VU590 (hydrochloride)

VU590 (hydrochloride)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15177-5 5 mg -

6 - 10 business days*

104.00€
Cay15177-10 10 mg -

6 - 10 business days*

185.00€
Cay15177-25 25 mg -

6 - 10 business days*

436.00€
 
KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly... more
Product information "VU590 (hydrochloride)"
KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also causes 70% inhibition of KCNJ13 at 10 µM. It has no effect on the related channels KCNJ2 (Kir2.1) and KCNJ10 (Kir4.1) at a concentration of 10 µM.Formal Name: 7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane, dihydrochloride. CAS Number: 1783987-83-6. Synonyms: CID-4536383, ML-111. Molecular Formula: C24H32N4O7 . 2HCl. Formula Weight: 561.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMSO: 20 mg/ml, Water: 10 mg/ml. lambdamax: 259, 350 nm. SMILES: O=[N+](C(C=C1)=CC=C1CN2CCOCCOCCN(CCOCC2)CC3=CC=C([N+]([O-])=O)C=C3)[O-].Cl.Cl. InChi Code: InChI=1S/C24H32N4O7.2ClH/c29-27(30)23-5-1-21(2-6-23)19-25-9-13-33-14-10-26(12-16-35-18-17-34-15-11-25)20-22-3-7-24(8-4-22)28(31)32,,/h1-8H,9-20H2,2*1H. InChi Key: FRYYSUBAHIUBNJ-UHFFFAOYSA-N.
Keywords: CID-4536383, ML-111, 7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane, dihydrochloride
Supplier: Cayman Chemical
Supplier-Nr: 15177

Properties

Application: KCNJ1 inhibitor
MW: 561.5 D
Formula: C24H32N4O7 . 2HCl
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 1783987-83-6| Matching products
KEGG ID : K04995 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H302, H318
P Phrases: P264, P270, P280, P330, P301+P310, P305+P351+P338, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "VU590 (hydrochloride)"
Write a review
or to review a product.
Viewed