- Search results for Cay10774
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6 products were found matching "Cay10774"!
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Item number: Cay32569-1
CAY10774 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 (IC50 = 15 nM in a homologous time-resolved fret (HTRF) assay). It increases the activation of Jurkat cells expressing PD-1 in co-culture with artificial antigen-presenting cells (aAPCs) expressing...
Keywords: | (S)-1-(3-bromo-4-((2-bromo-[1,1'-biphenyl]-3-yl)methoxy)benzyl)piperidine-2-carboxylic acid |
Application: | PD-1/PD-L1 interaction inhibitor |
CAS | 2714327-65-6 |
MW: | 559.3 D |
From 43.00€
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Item number: Cay10774-25
Ubiquitously transcribed tetratricopeptide repeat X (UTX) gene codes for the widely-expressed UTX protein. The UTX gene is localized on the X chromosome and is a homolog of the ubiquitously transcribed mouse Y chromosome (UTY) gene. UTX gene expression has been shown to evade X-chromosome inactivation. The...
Keywords: | UTX, KDM6A, Histone demethylase UTX, Histone demethylase UTX, Lysine-specific demethylase 6A, Lysine-specific demethylase... |
Application: | Enzyme kinetics |
Expressed in: | E.coli |
MW: | 70,5 kD |
514.00€
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Item number: Cay29802-5
CAY10744 is a topoisomerase II-alpha poison. It inhibits topoisomerase II-alpha by 78.9% when used at a concentration of 20 µM. CAY10744 is selective for topoisomerase II-alpha over topoisomerase I providing 100 and 0% inhibition, respectively, at 100 µM. It inhibits proliferation of HCT15 colon, T47D breast, DU145...
Keywords: | 2-(2-chlorophenyl)-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-6-ol |
Application: | Topoisomerase II-alpha inhibitor |
CAS | 2375613-31-1 |
MW: | 385.8 D |
From 77.00€
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Item number: Cay10744-5
JWH 200 is an aminoalkylindole that acts as a cannabinoid (CB) receptor agonist, binding the CB1 receptor with high-affinity (IC50 = 7.8-42 nM). It is one of several synthetic CBs which have been included in smoking mixtures. JWH 200 4-hydroxyindole metabolite is expected to be a urinary metabolite of JWH 200 based...
Keywords: | 4-hydroxy[1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenyl-methanone |
Application: | Expected urinary JWH 200 metabolite |
CAS | 1427325-73-2 |
MW: | 400.5 D |
From 339.00€
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Item number: Cay11074-500
3-amino Benzamidoxime is a synthetic intermediate useful for pharmaceutical synthesis.Formal Name: 3-amino-N-hydroxy-benzenecarboximidamide. CAS Number: 100524-07-0. Molecular Formula: C7H9N3O. Formula Weight: 151.2. Purity: >97%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5...
Keywords: | 3-amino-N-hydroxy-benzenecarboximidamide |
Application: | Synthetic intermediate |
CAS | 100524-07-0 |
MW: | 151.2 D |
From 43.00€
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Item number: Cay10007444-1
Formulation: 120 µl of anti-PPARdelta antibody in TBS, pH 7.4, 50% glycerol and 1% BSA. Origin: Animal/Rabbit, Animal/Bovine.
Application: | Kit component |
Host: | Rabbit |
123.00€
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