4 products were found matching "Cay15031"!

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Ziprasidone (hydrochloride hydrate)
Ziprasidone (hydrochloride hydrate)

Item number: Cay15031-10

Ziprasidone is an atypical antipsychotic. It is an agonist of the serotonin (5-HT) receptor subtype 5-HT1A (EC50 = 36.31 nM for inhibition of forskolin-induced adenylate cyclase activity in HeLa cells expressing human receptors), as well as an inverse agonist of 5-HT1D receptors (IC50 = 2.69 nM) and a partial...
Keywords: CP-88,059, 5-[2-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]ethyl]-6-chloro-1,3-dihydro-2H-indol-2-one, monohydrochloride,...
Application: Serotonin 5-HT2A and dopamine D2 antagonist, 5-HT1A receptor agonist
CAS 138982-67-9
MW: 467.4 D
From 60.00€ *
Review
JC-1
JC-1

Item number: Cay15003-1

JC-1 is a membrane-permeable cationic dye that is used to study mitochondrial integrity in the context of cellular apoptosis. It selectively enters mitochondria and changes fluorescence characteristics with alteration in mitochondrial transmembrane potential (DeltaPsim). In healthy cells with a high mitochondrial...
Keywords: CBIC2, NK 1420,...
Application: Apoptosis studies, Mitochondrial membrane potential indicator
CAS 3520-43-2
MW: 652.2 D
From 92.00€ *
Review
JSH-23
JSH-23

Item number: Cay15036-1

JSH-23 is an inhibitor of NF-kappaB, blocking its translocation into the nucleus (IC50 = 7.1 µM). It does not affect degradation of the inhibitor of NF-kappaB, IkappaB. JSH-23 interferes with NF-kappaB-mediated gene expression and apoptosis in RAW 264.7 cells treated with lipopolysaccharide. It has also been used to...
Keywords: NF-kappaB Activation Inhibitor II, 4-methyl-N1-(3-phenylpropyl)-1,2-benzenediamine
Application: NFkappaB inhibitor
CAS 749886-87-1
MW: 240.3 D
From 66.00€ *
Review
Thymoquinone
Thymoquinone

Item number: Cay15039-1

The black seeds of Nigella have long been ingested to treat a broad range of diseases, including inflammation and cancer. Thymoquinone is a natural phytochemical isolated from the seeds of N. sativa. It has anti-inflammatory effects, blocking the synthesis of leukotrienes. Thymoquinone inhibits the growth of...
Keywords: NSC 2228, 2-methyl-5-(1-methylethyl)-2,5-cyclohexadiene-1,4-dione
Application: Apoptosis inducer
CAS 490-91-5
MW: 164.2 D
From 43.00€ *
Review