3 products were found matching "Cay15177"!
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VU590 (hydrochloride)
Item number: Cay15177-10
KCNJ1 (Kir1.1, or renal outer medullary potassium channel) and KCNJ13 (Kir7.1) are inwardly rectifying two-transmembrane K+ channels. KCNJ1 has critical roles in kidney function, while KCNJ13 is important in the eye, kidney, and small intestine. VU590 is a small molecule inhibitor of KCNJ1 (IC50 = 294 nM) which also...
| Keywords: | CID-4536383, ML-111, 7,13-bis(4-nitrobenzyl)-1,4,10-trioxa-7,13-diazacyclopentadecane, dihydrochloride |
| Application: | KCNJ1 inhibitor |
| CAS | 1783987-83-6 |
| MW: | 561.5 D |
From 104.00€
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2-Thenoyltrifluoroacetone
Item number: Cay15517-10
2-Thenoyltrifluoroacetone (TTFA) is an inhibitor of respiration in animals and bacteria. In animals, TTFA binds at the quinone reduction site of succinate:ubiquinone oxidoreductase (SQR, Complex II), preventing ubiquinone from binding. It inhibits NADH fumarate reductase in bacteria. TTFA also inhibits photosystem...
| Keywords: | NSC 405702, NSC 405703, NSC 405704, NSC 405705, NSC 405706, NSC 66544, TTFA, 4,4,4-trifluoro-1-(2-thienyl)-1,3-butanedione |
| Application: | Respiration inhibitor |
| CAS | 326-91-0 |
| MW: | 222.2 D |
From 50.00€
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Nevirapine
Item number: Cay15117-50
Nevirapine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). It binds to HIV-1 reverse transcriptase and inhibits RNA plus-strand initiation (IC50 = 0.45 µM). Nevirapine prevents seroconversion and viremia in a chimpanzee model of HIV-1 infection. Formulations containing nevirapine have been used in...
| Keywords: | BI-RG 587, NSC 641530, NVP, 11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one |
| Application: | Non-nucleoside reverse transcriptase inhibitor |
| CAS | 129618-40-2 |
| MW: | 266.3 D |
From 77.00€
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