3 products were found matching "Cay14661-25"!
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7-dehydro Cholesterol
Item number: Cay14612-5
7-dehydro Cholesterol (7-DHC) is an immediate precursor of cholesterol. It is reduced to cholesterol by the enzyme 3beta-hydroxysterol-Delta7-reductase (DHCR7) in the last step of cholesterol biosynthesis. 7-DHC accumulates in Smith-Lemli-Opitz syndrome (SLOS), a disorder characterized by a mutation in the DHCR7...
| Keywords: | 7-DHC, NSC 18159, Provitamin D3, Delta7-Cholesterol, cholesta-5,7-dien-3beta-ol |
| Application: | Cholesterol precursor |
| CAS | 434-16-2 |
| MW: | 384.6 D |
From 52.00€
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AAF-CMK (trifluoroacetate salt)
Item number: Cay14461-25
Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK is an irreversible inhibitor of TPPII commonly used at 10-100 µM. It does not significantly interfere with the chymotrypsin-like activity of the proteasome....
| Keywords: | N-Ala-Ala-Phe-CMK, Tripeptidyl Peptidase Inhibitor II,... |
| Application: | TPPII inhibitor, Bleomycin hydrolase and aminopeptidase inhibitor |
| CAS | 184901-82-4 |
| MW: | 453.8 D |
From 84.00€
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AY 9944
Item number: Cay14611-25
AY 9944 prevents cholesterol biosynthesis by inhibiting the 7-dehydro cholesterol Delta7-reductase (DHCR7) enzyme (IC50 = 13 nM), which interferes with the conversion of 7-dehydro cholesterol (Cay-14612) to cholesterol. Furthermore, by upregulating the expression of DHCR7, AY 9944 can block Hedgehog signaling at the...
| Keywords: | trans-N1,N4-bis[(2-chlorophenyl)methyl]-1,4-cyclohexanedimethanamine, dihydrochloride |
| Application: | DHCR7 inhibitor |
| CAS | 366-93-8 |
| MW: | 464.3 D |
From 46.00€
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