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Item number: Cay15228-50

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated (HCN) channels contribute to native pacemaker currents in heart and neurons and modulate cardiac and neuronal excitability. Certain HCN channels also accentuate neuropathic pain. ZD 7288 is a potent blocker of HCN channels that inhibits HCN4 more...

Keywords:	ICI-D 7288, N-ethyl-1,6-dihydro-1,2-dimethyl-6-(methylimino)-N-phenyl-4-pyrimidinamine, monohydrochloride
Application:	HCN channel blocker
CAS	133059-99-1
MW:	292.8 D

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