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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| BPS-60402 | 2 vials (2 vials) | - | - |
3 - 15 business days* |
11,632.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Recombinant HEK293 cell line expressing human PDE1B (phosphodiesterase 1B, accession number... more
Product information "PDE1B-HEK293 Cell line"
Recombinant HEK293 cell line expressing human PDE1B (phosphodiesterase 1B, accession number NM_000924).
N-terminal His-tagged human PDE1B has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The function of PDE1B was characterized by a cell-based cGMP assay. In this assay system, cells co-express atrial natriuretic peptide (ANP) receptor A (a guanylate cyclase), cyclic nucleotide5gated cation channel CNGA2, and the photoprotein aequorin. Intracellular cGMP level is monitored via aequorin luminescence induced by Ca2+ influx through CNGA2, acting as the intracellular cGMP sensor.
N-terminal His-tagged human PDE1B has been stably expressed in HEK293 cell line and its expression was confirmed by Western blotting. The function of PDE1B was characterized by a cell-based cGMP assay. In this assay system, cells co-express atrial natriuretic peptide (ANP) receptor A (a guanylate cyclase), cyclic nucleotide5gated cation channel CNGA2, and the photoprotein aequorin. Intracellular cGMP level is monitored via aequorin luminescence induced by Ca2+ influx through CNGA2, acting as the intracellular cGMP sensor.
| Keywords: | PDES1B, Cam-PDE 1B, 63 kDa Cam-PDE, Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B, |
| Supplier: | BPS Bioscience |
| Supplier-Nr: | 60402 |
Properties
| Application: | cAMP monitoring, PDE1B signaling pathway activity, activator / inhibitor screening |
| Host: | human cells |
| Species reactivity: | human |
| Format: | Solution |
Database Information
| KEGG ID : | K13755 | Matching products |
| UniProt ID : | Q01064 | Matching products |
| Gene ID | GeneID 5153 | Matching products |
Handling & Safety
| Storage: | Liquid nitrogen (store in liquid nitrogen) |
| Shipping: | -80°C (International: -80°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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