4 products were found matching "Cay13131"!

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VER-49009
VER-49009

Item number: Cay13131-1

The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. VER-49009 is a pyrazole compound that inhibits Hsp90 with an IC50 value of 47 nM. It produces a cellular antiproliferative GI50 value of 685 nM when tested against a...
Keywords: 3-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-5-carboxamide
Application: Hsp90 inhibitor
CAS 558640-51-0
MW: 387.8 D
From 135.00€ *
Review
N-acetyl-D-Glucosamine
N-acetyl-D-Glucosamine

Item number: Cay13136-1

N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc. Levels of O-GlcNAcylation proteins from Alzheimer's disease brain extracts are decreased as compared...
Keywords: GlcNAc, Marine Sweet, NAG, NSC 524344, 2-(acetylamino)-2-deoxy-D-glucose
Application: Alzheimer studies
CAS 7512-17-6
MW: 221.2 D
From 19.00€ *
Review
VER-50589
VER-50589

Item number: Cay13132-1

The heat shock proteins (Hsps) act as molecular chaperones. Hsp90 is an abundant protein with roles in protein folding, cell signaling, and cancer. VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM. It produces a mean cellular antiproliferative GI50 value of 78 nM when tested against...
Keywords: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-3-isoxazolecarboxamide
Application: Hsp90 inhibitor
CAS 747413-08-7
MW: 388.8 D
From 66.00€ *
Review
(-)-Blebbistatin
(-)-Blebbistatin

Item number: Cay13013-1

(-)-Blebbistatin is a selective cell-permeable inhibitor of non-muscle myosin II ATPases and the active enantiomer of (+)-blebbistatin (Cay-13165). It rapidly and reversibly inhibits Mg-ATPase activity and in vitro motility of non-muscle myosin IIA and IIB for several species (IC50s = 0.5-5 µM), while poorly...
Keywords: (S)-Blebbistatin, 1,2,3,3a-tetrahydro-3aS-hydroxy-6-methyl-1-phenyl-4H-Pyrrolo[2,3-b]quinolin-4-one
Application: Non-muscle myosin II ATPase inhibitor
CAS 856925-71-8
MW: 292.3 D
From 77.00€ *
Review