- Search results for Cay15742
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18 products were found matching "Cay15742"!
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Item number: Cay17542-5
c-Jun N-terminal kinases (JNKs) phosphorylate c-Jun and regulate transcription in response to an array of inflammatory signals. JNK inhibitor V is an ATP-competitive inhibitor of JNK1, JNK2, and JNK3 (IC50s = 150, 220, and 70 nM, respectively). While initial studies demonstrated 10- to 100-fold selectivity for JNK...
Keywords: | AS-601245, c-Jun N-terminal Kinase Inhibitor V, a-[2-[[2-(3-pyridinyl)ethyl]amino]-4-pyrimidinyl]-2-benzothiazoleacetonitrile |
Application: | JNK1 / JNK2 / JNK3 inhibitor |
CAS | 345987-15-7 |
MW: | 372.5 D |
From 76.00€
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Item number: Cay15427-50
Apixaban is an orally bioavailable, selective inhibitor of both free and prothrombinase-bound factor Xa (Kis = 0.8 nM). In vivo, apixaban has antithrombotic effects in a rabbit model of venous thrombosis. Apixaban (357.5 mg) also prevents thrombus formation without inducing adverse bleeding events in a porcine model...
Keywords: | BMS 562247-01,... |
Application: | Factor Xa inhibitor |
CAS | 503612-47-3 |
MW: | 459.5 D |
From 66.00€
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Item number: Cay14572-1
Citalopram is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with an IC50 value of 1.8 nM for 5-HT reuptake in rat brain synaptosomes. It is selective for 5-HT reuptake over that of dopamine and norepinephrine (IC50s = >6 mM). Citalopram potentiates headweaving and tremor induced by 5-hydroxy-L-tryptophan...
Keywords: | Bonitrile, Lu 10-171B, Nitalapram, Prepram,... |
Application: | Serotonin reuptake inhibitor, nicotinic acetylcholine receptor antagonist |
CAS | 59729-32-7 |
MW: | 405.3 D |
From 442.00€
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Item number: Cay15874-25
Dihydrotestosterone (Cay-15874) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including dihydrotestosterone, have been used to enhance physical performance in athletes. Dihydrotestosterone is regulated as a Schedule III compound in the United States. This...
Keywords: | Androstanolone, DHT, NSC 10972, Stanolone, (5alpha)-17beta-hydroxy-androstan-3-one |
Application: | Analytical reference standard, Anabolic androgenic steroid |
CAS | 521-18-6 |
MW: | 290.4 D |
From 369.00€
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Item number: Cay15784-25
Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two...
Keywords: | Signal Transducers and Activators of Transcription 5, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide... |
Application: | Cell permeable STAT5 inhibitor |
CAS | 285986-31-4 |
MW: | 293.3 D |
From 92.00€
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Item number: Cay15174-25
ML-097 is a small molecule pan activator of Ras-related GTPases, activating cell division cycle 42, Ras, and Rac1 with EC50 values of 102, 109, and 151 nM, respectively.Formal Name: 2-[(2-bromophenyl)methoxy]-benzoic acid. CAS Number: 743456-83-9. Synonyms: CID-2160985. Molecular Formula: C14H11BrO3. Formula Weight:...
Keywords: | CID-2160985, 2-[(2-bromophenyl)methoxy]-benzoic acid |
Application: | Ras-related GTPase activator |
CAS | 743456-83-9 |
MW: | 307.1 D |
From 60.00€
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Item number: Cay15374-25
Taurolidine is a synthetic taurine analog with antimicrobial and anti-neoplastic actions. It displays broad bactericidal and fungicidal activity. Taurolidine and its metabolites mimic mannose by binding to the extracellular wall of bacteria, blocking adherence to epithelial and fibroblast cells. In addition to...
Keywords: | 4,4'-methylenebis(tetrahydro-1,2H,4-thiadiazine) 1,1,1',1'-tetraoxide |
Application: | Antimicrobial mannose mimic |
CAS | 19388-87-5 |
MW: | 284.4 D |
From 43.00€
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Item number: Cay21574-1
alpha-Humulene is a sesquiterpene that has been found in C. sativa, C. indica, and hemp with diverse biological activities. It is lethal to A. subpictus, A. albopictus, and C. tritaeniorhynchus mosquito larvae (LC50s = 6.19, 7.39, and 12.05 mg/ml, respectively). alpha-Humulene reduces growth of MCF-7 breast cancer...
Keywords: | (±)-alpha-Humulene, alpha-Caryophyllene, 2,6,6,9-tetramethyl-1E,4E,8E-cycloundecatriene |
Application: | Bioactive sesquiterpene |
CAS | 6753-98-6 |
MW: | 204.4 D |
From 130.00€
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Item number: Cay15547-25
Hoechst 33342 is a cell-permeable, benzimidazole dye that stains DNA by binding to the minor groove of adenine and thymine-rich sequences. It emits blue fluorescence (excitation 350 nm/emission maximum 461 nm) when bound to double stranded DNA and is useful as a marker of nuclei for cell cycle studies and to...
Keywords: | Bisbenzimide, HOE 33342, NSC 334072, 2'-(4-ethoxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi-1H-benzimidazole,... |
Application: | Blue fluorescent DNA staining, FC, Fluorescence microscopy |
CAS | 875756-97-1 |
MW: | 561.9 D |
From 48.00€
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Item number: Cay15247-10
CID-16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 µM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 µM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2...
Keywords: | 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid |
Application: | GPR55 inverse agonist |
CAS | 834903-43-4 |
MW: | 425.4 D |
From 48.00€
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Item number: Cay15347-25
NS 11021 is an activator of large-conductance Ca2+-activated potassium channels (BKCa/KCa1.1). It is selective for BKCa and is thought to bind directly the alpha subunit. NS 11021 has been shown to relax intracavernous arterial rings and corpus cavernosum strips in vitro and to enhance erectile responses in intact...
Keywords: | N'-[3,5-bis(trifluoromethyl)phenyl]-N-[4-bromo-2-(2H-tetrazol-5-yl)phenyl]-thiourea |
Application: | KCNMA1 activator |
CAS | 956014-19-0 |
MW: | 511.2 D |
From 43.00€
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Item number: Cay15147-25
Corticotropin-releasing hormone (CRH) secreted from the hypothalamus is the major regulator of pituitary corticotropin-release and consequent glucocorticoid secretion. Antalarmin is a selective, nonpeptide antagonist of the CRH receptor 1 (Ki = 1 nM) that, consequently, reduces the release of corticotropin in...
Keywords: | N-butyl-N-ethyl-2,5,6-trimethyl-7-(2,4,6-trimethylphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine, monohydrochloride |
Application: | CRH receptor 1 antagonist |
CAS | 220953-69-5 |
MW: | 415 D |
From 147.00€
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