- Search results for AG-CN2-0085
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5 products were found matching "AG-CN2-0085"!
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Item number: AG-CN2-0085-M010
Isolated from Umbellularia californica Nutt. Offensive principle of the so-called "headache tree". Causes a painful cold sensation. Selective TRPA1 activator. Weak TRPM8 activator. Releases CGRP (calcitonin gene-related peptide) after TRPA1 activation which leads to activation of trigeminovascular pathways and...
Keywords: | (-)-Umbellulone, Umbellol, NSC 22046, BRN 2042730, Oreodaphnol, 3-Thujen-2-one |
Application: | Selective TRPA1 activator |
CAS | 546-78-1 |
MW: | 150,2 D |
From 165.00€
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Item number: AG-CN2-0089-M025
Isolated from Coleus forskohlii. Potent, cell permeable adenylyl cyclase activator. Increases intracellular cAMP levels. Widely used tool to investigate cAMP as a second messenger. Inotropic and antihypertensive. Smooth muscle relaxant/vasodilator. Glucose transporter inhibitor. Platelet aggregation inhibitor....
Keywords: | Boforsin, Colforsin, Coleonol, NSC 357088, NSC 375489 |
Application: | Cell permeable adenylate cyclase activator |
CAS | 66575-29-9 |
MW: | 410,5 D |
From 22.00€
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Item number: AG-CN2-0086-M005
Synthetic. Originally isolated from Euphorbia lagascae. Wide range of tyrosine and serine/threonine protein kinase inhibitor, including Syk, p56lck, PKA, PKC, MLCK, CDPK, JNK and PI3K. Inhibits the tyrosine phosphorylation of STAT3 and STAT5. Potent apoptosis inducer. Potent anticancer compound. Suppresses NF-kB...
Keywords: | CCRIS 9289, NSC365798, NSC622471, 3,3',4,5'-Tetrahydroxy-trans-stilbene, 3-Hydroxyresveratrol |
Application: | Tyrosine and serine/threonine protein kinase inhibitor |
CAS | 10083-24-6 |
MW: | 244,3 D |
From 33.00€
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Item number: AG-CN2-0084-M005
White to off-white solid. Soluble in DMSO or dimethyl formamide. Slightly soluble in methanol or water. Insoluble in ethanol. Chemical. CAS: 482-44-0. Formula: C16H14O4. MW: 270.3. Isolated from Opopanax chironium L. Anticancer compound. Apoptosis inducer. Induces DNA fragmentation at the G1/S phase of the cell...
Keywords: | Pentosalen, Marmelosin, Ammidin, NSC 402949, BAN |
Application: | Apoptosis inducer, Caspase-1 activity inhibitor |
CAS | 482-44-0 |
MW: | 270,3 D |
From 39.00€
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Item number: AG-CN2-0087-M005
Isolated from fungus Fusarium sp. Antiprotozoal. Potent inhibitor of histone deacetylase (HDAC). Inhibits proliferation. Induces cell cycle arrest at the G1 phase. Induces hyperacetylation of histone H4. Apoptosis inducer. Potent anti-angiogenic compound. Decreases HIF-1alpha protein levels and transcriptional...
Keywords: | cyclo-[L-(2-Amino-8-oxodecanoyl)-L-(N-methoxy-tryptophan)-L-isoleucyl-D-pipecolinyl], OSI-2040 |
Application: | Antiprotozoal, HDAC inhibitor |
CAS | 183506-66-3 |
MW: | 623,8 D |
From 72.00€
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