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Bindarit
Bindarit

Item number: Cay11479-25

Bindarit is an inhibitor of monocyte chemoattractant protein (MCP) production that is selective for MCP-1/CCL2, MPC-3/CCL7, and MCP-2/CCL8 over other chemokines. It inhibits LPS- or C. albicans-induced production of MCP-1/CCL2 in isolated human monocytes (IC50s = 172 and 403 µM, respectively). Bindarit downregulates...
Keywords: AF 2838, 2-methyl-2-[[1-(phenylmethyl)-1H-indazol-3-yl]methoxy]-propanoic acid
Application: Monocyte chemotactic protein synthesis inhibitor
CAS 130641-38-2
MW: 324.4 D
From 32.00€ *
Review
ML-297
ML-297

Item number: Cay14792-5

G protein-regulated inwardly rectifying potassium (GIRK1-4) channels are a family of Kir3.1-Kir3.4 ion channels that modulate cell excitability. The four different GIRK subunits are composed in different homo- and heterotetrameric combinations, which are expressed with regional specificity throughout the central...
Keywords: CID-56642816, VU0456810, N-(3,4-difluorophenyl)-N'-(3-methyl-1-phenyl-1H-pyrazol-5-yl)-urea
Application: GIRK1/2 activator
CAS 1443246-62-5
MW: 328.3 D
From 66.00€ *
Review