- Search results for Cay13271
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5 products were found matching "Cay13271"!
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Item number: Cay13271-5
ZLJ-6 is a dual inhibitor of COX and 5-lipoxygenase (5-LO) (IC50 = 0.73, 0.31, and 0.99 µM for COX-1, COX-2, and 5-LO, respectively, in whole blood). It reduces carrageenin-induced paw edema (inflammation) in rats and acetic acid-induced abdominal constriction (pain) in mice without causing gastrointestinal ulcers,...
Keywords: | (5Z)-2-amino-1,5-dihydro-1-methyl-5-[[4-(methylsulfonyl)phenyl]methylene]-4H-imidazol-4-one, monomethanesulfonate |
Application: | COX inhibitor, 5-LO inhibitor |
CAS | 1051931-39-5 |
MW: | 375.4 D |
From 53.00€
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Item number: Cay13227-1
Fumonisin B2 (FB2) is a mycotoxin that has been found in F. moniliforme. It is cytotoxic against a panel of seven rat hepatoma cell lines (IC50s = 3-50 µg/ml), as well as MDCK cells (IC50 = 2 µg/ml). FB2 (125-1,000 µM) is also cytotoxic to primary rat hepatocytes and induces hepatocyte nodule formation, a marker of...
Keywords: | FB2,... |
Application: | Apoptosis inducer |
CAS | 116355-84-1 |
MW: | 705.8 D |
From 163.00€
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Item number: Cay11327-1
The cytochalasins are cell-permeable fungal metabolites which inhibit actin polymerization. This interferes with such diverse processes as cell movement, growth, phagocytosis, degranulation, and secretion. Cytochalasin A is an oxidized analog of cytochalasin B that uniquely inhibits HIV-1 protease (IC50 = 3 µM)....
Keywords: | Dehydrophomin, NSC 174119, Phomin,... |
Application: | Actin polymerisation inhibitor |
CAS | 14110-64-6 |
MW: | 477.6 D |
From 68.00€
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Item number: Cay13327-1
PPM-18 is a naphthoquinone compound that inhibits NF-kappaB activation in vitro and in vivo (IC50 = 5 µM). Through this action, it inhibits the expression of inducible nitric oxide synthase (iNOS) in macrophages treated with lipopolysaccharide and suppresses inflammation and sepsis.Formal Name:...
Keywords: | NSC 73233, N-(1,4-dihydro-1,4-dioxo-2-naphthalenyl)-benzamide |
Application: | NF-kappaB inhibitor |
CAS | 65240-86-0 |
MW: | 277.3 D |
From 26.00€
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Item number: Cay13279-1
Fatty acid amide hydrolase (FAAH) degrades N-acyl ethanolamines (NAEs), including the endocannabinoid arachidonoyl ethanolamide (AEA). PF-3845 is a potent, selective, and irreversible inhibitor of FAAH (Ki = 0.23 µM). It covalently binds FAAH on Ser241 at the catalytic site, resulting in prolonged elevation of AEA...
Keywords: | N-3-pyridinyl-4-[[3-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]methyl]-1-piperidinecarboxamide |
Application: | FAAH inhibitor |
CAS | 1196109-52-0 |
MW: | 456.5 D |
From 39.00€
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