- Search results for Cay579000
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13 products were found matching "Cay579000"!
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Item number: Cay27900-50
Sciadopitysin is a biflavonoid originally isolated from G. biloba and has diverse biological activities. It reduces cytotoxicity induced by amyloid-beta (1-42) (Abeta42, Cay-20574) in PC12 cells (EC50 = 9.84 µM). Sciadopitysin (0.1-10 µM) decreases methylglyoxal-induced insulin secretion, production of reactive...
Keywords: | NSC 45108,... |
Application: | Bioactive biflavonoid |
CAS | 521-34-6 |
MW: | 580.5 D |
From 163.00€
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Item number: Cay9000573-100
Palmitoyl ethanolamide-d5 (PEA-d5) is intended for use as an internal standard for the quantification of PEA (Cay-90350) by GC- or LC-MS. PEA is an endogenous fatty N-acyl ethanolamine and a derivative of the endocannabinoid arachidonoyl ethanolamide (AEA, Cay-90050). It selectively activates peroxisome...
Keywords: | Palmidrol-d5, PEA-15,15,16,16,16-d5, N-(2-hydroxyethyl)-hexadecanamide-15,15,16,16,16-d5 |
Application: | GC/LC-MS standard |
MW: | 304.5 D |
From 68.00€
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Item number: Cay9000571-25
Glatiramer (acetate) is a mixture of synthetic polypeptides composed of four amino acids found in myelin basic protein (MBP): L-Alanine, L-glutamic acid, L-lysine, and L-tyrosine. It prevents MBP from binding to MHC class II molecules in the periphery and induces the production of immunomodulatory molecules...
Keywords: | Copolymer 1, L-glutamic acid, polymer with L-alanine, L-lysine, and L-tyrosine, monoacetate |
Application: | Immunomodulator, T-cell receptor antagonist |
CAS | 147245-92-9 |
MW: | 2933 D |
From 50.00€
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Item number: Cay9000570-5
Lurasidone is an atypical antipsychotic that binds to dopamine D2, serotonin (5-HT) receptor subtypes 5-HT2A, 5-HT1A, and 5-HT7, and alpha2C-adrenergic receptors (Kis = 1.68, 2.03, 6.75, 0.495, and 10.8 nM, respectively). In vivo, pre-training administration of lurasidone (1 and 3 mg/kg) reverses impairment in...
Keywords: | (3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1... |
Application: | HTR1A / HTR2 / HTR7 / DRD2 modulator |
CAS | 367514-87-2 |
MW: | 492.7 D |
From 77.00€
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Item number: Cay9000157-50
Fluorometholone is a synthetic glucocorticoid that binds to glucocorticoid receptors (IC50 = 1.5 nM, Kd = 2.8 nM in a radioligand binding assay). Fluorometholone (0.01%) decreases survival of cultured corneal epithelial cells and inhibits their migration in a scratch assay following 12 hours of treatment....
Keywords: | NSC 33001, U-8614, 9-fluoro-11beta,17-dihydroxy-6alpha-methyl-pregna-1,4-diene-3,20-dione |
Application: | Glucocorticoid receptor agonist |
CAS | 426-13-1 |
MW: | 376.5 D |
From 77.00€
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Item number: Cay17906-500
N6-(Delta2-Isopentenyl)adenine is a naturally occurring cytokinin that regulates cell division, development, and nutrient processing in plants. It serves as a precursor to zeatin synthesis.Formal Name: N-(3-methyl-2-buten-1-yl)-9H-purin-6-amine. CAS Number: 2365-40-4. Synonyms: Isopentenyladenine,...
Keywords: | N6-(2-Isopentenyl)adenine, N6-Isopentenyladenine, Isopentenyladenine, NSC 106958, N-(3-methyl-2-buten-1-yl)-9H-purin-6-amine |
Application: | Cytokinin |
CAS | 2365-40-4 |
MW: | 203.2 D |
From 43.00€
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Item number: Cay17908-500
(±)-Nicotine (Cay-16535) is the racemic mixture of the dominant alkaloid found in tobacco plants. It acts as an agonist at neuronal nicotinic acetylcholine receptors (Kis = 481 and 11.1 nM for alpha3beta4 and alpha4beta2 subtypes, respectively) and possesses addictive and teratogenic properties. Myosmine is a minor...
