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(S)-CR8
(S)-CR8

Item number: Cay29985-5

(S)-CR8 is a second generation derivative of (R)-roscovitine (Cay-10009569) and an inhibitor of cyclin-dependent kinase 1 (Cdk1/cyclin B), Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, and Cdk9/cyclin T (IC50s = 0.15, 0.08, 0.06, 0.12, and 0.11 µM, respectively). It also inhibits casein kinase CK1delta/epsilon...
Keywords: (2S)-2-[[9-(1-methylethyl)-6-[[[4-(2-pyridinyl)phenyl]methyl]amino]-9H-purin-2-yl]amino]-1-butanol
Application: Cyclin-dependent kinase inhibitor
CAS 1084893-56-0
MW: 431.5 D
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