3 products were found matching "Cay14483"!
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Zinc Protoporphyrin-9
Item number: Cay14483-100
Zinc protoporphyrin-9 (ZnPPIX) is an endogenous metabolite formed during heme biosynthesis under conditions of iron insufficiency or impaired iron utilization. It also regulates heme catabolism through competitive inhibition of heme oxygenase, the rate-limiting enzyme in the heme degradation pathway that produces...
| Keywords: | ZnPPIX,... |
| Application: | Heme oxygenase inhibitor |
| CAS | 15442-64-5 |
| MW: | 626 D |
From 46.00€
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AG-1024
Item number: Cay14833-5
The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) initiates a cascade of reactions that promote cell growth and transformation by activating the PI3K/Akt signaling pathway, inhibiting apoptotic pathways, and mediating mitogenic actions. Overexpression of IGF-1R confers tumorigenic...
| Keywords: | AGS 200, Tyrphostin AG-1024, 2-[[3-bromo-5-(1,1-dimethylethyl)-4-hydroxyphenyl]methylene]-propanedinitrile |
| Application: | IGF-1R inhibitor |
| CAS | 65678-07-1 |
| MW: | 305.2 D |
From 66.00€
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GNF-5837
Item number: Cay14883-10
Tropomyosin-related kinases (Trks) are receptor tyrosine kinases activated by peptides, including neurotrophins. They have prominent roles in the development of central and peripheral nervous systems, vascular cell survival, and cancer. Rearrangement of genes for Trks with the transcription factor Tel, producing...
| Keywords: | N-[3-[[2,3-dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)... |
| Application: | Trk inhibitor |
| CAS | 1033769-28-6 |
| MW: | 535.5 D |
From 77.00€
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