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Item number: Cay10011127-1

Thioperamide (maleate) is a selective histamine H3 receptor antagonist that crosses the blood-brain barrier. This compound binds to rat cerebral cortical cells in vitro with a pKi value of 8.4 and inhibits histamine binding in vivo with an ED50 value of 1 mg/kg. At a dose of 5 mg/kg thioperamide (maleate) inhibits...

Keywords:	N-cyclohexyl-4-(1H-imidazol-5-yl)-1-piperidinecarbothioamide, 2Z-butenedioate
Application:	Histamine H3 receptor antagonist
CAS	148440-81-7
MW:	408.5 D

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