 times more potent as an inhibitor of COX-2 than COX-1.
MW: 469 D
Formula: C27H33ClN2O3
Purity: >98%
Cayman
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5 mg

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100 €

Cay70273-50
CAS: 282728-​65-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
The IC50 values of indomethacin N-octyl amide for the inhibition of ovine COX-1 and human recombinant COX-2 are 66 µM and 40 nM, respectively, making it 1,650 times more potent as an inhibitor of COX-2 than COX-1.
MW: 469 D
Formula: C27H33ClN2O3
Purity: >98%
Cayman
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50 mg

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771 €

Cay70274-10
CAS: 261766-​29-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. Selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.
MW: 433 D
Formula: C24H20ClN3O3
Purity: >98%
Cayman
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10 mg

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121 €

Cay70274-5
CAS: 261766-​29-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. Selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.
MW: 433 D
Formula: C24H20ClN3O3
Purity: >98%
Cayman
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5 mg

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68 €

Cay70274-50
CAS: 261766-​29-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. Selectively inhibits human recombinant COX-2 with an IC50 of 0.052 µM. It is about 1,300 times less potent as an inhibitor of ovine recombinant COX-1.
MW: 433 D
Formula: C24H20ClN3O3
Purity: >98%
Cayman
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50 mg

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528 €

Cay70278-10
CAS: 261766-​23-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. It inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1.
MW: 490 D
Formula: C27H24ClN3O4
Purity: >98%
Cayman
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10 mg

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121 €

Cay70278-5
CAS: 261766-​23-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. It inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1.
MW: 490 D
Formula: C27H24ClN3O4
Purity: >98%
Cayman
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5 mg

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68 €

Cay70278-50
CAS: 261766-​23-​8
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Potent and selective reversible inhibitor of COX-2. It inhibits human recombinant and ovine COX-2 with IC50 values of 0.12 and 0.625 µM, respectively. It is about 400 times less potent as an inhibitor of human recombinant COX-1.
MW: 490 D
Formula: C27H24ClN3O4
Purity: >98%
Cayman
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50 mg

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528 €

Cay70590-10
CAS: 123653-​11-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.
MW: 314 D
Formula: C13H18N2O5S
Purity: >98%
Cayman
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10 mg

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84 €

Cay70590-25
CAS: 123653-​11-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.
MW: 314 D
Formula: C13H18N2O5S
Purity: >98%
Cayman
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25 mg

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198 €

Cay70590-5
CAS: 123653-​11-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.
MW: 314 D
Formula: C13H18N2O5S
Purity: >98%
Cayman
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5 mg

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44 €

Cay70590-50
CAS: 123653-​11-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 µM, respectively. The IC50 values for ovine COX-1 and -2 are 220 and 0.15 µM, respectively.
MW: 314 D
Formula: C13H18N2O5S
Purity: >98%
Cayman
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50 mg

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353 €

Cay70635-10
CAS: 443919-​96-​8
COX-​2 inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
COX-2/5-LO inhibitors such as CAY10416 are apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy.
MW: 536 D
Formula: C29H29FN2O5S
Purity: >95%
Cayman
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10 mg

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418 €

Cay70635-5
CAS: 443919-​96-​8
COX-​2 inhibitor, 5-​LO inhibitor Erklärungen der Abkürzungen ansehen.
COX-2/5-LO inhibitors such as CAY10416 are apoptosis-inducing agents and are potentially useful in prostate cancer chemotherapy.
MW: 536 D
Formula: C29H29FN2O5S
Purity: >95%
Cayman
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5 mg

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235 €

Cay70640-25000
CAS: 51803-​78-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 µM for human recombinant COX-1 and -2 (at 20 µM arachidonic acid), respectively.
MW: 308 D
Formula: C13H12N2O5S
Purity: >99%
Cayman
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25 g

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208 €

Cay70640-5000
CAS: 51803-​78-​2
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Nimesulide is a selective inhibitor of COX-2. The IC50 values are 70 and 1.27 µM for human recombinant COX-1 and -2 (at 20 µM arachidonic acid), respectively.
MW: 308 D
Formula: C13H12N2O5S
Purity: >99%
Cayman
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5 g

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57 €

Cay70645-10
CAS: 88149-​94-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.
MW: 411 D
Formula: C17H12BrFO2S2
Purity: >96%
Cayman
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10 mg

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225 €

Cay70645-25
CAS: 88149-​94-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.
MW: 411 D
Formula: C17H12BrFO2S2
Purity: >96%
Cayman
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25 mg

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532 €

Cay70645-5
CAS: 88149-​94-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.
MW: 411 D
Formula: C17H12BrFO2S2
Purity: >96%
Cayman
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5 mg

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118 €

Cay70645-50
CAS: 88149-​94-​4
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
DuP-697 is a member of the diaryl heterocycle group of selective COX-2 inhibitors which includes MK-966 (rofecoxib), SC-58125, and celecoxib. DuP-697 is a potent and time-dependent inhibitor of COX-2.
MW: 411 D
Formula: C17H12BrFO2S2
Purity: >96%
Cayman
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50 mg

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947 €

Cay70650-50000
CAS: 4394-​00-​7
COX-​2 inhibitor Erklärungen der Abkürzungen ansehen.
Niflumic acid is a selective inhibitor of COX-2. The IC50 values are 16 and 0.1 µM for human recombinant COX-1 and -2, respectively. The Ki values are 2 and 0.02 µM for ovine COX-1 and -2, respectively.
MW: 282 D
Formula: C13H9F3N2O2
Purity: >99%
Cayman
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50 g

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160 €



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