Tiotropium (bromide)

Tiotropium (bromide)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay15773-1 1 mg -

6 - 10 business days*

98.00€
Cay15773-5 5 mg -

6 - 10 business days*

189.00€
Cay15773-25 25 mg -

6 - 10 business days*

578.00€
Cay15773-50 50 mg -

6 - 10 business days*

913.00€
 
Tiotropium is an antagonist that binds to M1, M2, and M3 muscarinic acetylcholine receptors (Kds... more
Product information "Tiotropium (bromide)"
Tiotropium is an antagonist that binds to M1, M2, and M3 muscarinic acetylcholine receptors (Kds = 0.43, 0.54, and 0.69 nM, respectively, for human receptors). It decreases acetylcholine-induced contraction of isolated guinea pig trachea in a concentration-dependent manner. In vivo, tiotropium (1 g/L inhaled aerosol) confers complete protection against acetylcholine-induced bronchospasms in anesthetized dogs. Formulations containing tiotropium have been used in the treatment of chronic obstructive pulmonary disease (COPD).Formal Name: (1alpha,2beta,4beta,5alpha,7beta)-7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, monobromide. CAS Number: 136310-93-5. Synonyms: BA 679BR. Molecular Formula: C19H22NO4S2 . Br. Formula Weight: 472.4. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 10 mg/ml, DMSO: 20 mg/ml, PBS (pH 7.2): 5 mg/ml. lambdamax: 238 nm. SMILES: O=C(C(C1=CC=CS1)(O)C2=CC=CS2)O[C@H]3C[C@H]4[C@H]5[C@H](O5)[C@H]([N+]4(C)C)C3.[Br-]. InChi Code: InChI=1S/C19H22NO4S2.BrH/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15,/h3-8,11-13,16-17,22H,9-10H2,1-2H3,1H/q+1,/p-1/t11-,12-,13+,16-,17+,. InChi Key: DQHNAVOVODVIMG-FOGIBKMMSA-M.
Keywords: BA 679BR, (1alpha,2beta,4beta,5alpha,7beta)-7-[(2-hydroxy-2,2-di-2-thienylacetyl)oxy]-9,9-dimethyl-3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane, monobromide
Supplier: Cayman Chemical
Supplier-Nr: 15773

Properties

Application: Muscarinic cholinergic receptor antagonist
MW: 472.4 D
Formula: C19H22NO4S2 . Br
Purity: >98%
Format: Crystalline Solid

Database Information

CAS : 136310-93-5| Matching products
KEGG ID : K04131 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: -20°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H302, H315, H319, H361, H373
P Phrases: P201, P202, P260, P264, P270, P280, P301+310, P302+352, P305+351+338, P308+313, P314, P321, P330, P332+313, P337+313, P362+364, P405, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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