Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M)

Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
94964.10 10 µg - -

3 - 10 business days*

94.00€
94964.50 50 µg - -

3 - 10 business days*

208.00€
94964.1 1 mg - -

3 - 10 business days*

1,966.00€
 
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages... more
Product information "Tumor Necrosis Factor alpha Mutant/Variant, human recombinant (rHuTNF-a-M)"
Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. (www.uniprot.org) Produced in E.coli as a single, non-glycosylated polypeptide chain containing 151 amino acids. The mutant has an amino acid sequence deletion from amino acid 1-7, and the following amino acid substitutes Arg8, Lys9, Arg10 and Phe157 which is proven t
Keywords: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2
Supplier: Biomol GmbH
Supplier-Nr: 94964

Properties

Application: Cell culture
Conjugate: No
Host: E.coli
Species reactivity: human
MW: 16598.00 D
Format: Lyophilized

Database Information

KEGG ID : K03156 | Matching products
UniProt ID : P01375 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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