10 products were found matching "AG-40T-0314"!

Protein function: Key element of the urea cycle converting L-arginine to urea and L-ornithine, which is further metabolized into metabolites proline and polyamides that drive collagen synthesis and bioenergetic pathways critical for cell proliferation, respectively, the urea cycle takes place primarily in the liver...

Full-length NAPRTase (Bacillus subtilis). Liquid. in 20mM TRIS-HCl, pH 7.8 containing 50mM sodium chloride. Nicotinate Phosphoribosyltransferase (NAPRTase) is involved in the biological processes of pyridine nucleotide biosynthesis and nicotinate nucleotide salvage and functions by catalyzing the conversion of...

Human full-length PARP-3 [ARTD3] is fused to a HA-tag and a His-tag. Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride and 50mM imidazole, 0.2% NP-40 and 10% glycerol. PARP-3 is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of...

Prefered cleavage sequence is PxxF. Full-length Zmp1 (Mycobacterium tuberculosis) is fused at the N-terminus to a His-tag. Liquid. In 10mM TRIS-HCl, pH 8.0. M13 endopeptidases are single-pass, transmembrane zinc-metallopeptidases responsible in human for the regulation of the biological activity of many hormones and...

(3 x 50µg). The extracellular domain of human TRAIL (amino acids 95-281) is fused at the N-terminus to a His-tag and a linker peptide. Induces apoptosis in a concentration range of 10-100ng/ml. Note: Does not require a cross-linking enhancer for its potent biological activity. ED50: 20ng/ml (BJAB cells). For cell...

Human full-length NMNAT3 (aa 1-252) is fused at the N-terminus to a His-tag. Liquid. In 50mM TRIS-HCl, pH 8.0, containing 300mM sodium chloride, 1mM DTT and 10% glycerol. Mitochondrial NMNAT isoform. Catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form of...

(3 x 20µg). The extracellular domain of mouse TRAIL (amino acids 99-291) is fused at the N-terminus to a His-tag and a linker peptide. The active multimeric conformation is stabilized by an inserted mutation allowing an additional CC-bridge. Induces apoptosis at concentrations of >10ng/ml as tested on human tumor...

Human VEGF 165 (165aa). Lyophilized. Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to...

Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Lyophilized. EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR...

Human FGF-2 (153aa). Lyophilized. FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.