- Search results for Cay10010245-50
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12 products were found matching "Cay10010245-50"!
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Item number: Cay10010240-5
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Olomoucine is a cdk inhibitor that acts by competing for the ATP binding site of the kinase. This purine derivative is an inhibitor for CDC2/cyclin B (IC50 = 7 µM), Cdk2/cyclin A (IC50...
Keywords: | 2-[[9-methyl-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-ethanol |
Application: | CDK inhibitor |
CAS | 101622-51-9 |
MW: | 298.3 D |
From 43.00€
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Item number: Cay10010540-50
1,2,3-Triheneicosanoyl glycerol is a triacylglycerol containing heneicosanoic acid (Cay-22593) groups at the sn-1, sn-2, and sn-3 positions. It has been used as an internal standard for the quantification of fatty acids in human breast milk samples and triacylglycerols in rat heart.Formal Name: heneicosanoic acid,...
Keywords: | Glycerol Triheneicosanoate, TG(21:0/21:0/21:0), Triheneicosanoin, heneicosanoic acid, 1,2,3-propanetriyl ester |
Application: | Fatty acid quantification internal standard |
CAS | 26536-14-1 |
MW: | 1017.7 D |
From 50.00€
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Item number: Cay10010250-1
Retinol is an essential micronutrient that plays a critical role in various physiological functions including cell growth and differentiation. Due to the instability and low solubility of retinol in the aqueous medium, it requires specific binding proteins in body fluids and within the cell for transport....
Keywords: | Cellular Retinol Acid-Binding Protein IV, cRBP7, RET7, Retinoid Binding Protein 7 |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human |
422.00€
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Item number: Cay10010241-50
AICAR is an activator of AMP-activated protein kinase (AMPK). It increases AMPK kinase activity in isolated hepatocytes (EC50 = ~500 µM) and reduces HMG-CoA reductase activity and fatty acid and sterol synthesis in these cells. AICAR (0.5 mM) inhibits insulin-stimulated glucose uptake to 62% of control cells and...
Keywords: | Acadesine, AICA-Riboside, NSC 105823, 5-amino-1-beta-D-ribofuranosyl-1H-imidazole-4-carboxamide |
Application: | AMPK activator |
CAS | 2627-69-2 |
MW: | 258.2 D |
From 64.00€
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Item number: Cay10010242-50
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of PTKs. Tyrphostins are a class of antiproliferative, compounds that act as PTK blockers. PTK inhibitors that preferentially inhibit the epidermal growth factor (EGF) receptor kinase block...
Keywords: | Tyrphostin AG-494, 2E-cyano-3-(3,4-dihydroxyphenyl)-N-phenyl-2-propenamide |
Application: | EGF receptor kinase inhibitor |
CAS | 133550-35-3 |
MW: | 280.3 D |
From 46.00€
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Item number: Cay10010248-50
Protein tyrosine kinase (PTK) inhibitors are potential antiproliferative agents for diseases caused by the hyperactivity of protein tyrosine kinases. Tyrphostins are a class of antiproliferative compounds which act as protein tryrosine kinase blockers. PTK inhibitors which preferentially inhibit the epidermal growth...
Keywords: | GCP 5126, Malonoben, NSC 242557, RG-50872, SF 6847, Tyrphostin 9, Tyrphostin AG-17,... |
Application: | EGF receptor kinase inhibitor |
CAS | 10537-47-0 |
MW: | 282.4 D |
From 38.00€
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Item number: Cay10010249-50
The H series isoquinolinesulfonamide protein kinase (PK) inhibitors are widely used to block signaling pathways to elucidate mechanisms of cellular regulation and signal transduction. H-8, an isoquinolinesulfonamide protein kinase (PK) inhibitor, is a potent inhibitor of PKA and PKG and shows moderate inhibition for...
Keywords: | Protein Kinase Inhibitor H-8, N-[2-(methylamino)ethyl]-5-isoquinolinesulfonamide, dihydrochloride |
Application: | PKA inhibitor, PKG inhibitor |
CAS | 113276-94-1 |
MW: | 338.3 D |
From 50.00€
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Item number: Cay10010275-50
Apigenin is a flavonoid compound found in many fruits and vegetables that selectively inhibits casein kinase 2 (CK2). Apigenin inhibits CK2 activity in the renal cortex with an IC50 value of 30 µM to improve renal function in a rat model of glomerulonephritis. CK2 inhibition by 20 µM apigenin decreases the...
Keywords: | Chamomile, Flavone, NSC 83244, Versulin, 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
Application: | CK2 inhibitor |
CAS | 520-36-5 |
MW: | 270.2 D |
From 82.00€
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Item number: Cay10010246-50
Glycogen synthase kinase 3 (GSK3) is a serine/threonine protein kinase that is inhibited by an assortment of extracellular stimuli including insulin, growth factors, cell specification factors, and cell adhesion. SB-216763 is a potent and selective cell permeable ATP-competitive inhibitor of GSK3alpha with an IC50...
Keywords: | 3-(2,4-dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione |
Application: | GSK inhibitor |
CAS | 280744-09-4 |
MW: | 371.2 D |
From 98.00€
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Item number: Cay10010265-50
LFM-A13 is an inhibitor of Bruton's tyrosine kinase (BTK, IC50 = 2.5 µM). It is selective for BTK over JAK1, JAK3, IRK, EGFR, and HCK (IC50s = >278 µM for all), as well as a panel of seven serine/threonine and 10 tyrosine kinases as well as one lipid kinase (IC50s = >200-500 µM), but does inhibit polo-like kinase 3...
Keywords: | 2Z-cyano-N-(2,5-dibromophenyl)3-hydroxy-2-butenamide |
Application: | Tyrosine kinase inhibitor |
CAS | 244240-24-2 |
MW: | 360 D |
From 92.00€
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Item number: Cay10010425-5
Prostaglandin D1 (PGD1) is the theoretical D-series metabolite of dihomo-gamma-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2. 13,14-dihydro-15-keto...
Keywords: | 13,14-dihydro-15-keto PGD1, 9alpha-hydroxy-11,15-dioxo-prost-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 1392219-79-2 |
MW: | 354.5 D |
From 169.00€
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Item number: Cay10010405-5
Bimatoprost is the Allergan trade name for 17-phenyl trinor prostaglandin F2alpha ethyl amide (17-phenyl trinor PGF2alpha ethyl amide), an F-series PG analog which has been approved for use as an ocular hypotensive drug. Oxidation of the C-15 hydroxyl group produces 15-keto-17-phenyl trinor PGF2alpha ethyl amide....
Keywords: | 15-keto-Bimatoprost, 17-phenyl trinor PGF2alpha ethyl amide,... |
Application: | F-series PG analog |
CAS | 1163135-96-3 |
MW: | 413.5 D |
From 92.00€
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