Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR-CHO)

Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR-CHO)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
94971.10 10 µg - -

3 - 10 business days*

94.00€
94971.50 50 µg - -

3 - 10 business days*

208.00€
94971.1 1 mg - -

3 - 10 business days*

1,966.00€
 
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for... more
Product information "Tumor Necrosis Factor Receptor Fusion Protein, human recombinant (rHuTNFR-CHO)"
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity. (www.uniprot.org) Produced in CHO as a dimeric, glycosylated, polypeptide chain consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1.
Keywords: Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, p75, p80 TNF-alpha receptor, CD120b antigen, Etanercept, TBPII, TNFBR, TNFR80, TNF-R75, p75TNFR, TNF-R-II
Supplier: Biomol GmbH
Supplier-Nr: 94971

Properties

Application: Cell culture
Conjugate: No
Host: Hamster cells
Species reactivity: human
Purity: >98%
Format: Lyophilized

Database Information

KEGG ID : K05141 | Matching products
UniProt ID : P20333 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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