2 products were found matching "Cay90220-1"!

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Item number: Cay90200-1

5,8,11-ETI is a nonselective inhibitor of lipoxygenases. It inhibits 12-LO in human platelets with an ID50 value of 24 µM. 5,8,11-ETI also inhibits A23187 and L-cysteine induced LTC4 biosynthesis in mouse mastocytoma cells with an ID50 value of 5 µM. At higher concentrations, 5,8,11-ETI also inhibits cyclooxygenases...

Keywords:	5,8,11-ETI, 5,8,11-eicosatriynoic acid
Application:	LO inhibitor
CAS	13488-22-7
MW:	300.4 D

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gamma-Linolenic Acid

Item number: Cay90220-100

gamma-Linolenic acid (GLA) is an omega-6 fatty acid which can be elongated to arachidonic acid for endogenous eicosanoid synthesis. It is a weak LTB4 receptor antagonist, inhibiting [3H]-LTB4 binding to porcine neutrophil membranes with a Ki of 1 µM. GLA produces 53% inhibition at a 1 mg/kg dose in an in vivo model...

Keywords:	GLA, 6Z,9Z,12Z-octadecatrienoic acid
Application:	LTB4 receptor antagonist
CAS	506-26-3
MW:	278.4 D

From 34.00€ *

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