- Search results for Cay14778-25
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11 products were found matching "Cay14778-25"!
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Item number: Cay14725-1
15(R)-15-methyl Prostaglandin E2 (15(R)-15-methyl PGE2) is a prodrug for the potent PGE2 (Cay-14010) analog 15(S)-15-methyl PGE2 (Cay-14730). Acid-catalyzed epimerization in the stomach produces the 15(S)-hydroxy compound which is biologically active. Oral administration of 15(R)-15-methyl PGE2 to dogs or rats at...
Keywords: | 15(R)-15-methyl PGE2, Arbaprostil, 9-oxo-11alpha,15R-dihydroxy-15-methyl-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 55028-70-1 |
MW: | 366.5 D |
From 115.00€
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Item number: Cay14775-100
Key Features Cayman's L3MBTL1 MBT Domains TR-FRET Assay Kit (Cay-601030) was developed using L3MBTL1 MBT domains (human recombinant, GST-tagged) protein.Bulk sizes available upon request "The malignant brain tumor (MBT) domain is structurally related to chromatin binding domains, such as chromodomains, tudor...
Keywords: | H-l(3)MBT, L(3)MBT-like, Lethal(3)Malignant Brain Tumor-like Protein 1 |
Application: | Binding assays |
Expressed in: | E.coli |
465.00€
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Item number: Cay14825-250
Fusidic acid is a fusidane antibiotic originally isolated from F. coccineum. It is active against the Gram-positive bacteria S. aureus, S. pyogenes, C. diphtheriae, B. subtilis, and C. tetani (MIC50s = 0.01-20 µg/ml) but not the Gram-negative bacteria E. coli, S. typhimurium, and P. vulgaris or the fungi C. albicans...
Keywords: | SQ 16,360, (4alpha,8alpha,9beta,13alpha,14beta)-16beta-(acetyloxy)-... |
Application: | Antibiotic |
CAS | 751-94-0 |
MW: | 538.7 D |
From 43.00€
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Item number: Cay14787-25
Dibutyl 3-hydroxybutyl phosphate (TBP-OH, Cay-9001825) is a compound produced from the metabolism of the organophosphorus solvent, tributyl phosphate (TBP). Incubation of goldfish liver microsomes in the presence of NADPH has been shown to convert TBP into TBP-OH and dibutyl phosphate. TBP-OH has also been produced...
Keywords: | (S)-TBP-OH, (S)-dibutyl (3-hydroxybutyl) phosphate |
Application: | Tributyl phosphate metabolite |
CAS | 2108602-99-7 |
MW: | 282.3 D |
From 84.00€
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Item number: Cay18477-25
ULK1 is a serine/threonine kinase that acts upstream of phosphatidylinositol 3-kinase (PI3K) to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. It is activated by phosphorylation by AMPK and, in turn, phosphorylates and inhibits AMPK. SBI-0206965 is...
Keywords: | 2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl-benzamide |
Application: | ULK1 inhibitor |
CAS | 1884220-36-3 |
MW: | 489.3 D |
From 98.00€
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Item number: Cay17847-25
Sulfinpyrazone is a uricosuric agent that competitively inhibits uric acid (Cay-16219) reabsorption in kidney proximal tubules, which is a key mechanism targeted in the treatment of gout. It can also inhibit degranulation of platelets, reducing the release of ADP and thromboxane and diminishing platelet...
Keywords: | G-28315, NSC 75925, 1,2-diphenyl-4-[2-(phenylsulfinyl)ethyl]-3,5-pyrazolidinedione |
Application: | Uricosuric |
CAS | 57-96-5 |
MW: | 404.5 D |
From 43.00€
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Item number: Cay14877-25
2,2,6,6-Tetramethylpiperidin-1-oxyl (TEMPO) is a stable radical that will react with reactive oxygen species (ROS). This conversion, followed by ESR, provides an indirect way to monitor ROS production in biological systems. TEMPONE is the 4-oxo derivative of TEMPO. In addition to possible uses as a spin trap, this...
Keywords: | 4-oxo-TEMPO, Triacetoneamine nitroxide, 2,2,6,6-tetramethyl-4-oxo-1-piperidinyloxy |
Application: | Spin trap, nitroxyl radical |
CAS | 2896-70-0 |
MW: | 170.2 D |
From 43.00€
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Item number: Cay14578-1
Ro 25-6981 (maleate) is a potent, selective activity-dependent blocker of NMDA receptors containing the NR2B subunit (IC50s = 9 nM and 52 µM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A, respectively). Ro 25-6981 (maleate) displays neuroprotectant effects in vitro, protecting cortical neurons...
Keywords: | alphaR-(4-hydroxyphenyl)-betaS-methyl-4-(phenylmethyl)-1-piperidinepropanol, 2Z-butenedioate |
Application: | NMDA receptor NR2B subunit antagonist |
CAS | 1312991-76-6 |
MW: | 455.6 D |
From 77.00€
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Item number: Cay18774-25
LY2409881 is a selective inhibitor of IkappaB kinase beta (IKK2, IC50 = 30 nM). It inhibits IKK1 and other common kinases at >10-fold higher concentrations. LY2409881 has been shown to suppress constitutively activated NF-kappaB and to induce apoptosis in lymphoma cells both in vitro and in preclinical mouse models...
Keywords: | 2-[5-chloro-2-[[3-(4-methyl-1-piperazinyl)propyl]amino]-4-pyrimidinyl]-N-cyclopropyl-benzo[b]thiophene-4-carboxamide,... |
Application: | IKK2 inhibitor |
CAS | 946518-60-1 |
MW: | 594.4 D |
From 43.00€
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Item number: Cay17478-5
The C2 domain of conventional PKC isoforms mediates calcium-dependent translocation. Peptides from that region can block PKC translocation and inhibit function, both in cells and cell lysates. PKCalpha (C2-4) inhibitor peptide is a synthetic peptide that blocks PKC activity in HepG2 cells stimulated with calcium and...
Keywords: | Protein Kinase Calpha (C2-4) Inhibitor Peptide |
Application: | PKC alpha inhibitor |
MW: | 1107.2 D |
From 129.00€
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Item number: Cay17278-5
Necrox-5 is a cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity. It predominantly localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 µM necrox-5 inhibits ~50% cell death in H9C2 cells...
Keywords: | Necrosis Inhibitor 5, NecroX-5,... |
Application: | Antioxidant |
CAS | 1383718-29-3 |
MW: | 645.8 D |
From 98.00€
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