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Tumor Necrosis Factor Receptor Type 1, human recombinant...

Item number: 97323.5

Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific...

Keywords:	Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor...
Application:	Bioassay
Expressed in:	E.coli
Origin:	human
MW:	18200 D

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