2 products were found matching "Cay13132"!
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VER-50589
Item number: Cay13132-500
The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM. It produces a mean cellular antiproliferative GI50 value of 78 nM when tested against...
| Keywords: | 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-3-isoxazolecarboxamide |
| Application: | Hsp90 inhibitor |
| CAS | 747413-08-7 |
| MW: | 388.8 D |
From 66.00€
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(-)-Chaetominine
Item number: Cay13135-2.5
(-)-Chaetominine is a cytotoxic alkaloid originally isolated from Chaetomium sp. IFB-E015. It inhibits the growth of K562 leukemia and SW1116 colon cancer cells (IC50s = 20 and 28 nM, respectively). (-)-Chaetominine induces apoptosis of K562 cells via upregulation of the Bax/Bcl-2 ratio, decreasing mitochondrial...
| Keywords: | (2S,4R,5aS,9cS)-4,5,5a,9c-tetrahydro-5a-hydroxy-2-methyl-4-(4-oxo-3(4H)-quinazolinyl)-3H-2a,9b-diazacyclopenta[jk]fluorene... |
| Application: | Cytotoxic alkaloid |
| CAS | 918659-56-0 |
| MW: | 402.4 D |
From 191.00€
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