107 products were found matching "A2275-86F"!

Anti-human APP770 was raised using a synthetic 15-aa peptide near the extracellular, KPI-region (301-316 aa) of human APP770 (1). Peptide was conjugated to KLH. Alzheimer's Disease (AD) is a neurodegenerative disorder characterized by progressive loss of memory and cognition in the elderly. One of the most important...

Amyloid-beta precursor protein (APP) is the source of the amyloid-beta (Ab) peptide found in neuritic plaques of Alzheimer's disease (AD) patients. APP is aglycosylated transmembrane protein with a long extracellular N-terminal domain, a short intracellular C-terminal domain, and an Abeta-segment of intermediate...

Amyloid-beta precursor protein (APP) is the source of the amyloid-beta (Ab) peptide found in neuritic plaques of Alzheimer's disease (AD) patients. APP is aglycosylated transmembrane protein with a long extracellular N-terminal domain, a short intracellular C-terminal domain, and an Abeta-segment of intermediate...

APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid...

APPBP1 binds to the beta-amyloid precursor protein, a cell surface protein with signal-transducing properties thought to play a role in the pathogenesis of Alzheimer's disease. In addition, this protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. APPB1 is required for...

Amyloid monomeric proteins can sometimes oligomerize into destructive amyloid fibrils. Amyloidogenic conformations of non-disease related proteins can be created by partial protein misfolding or denaturation. In disease state oligomerization, extensive amyloid oligomerization creates plaques in neural tissue that...

Applications: , Suitable for use in Immunofluorescence, ELISA and Western Blot Other applications not tested. Recommended Dilution: Immunofluorescence: 5-20ug/ml , ELISA: 0.05-0.5ug/ml , Western Blot: 0.1-1.0ug/ml , Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for...

The serum amyloid A (SAA) family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma, and constitutive SAAs (C-SAAs). Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported....

A naturally occurring neurotoxin produced by hoplonemertine sea worms competes with the natural neurotransmitter acetylcholine when binding to nicotinic receptor sites. , Solubility: Chloroform , Storage and Stability:, May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum...

Solubility: , Chloroform, Method for Determining Identity: Proton NMR Spectroscopic Analysis and Mass Spectrometric analysis, TLC Conditions: SiO2: Dichloromethane: Methanol: Ammonium Hydroxide, 8ml, 2ml: 5 drops, Visualized with UV, Single spot, Rf=0.5, Storage and Stability: May be stored at RT for short-term...

Amyloid A, Serum, Human (Serum, Amyloid A, SAA) BioAssay(TM) ELISA Kit is to be used for the in vitro quantitative determination human serum amyloid A (SAA) concentrations in serum, plasma, cell culture supernatant and other biological fluids. Amyloidosis includes a family of diseases which have in common the...

Amyloid Precursor Protein (APP) is an integral membrane protein with a large ectodomain, a transmembrane domain, and a short cytoplasmic tail. APP is proteolytically cleaved by b-secretase (BACE) to generate the APP N-terminal fragment (sbAPP) with Mr100kD and a C-terminal fragment (C99) with Mr12kD. The smaller...