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TTNPB is an analog of retinoic acid (Cay-11017) that potently and selectively activates retinoic... more
Product information "TTNPB"
TTNPB is an analog of retinoic acid (Cay-11017) that potently and selectively activates retinoic acid receptors (EC50s = 21, 4, and 2.4 nM for RARalpha, RARbeta, and RARgamma, respectively). It does not act on retinoid X receptors and weakly agonizes farnesoid X receptor (EC50 > 1 µM). TTNPB is used to study RAR action in diverse processes, including epidermal cell proliferation, embryogenesis, and stem cell differentiation.Formal Name: 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-benzoic acid. CAS Number: 71441-28-6. Synonyms: AGN 191183, Arotinoid Acid, Ro 13-7410. Molecular Formula: C24H28O2. Formula Weight: 348.5. Purity: >98%. Formulation: (Request formulation change), A crystalline solid. Solubility: DMF: 5 mg/ml, DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml, DMSO: 2 mg/ml, Ethanol: 0.1 mg/ml. lambdamax: 229, 303 nm. SMILES: CC1(C)C2=C(C=CC(/C(C)=C/C3=CC=C(C(O)=O)C=C3)=C2)C(C)(C)CC1. InChi Code: InChI=1S/C24H28O2/c1-16(14-17-6-8-18(9-7-17)22(25)26)19-10-11-20-21(15-19)24(4,5)13-12-23(20,2)3/h6-11,14-15H,12-13H2,1-5H3,(H,25,26)/b16-14+. InChi Key: FOIVPCKZDPCJJY-JQIJEIRASA-N.
Keywords: | AGN 191183, Arotinoid Acid, Ro 13-7410, 4-[(1E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propen-1-yl]-benzoic acid |
Supplier: | Cayman Chemical |
Supplier-Nr: | 16144 |
Properties
Application: | Retinoic acid receptor agonist |
MW: | 348.5 D |
Formula: | C24H28O2 |
Purity: | >98% |
Format: | Crystalline Solid |
Database Information
CAS : | 71441-28-6| Matching products |
KEGG ID : | K08529 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +20°C (International: -20°C) |
Signal Word: | Danger |
GHS Hazard Pictograms: |
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H Phrases: | H315, H319, H335, H360 |
P Phrases: | P201, P202, P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P308+313, P312, P321, P332+313, P337+313, P362+364, P403+233, P405, P501 |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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