Thaxtomin A is a major phytotoxin produced by S. scabies, gram-positive soil bacterium responsible for producing scabs on tubers and root vegetables. This bacterial metabolite acts as a virulence factor in the common scab potato disease and demonstrates herbicidal activity against the dicotyledon weeds B. campestris...

Thiorphan is an inhibitor of neprilysin (NEP, IC50 = 0.007 µM). It selectivity inhibits NEP over NEP2 (IC50 = 22 µM), as well as angiotensin-converting enzyme (ACE) and endothelin-converting enzyme 1 (ECE1, Kis = >0.1 and >10 µM, respectively, in cell-free assays). Thiorphan (10 µM) increases bradykinin-induced...