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Item number: LKT-Z4900.1

ZM447439 inhibits aurora kinases A and B (AurA, AurB), preventing mitotic spindle formation and proper completion of mitosis. This compound exhibits anticancer activity, inducing hyperploidy and apoptosis in osteosarcoma cells and inhibiting growth in mesothelioma cells. ZM447439 also induces apoptosis and inhibits...

Application:	Aurora A / B kinase inhibitor
CAS	331771-20-1
MW:	567.63 D

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