Tide Fluor(TM) 7 alkyne (TF7 alkyne)

Tide Fluor(TM)7 (TF7) family has the spectral properties similar to those of Cy7, IRDye 800 and Alexa Fluor 750. Their fluorescence is pH-independent from pH 3 to 11. These characteristics make this new dye family more robust to pH-sensitive assays. In some cases TF7-labeled peptides and nucleotides exhibit stronger fluorescence and higher photostability than the ones labeled with Cy7, IRDye 800 and Alexa Fluor 750. In pairing with our Tide Quencher(TM) 7 (TQ7), a variety of FRET peptides and nucleotides can be developed for detecting proteases and molecular beacons with enhanced sensitivity and stability. This TF7 product is reactive to azides, and useful for click chemistry.