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Anti-SMG1
Anti-SMG1

Item number: A301-535A-T

SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the...
Keywords: Anti-ATX, Anti-SMG1, Anti-SMG-1, Anti-hSMG-1, Anti-61E3.4, EC=2.7.11.1, Anti-Lambda-interacting protein,...
Application: WB
Host: Rabbit
Species reactivity: human
164.00€ *
Review
Anti-SMG1
Anti-SMG1

Item number: A301-535A

Protein function: Serine/threonine protein kinase involved in both mRNA surveillance and genotoxic stress response pathways. Recognizes the substrate consensus sequence [ST]-Q. Plays a central role in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by phosphorylating UPF1/RENT1. Recruited by...
Keywords: Anti-ATX, Anti-SMG1, Anti-SMG-1, Anti-hSMG-1, Anti-61E3.4, EC=2.7.11.1, Anti-Lambda-interacting protein,...
Application: WB, IP
Host: Rabbit
Species reactivity: human
588.00€ *
Review