Xanomeline (oxalate)

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Xanomeline (oxalate) is a potent agonist of muscarinic acetylcholine receptors (EC50 values are 0.3, 92.5, 5, 52, and 42 nM for M1, M2, M3, M4, and M5, respectively). It has antipsychotic-like activities in rats and Cebus monkeys. M1 selective agonists, like Xanomeline (oxalate), enhance memory function and has utility in treating Alzheimer's Disease.Formal Name: 3-[4-(hexyloxy)-1,2,5-thiadiazol-3-yl]-1,2,5,6-tetrahydro-1-methyl-pyridine, ethanedioate. CAS Number: 141064-23-5. Synonyms: Lumeron, LY246708, Memcor. Molecular Formula: C14H23N3OS . C2H2O4. Formula Weight: 371.5. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 1.6 mg/ml, DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml. lambdamax: 223, 296 nm. SMILES: CCCCCCOC1=NSN=C1C2=CCCN(C)C2.OC(C(O)=O)=O. InChi Code: InChI=1S/C14H23N3OS.C2H2O4/c1-3-4-5-6-10-18-14-13(15-19-16-14)12-8-7-9-17(2)11-12,3-1(4)2(5)6/h8H,3-7,9-11H2,1-2H3,(H,3,4)(H,5,6). InChi Key: ZJOUESNWCLASJP-UHFFFAOYSA-N.