Keywords: | 3-(3,4-dihydro-2H-pyrrol-5-yl)-pyridine |
Application: | Tobacco alkaloid |
CAS | 532-12-7 |
MW: | 146.2 D |
From 60.00€
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Item number: Cay27908-500
AZD 3229 is an inhibitor of c-Kit-driven cell proliferation. It selectively inhibits growth of c-Kit mutant (GI50s = 1-971 nM) and PDGFR mutant (GI50s = 1-22 nM) Ba/F3 cell lines over Ba/F3 cell lines expressing Tel-KDR/VEGFR2 (GI50 = 1,378 nM). AZD 3229 (20 mg/kg twice per day) induces tumor regression in a Ba/F3...
Keywords: | N-[4-[[5-fluoro-7-(2-methoxyethoxy)-4-quinazolinyl]amino]phenyl]-4-(1-methylethyl)-1H-1,2,3-triazole-1-acetamide |
Application: | c-Kit-driven cell proliferation inhibitor |
CAS | 2248003-60-1 |
MW: | 479.5 D |
From 92.00€
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Item number: Cay27906-500
SEL120-34A is a dual inhibitor of cyclin-dependent kinase 8 (Cdk8) and Cdk19 (IC50s = 4.4 and 10.4 nM, respectively). It is selective for Cdk8 and Cdk19 over a panel of CDK/cyclin complexes at 1 µM. SEL120-34A (0.1-5 µM) inhibits IFN-gamma-induced phosphorylation of STAT1 in HCT116 colon cancer cells and the...
Keywords: | 7,8-dibromo-5,6-dihydro-9-methyl-2-(1-piperazinyl)-4H-imidazo[4,5,1-ij]quinoline, hydrochloride |
Application: | Cdk8 / Cdk19 dual inhibitor |
CAS | 1609452-30-3 |
MW: | 414.1 D |
From 43.00€
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Item number: Cay37908-500
5-methyl-2'-O-Methylcytidine is a modified nucleoside that has been found in S. solfataricus, T. neutrophilus, and P. occultum tRNA. It is found in Huh7 cells infected with Zika virus, hepatitis C virus (HCV), poliovirus, or HIV-1 provirus but not uninfected Huh7 cells. 5-methyl-2'-O-Methylcytidine (4 µg/ml)...
Keywords: | 2'-O-Methyl-5-methyl-cytosine, m5Cm, 5-methyl-2'-O-methyl-cytidine |
Application: | Modified nucleoside |
CAS | 113886-70-7 |
MW: | 271.3 D |
From 96.00€
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Item number: Cay27509-500
NG 012 is a fungal metabolite originally isolated from P. verruculosum that has fungicidal and nerve growth factor-potentiating properties. It inhibits the growth of the plant pathogenic fungi B. cinerea, P. teres, P. lingam, S. sclerotiorum, and M. fructigena in vitro. NG 012 (50 µM) increases the efficacy of the...
Keywords: | BK223-A,... |
Application: | Fungicidal fungal metabolite, NGF potentiator |
CAS | 141731-76-2 |
MW: | 662.6 D |
From 82.00€
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Item number: Cay500279-480
This Ribosomal Protein S6 (Total) TR-FRET Assay Kit uses a homogeneous TR-FRET assay method amenable to rapid measurement of total protein levels in cells. This Ribosomal Protein S6 (Total) TR-FRET Assay Kit is suitable for screening a large number of samples. The signal is stable at room temperature for at least 24...
Keywords: | Phosphoprotein NP33, 40S ribosomal protein S6, Small ribosomal subunit protein eS6 |
Application: | TR-FRET |
From 500.00€
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