- Search results for Cay13601
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6 products were found matching "Cay13601"!
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Item number: Cay13601-10
The Aurora kinases have important roles in regulating mitosis and cytokinesis, with Aurora B involved in centromere function as part of the Chromosomal Passenger Complex, with survivin, INCENP, and borealin. ZM 447439 is a selective inhibitor of Aurora B kinase (IC50 = 50 nM), less potently inhibiting Aurora C and A...
Keywords: | N-[4-[[6-methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]-benzamide |
Application: | Aurora B kinase inhibitor |
CAS | 331771-20-1 |
MW: | 513.6 D |
From 82.00€
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Item number: Cay13360-1
Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 µg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2alpha.Formal Name:...
Keywords: | 8-epi PGE1, 8-iso PGE1, Ovinonic acid, 9-oxo-11alpha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 21003-46-3 |
MW: | 354.5 D |
From 69.00€
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Item number: Cay13602-1
MLN8237 is an inhibitor of Aurora A kinase (IC50 = 1 nM). It is selective for Aurora A over Aurora B kinase (IC50 = 396.5 nM). MLN8237 (50 nM) induces cell cycle arrest at the G2/M phase and chromosomal misalignment in HCT116 colon cancer cells. It inhibits tumor growth in a Calu-6 non-small cell lung cancer (NSCLC)...
Keywords: | Alisertib, 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxy benzoic acid |
Application: | Aurora A kinase inhibitor |
CAS | 1028486-01-2 |
MW: | 518.9 D |
From 43.00€
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Item number: Cay13608-1
(+)-CP 55,940 (Cay-13608) is an analytical reference standard that is structurally similar to known synthetic cannabinoids. This product is intended for research and forensic applications.Formal Name: 2-((1S,2S,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol. Molecular Formula: C24H40O3....
Keywords: | 2-((1S,2S,5S)-5-hydroxy-2-(3-hydroxypropyl)cyclohexyl)-5-(2-methyloctan-2-yl)phenol |
Application: | Analytical reference standard, bicyclic Delta9-THC mimetic |
MW: | 376.6 D |
From 339.00€
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Item number: Cay13680-1
15-keto PGE1 is the inactive metabolite of PGE1 produced by 15-hydroxy PGDH. It has greatly diminished biological activity compared to PGE1.Formal Name: (11alpha,13E)-11-hydroxy-9,15-dioxo-prost-13-en-1-oic acid. CAS Number: 22973-19-9. Synonyms: 15-keto PGE1. Molecular Formula: C20H32O5. Formula Weight: 352.5....
Keywords: | 15-keto PGE1, 9,15-dioxo-11alpha-hydroxy-prost-13E-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 22973-19-9 |
MW: | 352.5 D |
From 88.00€
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Item number: Cay13607-1
PMX-205 is a cyclic hexapeptide that acts as a potent antagonist of C5a receptor (C5aR, IC50 = 31 nM). It is orally active and blocks inflammatory signaling and symptoms in animal models of colitis and allergic asthma. PMX-205 is also brain penetrant and reduces neuroinflammation and neurodegeneration in an animal...
Keywords: | N2-(1-oxo-3-phenylpropyl)-L-ornithyl-L-prolyl-3-cyclohexyl-D-alanyl-L-tryptophyl-L-arginine, (5->1)-lactam,... |
Application: | C5a receptor antagonist |
MW: | 839.1 D |
From 261.00€
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