- Search results for Cay16375
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9 products were found matching "Cay16375"!
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Item number: Cay16375-10
Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin (Cay-17161). While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. Tin(IV) protoporphyrin IX...
Keywords: | NSC 267099, SnPPIX,... |
Application: | HO-1 inhibitor |
CAS | 14325-05-4 |
MW: | 750.3 D |
From 66.00€
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Item number: Cay11637-5
Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel (Cay-10461). It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 µM and is cytotoxic to J774.2 cells (EC50 = 0.05 µM). In vivo, docetaxel inhibits tumor growth in several cancer models,...
Keywords: | NSC 628503, RP 56976, Taxotel, (alphaR,betaS)-beta-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic... |
Application: | Microtubule inhibitor |
CAS | 700367-34-6 |
MW: | 807.9 D |
From 54.00€
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Item number: Cay16337-5
SB-3CT is a selective, mechanism-based inhibitor of the gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9 (Kis = 28 and 400 nM, respectively). First pass metabolism of SB-3CT in vivo produces a monohydroxylated metabolite that has greater inhibitory activity (Kis = 6 and 160 nM for MMP-2 and MMP-9,...
Keywords: | Matrix Metalloproteinase-2/9 Inhibitor IV, MMP-2/MMP-9 Inhibitor IV, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane |
Application: | MMP-2 / MMP-9 inhibitor |
CAS | 292605-14-2 |
MW: | 306.4 D |
From 50.00€
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Item number: Cay16373-5
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution....
Keywords: | 4-SU, NSC 518132, 4-thio-uridine |
Application: | RNA-RNA crosslinking |
CAS | 13957-31-8 |
MW: | 260.3 D |
From 50.00€
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Item number: Cay16371-5
Soluble guanylate cyclase (sGC) is the primary cellular receptor for NO. NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cGMP. cGMP subsequently mediates a number of signaling cascades leading to vasorelaxation and inhibiting smooth muscle proliferation, leukocyte...
Keywords: | HMR 1766, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-benzamide |
Application: | sGC, oxidized, heme-free, form, activator |
CAS | 254877-67-3 |
MW: | 576.5 D |
From 109.00€
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Item number: Cay16370-5
8-iso Prostaglandin F2beta (8-iso PGF2beta) is an isomer of PGF2alpha with a non-enzymatic, non-cyclooxygenase origin. It is one of 64 possible isomers of PGF2alpha which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2beta exhibits very weak contraction of human umbilical vein artery and...
Keywords: | 8-epi PGF2beta, 8-iso PGF2beta, 8-iso-9beta-PGF2alpha, 9beta,11alpha,15S-trihydroxy-(8beta)-prosta-5Z,13E-dien-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 177020-26-7 |
MW: | 354.5 D |
From 98.00€
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Item number: Cay16374-25
alpha-Hydroxyglutaric acid (2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased levels of L-2-hydroxyglutaric acid (Cay-21123). 2-HG...
Keywords: | 2-HG, 2-Hydroxyglutaric Acid, 2-hydroxy-pentanedioic acid, disodium salt |
Application: | alpha-ketoglutarate-dependent dioxygenase inhibitor |
CAS | 40951-21-1 |
MW: | 192.1 D |
From 66.00€
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Item number: Cay16372-25
Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of alpha-lipoic acid (Cay-10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at...
Keywords: | DHLA, 6,8-dimercapto-octanoic acid |
Application: | Antioxidant |
CAS | 462-20-4 |
MW: | 208.3 D |
From 43.00€
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Item number: Cay16379-25
Chitobiose is a dimer of beta-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by...
Keywords: | Peracetylchitobiose,... |
Application: | Chitobiose oxazoline synthesis |
CAS | 41670-99-9 |
MW: | 676.6 D |
From 48.00€
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