- Search results for Cay15749
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10 products were found matching "Cay15749"!
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Item number: Cay14957-1
Adenosine 5'-(gamma-thio)-triphosphate (lithium salt) is a stable analog of ATP that acts as a potent agonist of G protein-coupled P2Y2 and P2Y11 receptors (pEC50 = 5.52 for P2Y11). It has been used to identify kinase substrates, has been implemented as a reagent in the synthesis of DNA N-acetylglucosamine analogs,...
Keywords: | ATPgammaS, P'-anhydride with phosphorothioic acid adenosine 5'-(trihydrogen diphosphate), tetralithium salt |
Application: | ATP analog, GPCR P2Y2 / P2Y11 agonist |
CAS | 93839-89-5 |
MW: | 547 D |
From 42.00€
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Item number: Cay15479-1
(+)-JQ1 (Cay-11187) binds to the acetyl-lysine recognition pocket of bromodomains 1 and 2 on BRD4 with Kd values of ~50 and 90 nM, respectively. This displaces BRD4 from nuclear chromatin in cells, inducing differentiation and growth arrest in midline carcinoma cells. CPI-203 is a primary amide analog of (+)-JQ1...
Keywords: | (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide |
Application: | BRD4 binding inhibitor |
CAS | 1446144-04-2 |
MW: | 399.9 D |
From 77.00€
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Item number: Cay14579-5
Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively. Purvalanol A reversibly arrests synchronized cells in the G1 and G2 phase of...
Keywords: | NG 60, (2R)-2-[[6-[(3-chlorophenyl)amino]-9-(1-methylethyl)-9H-purin-2-yl]amino]-3-methyl-1-butanol |
Application: | CDK inhibitor |
CAS | 212844-53-6 |
MW: | 388.9 D |
From 43.00€
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Item number: Cay15497-10
PV8 (hydrochloride) (Cay-14762) is an analog of the regulated psychoactive compound alpha-pyrrolidinopentiophenone (hydrochloride) (Cay-9001083). 4-methoxy PV8 is a para-methoxy analog of PV8. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and...
Keywords: | p-MeO-PV8, p-methoxy PHPP, p-methoxy PV8, para-MeO-PV8, para-methoxy PHPP, para-methoxy PV8, 4-MeO-PV8, 4-methoxy PHPP,... |
Application: | Analytical reference standard, Para-methoxy PV8 analog |
CAS | 2749302-60-9 |
MW: | 325.9 D |
From 280.00€
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Item number: Cay19574-5
Psicofuranine is an antibiotic and antitumor compound that acts as an inhibitor of xanthosine monophosphate (XMP) aminase (IC50 = 67 µM), causing guanine deficiency in enteric bacteria.Formal Name: 1'-C-(hydroxymethyl)-adenosine. CAS Number: 1874-54-0. Synonyms: Angustmycin C, NSC 53104. Molecular Formula:...
Keywords: | Angustmycin C, NSC 53104, 1'-C-(hydroxymethyl)-adenosine |
Application: | Xanthosine monophosphate (XMP) aminase inhibitor, Antibiotic |
CAS | 1874-54-0 |
MW: | 297.3 D |
From 142.00€
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Item number: Cay15947-10
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. OTX015 is an...
Keywords: | (-)-OTX015, HY-15743,... |
Application: | BRD2 / BRD3 / BRD4 inhibitor |
CAS | 202590-98-5 |
MW: | 492 D |
From 66.00€
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Item number: Cay10749-5
Methylhexanamine (hydrochloride) is a simple aliphatic amine that was once marketed as a nasal decongestant (Forthane) but is now sold as a bodybuilding supplement (Floradrene, Geranamine). It is also sold as a mild stimulant in the form of party pills and has been reported to cause cerebral hemorrhage in a case...
Keywords: | Dimethylamylamine, DMAA, Floradrene, Forthane, Geranamine, NSC 1106, 4-methyl-2-hexanamine, monohydrochloride |
Application: | Analytical reference standard, Simple aliphatic amine, Nasal decongestant, Bodybuilding supplement |
CAS | 13803-74-2 |
MW: | 151.7 D |
From 232.00€
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Item number: Cay17749-5
BRD9 contains a single bromodomain and has five isoforms that are produced by alternative splicing. It is thought to function in chromatin remodeling as part of the SWI/SNF complex. I-BRD9 is a BRD9 bromodomain inhibitor with a pIC50 value of 7.3 and a pKd value of 8.7. It displays 700-fold greater selectivity over...
Keywords: | 5-ethyl-4,5-dihydro-4-oxo-N-(tetrahydro-1,1-dioxido-2H-thiopyran-4-yl)-7-[3-(trifluoromethyl)phenyl]-thieno[3,2-c]pyridine... |
Application: | BRD9 bromodomain inhibitor |
CAS | 1714146-59-4 |
MW: | 497.6 D |
From 98.00€
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Item number: Cay25749-1
CEP-40783 is an inhibitor of the receptor tyrosine kinases Axl and c-MET (IC50s = 7 and 12 nM, respectively). It inhibits Axl in 293GT cells expressing Axl and c-MET in NCI H1299 non-small cell lung cancer (NSCLC) cells with IC50 values of 0.26 and 6 nM, respectively. It also inhibits the receptor tyrosine kinases...
Keywords: | RXDX-106,... |
Application: | AXL / c-Met inhibitor |
CAS | 1437321-24-8 |
MW: | 588.6 D |
From 50.00€
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Item number: Cay35749-1
(-)-beta-Sesquiphellandrene is a sesquiterpene that has been found in Z. officinale and has antiviral and anticancer activities. It reduces rhinovirus IB virus replication in a plaque reduction assay (IC50 = 0.44 µM). (-)-beta-Sesquiphellandrene is cytotoxic to HCT116 cells when used at a concentration of 10...
Keywords: | 3R-[(1S)-1,5-dimethyl-4-hexen-1-yl]-6-methylene-cyclohexene |
Application: | Sesquiterpene, Antiviral / anticancer agent |
CAS | 20307-83-9 |
MW: | 204.4 D |
From 204.00€
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