Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two...

8-iso Prostaglandin F1alpha (8-iso PGF1alpha) is an isoprostane that was first identified in human semen. It is a member of the isoprostane family, which are eicosanoids of non-cyclooxygenase origin. 8-iso PGF1alpha is present along with its 19-hydroxy congener at 5-10 µg/ml of seminal plasma.Formal Name:...

Bicyclomycin benzoate is an antibiotic produced by S. sapporonensis that inhibits Gram-negative bacteria, including E. coli, Klebsiella, Shigella, Salmonella, Citrobacter, E. cloacae, and the pathogenic group of Neisseria. It is inactive against Proteus, P. aeruginosa, and Gram-positive bacteria.Formal Name:...

Prostaglandin E2 (PGE2) isopropyl ester is a more lipophilic form of the free acid, PGE2. PG esters have enhanced lipid solubility compared to their parent compounds. They are generally hydrolyzed to the free acid by endogenous esterases upon in vivo administration, making the esters useful prodrugs. In general, the...

Pyrrolidinophenones and butyrophenones are chemical compounds that feature ketone functional groups affixed to the narcotic cathinone. They bear a strong structural relationship with the stimulant alpha-pyrrolidinopentiophenone (alpha-PVP, Cay-9001083) and many have been identified as components of designer drugs....