- Search results for Cay14661-50
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9 products were found matching "Cay14661-50"!
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Item number: Cay14661-1
TRIM33 (TIF1-gamma) is a multi-domain regulator of transcription. It contains a RING domain with E3 ubiquitin ligase activity, two B-boxes, a coiled-coil domain, a PHD domain, and a bromodomain. TRIM33 is necessary for embryogenesis, and mice homozygous for TRIM33 knock-out do not survive to embryonic day 9.5....
Keywords: | E3 Ubiquitin-protein Ligase TRIM33, Ectodermin Homolog, RFG7, TIF1-gamma, Transcriptional Intermediary Factor 1-gamma,... |
Application: | Binding assays |
Expressed in: | E. coli |
2,519.00€
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Item number: Cay14160-50
Acyclovir is a guanosine analog that has antiviral activity in vitro against the herpes simplex viruses, varicella zoster virus, Epstein-Barr virus, cytomegalovirus, and human herpes virus 6 (ID50s = 0.1-63.1 µM). It diffuses freely into cells and is selectively converted into acyclo-guanosine monophosphate by a...
Keywords: | ACV, BW 248U, NSC 645011, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-6H-purin-6-one |
Application: | Antiviral agent, guanosine analog |
CAS | 59277-89-3 |
MW: | 225.2 D |
From 60.00€
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Item number: Cay11466-500
JWH 019 (Cay-13633) is a cannabimimetic indole that shows a high-affinity for both the central cannabinoid (CB1) (Ki = 9.8 nM) and the peripheral cannabinoid (CB2) (Ki = 5.6 nM) receptors. JWH 019 N-(6-hydroxyhexyl) beta-D-Glucuronide is an expected major urinary metabolite of JWH 019, based on the metabolism of...
Keywords: | (2S,3S,4S,5R,6R)-6-((6-(3-(1-naphthoyl)-1H-indol-1-yl)hexyl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid |
Application: | Analytical reference standard, Expected major urinary JWH 019 metabolite |
CAS | 1630023-00-5 |
MW: | 547.6 D |
From 342.00€
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Item number: Cay14616-500
Dorzolamide is an inhibitor of carbonic anhydrase (CA), inhibiting CAII, CAV, CAVI, CAIX, CAXII, CAXIII, and CAXIV with Ki values ranging from 3.5 to 52 nM. It is selective for these isoforms over CAI, CAIII, and CAIV (Kis = 50, 8, and 8.5 µM, respectively). Dorzolamide inhibits carbonic anhydrase in isolated rabbit...
Keywords: | L-671,152, MK-507, (4S,6S)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide, 7,7-dioxide,... |
Application: | Carbonic anhydrase inhibitor |
CAS | 130693-82-2 |
MW: | 360.9 D |
From 65.00€
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Item number: Cay14650-10
13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is a metabolite of PGE2 (Cay-14010) and the primary PGE2 metabolite in plasma. It is formed from PGE2 via a 15-keto PGE2 intermediate by 15-oxo-PG Delta13 reductase. Unlike PGE2, 13,14-dihydro-15-keto PGE2 does not bind effectively to the PGE2...
Keywords: | 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid |
Application: | Bioactive lipid assays |
CAS | 363-23-5 |
MW: | 352.5 D |
From 104.00€
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Item number: Cay16150-50
1-(1-Naphthyl)piperazine (1-NP) is a ligand for serotonin (5-hydroxytryptamine, 5-HT) receptors. It acts as an antagonist for 5-HT at 5-HT1 and 5-HT2 in rat cortical membranes with IC50 values of 6 and 1 nM, respectively. 1-NP also blocks contraction in the rat fundus induced by either 5-HT or tryptamine (IC50 = 1...
Keywords: | 1-NP, 1-(1-naphthalenyl)-piperazine, monohydrochloride |
Application: | 5-HT1 serotonin receptor agonist, 5-HT2 serotonin receptor antagonist |
CAS | 104113-71-5 |
MW: | 248.7 D |
From 98.00€
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Item number: Cay14664-50
NS 6180 is an inhibitor of the intermediate-conductance calcium-activated potassium channel 3.1 (IKCa1/KCa3.1, IC50 = 9.4 nM in HEK293 cells expressing the human channel). It inhibits hyperpolarization of human, mouse, and rat erythrocytes induced by the calcium ionophore A23187 (Cay-11016) (IC50s = 14, 15, and 9...
Keywords: | 4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one |
Application: | KCa3.1 channel blocker |
CAS | 353262-04-1 |
MW: | 323.3 D |
From 109.00€
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Item number: Cay14662-50
Zaltoprofen is a cyclooxygenase (COX) inhibitor that displays slight preferential inhibition for COX-2 (IC50s = 1.3 and 0.34 µM for COX-1 and COX-2, respectively). Independent of COX inhibition, zaltoprofen has also been reported to inhibit bradykinin-induced nociceptive responses by blocking the activation of...
Keywords: | CN 100, Soleton, 10,11-dihydro-a-methyl-10-oxo-dibenzo[b,f]thiepin-2-acetic acid |
Application: | COX inhibitor |
CAS | 74711-43-6 |
MW: | 298.4 D |
From 115.00€
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Item number: Cay14667-50
Sphingosine-1-phosphate (S1P) is an extracellular lipid mediator whose major effects are mediated through five distinct G protein-coupled receptors S1P1/EDG-1, S1P2/EDG-5, S1P3/EDG-3, S1P4/EDG-6, and S1P5/EDG-8. S1P4 couples to Galphai, Galphao, and Galpha12/13 proteins leading to the stimulation of MAPK/ERK...
Keywords: | CID-49835928, ML-248,... |
Application: | S1PR4 / EDG6 agonist |
CAS | 1345858-76-5 |
MW: | 405.5 D |
From 50.00€
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