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(-)-(alpha)-Kainic Acid (hydrate)
(-)-(alpha)-Kainic Acid (hydrate)

Item number: Cay78050-50

(-)-(alpha)-Kainic acid is a cyclic analog of L-glutamate originally isolated from D. simplex that has neuroexcitatory activities. It binds to the homomeric kainate receptors GluK1, GluK2, GluK3, GluK4, and GluK5 (Kis = 75.9, 12.7, 32.8, 4.7, and 15 nM, respectively). (-)-(alpha)-Kainic acid (5 mM) induces calcium...
Keywords: 2S-carboxy-4S-(1-methylethenyl)-3S-pyrrolidineacetic acid, monohydrate
Application: Central nervous system stimulant
CAS 58002-62-3
MW: 231.2 D
From 97.00€ *
Review
ACPT-II
ACPT-II

Item number: Cay78020-50

ACPT-II is a general competitive antagonist of metabotropic glutamate (mGlu) receptors. The KB values for mGlu1a, mGlu2, and mGlu4a receptors are 115, 88, and 77 µM, respectively. It binds to the large extracellular domain called a Venus flytrap module, where agonists bind. ACPT-II is a stereoisomer of the group III...
Keywords: 4-amino-1alpha,2alpha,4beta-cyclopentanetricarboxylic acid
Application: Competitive metabotropic glutamate (mGlu) receptor antagonist
CAS 195209-04-2
MW: 217.2 D
From 60.00€ *
Review