13 products were found matching "Cay579000"!

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Sciadopitysin
Sciadopitysin

Item number: Cay27900-50

Sciadopitysin is a biflavonoid originally isolated from G. biloba and has diverse biological activities. It reduces cytotoxicity induced by amyloid-beta (1-42) (Abeta42, Cay-20574) in PC12 cells (EC50 = 9.84 µM). Sciadopitysin (0.1-10 µM) decreases methylglyoxal-induced insulin secretion, production of reactive...
Keywords: NSC 45108,...
Application: Bioactive biflavonoid
CAS 521-34-6
MW: 580.5 D
From 163.00€ *
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Palmitoyl Ethanolamide-d5
Palmitoyl Ethanolamide-d5

Item number: Cay9000573-100

Palmitoyl ethanolamide-d5 (PEA-d5) is intended for use as an internal standard for the quantification of PEA (Cay-90350) by GC- or LC-MS. PEA is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome...
Keywords: Palmidrol-d5, PEA-15,15,16,16,16-d5, N-(2-hydroxyethyl)-hexadecanamide-15,15,16,16,16-d5
Application: GC/LC-MS standard
MW: 304.5 D
From 68.00€ *
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Glatiramer (acetate)
Glatiramer (acetate)

Item number: Cay9000571-25

Glatiramer (acetate) is a mixture of synthetic polypeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery and induces the production of immunomodulatory molecules...
Keywords: Copolymer 1, L-glutamic acid, polymer with L-alanine, L-lysine, and L-tyrosine, monoacetate
Application: Immunomodulator, T-cell receptor antagonist
CAS 147245-92-9
MW: 2933 D
From 50.00€ *
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Lurasidone
Lurasidone

Item number: Cay9000570-5

Lurasidone is an atypical antipsychotic that binds to dopamine D2, serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT1A, and 5-HT7, and alpha2C-adrenergic receptors (Kis = 1.68, 2.03, 6.75, 0.495, and 10.8 nM, respectively). In vivo, pre-training administration of lurasidone (1 and 3 mg/kg) reverses impairment in...
Keywords: (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1...
Application: HTR1A / HTR2 / HTR7 / DRD2 modulator
CAS 367514-87-2
MW: 492.7 D
From 77.00€ *
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Fluorometholone
Fluorometholone

Item number: Cay9000157-50

Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM, Kd = 2.8 nM in a radioligand binding assay). Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment....
Keywords: NSC 33001, U-8614, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl-pregna-1,4-diene-3,20-dione
Application: Glucocorticoid receptor agonist
CAS 426-13-1
MW: 376.5 D
From 77.00€ *
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N6-(Delta2-Isopentenyl)adenine
N6-(Delta2-Isopentenyl)adenine

Item number: Cay17906-500

N6-(Delta2-Isopentenyl)adenine is a naturally occurring cytokinin that regulates cell division, development, and nutrient processing in plants. It serves as a precursor to zeatin synthesis.Formal Name: N-(3-methyl-2-buten-1-yl)-9H-purin-6-amine. CAS Number: 2365-40-4. Synonyms: Isopentenyladenine,...
Keywords: N6-(2-Isopentenyl)adenine, N6-Isopentenyladenine, Isopentenyladenine, NSC 106958, N-(3-methyl-2-buten-1-yl)-9H-purin-6-amine
Application: Cytokinin
CAS 2365-40-4
MW: 203.2 D
From 43.00€ *
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Myosmine
Myosmine

Item number: Cay17908-500

(±)-Nicotine (Cay-16535) is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (Kis = 481 and 11.1 nM for alpha3beta4 and alpha4beta2 subtypes, respectively) and possesses addictive and teratogenic properties. Myosmine is a minor...
Keywords: 3-(3,4-dihydro-2H-pyrrol-5-yl)-pyridine
Application: Tobacco alkaloid
CAS 532-12-7
MW: 146.2 D
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AZD 3229
AZD 3229

Item number: Cay27908-500

AZD 3229 is an inhibitor of c-Kit-driven cell proliferation. It selectively inhibits growth of c-Kit mutant (GI50s = 1-971 nM) and PDGFR mutant (GI50s = 1-22 nM) Ba/F3 cell lines over Ba/F3 cell lines expressing Tel-KDR/VEGFR2 (GI50 = 1,378 nM). AZD 3229 (20 mg/kg twice per day) induces tumor regression in a Ba/F3...
Keywords: N-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-1H-1,2,3-triazole-1-acetamide
Application: c-Kit-driven cell proliferation inhibitor
CAS 2248003-60-1
MW: 479.5 D
From 92.00€ *
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SEL120-34A
SEL120-34A

Item number: Cay27906-500

SEL120-34A is a dual inhibitor of cyclin-dependent kinase 8 (Cdk8) and Cdk19 (IC50s = 4.4 and 10.4 nM, respectively). It is selective for Cdk8 and Cdk19 over a panel of CDK/cyclin complexes at 1 µM. SEL120-34A (0.1-5 µM) inhibits IFN-gamma-induced phosphorylation of STAT1 in HCT116 colon cancer cells and the...
Keywords: 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)-4H-imidazo[4,5,1-ij]quinoline, hydrochloride
Application: Cdk8 / Cdk19 dual inhibitor
CAS 1609452-30-3
MW: 414.1 D
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5-methyl-2'-O-Methylcytidine
5-methyl-2'-O-Methylcytidine

Item number: Cay37908-500

5-methyl-2'-O-Methylcytidine is a modified nucleoside that has been found in S. solfataricus, T. neutrophilus, and P. occultum tRNA. It is found in Huh7 cells infected with Zika virus, hepatitis C virus (HCV), poliovirus, or HIV-1 provirus but not uninfected Huh7 cells. 5-methyl-2'-O-Methylcytidine (4 µg/ml)...
Keywords: 2'-O-Methyl-5-methyl-cytosine, m5Cm, 5-methyl-2'-O-methyl-cytidine
Application: Modified nucleoside
CAS 113886-70-7
MW: 271.3 D
From 96.00€ *
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NG 012
NG 012

Item number: Cay27509-500

NG 012 is a fungal metabolite originally isolated from P. verruculosum that has fungicidal and nerve growth factor-potentiating properties. It inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro. NG 012 (50 µM) increases the efficacy of the...
Keywords: BK223-A,...
Application: Fungicidal fungal metabolite, NGF potentiator
CAS 141731-76-2
MW: 662.6 D
From 82.00€ *
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Ribosomal Protein S6 (Total) TR-FRET Assay Kit
Ribosomal Protein S6 (Total) TR-FRET Assay Kit

Item number: Cay500279-480

This Ribosomal Protein S6 (Total) TR-FRET Assay Kit uses a homogeneous TR-FRET assay method amenable to rapid measurement of total protein levels in cells. This Ribosomal Protein S6 (Total) TR-FRET Assay Kit is suitable for screening a large number of samples. The signal is stable at room temperature for at least 24...
Keywords: Phosphoprotein NP33, 40S ribosomal protein S6, Small ribosomal subunit protein eS6
Application: TR-FRET
From 500.00€ *
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