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PPQ-102
PPQ-102

Item number: Cay16275-5

The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR). PPQ-102 is a cell-permeable pyrimido-pyrrolo-quinoxalinedione that reversibly inhibits CFTR chloride channels with an IC50 value of 90 nM. At 0.5-5 µM, PPQ-102 has been used to reduce the size...
Keywords: CFTR Inhibitor IV, Cystic Fibrosis Transmembrane Conductance Regulator Inhibitor IV,...
Application: CFTR inhibitor
CAS 931706-15-9
MW: 438.5 D
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