Thrombin (human)

Thrombin (human)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay13188-250 250 U -

6 - 10 business days*

205.00€
Cay13188-1 1 kU -

6 - 10 business days*

611.00€
 
Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin... more
Product information "Thrombin (human)"
Thrombin is the last enzyme in the clotting cascade functioning to cleave fibrinogen to fibrin and potentiates the procoagulation process by activating factors V, VIII, XI, and XIII. Conversely, thrombin aids the anticoagulant process by activating protein C. Activated protein C inhibits activated factors V and VIII ultimately down-regulating further thrombin production. Thrombin is often used as a potent platelet activator in vitro. Platelet responses to thrombin are mediated through protease-activated receptors (PARs). Thrombin-mediated signaling regulates a diverse range of metabolic processes including activation of phospholipases in platelets, endothelial cells, and cardiac myocytes.Synonyms: Activated Factor II [IIa]. Source: Human blood, all source material tested and found non-reactive to HTLV-III and HBsAg using FDA approved assay methods. MW: 38 kDa. Formulation: (Request formulation change), 5 mM sodium citrate, pH 6.5, containing 0.01% PEG and 20 mM sodium chloride. Specific Activity: > 2,000 NIH units/mg.
Keywords: Activated Factor II [IIa]
Supplier: Cayman Chemical
Supplier-Nr: 13188

Properties

Application: Thrombin mediated signaling studies
Conjugate: No
MW: 38 kD
Format: Solution

Database Information

KEGG ID : K01313 | Matching products
UniProt ID : P00734 | Matching products

Handling & Safety

Storage: -80°C
Shipping: -80°C (International: -80°C)
Signal Word: Danger
GHS Hazard Pictograms:
H Phrases: H316, H334
P Phrases: P261, P284, P304+341, P332+313, P342+311
Caution
Our products are for laboratory research use only: Not for administration to humans!
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