- Search results for Cay10010421
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5 products were found matching "Cay10010421"!
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Item number: Cay10010421-10
The cyclic nucleotide second messenger guanosine 3'5'-cyclic monophosphate (cGMP) is an important mediator of signal transduction and hence a wide range of cellular processes. It can be generated by soluble guanylyl cyclase in response to binding of nitric oxide and degraded via members of the phosphodiesterase...
Keywords: | 2-(o-Propoxyphenyl)-8-azapurin-6-one, M&B 22,948, 3,6-dihydro-5-(2-propoxyphenyl)-7H-1,2,3-triazolo[4,5-d]pyrimidin-7-one |
Application: | PDE inhibitor |
CAS | 37762-06-4 |
MW: | 271.3 D |
From 38.00€
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Item number: Cay10010426-1
KRP 203 is a sphingosine-1-phosphate receptor 1 (S1P1) agonist. It selectively induces calcium mobilization in CHO-K1 cells expressing mouse S1P1 over mouse S1P3 and S1P4 (EC50s = 0.84, >1,000, and 9.61 nM, respectively). In vivo, KRP 203 (0.3 mg/kg) prevents the development of wasting syndrome, decreases diarrhea...
Keywords: | Mocravimod (hydrochloride), 2-amino-2-[2-[2-chloro-4-[[3-(phenylmethoxy)phenyl]thio]phenyl]ethyl]-1,3-propanediol,... |
Application: | S1P1 receptor agonist |
CAS | 509088-69-1 |
MW: | 480.4 D |
From 68.00€
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Item number: Cay10010425-1
Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-gamma-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto...
Keywords: | 13,14-dihydro-15-keto PGD1, 9alpha-hydroxy-11,15-dioxo-prost-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 1392219-79-2 |
MW: | 354.5 D |
From 169.00€
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Item number: Cay10010742-1
Prostaglandin F2alpha (PGF2alpha), acting through the FP receptor, causes smooth muscle contraction and exhibits potent luteolytic activity. Both 17-phenyl trinor PGF2alpha and 16-phenoxy tetranor PGF2alpha are metabolically stable analogs of PGF2alpha and potent agonists for the FP receptor. 17-phenoxy trinor...
Keywords: | 17-phenoxy trinor PGF2alpha ethyl amide,... |
Application: | Bioactive Lipid Assays |
CAS | 1421369-12-1 |
MW: | 431.6 D |
From 117.00€
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Item number: Cay10010412-1
Prostacyclin (PGI2) is a potent vasorelaxant and inhibitor of platelet aggregation. It mediates its actions by binding to a specific G protein-coupled receptor, the IP receptor, on the surface of endothelial cells, arterial smooth muscle, and platelets. The IP receptor also participates in signal transduction of the...
Keywords: | [4-[(5,6-diphenylpyrazinyl)(1-methylethyl)amino]butoxy]-acetic acid |
Application: | IP receptor agonist |
CAS | 475085-57-5 |
MW: | 419.5 D |
From 48.00€
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