Thymus and Activation Regulated Chemokine (CCL17), mouse recombinant (rmTARC)

Thymus and Activation Regulated Chemokine (CCL17), mouse recombinant (rmTARC)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
97570.5 5 µg - -

3 - 10 business days*

94.00€
97570.20 20 µg - -

3 - 10 business days*

208.00€
97570.1 1 mg - -

3 - 10 business days*

3,952.00€
 
Mouse recombinant TARC produced in E.coli is a non-glycosylated, polypeptide chain containing 70... more
Product information "Thymus and Activation Regulated Chemokine (CCL17), mouse recombinant (rmTARC)"
Mouse recombinant TARC produced in E.coli is a non-glycosylated, polypeptide chain containing 70 amino acids and having a molecular mass of 7.9kDa. TARC cDNA encodes a 94 amino acid precursor protein with a 23 amino acid residue signal peptide that is cleaved off to generate the 71 amino acid residue mature secreted protein. Along with CC chemokine family members, CCL-17 has approximately 24-29% amino acid sequence identity with RANTES, MIP-1alpha, MIP-1beta, MCP-1, MCP-2, MCP-3 and I-309. TARC is expressed in thymus, and at a lower level in the lung, colon, and small intestine. TARC is in addition transiently expressed in stimulated peripheral blood mononuclear cells. recombinant TARC has been shown to be chemotactic for T cell lines but not monocytes or neutrophils. CCL-17 was recently identified to be a specific functional ligand for CCR4, a receptor that is selectively expressed on T cells. CCL17 is one of quite a few Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. CCL17 shows chemotactic activity for T lymphocytes, but not monocytes or granulocytes. CCL17 binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells
Keywords: C-C motif chemokine 17, Small-inducible cytokine A17, Thymus and activation-regulated chemokine, CC chemokine TARC, ABCD-2, CCL17, CCL-17, SCYA17, TARC, A-152E5.3, MGC138271, MGC138273.
Supplier: Biomol GmbH
Supplier-Nr: 97570

Properties

Application: Cell Culture
Conjugate: No
Host: E.coli
Species reactivity: mouse
MW: 7900 D
Purity: >97%
Format: Lyophilized

Database Information

KEGG ID : K21083 | Matching products
UniProt ID : GeneID 20295 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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