3 products were found matching "Cay10007243-50"!

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5(S)-HETE MaxSpec(R) Standard
5(S)-HETE MaxSpec(R) Standard

Item number: Cay10007243-10

5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4. 5(S)-HETE...
Keywords: 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Application: Bioactive lipid assays
CAS 70608-72-9
MW: 320.5 D
222.00€ *
Review
Leukotriene B4 MaxSpec(R) Standard
Leukotriene B4 MaxSpec(R) Standard

Item number: Cay10007240-10

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
Keywords: LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
CAS 71160-24-2
MW: 336.5 D
267.00€ *
Review
(±)-Nutlin-3
(±)-Nutlin-3

Item number: Cay10004372-50

(±)-Nutlin-3 is a racemic mixture of the p53-Mdm2 protein-protein interaction inhibitor (-)-nutlin-3 (Cay-18585) and its less active enantiomer (+)-nutlin-3 (Cay-10009816). In vivo, (±)-nutlin-3 (200 mg/kg twice daily) reduces tumor volume in an SJSA-1 osteosarcoma mouse xenograft model.Formal Name:...
Keywords: rel-4-[[(4R,5S)-4,5-bis(4-chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-pi...
Application: Cell cycle arrest promotor
CAS 548472-68-0
MW: 581.5 D
From 50.00€ *
Review