3 products were found matching "Cay14599"!
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WAY-100635 (maleate)
Item number: Cay14599-5
WAY-100635 is a potent, silent antagonist of serotonin 5-HT1A receptors with an IC50 value of 2.2 nM (Ki = 0.8 nM) for inhibiting 5-HT1A receptors in rat hippocampal membranes. Because it displays 100-fold selectivity for 5-HT1A over other 5-HT subtypes, WAY-100635 is classically used to examine the distribution and...
| Keywords: | N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-2-pyridinyl-cyclohexanecarboxamide, 2Z-butenedioate |
| Application: | 5-HT1A receptor antagonist |
| CAS | 1092679-51-0 |
| MW: | 538.6 D |
From 109.00€
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Ac-DEVD-AFC
Item number: Cay14459-1
During apoptosis, activated caspase-3 cleaves several substrates, including poly(ADP-ribose) polymerase, which it specifically targets at the amino sequence DEVD. Ac-DEVD-AFC is a fluorogenic substrate for activated caspase-3 (Km = 9.7 µM), as well as related caspases. Caspase activity can be quantified by...
| Keywords: | Caspase-3 Substrate (Fluorogenic), N-Acetyl-Asp-Glu-Val-Asp-7-amino-4-Trifluoromethylcoumarin,... |
| Application: | Caspase activity studies |
| CAS | 201608-14-2 |
| MW: | 729.6 D |
From 68.00€
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MDL 12330A (hydrochloride)
Item number: Cay14559-10
MDL 12330A is an adenylyl cyclase inhibitor that can also inhibit cAMP and cGMP phosphodiesterases and block slow extracellular and store-operated Ca2+ entry into cells. It is widely used to investigate the role of the adenylyl cyclase/cAMP signaling pathway. MDL 12330A has also been reported to block...
| Keywords: | RMI 12330A, rel-N-[(1R,2R)-2-phenylcyclopentyl]-azacyclotridec-1-en-2-amine, monohydrochloride |
| Application: | Adenylyl cyclase inhibitor, CAMP / cGMP phosphodiesterase inhibitor |
| CAS | 40297-09-4 |
| MW: | 377 D |
From 92.00€
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