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Zafirlukast
Zafirlukast

Item number: Cay10008282-10

Zafirlukast is a cysteinyl leukotriene 1 (CysLT1) receptor antagonist (IC50 = 0.014 µM in a cell-based calcium mobilization assay). It is selective for CysLT1 over CysLT2 receptors (IC50 = 58 µM). It inhibits mucus secretion induced by leukotriene D4 (LTD4, Cay-20310) in isolated guinea pig trachea (IC50 = 0.6 µM)....
Keywords: [3-[[2-methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]-carbamic acid,...
Application: CysLT1 receptor antagonist
CAS 107753-78-6
MW: 575.7 D
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