9 products were found matching "Cay16375"!

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Tin Protoporphyrin IX (chloride)
Tin Protoporphyrin IX (chloride)

Item number: Cay16375-10

Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin (Cay-17161). While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. Tin(IV) protoporphyrin IX...
Keywords: NSC 267099, SnPPIX,...
Application: HO-1 inhibitor
CAS 14325-05-4
MW: 750.3 D
From 66.00€ *
Review
Docetaxel (hydrate)
Docetaxel (hydrate)

Item number: Cay11637-5

Docetaxel is a microtubule-stabilizing agent and a semisynthetic derivative of paclitaxel (Cay-10461). It promotes microtubule assembly in a cell-free assay when used at a concentration of 20 µM and is cytotoxic to J774.2 cells (EC50 = 0.05 µM). In vivo, docetaxel inhibits tumor growth in several cancer models,...
Keywords: NSC 628503, RP 56976, Taxotel, (alphaR,betaS)-beta-[[(1,1-dimethylethoxy)carbonyl]amino]-alpha-hydroxy-benzenepropanoic...
Application: Microtubule inhibitor
CAS 700367-34-6
MW: 807.9 D
From 54.00€ *
Review
SB-3CT
SB-3CT

Item number: Cay16337-5

SB-3CT is a selective, mechanism-based inhibitor of the gelatinases, matrix metalloproteinase-2 (MMP-2) and MMP-9 (Kis = 28 and 400 nM, respectively). First pass metabolism of SB-3CT in vivo produces a monohydroxylated metabolite that has greater inhibitory activity (Kis = 6 and 160 nM for MMP-2 and MMP-9,...
Keywords: Matrix Metalloproteinase-2/9 Inhibitor IV, MMP-2/MMP-9 Inhibitor IV, 2-[[(4-phenoxyphenyl)sulfonyl]methyl]-thiirane
Application: MMP-2 / MMP-9 inhibitor
CAS 292605-14-2
MW: 306.4 D
From 50.00€ *
Review
4-Thiouridine
4-Thiouridine

Item number: Cay16373-5

4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directly to the nucleotide base, thus 4-SU differs from uridine only by a single sulfur substitution....
Keywords: 4-SU, NSC 518132, 4-thio-uridine
Application: RNA-RNA crosslinking
CAS 13957-31-8
MW: 260.3 D
From 50.00€ *
Review
Ataciguat
Ataciguat

Item number: Cay16371-5

Soluble guanylate cyclase (sGC) is the primary cellular receptor for NO. NO binds and activates a heme group in sGC, initiating the conversion of GTP to the second messenger cGMP. cGMP subsequently mediates a number of signaling cascades leading to vasorelaxation and inhibiting smooth muscle proliferation, leukocyte...
Keywords: HMR 1766, 5-chloro-2-[[(5-chloro-2-thienyl)sulfonyl]amino]-N-[4-(4-morpholinylsulfonyl)phenyl]-benzamide
Application: sGC, oxidized, heme-free, form, activator
CAS 254877-67-3
MW: 576.5 D
From 109.00€ *
Review
8-iso Prostaglandin F2beta
8-iso Prostaglandin F2beta

Item number: Cay16370-5

8-iso Prostaglandin F2beta (8-iso PGF2beta) is an isomer of PGF2alpha with a non-enzymatic, non-cyclooxygenase origin. It is one of 64 possible isomers of PGF2alpha which can be produced by free radical peroxidation of arachidonic acid. 8-iso PGF2beta exhibits very weak contraction of human umbilical vein artery and...
Keywords: 8-epi PGF2beta, 8-iso PGF2beta, 8-iso-9beta-PGF2alpha, 9beta,11alpha,15S-trihydroxy-(8beta)-prosta-5Z,13E-dien-1-oic acid
Application: Bioactive lipid assays
CAS 177020-26-7
MW: 354.5 D
From 98.00€ *
Review
alpha-Hydroxyglutaric Acid (sodium salt)
alpha-Hydroxyglutaric Acid (sodium salt)

Item number: Cay16374-25

alpha-Hydroxyglutaric acid (2-HG) is an alpha-hydroxy acid. It is metabolized to 2-oxoglutarate by D- and L-2-hydroxyglutarate dehydrogenases, and mutations in these enzymes lead to 2-hydroxyglutaric aciduria, a neurometabolic disorder characterized by increased levels of L-2-hydroxyglutaric acid (Cay-21123). 2-HG...
Keywords: 2-HG, 2-Hydroxyglutaric Acid, 2-hydroxy-pentanedioic acid, disodium salt
Application: alpha-ketoglutarate-dependent dioxygenase inhibitor
CAS 40951-21-1
MW: 192.1 D
From 66.00€ *
Review
Dihydrolipoic Acid
Dihydrolipoic Acid

Item number: Cay16372-25

Dihydrolipoic acid (DHLA) is a dithiol-containing carboxylic acid that is the reduced form of alpha-lipoic acid (Cay-10005728). It acts as a general antioxidant that is highly reactive against a variety of reactive oxygen species, including hydroxyl radicals, peroxynitirite, hydrogen peroxide, and hypochlorite, at...
Keywords: DHLA, 6,8-dimercapto-octanoic acid
Application: Antioxidant
CAS 462-20-4
MW: 208.3 D
From 43.00€ *
Review
Chitobiose Octaacetate
Chitobiose Octaacetate

Item number: Cay16379-25

Chitobiose is a dimer of beta-1,4 linked glucosamine units derived from chitin, which, in turn, is a long chain polymer of N-acetylglucosamine that is a primary component of fungal cell walls and arthropod exoskeletons. Chitobiose octaacetate is a form of chitobiose containing eight acetate groups. It is formed by...
Keywords: Peracetylchitobiose,...
Application: Chitobiose oxazoline synthesis
CAS 41670-99-9
MW: 676.6 D
From 48.00€ *
Review