Transforming Growth Factor-Beta 1, His Tag, human recombinant (rHuTGF-beta1-His)

Transforming Growth Factor-Beta 1, His Tag, human recombinant (rHuTGF-beta1-His)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97286.2 2 µg - -

3 - 10 business days*

94.00€
97286.10 10 µg - -

3 - 10 business days*

208.00€
97286.1 1 mg - -

3 - 10 business days*

6,989.00€
 
Multifunctional protein that controls proliferation, differentiation and other functions in many... more
Product information "Transforming Growth Factor-Beta 1, His Tag, human recombinant (rHuTGF-beta1-His)"
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts. (www.uniprot.org) Human recombinant TGF-b 1 produced in E.coli is a single, non-glycosylated, polypeptide chain containing 112 amino acids fragment (279-390) having a molecular weight of 17.3kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions that occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecule. TGF-b 1 regulates the actions of numerous other growth factors involved in a variety of human diseases including renal disease, hepatic disease, heart failure and cardiomyopathies.
Keywords: Transforming growth factor beta-1, TGF-beta-1, CED, DPD1, TGFB, TGF-b 1, TGFB1
Supplier: Biomol GmbH
Supplier-Nr: 97286

Properties

Application: Bioassay
Conjugate: No
Host: E.coli
Species reactivity: human
Purity: >95%
Format: Purified

Database Information

KEGG ID : K13375 | Matching products
UniProt ID : P01137 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Transforming Growth Factor-Beta 1, His Tag, human recombinant (rHuTGF-beta1-His)"
Write a review
or to review a product.
Viewed